1T1UA

Structural insights and functional implications of choline acetyltransferase
Total Genus 221
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
221
sequence length
597
structure length
597
Chain Sequence
ELDLPKLPVPPLQQTLATYLQCMQHLVPEEQFRKSQAIVKRFGAPGGLGETLQEKLLERQEKTANWVSEYWLNDMYLNNRLALPVNSSPAVIFARQHFQDTNDQLRFAACLISGVLSYKTLLDSHSLPTDWAKGQLSGQPLCMKQYYRLFSSYRLPGHTQDTLVAQKSSIMPEPEHVIVACCNQFFVLDVVINFRRLSEGDLFTQLRKIVKMASNEDERLPPIGLLTSDGRSEWAKARTVLLKDSTNRDSLDMIERCICLVCLDGPGTGELSDTHRALQLLHGGGCSLNGANRWYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHLLKHMMTSNKKLVRADSVSELPAPRRLRWKCSPETQGHLASSAEKLQRIVKNLDFIVYKFDNYGKTFIKKQKYSPDGFIQVALQLAYYRLYQRLVPTYESASIRRFQEGRVDNIRSATPEALAFVQAMTDHKAAMPASEKLQLLQTAMQAQTEYTVMAITGMAIDNHLLALRELARDLCKEPPEMFMDETYLMSNRFVLSTSQVPTTMEMFCCYGPVVPNGYGACYNPQPEAITFCISSFHSCKETSSVEFAEAVGASLVDMRDLCSS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural insights and functional implications of choline acetyltransferase
pubmed doi rcsb
molecule tags Transferase
source organism Rattus norvegicus
molecule keywords Choline O-acetyltransferase
total genus 221
structure length 597
sequence length 597
ec nomenclature ec 2.3.1.6: Choline O-acetyltransferase.
pdb deposition date 2004-04-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00755 Carn_acyltransf Choline/Carnitine o-acyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.559.40 Alpha Beta 2-Layer Sandwich Chloramphenicol Acetyltransferase Chloramphenicol Acetyltransferase 1t1uA01
3.30.559.70 Alpha Beta 2-Layer Sandwich Chloramphenicol Acetyltransferase Chloramphenicol Acetyltransferase 1t1uA02
2H3PA 1T7QA 1S5OA 2DEBA 1T7NA 2FY5A 2FY2A 4EP9A 1NDIA 4EYWA 2H3WA 1NM8A 2H3UA 4EPHA 2FYOA 1NDFA 2FY3A 1NDBA 2FY4A 2FW3A 1Q6XA 1T7OA 2H4TA 2RCUA 1T1UA
chains in the Genus database with same CATH superfamily
1T7QA 1XMDA 3FP0A 2FY5A 1CLAA 1XL8A 1EAAA 1NDIA 4EYWA 2JGPA 4G22A 1XMCA 5KJWA 1EACA 2H3UA 2FYOA 5FALA 4KE4A 2RKTA 5KJSA 2RKVA 4JN3A 1T1UA 4G2MA 2E1VA 4JN5A 4N72A 3B2SA 2ZBAA 1T7NA 2CLAA 3CLAA 3FOTA 1DPBA 3MAEA 2VSQA 1C4TA 5T3EA 1NDFA 1NDBA 2FY4A 2E1TA 2XR7A 2II3A 2FW3A 2RCUA 4G0BA 5KJUA 5DU9A 4KECA 1Q9JA 2DEBA 2FY2A 1L5AA 4EP9A 2H3WA 1NM8A 3L60A 1QCAA 1Q23A 2II5A 1E2OA 1DPCA 1EAEA 5KJVA 1T7OA 2I9DA 1PD5A 5KJTA 1EAFA 3B30A 1CIAA 2II4A 3U9BA 2H3PA 1S5OA 5DUAA 1EADA 3U9FA 2BGHA 1DPDA 2E1UA 4HVMA 1EABA 4EPHA 1SCZA 4CLAA 1NOCB 2FY3A 2XHGA 2IHWA 1XL7A 5FANA 1Q6XA 2H4TA
chains in the Genus database with same CATH topology
2H3PA 5DU9A 1Q9JA 1T7QA 1S5OA 2DEBA 3FP0A 4JN5A 5DUAA 1T7NA 2FY5A 2FY2A 1L5AA 4EP9A 4HVMA 1NDIA 4EYWA 2JGPA 3FOTA 2H3WA 1NM8A 2H3UA 4EPHA 2VSQA 2FYOA 5T3EA 1NDFA 2FY3A 2XHGA 1NDBA 2FY4A 2FW3A 1Q6XA 1T7OA 2H4TA 2RCUA 4JN3A 1T1UA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2H3P A;  1T7Q A;  1S5O A;  2DEB A;  1T7N A;  2FY5 A;  2FY2 A;  4EP9 A;  1NDI A;  4EYW A;  2H3W A;  1NM8 A;  2H3U A;  4EPH A;  2FYO A;  1NDF A;  2FY3 A;  1NDB A;  2FY4 A;  2FW3 A;  1Q6X A;  1T7O A;  2H4T A;  2RCU A;  1T1U A; 
#chains in the Genus database with same CATH topology
 1T7Q A;  1XMD A;  3FP0 A;  2FY5 A;  1CLA A;  1XL8 A;  1EAA A;  1NDI A;  4EYW A;  2JGP A;  4G22 A;  1XMC A;  5KJW A;  1EAC A;  2H3U A;  2FYO A;  5FAL A;  4KE4 A;  2RKT A;  5KJS A;  2RKV A;  4JN3 A;  1T1U A;  4G2M A;  2E1V A;  4JN5 A;  4N72 A;  3B2S A;  2ZBA A;  1T7N A;  2CLA A;  3CLA A;  3FOT A;  1DPB A;  3MAE A;  2VSQ A;  1C4T A;  5T3E A;  1NDF A;  1NDB A;  2FY4 A;  2E1T A;  2XR7 A;  2II3 A;  2FW3 A;  2RCU A;  4G0B A;  5KJU A;  5DU9 A;  4KEC A;  1Q9J A;  2DEB A;  2FY2 A;  1L5A A;  4EP9 A;  2H3W A;  1NM8 A;  3L60 A;  1QCA A;  1Q23 A;  2II5 A;  1E2O A;  1DPC A;  1EAE A;  5KJV A;  1T7O A;  2I9D A;  1PD5 A;  5KJT A;  1EAF A;  3B30 A;  1CIA A;  2II4 A;  3U9B A;  2H3P A;  1S5O A;  5DUA A;  1EAD A;  3U9F A;  2BGH A;  1DPD A;  2E1U A;  4HVM A;  1EAB A;  4EPH A;  1SCZ A;  4CLA A;  1NOC B;  2FY3 A;  2XHG A;  2IHW A;  1XL7 A;  5FAN A;  1Q6X A;  2H4T A; 
#chains in the Genus database with same CATH homology
 2H3P A;  5DU9 A;  1Q9J A;  1T7Q A;  1S5O A;  2DEB A;  3FP0 A;  4JN5 A;  5DUA A;  1T7N A;  2FY5 A;  2FY2 A;  1L5A A;  4EP9 A;  4HVM A;  1NDI A;  4EYW A;  2JGP A;  3FOT A;  2H3W A;  1NM8 A;  2H3U A;  4EPH A;  2VSQ A;  2FYO A;  5T3E A;  1NDF A;  2FY3 A;  2XHG A;  1NDB A;  2FY4 A;  2FW3 A;  1Q6X A;  1T7O A;  2H4T A;  2RCU A;  4JN3 A;  1T1U A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...