1QCAA

Quadruple mutant q92c, n146f, y168f, i172v type iii cat complexed with fusidic acid. crystals grown at ph 6.3. x-ray data collected at room temperature
Total Genus 55
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
55
sequence length
213
structure length
211
Chain Sequence
MNYTKFDVKNWVRREHFEFYRHRLPCGFSLTSKIDITTLKKSLDDSAYKFYPVMIYLIAQAVNQFDELRMAIKDDELIVWDSVDPCFTVFHQETETFSALSCPYSSDIDQFMVNYLSVMERYKSDTKLFPQGPENHLFISALPWVNFDSFNLNVANFTDFFAPVITMAKYQQEGDRLLLPLSVQVHHAVCDGFHVARFINRLQELCNSKLK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Steroid recognition by chloramphenicol acetyltransferase: engineering and structural analysis of a high affinity fusidic acid binding site.
pubmed doi rcsb
molecule tags Transferase (acyltransferase)
source organism Shigella flexneri
molecule keywords TYPE III CHLORAMPHENICOL ACETYLTRANSFERASE
total genus 55
structure length 211
sequence length 213
ec nomenclature ec 2.3.1.28: Chloramphenicol O-acetyltransferase.
pdb deposition date 1995-08-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00302 CAT Chloramphenicol acetyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.559.10 Alpha Beta 2-Layer Sandwich Chloramphenicol Acetyltransferase Chloramphenicol acetyltransferase-like domain 1qcaA00
4HVMA 1EACA 1XMDA 5KJWA 4CLAA 3L60A 1XMCA 1EABA 1XL8A 5DU9A 1EAEA 3B30A 2II4A 1Q9JA 3FOTA 1DPCA 1SCZA 5FALA 1Q23A 2JGPA 2VSQA 3U9FA 1XL7A 1DPBA 4JN5A 1EADA 5KJVA 2XR7A 1L5AA 2E1VA 2BGHA 5KJTA 1CLAA 5FANA 1C4TA 4JN3A 4N72A 5KJUA 1EAFA 1QCAA 2II5A 2E1TA 4KECA 3U9BA 2I9DA 5KJSA 2RKTA 2XHGA 3B2SA 1PD5A 3FP0A 1CIAA 4G22A 5DUAA 5T3EA 2IHWA 3MAEA 2CLAA 2E1UA 2II3A 1EAAA 1DPDA 2RKVA 2ZBAA 1NOCB 4G0BA 3CLAA 4KE4A 4G2MA 1E2OA
chains in the Genus database with same CATH superfamily
3L60A 1XMCA 2FY5A 1NDIA 2RCUA 1DPCA 1Q23A 4EYWA 2XR7A 2BGHA 4KECA 5KJSA 2E1TA 3B2SA 2E1UA 2II3A 1DPDA 1NOCB 4EP9A 4JN3A 1E2OA 5KJWA 1S5OA 1EABA 1Q6XA 2II4A 1Q9JA 1T7QA 5FALA 2JGPA 3U9FA 1DPBA 2II5A 1QCAA 3U9BA 4EPHA 1CIAA 5T3EA 2IHWA 3MAEA 2CLAA 4G0BA 3CLAA 4G2MA 1EACA 1XMDA 4CLAA 5DU9A 2FW3A 1SCZA 2H3UA 1NM8A 1XL7A 4JN5A 5KJVA 2H4TA 1NDBA 1L5AA 5FANA 4N72A 2H3WA 2RKTA 2XHGA 3FP0A 4G22A 5DUAA 1EAAA 2RKVA 2ZBAA 4KE4A 4HVMA 1T7OA 1XL8A 1T1UA 1EAEA 2FY2A 3B30A 2FY4A 3FOTA 1NDFA 2VSQA 2FY3A 1EADA 2E1VA 5KJTA 1CLAA 1C4TA 5KJUA 1EAFA 2H3PA 2DEBA 2I9DA 2FYOA 1PD5A 1T7NA
chains in the Genus database with same CATH topology
