2ISTA

Crystal structure of rlud from e. coli
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
324
structure length
321
Chain Sequence
AQRVQLTATVSENQLGQRLDQALAEMFPDYSRSRIKEWILDQRVLVNGKVCDKPKEKVLGGEQVAINAEIERFEPQDIPLDIVYEDEDIIIINKPRDLVVHPGAGNPDGTVLNALLHYYPPIADVPRAGIVHRLDKDTTGLMVVAKTVPAQTRLVESLQRREITREYEAVAIGHMTAGGTVDEPISRHPTKRTHMAVHPMGKPAVTHYRIMEHFRVHTRLRLRLETGRTHQIRVHMAHITHPLVGDPVYGGRPRPPKGASEAFISTLRKFDRQALHATMLRLYHPISGIEMEWHAPIPQDMVELIEVMRADFEEHKDEVDW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of RluD from E. coli
rcsb
molecule tags Isomerase
source organism Escherichia coli
molecule keywords Ribosomal large subunit pseudouridine synthase D
total genus 86
structure length 321
sequence length 324
ec nomenclature ec 5.4.99.23: 23S rRNA pseudouridine(1911/1915/1917) synthase.
pdb deposition date 2006-10-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00849 PseudoU_synth_2 RNA pseudouridylate synthase
A PF01479 S4 S4 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.290.10 Alpha Beta Roll Structural Genomics Hypothetical 15.5 Kd Protein In mrcA-pckA Intergenic Region; Chain A RNA-binding S4 domain 2istA01
3.30.2350.10 Alpha Beta 2-Layer Sandwich Pseudouridine synthase Pseudouridine synthase 2istA02
1XNQD 4JI5D 4DR2D 2UUAD 4LF7D 4YY3D 2JANA 4DV0D 4LF9D 3LWVA 3HAXA 4DV2D 1HNWD 4DV7D 4JI1D 4B3SD 1P9KA 3T1YD 4DR5D 1HR0D 3T1HD 3HJYA 3OTOD 1N32D 2UUCD 1N33D 4JI6D 1KSVA 3LWPA 2AB4A 4JYAD 4LGTA 2I82A 4JI0D 2ISTA 2E5LD 4DR3D 3LWQA 1IBLD 1ZL3A 4X66D 1XMQD 2UUBD 4X64D 4DV3D 1I94D 4JI4D 4LF4D 4DR7D 1C05A 5BR8D 2HVYA 4LFCD 1JH3A 4DV4D 1XNRD 4X65D 2UXCD 3KBGA 4LF5D 1PRZA 4NXMD 1R3FA 4LF8D 1SGVA 5LMUD 4DV6D 4DUZD 4NXND 4JI7D 1C06A 5IWAD 4GKJD 1V9FA 1R3EA 4DUYD 2RFKA 4OX9D 4DR4D 1KSLA 1XPIA 3UAIA 3LWRA 2K6PA 1HNXD 2HHHD 4B3MD 2VQED 4GKKD 4DR6D 1QYUA 3HP7A 1DM9A 1FJGD 1IBKD 1ZE2A 1KSKA 1J5ED 1FKAD 4JI8D 3LWOA 2EY4A 4LABA 2KTLA 2F4VD 4JI3D 4LF6D 4DV5D 2UXDD 4YHHD 4LFAD 4B3RD 2UXBD 1N36D 3U28A 4DR1D 1N34D 3MQKA 2VQFD 4LFBD 1K8WA 1H3EA 2UU9D 3DH3A 4JI2D 1VIOA 4KHPD 1ZE1A 1IBMD 4AQYD 1V9KA 5LMND 2ZM6D 3HJWA 1HNZD 4X62D 2APOA 1XMOD 4B3TD 4DV1D 2AUSA 1H3FA 4OUDA 4K0KD 4JV5D
chains in the Genus database with same CATH superfamily
