1S5OA

Structural and mutational characterization of l-carnitine binding to human carnitine acetyltransferase
Total Genus 215
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
215
sequence length
591
structure length
591
Chain Sequence
HHTDPLPRLPVPPLQQSLDHYLKALQPIVSEEEWAHTKQLVDEFQASGGVGERLQKGLERRARKTENWLSEWWLKTAYLQYRQPVVIYSSPGVMLPKQDFVDLQGQLRFAAKLIEGVLDFKVMIDNETLPVEYLGGKPLCMNQYYQILSSCRVPGPKQDTVSNFSKTKKPPTHITVVHNYQFFELDVYHSDGTPLTADQIFVQLEKIWNSSLQTNKEPVGILTSNHRNSWAKAYNTLIKDKVNRDSVRSIQKSIFTVCLDATMPRVSEDVYRSHVAGQMLHGGGSRLNSGNRWFDKTLQFIVAEDGSCGLVYEHAAAEGPPIVTLLDYVIEYTKKPELVRSPMVPLPMPKKLRFNITPEIKSDIEKAKQNLSIMIQDLDITVMVFHHFGKDFPKSEKLSPDAFIQMALQLAYYRIYGQACATYESASLRMFHLGRTDTIRSASMDSLTFVKAMDDSSVTEHQKVELLRKAVQAHRGYTDRAIRGEAFDRHLLGLKLQAIEDLVSTPDIFMDTSYAIAMHFHLSTSQVPAKTDCVMFFGPVVPDGYGVCYNPMEAHINFSLSAYNSCAETNAARLAHYLEKALLDMRALLQS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural and mutational characterization of l-carnitine binding to human carnitine acetyltransferase.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords carnitine acetyltransferase isoform 2
total genus 215
structure length 591
sequence length 591
ec nomenclature ec 2.3.1.7: Carnitine O-acetyltransferase.
pdb deposition date 2004-01-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00755 Carn_acyltransf Choline/Carnitine o-acyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.559.40 Alpha Beta 2-Layer Sandwich Chloramphenicol Acetyltransferase Chloramphenicol Acetyltransferase 1s5oA01
3.30.559.70 Alpha Beta 2-Layer Sandwich Chloramphenicol Acetyltransferase Chloramphenicol Acetyltransferase 1s5oA02
2FY2A 2H4TA 1T1UA 1NM8A 1NDFA 1NDBA 2H3WA 1Q6XA 1T7OA 2H3UA 4EPHA 2FYOA 1NDIA 2H3PA 2FY3A 4EP9A 1S5OA 2RCUA 2FW3A 2FY5A 1T7NA 1T7QA 4EYWA 2FY4A 2DEBA
chains in the Genus database with same CATH superfamily
2FY2A 1DPBA 1EACA 5FALA 1L5AA 5DUAA 5KJSA 1CLAA 1SCZA 2H3PA 1EAFA 2I9DA 2FY5A 1T7NA 4JN3A 1E2OA 1C4TA 1EABA 2DEBA 5KJUA 1EAAA 1QCAA 1T1UA 1PD5A 2IHWA 4KE4A 1NDFA 1NDBA 1EADA 5FANA 4EPHA 2FYOA 1NDIA 1XL8A 3B30A 5T3EA 2FY3A 4N72A 3FOTA 5KJVA 2VSQA 4JN5A 1Q23A 1EAEA 5KJWA 2JGPA 4G2MA 2FY4A 1XMCA 2XHGA 4HVMA 3U9FA 1NM8A 2H3WA 1Q6XA 3CLAA 3FP0A 4EP9A 2RCUA 3MAEA 2II5A 1DPDA 2ZBAA 1CIAA 1DPCA 1T7QA 2E1UA 2RKVA 2XR7A 2E1VA 2II3A 1NOCB 2RKTA 4KECA 2H4TA 4CLAA 3B2SA 5DU9A 2II4A 1Q9JA 2CLAA 1XMDA 1T7OA 2H3UA 4G0BA 3L60A 5KJTA 1XL7A 1S5OA 4G22A 3U9BA 2FW3A 2BGHA 4EYWA 2E1TA
