1T1U | Genus

Total Genus 221

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	221
sequence length	597
structure length	597
Chain Sequence	ELDLPKLPVPPLQQTLATYLQCMQHLVPEEQFRKSQAIVKRFGAPGGLGETLQEKLLERQEKTANWVSEYWLNDMYLNNRLALPVNSSPAVIFARQHFQDTNDQLRFAACLISGVLSYKTLLDSHSLPTDWAKGQLSGQPLCMKQYYRLFSSYRLPGHTQDTLVAQKSSIMPEPEHVIVACCNQFFVLDVVINFRRLSEGDLFTQLRKIVKMASNEDERLPPIGLLTSDGRSEWAKARTVLLKDSTNRDSLDMIERCICLVCLDGPGTGELSDTHRALQLLHGGGCSLNGANRWYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHLLKHMMTSNKKLVRADSVSELPAPRRLRWKCSPETQGHLASSAEKLQRIVKNLDFIVYKFDNYGKTFIKKQKYSPDGFIQVALQLAYYRLYQRLVPTYESASIRRFQEGRVDNIRSATPEALAFVQAMTDHKAAMPASEKLQLLQTAMQAQTEYTVMAITGMAIDNHLLALRELARDLCKEPPEMFMDETYLMSNRFVLSTSQVPTTMEMFCCYGPVVPNGYGACYNPQPEAITFCISSFHSCKETSSVEFAEAVGASLVDMRDLCSS

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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Viewer cachePut cache://localLOAD_/file/5cfc1342de8926c64a36015f/pdb.gz

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The Resolver thinks Pdb

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Time for openFile(/file/5cfc1342de8926c64a36015f/pdb.gz): 1840 ms

reading 597 atoms

ModelSet: haveSymmetry:false haveUnitcells:false haveFractionalCoord:false

1 model in this collection. Use getProperty "modelInfo" or getProperty "auxiliaryInfo" to inspect them.

Default Van der Waals type for model set to Jmol

597 atoms created

ModelSet: autobonding; use autobond=false to not generate bonds automatically

Time for creating model: 36 ms

Adding embedded #jmolscript: select ({0:596});backbone only;select *;

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Transferase
source organism	Rattus norvegicus
publication title	Structural insights and functional implications of choline acetyltransferase pubmed doi rcsb
molecule keywords	Choline O-acetyltransferase
total genus	221
structure length	597
sequence length	597
ec nomenclature	ec 2.3.1.6: Choline O-acetyltransferase.
pdb deposition date	2004-04-18

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00755	Carn_acyltransf	Choline/Carnitine o-acyltransferase

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.30.559.40	Alpha Beta	2-Layer Sandwich	Chloramphenicol Acetyltransferase	Chloramphenicol Acetyltransferase	1t1uA01
3.30.559.70	Alpha Beta	2-Layer Sandwich	Chloramphenicol Acetyltransferase	Chloramphenicol Acetyltransferase	1t1uA02

1NDFA 1T1UA 2DEBA 2H3PA 2H3WA 4EYWA 4EP9A 1NM8A 2H4TA 1Q6XA 1NDBA 2FY4A 1NDIA 2RCUA 2FW3A 2FY5A 2H3UA 2FY3A 2FY2A 1T7QA 1T7NA 4EPHA 1T7OA 1S5OA 2FYOA
chains in the Genus database with same CATH superfamily

2E1TA 1QCAA 2ZBAA 2JGPA 4CLAA 2RKTA 1Q9JA 2VSQA 1EAFA 2H3WA 2H4TA 2BGHA 4G0BA 1E2OA 2FY3A 1T7QA 4EPHA 1EAAA 2FYOA 2II5A 3U9FA 1T1UA 1EADA 5T3EA 5KJSA 5FANA 1NOCB 1NM8A 1NDBA 1EACA 3B2SA 5KJVA 1NDIA 2RCUA 1DPDA 2H3UA 1L5AA 1Q23A 1T7NA 1T7OA 1S5OA 5DU9A 3U9BA 1XL8A 3L60A 2E1UA 4HVMA 1NDFA 2H3PA 1C4TA 2I9DA 1CIAA 5FALA 5DUAA 4N72A 1EABA 2RKVA 3FOTA 3FP0A 1XMCA 1Q6XA 4JN3A 2FW3A 2FY5A 4G22A 2FY2A 3MAEA 1DPBA 2XR7A 2II3A 2II4A 2DEBA 4JN5A 1DPCA 5KJWA 2IHWA 4EYWA 1XL7A 2E1VA 4EP9A 2XHGA 1PD5A 1CLAA 4G2MA 5KJTA 2FY4A 4KECA 4KE4A 3CLAA 3B30A 1SCZA 1EAEA 2CLAA 1XMDA 5KJUA
chains in the Genus database with same CATH topology