1XNQD 4JI5D 4DR2D 2UUAD 4LF7D 4W5VB 4YY3D 2JANA 4DV0D 4LF9D 3LWVA 3HAXA 4DV2D 1HNWD 4DV7D 4JI1D 4B3SD 1P9KA 3T1YD 4DR5D 1HR0D 3T1HD 3HJYA 3OTOD 1N32D 2UUCD 1N33D 4JI6D 1KSVA 3LWPA 2AB4A 4JYAD 4LGTA 3J7AF 2I82A 4JI0D 3ONGA 2ISTA 2E5LD 4DR3D 3LWQA 1IBLD 1ZL3A 4X66D 1XMQD 2UUBD 4X64D 4DV3D 1I94D 4JI4D 4LF4D 5A2QE 4DR7D 1C05A 5BR8D 2HVYA 4LFCD 1JH3A 4DV4D 2I1SA 1SZWA 1XNRD 4X65D 2UXCD 2LQ7A 3KBGA 4LF5D 1PRZA 4NXMD 1R3FA 4LF8D 1SGVA 5LMUD 4DV6D 4DUZD 4NXND 1Y8XB 4JI7D 1C06A 5IWAD 4GKJD 1V9FA 1R3EA 4DUYD 2RFKA 2ZTBA 4OX9D 4DR4D 1KSLA 1XPIA 3UAIA 3LWRA 1Y8RB 2K6PA 5FQ2B 5LL6S 1HNXD 2NVUB 2HHHD 4B3MD 2VQED 4GKKD 4DR6D 1QYUA 3HP7A 1DM9A 1FJGD 3CMMA 4NNJA 1IBKD 3KYDB 3JAME 1ZE2A 1KSKA 1J5ED 1FKAD 4JI8D 3LWOA 2EY4A 4LABA 2KTLA 2F4VD 1SI7A 4JI3D 4LF6D 4DV5D 2UXDD 1Y8QB 4II2A 4YHHD 4LFAD 4B3RD 4II3A 2UXBD 1SB7A 1N36D 3ONHA 4DR1D 3U28A 1N34D 3MQKA 2VQFD 5KNLA 4LFBD 1K8WA 1H3EA 2UU9D 3DH3A 3FN1A 5IT9E 4JI2D 1Z2ZA 1VIOA 4KHPD 3KYCB 3J80E 1ZE1A 1IBMD 3J81E 4AQYD 1V9KA 5LMND 5FLXE 2ZM6D 3HJWA 1HNZD 4X62D 2APOA 1XMOD 4B3TD 4DV1D 2AUSA 1H3FA 4OUDA 4K0KD 4JV5D
chains in the Genus database with same CATH topology
1XNQD 4JI5D 4DR2D 2UUAD 4LF7D 4YY3D 2JANA 4DV0D 4LF9D 3LWVA 3HAXA 4DV2D 1HNWD 4DV7D 4JI1D 4B3SD 1P9KA 3T1YD 4DR5D 1HR0D 3T1HD 3HJYA 3OTOD 1N32D 2UUCD 1N33D 4JI6D 1KSVA 3LWPA 2AB4A 4JYAD 4LGTA 2I82A 4JI0D 2ISTA 2E5LD 4DR3D 3LWQA 1IBLD 1ZL3A 4X66D 1XMQD 2UUBD 4X64D 4DV3D 1I94D 4JI4D 4LF4D 4DR7D 1C05A 5BR8D 2HVYA 4LFCD 1JH3A 4DV4D 1SZWA 1XNRD 4X65D 2UXCD 3KBGA 4LF5D 1PRZA 4NXMD 1R3FA 4LF8D 1SGVA 5LMUD 4DV6D 4DUZD 4NXND 4JI7D 1C06A 5IWAD 4GKJD 1V9FA 1R3EA 4DUYD 2RFKA 4OX9D 4DR4D 1KSLA 1XPIA 3UAIA 3LWRA 2K6PA 1HNXD 2HHHD 4B3MD 2VQED 4GKKD 4DR6D 1QYUA 3HP7A 1DM9A 1FJGD 1IBKD 1ZE2A 1KSKA 1J5ED 1FKAD 4JI8D 3LWOA 2EY4A 4LABA 2KTLA 2F4VD 1SI7A 4JI3D 4LF6D 4DV5D 2UXDD 4YHHD 4LFAD 4B3RD 2UXBD 1SB7A 1N36D 3U28A 4DR1D 1N34D 3MQKA 2VQFD 4LFBD 1K8WA 1H3EA 2UU9D 3DH3A 4JI2D 1Z2ZA 1VIOA 4KHPD 1ZE1A 1IBMD 4AQYD 1V9KA 5LMND 2ZM6D 3HJWA 1HNZD 4X62D 2APOA 1XMOD 4B3TD 4DV1D 2AUSA 1H3FA 4OUDA 4K0KD 4JV5D