chains in the Genus database with same CATH topology
2FY2A 2H4TA 1T1UA 2XHGA 4HVMA 1NM8A 1NDFA 1NDBA 2H3WA 5DU9A 1Q6XA 1L5AA 1Q9JA 5DUAA 1T7OA 2H3UA 4EPHA 2FYOA 1NDIA 3FP0A 2H3PA 5T3EA 2FY3A 4EP9A 1S5OA 2RCUA 2FW3A 3FOTA 2FY5A 2VSQA 1T7NA 4JN3A 1T7QA 4JN5A 4EYWA 2JGPA 2FY4A 2DEBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2FY2 A;  2H4T A;  1T1U A;  1NM8 A;  1NDF A;  1NDB A;  2H3W A;  1Q6X A;  1T7O A;  2H3U A;  4EPH A;  2FYO A;  1NDI A;  2H3P A;  2FY3 A;  4EP9 A;  1S5O A;  2RCU A;  2FW3 A;  2FY5 A;  1T7N A;  1T7Q A;  4EYW A;  2FY4 A;  2DEB A; 
#chains in the Genus database with same CATH topology
 2FY2 A;  1DPB A;  1EAC A;  5FAL A;  1L5A A;  5DUA A;  5KJS A;  1CLA A;  1SCZ A;  2H3P A;  1EAF A;  2I9D A;  2FY5 A;  1T7N A;  4JN3 A;  1E2O A;  1C4T A;  1EAB A;  2DEB A;  5KJU A;  1EAA A;  1QCA A;  1T1U A;  1PD5 A;  2IHW A;  4KE4 A;  1NDF A;  1NDB A;  1EAD A;  5FAN A;  4EPH A;  2FYO A;  1NDI A;  1XL8 A;  3B30 A;  5T3E A;  2FY3 A;  4N72 A;  3FOT A;  5KJV A;  2VSQ A;  4JN5 A;  1Q23 A;  1EAE A;  5KJW A;  2JGP A;  4G2M A;  2FY4 A;  1XMC A;  2XHG A;  4HVM A;  3U9F A;  1NM8 A;  2H3W A;  1Q6X A;  3CLA A;  3FP0 A;  4EP9 A;  2RCU A;  3MAE A;  2II5 A;  1DPD A;  2ZBA A;  1CIA A;  1DPC A;  1T7Q A;  2E1U A;  2RKV A;  2XR7 A;  2E1V A;  2II3 A;  1NOC B;  2RKT A;  4KEC A;  2H4T A;  4CLA A;  3B2S A;  5DU9 A;  2II4 A;  1Q9J A;  2CLA A;  1XMD A;  1T7O A;  2H3U A;  4G0B A;  3L60 A;  5KJT A;  1XL7 A;  1S5O A;  4G22 A;  3U9B A;  2FW3 A;  2BGH A;  4EYW A;  2E1T A; 
#chains in the Genus database with same CATH homology
 2FY2 A;  2H4T A;  1T1U A;  2XHG A;  4HVM A;  1NM8 A;  1NDF A;  1NDB A;  2H3W A;  5DU9 A;  1Q6X A;  1L5A A;  1Q9J A;  5DUA A;  1T7O A;  2H3U A;  4EPH A;  2FYO A;  1NDI A;  3FP0 A;  2H3P A;  5T3E A;  2FY3 A;  4EP9 A;  1S5O A;  2RCU A;  2FW3 A;  3FOT A;  2FY5 A;  2VSQ A;  1T7N A;  4JN3 A;  1T7Q A;  4JN5 A;  4EYW A;  2JGP A;  2FY4 A;  2DEB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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