1S5OA

Structural and mutational characterization of l-carnitine binding to human carnitine acetyltransferase
Total Genus 215
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
215
sequence length
591
structure length
591
Chain Sequence
HHTDPLPRLPVPPLQQSLDHYLKALQPIVSEEEWAHTKQLVDEFQASGGVGERLQKGLERRARKTENWLSEWWLKTAYLQYRQPVVIYSSPGVMLPKQDFVDLQGQLRFAAKLIEGVLDFKVMIDNETLPVEYLGGKPLCMNQYYQILSSCRVPGPKQDTVSNFSKTKKPPTHITVVHNYQFFELDVYHSDGTPLTADQIFVQLEKIWNSSLQTNKEPVGILTSNHRNSWAKAYNTLIKDKVNRDSVRSIQKSIFTVCLDATMPRVSEDVYRSHVAGQMLHGGGSRLNSGNRWFDKTLQFIVAEDGSCGLVYEHAAAEGPPIVTLLDYVIEYTKKPELVRSPMVPLPMPKKLRFNITPEIKSDIEKAKQNLSIMIQDLDITVMVFHHFGKDFPKSEKLSPDAFIQMALQLAYYRIYGQACATYESASLRMFHLGRTDTIRSASMDSLTFVKAMDDSSVTEHQKVELLRKAVQAHRGYTDRAIRGEAFDRHLLGLKLQAIEDLVSTPDIFMDTSYAIAMHFHLSTSQVPAKTDCVMFFGPVVPDGYGVCYNPMEAHINFSLSAYNSCAETNAARLAHYLEKALLDMRALLQS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural and mutational characterization of l-carnitine binding to human carnitine acetyltransferase.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords carnitine acetyltransferase isoform 2
total genus 215
structure length 591
sequence length 591
ec nomenclature ec 2.3.1.7: Carnitine O-acetyltransferase.
pdb deposition date 2004-01-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00755 Carn_acyltransf Choline/Carnitine o-acyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.559.40 Alpha Beta 2-Layer Sandwich Chloramphenicol Acetyltransferase Chloramphenicol Acetyltransferase 1s5oA01
3.30.559.70 Alpha Beta 2-Layer Sandwich Chloramphenicol Acetyltransferase Chloramphenicol Acetyltransferase 1s5oA02
2H4TA 4EYWA 1T7NA 1NDIA 2DEBA 1Q6XA 1NDBA 2FY5A 2H3UA 2FY4A 2H3PA 1S5OA 2FY2A 1T7QA 1T1UA 2FYOA 1T7OA 1NDFA 2FY3A 2RCUA 2FW3A 4EPHA 2H3WA 1NM8A 4EP9A
chains in the Genus database with same CATH superfamily
2BGHA 2RKTA 2DEBA 1DPCA 4KE4A 1SCZA 2H3UA 2JGPA 2RKVA 2ZBAA 3U9BA 1EABA 1T7QA 3FP0A 1T7OA 2II3A 2VSQA 1NDFA 2RCUA 4EPHA 1CIAA 1EACA 1NM8A 4EP9A 4EYWA 1T7NA 2I9DA 5KJUA 4CLAA 1NOCB 1Q6XA 1XL8A 2CLAA 5FANA 1L5AA 3L60A 5KJWA 1EAAA 5DUAA 1S5OA 2E1VA 2FY2A 5KJSA 1XMCA 4HVMA 2FY3A 5T3EA 2II5A 2II4A 1EAFA 3CLAA 5FALA 3MAEA 5DU9A 1QCAA 1E2OA 1DPBA 2IHWA 1NDBA 5KJVA 3U9FA 3B2SA 5KJTA 1PD5A 1CLAA 2FYOA 1C4TA 4N72A 1EAEA 2XR7A 2FW3A 4G22A 4JN3A 3B30A 1Q23A 1XL7A 2E1UA 2H4TA 1DPDA 1XMDA 1NDIA 1EADA 3FOTA 2E1TA 4G2MA 2FY5A 2FY4A 2H3PA 1Q9JA 4G0BA 1T1UA 4JN5A 4KECA 2H3WA 2XHGA
chains in the Genus database with same CATH topology
2H4TA 4EYWA 1T7NA 1NDIA 5DU9A 2DEBA 3FOTA 1Q6XA 1L5AA 1NDBA 2FY5A 2H3UA 5DUAA 2FY4A 2H3PA 2JGPA 1S5OA 1Q9JA 2FY2A 1T7QA 1T1UA 2FYOA 4HVMA 3FP0A 1T7OA 2VSQA 4JN5A 1NDFA 2FY3A 2RCUA 5T3EA 2FW3A 4EPHA 4JN3A 2H3WA 1NM8A 2XHGA 4EP9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2H4T A;  4EYW A;  1T7N A;  1NDI A;  2DEB A;  1Q6X A;  1NDB A;  2FY5 A;  2H3U A;  2FY4 A;  2H3P A;  1S5O A;  2FY2 A;  1T7Q A;  1T1U A;  2FYO A;  1T7O A;  1NDF A;  2FY3 A;  2RCU A;  2FW3 A;  4EPH A;  2H3W A;  1NM8 A;  4EP9 A; 
#chains in the Genus database with same CATH topology
 2BGH A;  2RKT A;  2DEB A;  1DPC A;  4KE4 A;  1SCZ A;  2H3U A;  2JGP A;  2RKV A;  2ZBA A;  3U9B A;  1EAB A;  1T7Q A;  3FP0 A;  1T7O A;  2II3 A;  2VSQ A;  1NDF A;  2RCU A;  4EPH A;  1CIA A;  1EAC A;  1NM8 A;  4EP9 A;  4EYW A;  1T7N A;  2I9D A;  5KJU A;  4CLA A;  1NOC B;  1Q6X A;  1XL8 A;  2CLA A;  5FAN A;  1L5A A;  3L60 A;  5KJW A;  1EAA A;  5DUA A;  1S5O A;  2E1V A;  2FY2 A;  5KJS A;  1XMC A;  4HVM A;  2FY3 A;  5T3E A;  2II5 A;  2II4 A;  1EAF A;  3CLA A;  5FAL A;  3MAE A;  5DU9 A;  1QCA A;  1E2O A;  1DPB A;  2IHW A;  1NDB A;  5KJV A;  3U9F A;  3B2S A;  5KJT A;  1PD5 A;  1CLA A;  2FYO A;  1C4T A;  4N72 A;  1EAE A;  2XR7 A;  2FW3 A;  4G22 A;  4JN3 A;  3B30 A;  1Q23 A;  1XL7 A;  2E1U A;  2H4T A;  1DPD A;  1XMD A;  1NDI A;  1EAD A;  3FOT A;  2E1T A;  4G2M A;  2FY5 A;  2FY4 A;  2H3P A;  1Q9J A;  4G0B A;  1T1U A;  4JN5 A;  4KEC A;  2H3W A;  2XHG A; 
#chains in the Genus database with same CATH homology
 2H4T A;  4EYW A;  1T7N A;  1NDI A;  5DU9 A;  2DEB A;  3FOT A;  1Q6X A;  1L5A A;  1NDB A;  2FY5 A;  2H3U A;  5DUA A;  2FY4 A;  2H3P A;  2JGP A;  1S5O A;  1Q9J A;  2FY2 A;  1T7Q A;  1T1U A;  2FYO A;  4HVM A;  3FP0 A;  1T7O A;  2VSQ A;  4JN5 A;  1NDF A;  2FY3 A;  2RCU A;  5T3E A;  2FW3 A;  4EPH A;  4JN3 A;  2H3W A;  1NM8 A;  2XHG A;  4EP9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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