1NDFA 1T1UA 2DEBA 2JGPA 2H3PA 1Q9JA 2VSQA 5DUAA 4JN5A 5T3EA 2H3WA 4EYWA 4EP9A 1NM8A 3FOTA 3FP0A 2XHGA 2H4TA 1Q6XA 1NDBA 4JN3A 2FY4A 1NDIA 2RCUA 2FW3A 2FY5A 2H3UA 1L5AA 2FY3A 2FY2A 1T7QA 1T7NA 4EPHA 1T7OA 1S5OA 5DU9A 2FYOA 4HVMA
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 1NDF A;  1T1U A;  2DEB A;  2H3P A;  2H3W A;  4EYW A;  4EP9 A;  1NM8 A;  2H4T A;  1Q6X A;  1NDB A;  2FY4 A;  1NDI A;  2RCU A;  2FW3 A;  2FY5 A;  2H3U A;  2FY3 A;  2FY2 A;  1T7Q A;  1T7N A;  4EPH A;  1T7O A;  1S5O A;  2FYO A; 
#chains in the Genus database with same CATH topology
 2E1T A;  1QCA A;  2ZBA A;  2JGP A;  4CLA A;  2RKT A;  1Q9J A;  2VSQ A;  1EAF A;  2H3W A;  2H4T A;  2BGH A;  4G0B A;  1E2O A;  2FY3 A;  1T7Q A;  4EPH A;  1EAA A;  2FYO A;  2II5 A;  3U9F A;  1T1U A;  1EAD A;  5T3E A;  5KJS A;  5FAN A;  1NOC B;  1NM8 A;  1NDB A;  1EAC A;  3B2S A;  5KJV A;  1NDI A;  2RCU A;  1DPD A;  2H3U A;  1L5A A;  1Q23 A;  1T7N A;  1T7O A;  1S5O A;  5DU9 A;  3U9B A;  1XL8 A;  3L60 A;  2E1U A;  4HVM A;  1NDF A;  2H3P A;  1C4T A;  2I9D A;  1CIA A;  5FAL A;  5DUA A;  4N72 A;  1EAB A;  2RKV A;  3FOT A;  3FP0 A;  1XMC A;  1Q6X A;  4JN3 A;  2FW3 A;  2FY5 A;  4G22 A;  2FY2 A;  3MAE A;  1DPB A;  2XR7 A;  2II3 A;  2II4 A;  2DEB A;  4JN5 A;  1DPC A;  5KJW A;  2IHW A;  4EYW A;  1XL7 A;  2E1V A;  4EP9 A;  2XHG A;  1PD5 A;  1CLA A;  4G2M A;  5KJT A;  2FY4 A;  4KEC A;  4KE4 A;  3CLA A;  3B30 A;  1SCZ A;  1EAE A;  2CLA A;  1XMD A;  5KJU A; 
#chains in the Genus database with same CATH homology
 1NDF A;  1T1U A;  2DEB A;  2JGP A;  2H3P A;  1Q9J A;  2VSQ A;  5DUA A;  4JN5 A;  5T3E A;  2H3W A;  4EYW A;  4EP9 A;  1NM8 A;  3FOT A;  3FP0 A;  2XHG A;  2H4T A;  1Q6X A;  1NDB A;  4JN3 A;  2FY4 A;  1NDI A;  2RCU A;  2FW3 A;  2FY5 A;  2H3U A;  1L5A A;  2FY3 A;  2FY2 A;  1T7Q A;  1T7N A;  4EPH A;  1T7O A;  1S5O A;  5DU9 A;  2FYO A;  4HVM A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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1T1UA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations