2ISTA

Crystal structure of rlud from e. coli
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
324
structure length
321
Chain Sequence
AQRVQLTATVSENQLGQRLDQALAEMFPDYSRSRIKEWILDQRVLVNGKVCDKPKEKVLGGEQVAINAEIERFEPQDIPLDIVYEDEDIIIINKPRDLVVHPGAGNPDGTVLNALLHYYPPIADVPRAGIVHRLDKDTTGLMVVAKTVPAQTRLVESLQRREITREYEAVAIGHMTAGGTVDEPISRHPTKRTHMAVHPMGKPAVTHYRIMEHFRVHTRLRLRLETGRTHQIRVHMAHITHPLVGDPVYGGRPRPPKGASEAFISTLRKFDRQALHATMLRLYHPISGIEMEWHAPIPQDMVELIEVMRADFEEHKDEVDW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of RluD from E. coli
rcsb
molecule tags Isomerase
source organism Escherichia coli
molecule keywords Ribosomal large subunit pseudouridine synthase D
total genus 86
structure length 321
sequence length 324
ec nomenclature ec 5.4.99.23: 23S rRNA pseudouridine(1911/1915/1917) synthase.
pdb deposition date 2006-10-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00849 PseudoU_synth_2 RNA pseudouridylate synthase
A PF01479 S4 S4 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.290.10 Alpha Beta Roll Structural Genomics Hypothetical 15.5 Kd Protein In mrcA-pckA Intergenic Region; Chain A RNA-binding S4 domain 2istA01
3.30.2350.10 Alpha Beta 2-Layer Sandwich Pseudouridine synthase Pseudouridine synthase 2istA02
4JI2D 1N33D 4DUZD 3LWVA 4YY3D 1XMOD 4DV0D 4DR5D 3HAXA 2RFKA 1ZE1A 1XMQD 4X64D 2UXDD 1IBMD 4GKJD 1P9KA 1ZE2A 2E5LD 1KSVA 4LGTA 4X65D 4DUYD 4DR3D 4AQYD 2F4VD 4K0KD 1N36D 3HP7A 4LF7D 1H3EA 2I82A 4JV5D 3UAIA 5BR8D 2UUCD 4JYAD 1V9KA 3DH3A 1IBLD 3LWQA 2AB4A 4OUDA 4DV6D 4X66D 1XNQD 1SGVA 4DV4D 5LMND 1N34D 4B3SD 1K8WA 2VQED 4B3MD 1DM9A 4JI3D 5LMUD 1N32D 4JI0D 1JH3A 3KBGA 2EY4A 4KHPD 1V9FA 1FJGD 4OX9D 4DR7D 3HJYA 1HNZD 1R3EA 3LWOA 1ZL3A 1QYUA 4LFAD 3LWPA 1C06A 3T1YD 4JI5D 4LF5D 4LF9D 4DV3D 4X62D 4LF4D 2JANA 2UUAD 1FKAD 4YHHD 1VIOA 1HNXD 4LF6D 2UU9D 1I94D 1R3FA 3OTOD 5IWAD 2UXCD 3T1HD 4JI6D 1C05A 4DR6D 3LWRA 4DR2D 2HHHD 2VQFD 4JI1D 1H3FA 2K6PA 4DR1D 2AUSA 4B3RD 4LFBD 4DV7D 4LABA 4NXND 1KSKA 2UXBD 4DR4D 4JI7D 1XNRD 2ZM6D 2HVYA 4DV2D 1KSLA 1IBKD 3MQKA 2KTLA 1HNWD 4DV5D 1XPIA 2UUBD 1J5ED 4JI4D 4B3TD 1PRZA 2APOA 4NXMD 4LFCD 4GKKD 4LF8D 3HJWA 4JI8D 1HR0D 4DV1D 3U28A 2ISTA
chains in the Genus database with same CATH superfamily
4JI2D 1N33D 4DUZD 3LWVA 4YY3D 5FLXE 1SZWA 3ONHA 1XMOD 4DV0D 4DR5D 3HAXA 2RFKA 5A2QE 1ZE1A 1XMQD 4X64D 2UXDD 1IBMD 4GKJD 1Y8RB 1P9KA 1ZE2A 4NNJA 2E5LD 1KSVA 4LGTA 4X65D 4DUYD 4DR3D 4AQYD 2F4VD 4K0KD 1N36D 3HP7A 4LF7D 1H3EA 2I82A 4JV5D 3UAIA 1Z2ZA 5BR8D 2UUCD 4JYAD 1V9KA 3DH3A 1IBLD 1SB7A 3LWQA 2AB4A 4OUDA 4DV6D 4X66D 1XNQD 1SGVA 4DV4D 5LMND 1N34D 4B3SD 1SI7A 1K8WA 2VQED 4B3MD 1Y8XB 3ONGA 5IT9E 1DM9A 2NVUB 4JI3D 4W5VB 5LMUD 1N32D 4JI0D 1JH3A 5KNLA 3KBGA 2EY4A 1Y8QB 4KHPD 1V9FA 1FJGD 4II3A 4OX9D 4DR7D 3HJYA 1HNZD 1R3EA 3LWOA 3J80E 1ZL3A 1QYUA 5FQ2B 2ZTBA 4LFAD 3LWPA 1C06A 3T1YD 4JI5D 4II2A 4LF5D 4LF9D 4DV3D 4X62D 4LF4D 2JANA 2UUAD 1FKAD 4YHHD 3KYDB 2I1SA 1VIOA 1HNXD 4LF6D 2UU9D 1I94D 3CMMA 1R3FA 3OTOD 5IWAD 2UXCD 3JAME 3T1HD 4JI6D 1C05A 4DR6D 3LWRA 4DR2D 2HHHD 2VQFD 4JI1D 1H3FA 2K6PA 4DR1D 2AUSA 4B3RD 4LFBD 4DV7D 4LABA 4NXND 1KSKA 2UXBD 4DR4D 4JI7D 1XNRD 2ZM6D 5LL6S 2HVYA 2LQ7A 4DV2D 1KSLA 3FN1A 1IBKD 3KYCB 3MQKA 2KTLA 1HNWD 4DV5D 1XPIA 2UUBD 1J5ED 4JI4D 4B3TD 1PRZA 2APOA 4NXMD 3J81E 4LFCD 3J7AF 4GKKD 4LF8D 3HJWA 4JI8D 1HR0D 4DV1D 3U28A 2ISTA
chains in the Genus database with same CATH topology
4JI2D 1N33D 4DUZD 3LWVA 4YY3D 1SZWA 1XMOD 4DV0D 4DR5D 3HAXA 2RFKA 1ZE1A 1XMQD 4X64D 2UXDD 1IBMD 4GKJD 1P9KA 1ZE2A 2E5LD 1KSVA 4LGTA 4X65D 4DUYD 4DR3D 4AQYD 2F4VD 4K0KD 1N36D 3HP7A 4LF7D 1H3EA 2I82A 4JV5D 3UAIA 1Z2ZA 5BR8D 2UUCD 4JYAD 1V9KA 3DH3A 1IBLD 1SB7A 3LWQA 2AB4A 4OUDA 4DV6D 4X66D 1XNQD 1SGVA 4DV4D 5LMND 1N34D 4B3SD 1SI7A 1K8WA 2VQED 4B3MD 1DM9A 4JI3D 5LMUD 1N32D 4JI0D 1JH3A 3KBGA 2EY4A 4KHPD 1V9FA 1FJGD 4OX9D 4DR7D 3HJYA 1HNZD 1R3EA 3LWOA 1ZL3A 1QYUA 4LFAD 3LWPA 1C06A 3T1YD 4JI5D 4LF5D 4LF9D 4DV3D 4X62D 4LF4D 2JANA 2UUAD 1FKAD 4YHHD 1VIOA 1HNXD 4LF6D 2UU9D 1I94D 1R3FA 3OTOD 5IWAD 2UXCD 3T1HD 4JI6D 1C05A 4DR6D 3LWRA 4DR2D 2HHHD 2VQFD 4JI1D 1H3FA 2K6PA 4DR1D 2AUSA 4B3RD 4LFBD 4DV7D 4LABA 4NXND 1KSKA 2UXBD 4DR4D 4JI7D 1XNRD 2ZM6D 2HVYA 4DV2D 1KSLA 1IBKD 3MQKA 2KTLA 1HNWD 4DV5D 1XPIA 2UUBD 1J5ED 4JI4D 4B3TD 1PRZA 2APOA 4NXMD 4LFCD 4GKKD 4LF8D 3HJWA 4JI8D 1HR0D 4DV1D 3U28A 2ISTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4JI2 D;  1N33 D;  4DUZ D;  3LWV A;  4YY3 D;  1XMO D;  4DV0 D;  4DR5 D;  3HAX A;  2RFK A;  1ZE1 A;  1XMQ D;  4X64 D;  2UXD D;  1IBM D;  4GKJ D;  1P9K A;  1ZE2 A;  2E5L D;  1KSV A;  4LGT A;  4X65 D;  4DUY D;  4DR3 D;  4AQY D;  2F4V D;  4K0K D;  1N36 D;  3HP7 A;  4LF7 D;  1H3E A;  2I82 A;  4JV5 D;  3UAI A;  5BR8 D;  2UUC D;  4JYA D;  1V9K A;  3DH3 A;  1IBL D;  3LWQ A;  2AB4 A;  4OUD A;  4DV6 D;  4X66 D;  1XNQ D;  1SGV A;  4DV4 D;  5LMN D;  1N34 D;  4B3S D;  1K8W A;  2VQE D;  4B3M D;  1DM9 A;  4JI3 D;  5LMU D;  1N32 D;  4JI0 D;  1JH3 A;  3KBG A;  2EY4 A;  4KHP D;  1V9F A;  1FJG D;  4OX9 D;  4DR7 D;  3HJY A;  1HNZ D;  1R3E A;  3LWO A;  1ZL3 A;  1QYU A;  4LFA D;  3LWP A;  1C06 A;  3T1Y D;  4JI5 D;  4LF5 D;  4LF9 D;  4DV3 D;  4X62 D;  4LF4 D;  2JAN A;  2UUA D;  1FKA D;  4YHH D;  1VIO A;  1HNX D;  4LF6 D;  2UU9 D;  1I94 D;  1R3F A;  3OTO D;  5IWA D;  2UXC D;  3T1H D;  4JI6 D;  1C05 A;  4DR6 D;  3LWR A;  4DR2 D;  2HHH D;  2VQF D;  4JI1 D;  1H3F A;  2K6P A;  4DR1 D;  2AUS A;  4B3R D;  4LFB D;  4DV7 D;  4LAB A;  4NXN D;  1KSK A;  2UXB D;  4DR4 D;  4JI7 D;  1XNR D;  2ZM6 D;  2HVY A;  4DV2 D;  1KSL A;  1IBK D;  3MQK A;  2KTL A;  1HNW D;  4DV5 D;  1XPI A;  2UUB D;  1J5E D;  4JI4 D;  4B3T D;  1PRZ A;  2APO A;  4NXM D;  4LFC D;  4GKK D;  4LF8 D;  3HJW A;  4JI8 D;  1HR0 D;  4DV1 D;  3U28 A;  2IST A; 
#chains in the Genus database with same CATH topology
 4JI2 D;  1N33 D;  4DUZ D;  3LWV A;  4YY3 D;  5FLX E;  1SZW A;  3ONH A;  1XMO D;  4DV0 D;  4DR5 D;  3HAX A;  2RFK A;  5A2Q E;  1ZE1 A;  1XMQ D;  4X64 D;  2UXD D;  1IBM D;  4GKJ D;  1Y8R B;  1P9K A;  1ZE2 A;  4NNJ A;  2E5L D;  1KSV A;  4LGT A;  4X65 D;  4DUY D;  4DR3 D;  4AQY D;  2F4V D;  4K0K D;  1N36 D;  3HP7 A;  4LF7 D;  1H3E A;  2I82 A;  4JV5 D;  3UAI A;  1Z2Z A;  5BR8 D;  2UUC D;  4JYA D;  1V9K A;  3DH3 A;  1IBL D;  1SB7 A;  3LWQ A;  2AB4 A;  4OUD A;  4DV6 D;  4X66 D;  1XNQ D;  1SGV A;  4DV4 D;  5LMN D;  1N34 D;  4B3S D;  1SI7 A;  1K8W A;  2VQE D;  4B3M D;  1Y8X B;  3ONG A;  5IT9 E;  1DM9 A;  2NVU B;  4JI3 D;  4W5V B;  5LMU D;  1N32 D;  4JI0 D;  1JH3 A;  5KNL A;  3KBG A;  2EY4 A;  1Y8Q B;  4KHP D;  1V9F A;  1FJG D;  4II3 A;  4OX9 D;  4DR7 D;  3HJY A;  1HNZ D;  1R3E A;  3LWO A;  3J80 E;  1ZL3 A;  1QYU A;  5FQ2 B;  2ZTB A;  4LFA D;  3LWP A;  1C06 A;  3T1Y D;  4JI5 D;  4II2 A;  4LF5 D;  4LF9 D;  4DV3 D;  4X62 D;  4LF4 D;  2JAN A;  2UUA D;  1FKA D;  4YHH D;  3KYD B;  2I1S A;  1VIO A;  1HNX D;  4LF6 D;  2UU9 D;  1I94 D;  3CMM A;  1R3F A;  3OTO D;  5IWA D;  2UXC D;  3JAM E;  3T1H D;  4JI6 D;  1C05 A;  4DR6 D;  3LWR A;  4DR2 D;  2HHH D;  2VQF D;  4JI1 D;  1H3F A;  2K6P A;  4DR1 D;  2AUS A;  4B3R D;  4LFB D;  4DV7 D;  4LAB A;  4NXN D;  1KSK A;  2UXB D;  4DR4 D;  4JI7 D;  1XNR D;  2ZM6 D;  5LL6 S;  2HVY A;  2LQ7 A;  4DV2 D;  1KSL A;  3FN1 A;  1IBK D;  3KYC B;  3MQK A;  2KTL A;  1HNW D;  4DV5 D;  1XPI A;  2UUB D;  1J5E D;  4JI4 D;  4B3T D;  1PRZ A;  2APO A;  4NXM D;  3J81 E;  4LFC D;  3J7A F;  4GKK D;  4LF8 D;  3HJW A;  4JI8 D;  1HR0 D;  4DV1 D;  3U28 A;  2IST A; 
#chains in the Genus database with same CATH homology
 4JI2 D;  1N33 D;  4DUZ D;  3LWV A;  4YY3 D;  1SZW A;  1XMO D;  4DV0 D;  4DR5 D;  3HAX A;  2RFK A;  1ZE1 A;  1XMQ D;  4X64 D;  2UXD D;  1IBM D;  4GKJ D;  1P9K A;  1ZE2 A;  2E5L D;  1KSV A;  4LGT A;  4X65 D;  4DUY D;  4DR3 D;  4AQY D;  2F4V D;  4K0K D;  1N36 D;  3HP7 A;  4LF7 D;  1H3E A;  2I82 A;  4JV5 D;  3UAI A;  1Z2Z A;  5BR8 D;  2UUC D;  4JYA D;  1V9K A;  3DH3 A;  1IBL D;  1SB7 A;  3LWQ A;  2AB4 A;  4OUD A;  4DV6 D;  4X66 D;  1XNQ D;  1SGV A;  4DV4 D;  5LMN D;  1N34 D;  4B3S D;  1SI7 A;  1K8W A;  2VQE D;  4B3M D;  1DM9 A;  4JI3 D;  5LMU D;  1N32 D;  4JI0 D;  1JH3 A;  3KBG A;  2EY4 A;  4KHP D;  1V9F A;  1FJG D;  4OX9 D;  4DR7 D;  3HJY A;  1HNZ D;  1R3E A;  3LWO A;  1ZL3 A;  1QYU A;  4LFA D;  3LWP A;  1C06 A;  3T1Y D;  4JI5 D;  4LF5 D;  4LF9 D;  4DV3 D;  4X62 D;  4LF4 D;  2JAN A;  2UUA D;  1FKA D;  4YHH D;  1VIO A;  1HNX D;  4LF6 D;  2UU9 D;  1I94 D;  1R3F A;  3OTO D;  5IWA D;  2UXC D;  3T1H D;  4JI6 D;  1C05 A;  4DR6 D;  3LWR A;  4DR2 D;  2HHH D;  2VQF D;  4JI1 D;  1H3F A;  2K6P A;  4DR1 D;  2AUS A;  4B3R D;  4LFB D;  4DV7 D;  4LAB A;  4NXN D;  1KSK A;  2UXB D;  4DR4 D;  4JI7 D;  1XNR D;  2ZM6 D;  2HVY A;  4DV2 D;  1KSL A;  1IBK D;  3MQK A;  2KTL A;  1HNW D;  4DV5 D;  1XPI A;  2UUB D;  1J5E D;  4JI4 D;  4B3T D;  1PRZ A;  2APO A;  4NXM D;  4LFC D;  4GKK D;  4LF8 D;  3HJW A;  4JI8 D;  1HR0 D;  4DV1 D;  3U28 A;  2IST A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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