4HVMA 1EACA 1XMDA 5KJWA 4CLAA 3L60A 1XMCA 1EABA 1XL8A 5DU9A 1EAEA 3B30A 2II4A 1Q9JA 3FOTA 1DPCA 1SCZA 5FALA 1Q23A 2JGPA 2VSQA 3U9FA 1XL7A 1DPBA 4JN5A 1EADA 5KJVA 2XR7A 1L5AA 2E1VA 2BGHA 5KJTA 1CLAA 5FANA 1C4TA 4JN3A 4N72A 5KJUA 1EAFA 1QCAA 2II5A 2E1TA 4KECA 3U9BA 2I9DA 5KJSA 2RKTA 2XHGA 3B2SA 1PD5A 3FP0A 1CIAA 4G22A 5DUAA 5T3EA 2IHWA 3MAEA 2CLAA 2E1UA 2II3A 1EAAA 1DPDA 2RKVA 2ZBAA 1NOCB 4G0BA 3CLAA 4KE4A 4G2MA 1E2OA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HVM A;  1EAC A;  1XMD A;  5KJW A;  4CLA A;  3L60 A;  1XMC A;  1EAB A;  1XL8 A;  5DU9 A;  1EAE A;  3B30 A;  2II4 A;  1Q9J A;  3FOT A;  1DPC A;  1SCZ A;  5FAL A;  1Q23 A;  2JGP A;  2VSQ A;  3U9F A;  1XL7 A;  1DPB A;  4JN5 A;  1EAD A;  5KJV A;  2XR7 A;  1L5A A;  2E1V A;  2BGH A;  5KJT A;  1CLA A;  5FAN A;  1C4T A;  4JN3 A;  4N72 A;  5KJU A;  1EAF A;  1QCA A;  2II5 A;  2E1T A;  4KEC A;  3U9B A;  2I9D A;  5KJS A;  2RKT A;  2XHG A;  3B2S A;  1PD5 A;  3FP0 A;  1CIA A;  4G22 A;  5DUA A;  5T3E A;  2IHW A;  3MAE A;  2CLA A;  2E1U A;  2II3 A;  1EAA A;  1DPD A;  2RKV A;  2ZBA A;  1NOC B;  4G0B A;  3CLA A;  4KE4 A;  4G2M A;  1E2O A; 
#chains in the Genus database with same CATH topology
 3L60 A;  1XMC A;  2FY5 A;  1NDI A;  2RCU A;  1DPC A;  1Q23 A;  4EYW A;  2XR7 A;  2BGH A;  4KEC A;  5KJS A;  2E1T A;  3B2S A;  2E1U A;  2II3 A;  1DPD A;  1NOC B;  4EP9 A;  4JN3 A;  1E2O A;  5KJW A;  1S5O A;  1EAB A;  1Q6X A;  2II4 A;  1Q9J A;  1T7Q A;  5FAL A;  2JGP A;  3U9F A;  1DPB A;  2II5 A;  1QCA A;  3U9B A;  4EPH A;  1CIA A;  5T3E A;  2IHW A;  3MAE A;  2CLA A;  4G0B A;  3CLA A;  4G2M A;  1EAC A;  1XMD A;  4CLA A;  5DU9 A;  2FW3 A;  1SCZ A;  2H3U A;  1NM8 A;  1XL7 A;  4JN5 A;  5KJV A;  2H4T A;  1NDB A;  1L5A A;  5FAN A;  4N72 A;  2H3W A;  2RKT A;  2XHG A;  3FP0 A;  4G22 A;  5DUA A;  1EAA A;  2RKV A;  2ZBA A;  4KE4 A;  4HVM A;  1T7O A;  1XL8 A;  1T1U A;  1EAE A;  2FY2 A;  3B30 A;  2FY4 A;  3FOT A;  1NDF A;  2VSQ A;  2FY3 A;  1EAD A;  2E1V A;  5KJT A;  1CLA A;  1C4T A;  5KJU A;  1EAF A;  2H3P A;  2DEB A;  2I9D A;  2FYO A;  1PD5 A;  1T7N A; 
#chains in the Genus database with same CATH homology
 4HVM A;  1EAC A;  1XMD A;  5KJW A;  4CLA A;  3L60 A;  1XMC A;  1EAB A;  1XL8 A;  5DU9 A;  1EAE A;  3B30 A;  2II4 A;  1Q9J A;  3FOT A;  1DPC A;  1SCZ A;  5FAL A;  1Q23 A;  2JGP A;  2VSQ A;  3U9F A;  1XL7 A;  1DPB A;  4JN5 A;  1EAD A;  5KJV A;  2XR7 A;  1L5A A;  2E1V A;  2BGH A;  5KJT A;  1CLA A;  5FAN A;  1C4T A;  4JN3 A;  4N72 A;  5KJU A;  1EAF A;  1QCA A;  2II5 A;  2E1T A;  4KEC A;  3U9B A;  2I9D A;  5KJS A;  2RKT A;  2XHG A;  3B2S A;  1PD5 A;  3FP0 A;  1CIA A;  4G22 A;  5DUA A;  5T3E A;  2IHW A;  3MAE A;  2CLA A;  2E1U A;  2II3 A;  1EAA A;  1DPD A;  2RKV A;  2ZBA A;  1NOC B;  4G0B A;  3CLA A;  4KE4 A;  4G2M A;  1E2O A; 
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