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1XNQ D;  4JI5 D;  4DR2 D;  2UUA D;  4LF7 D;  4YY3 D;  2JAN A;  4DV0 D;  4LF9 D;  3LWV A;  3HAX A;  4DV2 D;  1HNW D;  4DV7 D;  4JI1 D;  4B3S D;  1P9K A;  3T1Y D;  4DR5 D;  1HR0 D;  3T1H D;  3HJY A;  3OTO D;  1N32 D;  2UUC D;  1N33 D;  4JI6 D;  1KSV A;  3LWP A;  2AB4 A;  4JYA D;  4LGT A;  2I82 A;  4JI0 D;  2IST A;  2E5L D;  4DR3 D;  3LWQ A;  1IBL D;  1ZL3 A;  4X66 D;  1XMQ D;  2UUB D;  4X64 D;  4DV3 D;  1I94 D;  4JI4 D;  4LF4 D;  4DR7 D;  1C05 A;  5BR8 D;  2HVY A;  4LFC D;  1JH3 A;  4DV4 D;  1XNR D;  4X65 D;  2UXC D;  3KBG A;  4LF5 D;  1PRZ A;  4NXM D;  1R3F A;  4LF8 D;  1SGV A;  5LMU D;  4DV6 D;  4DUZ D;  4NXN D;  4JI7 D;  1C06 A;  5IWA D;  4GKJ D;  1V9F A;  1R3E A;  4DUY D;  2RFK A;  4OX9 D;  4DR4 D;  1KSL A;  1XPI A;  3UAI A;  3LWR A;  2K6P A;  1HNX D;  2HHH D;  4B3M D;  2VQE D;  4GKK D;  4DR6 D;  1QYU A;  3HP7 A;  1DM9 A;  1FJG D;  1IBK D;  1ZE2 A;  1KSK A;  1J5E D;  1FKA D;  4JI8 D;  3LWO A;  2EY4 A;  4LAB A;  2KTL A;  2F4V D;  4JI3 D;  4LF6 D;  4DV5 D;  2UXD D;  4YHH D;  4LFA D;  4B3R D;  2UXB D;  1N36 D;  3U28 A;  4DR1 D;  1N34 D;  3MQK A;  2VQF D;  4LFB D;  1K8W A;  1H3E A;  2UU9 D;  3DH3 A;  4JI2 D;  1VIO A;  4KHP D;  1ZE1 A;  1IBM D;  4AQY D;  1V9K A;  5LMN D;  2ZM6 D;  3HJW A;  1HNZ D;  4X62 D;  2APO A;  1XMO D;  4B3T D;  4DV1 D;  2AUS A;  1H3F A;  4OUD A;  4K0K D;  4JV5 D; 
#chains in the Genus database with same CATH topology
 1XNQ D;  4JI5 D;  4DR2 D;  2UUA D;  4LF7 D;  4W5V B;  4YY3 D;  2JAN A;  4DV0 D;  4LF9 D;  3LWV A;  3HAX A;  4DV2 D;  1HNW D;  4DV7 D;  4JI1 D;  4B3S D;  1P9K A;  3T1Y D;  4DR5 D;  1HR0 D;  3T1H D;  3HJY A;  3OTO D;  1N32 D;  2UUC D;  1N33 D;  4JI6 D;  1KSV A;  3LWP A;  2AB4 A;  4JYA D;  4LGT A;  3J7A F;  2I82 A;  4JI0 D;  3ONG A;  2IST A;  2E5L D;  4DR3 D;  3LWQ A;  1IBL D;  1ZL3 A;  4X66 D;  1XMQ D;  2UUB D;  4X64 D;  4DV3 D;  1I94 D;  4JI4 D;  4LF4 D;  5A2Q E;  4DR7 D;  1C05 A;  5BR8 D;  2HVY A;  4LFC D;  1JH3 A;  4DV4 D;  2I1S A;  1SZW A;  1XNR D;  4X65 D;  2UXC D;  2LQ7 A;  3KBG A;  4LF5 D;  1PRZ A;  4NXM D;  1R3F A;  4LF8 D;  1SGV A;  5LMU D;  4DV6 D;  4DUZ D;  4NXN D;  1Y8X B;  4JI7 D;  1C06 A;  5IWA D;  4GKJ D;  1V9F A;  1R3E A;  4DUY D;  2RFK A;  2ZTB A;  4OX9 D;  4DR4 D;  1KSL A;  1XPI A;  3UAI A;  3LWR A;  1Y8R B;  2K6P A;  5FQ2 B;  5LL6 S;  1HNX D;  2NVU B;  2HHH D;  4B3M D;  2VQE D;  4GKK D;  4DR6 D;  1QYU A;  3HP7 A;  1DM9 A;  1FJG D;  3CMM A;  4NNJ A;  1IBK D;  3KYD B;  3JAM E;  1ZE2 A;  1KSK A;  1J5E D;  1FKA D;  4JI8 D;  3LWO A;  2EY4 A;  4LAB A;  2KTL A;  2F4V D;  1SI7 A;  4JI3 D;  4LF6 D;  4DV5 D;  2UXD D;  1Y8Q B;  4II2 A;  4YHH D;  4LFA D;  4B3R D;  4II3 A;  2UXB D;  1SB7 A;  1N36 D;  3ONH A;  4DR1 D;  3U28 A;  1N34 D;  3MQK A;  2VQF D;  5KNL A;  4LFB D;  1K8W A;  1H3E A;  2UU9 D;  3DH3 A;  3FN1 A;  5IT9 E;  4JI2 D;  1Z2Z A;  1VIO A;  4KHP D;  3KYC B;  3J80 E;  1ZE1 A;  1IBM D;  3J81 E;  4AQY D;  1V9K A;  5LMN D;  5FLX E;  2ZM6 D;  3HJW A;  1HNZ D;  4X62 D;  2APO A;  1XMO D;  4B3T D;  4DV1 D;  2AUS A;  1H3F A;  4OUD A;  4K0K D;  4JV5 D; 
#chains in the Genus database with same CATH homology
 1XNQ D;  4JI5 D;  4DR2 D;  2UUA D;  4LF7 D;  4YY3 D;  2JAN A;  4DV0 D;  4LF9 D;  3LWV A;  3HAX A;  4DV2 D;  1HNW D;  4DV7 D;  4JI1 D;  4B3S D;  1P9K A;  3T1Y D;  4DR5 D;  1HR0 D;  3T1H D;  3HJY A;  3OTO D;  1N32 D;  2UUC D;  1N33 D;  4JI6 D;  1KSV A;  3LWP A;  2AB4 A;  4JYA D;  4LGT A;  2I82 A;  4JI0 D;  2IST A;  2E5L D;  4DR3 D;  3LWQ A;  1IBL D;  1ZL3 A;  4X66 D;  1XMQ D;  2UUB D;  4X64 D;  4DV3 D;  1I94 D;  4JI4 D;  4LF4 D;  4DR7 D;  1C05 A;  5BR8 D;  2HVY A;  4LFC D;  1JH3 A;  4DV4 D;  1SZW A;  1XNR D;  4X65 D;  2UXC D;  3KBG A;  4LF5 D;  1PRZ A;  4NXM D;  1R3F A;  4LF8 D;  1SGV A;  5LMU D;  4DV6 D;  4DUZ D;  4NXN D;  4JI7 D;  1C06 A;  5IWA D;  4GKJ D;  1V9F A;  1R3E A;  4DUY D;  2RFK A;  4OX9 D;  4DR4 D;  1KSL A;  1XPI A;  3UAI A;  3LWR A;  2K6P A;  1HNX D;  2HHH D;  4B3M D;  2VQE D;  4GKK D;  4DR6 D;  1QYU A;  3HP7 A;  1DM9 A;  1FJG D;  1IBK D;  1ZE2 A;  1KSK A;  1J5E D;  1FKA D;  4JI8 D;  3LWO A;  2EY4 A;  4LAB A;  2KTL A;  2F4V D;  1SI7 A;  4JI3 D;  4LF6 D;  4DV5 D;  2UXD D;  4YHH D;  4LFA D;  4B3R D;  2UXB D;  1SB7 A;  1N36 D;  3U28 A;  4DR1 D;  1N34 D;  3MQK A;  2VQF D;  4LFB D;  1K8W A;  1H3E A;  2UU9 D;  3DH3 A;  4JI2 D;  1Z2Z A;  1VIO A;  4KHP D;  1ZE1 A;  1IBM D;  4AQY D;  1V9K A;  5LMN D;  2ZM6 D;  3HJW A;  1HNZ D;  4X62 D;  2APO A;  1XMO D;  4B3T D;  4DV1 D;  2AUS A;  1H3F A;  4OUD A;  4K0K D;  4JV5 D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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