2W54B

Crystal structure of xanthine dehydrogenase from rhodobacter capsulatus in complex with bound inhibitor pterin-6-aldehyde
Total Genus 249
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
249
sequence length
776
structure length
760
Chain Sequence
SVGKPLPHDSARAHVTGQARYLDDLPCPANTLHLAFGLSTEASAAITGLDLEPVRESPGVIAVFTAADLPHDNDASPAPSPEPVLATGEVHFVGQPIFLVAATSHRAARIAARKARITYAPRPAILTLDQALAADSRFEGGPVIWARGDVETALAGAAHLAEGCFEIGGQEHFYLEGQAALALPAEGGVVIHCSSQHPSEIQHKVAHALGLAFHDVRVEMRRMGGGFGGKESQGNHLAIACAVAARATGRPCKMRYDRDDDMVITGKRHDFRIRYRIGADASGKLLGADFVHLARCGWSADLSLPVCDRAMLHADGSYFVPALRIESHRLRTNTQSNTAFRGFGGPQGALGMERAIEHLARGMGRDPAELRALNFYDPPEKKTQTTHYGQEVADCVLGELVTRLQKSANFTTRRAEIAAWNSTNRTLARGIALSPVKFGISFTLTHLNQAGALVQIYTDGSVALNHGGTEMGQGLHAKMVQVAAAVLGIDPVQVRITATDTSKVPNTSATAASSGADMNGMAVKDACETLRGRLAGFVAAREGCAARDVIFDAGQVQASGKSWRFAEIVAAAYMARISLSATGFYATPKLSWDRLRGQGRPFLYFAYGAAITEVVIDRLTGENRILRTDILHDAGASLNPALDIGQIEGAYVQGAGWLTTEELVWDHCGRLMTHAPSTYKIPAFSDRPRIFNVALWDQPNREETIFRSKAVGEPPFLLGISAFLALHDACAACGPHWPDLQAPATPEAVLAAVRRAEGRA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Mechanism of Substrate and Inhibitor Binding of Rhodobacter Capsulatus Xanthine Dehydrogenase.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Rhodobacter capsulatus
molecule keywords XANTHINE DEHYDROGENASE
total genus 249
structure length 760
sequence length 776
chains with identical sequence D, F, H
ec nomenclature ec 1.1.1.204: Transferred entry: 1.17.1.4.
pdb deposition date 2008-12-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF01315 Ald_Xan_dh_C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain
B PF02738 Ald_Xan_dh_C2 Molybdopterin-binding domain of aldehyde dehydrogenase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.365.10 Alpha Beta 2-Layer Sandwich Aldehyde Oxidoreductase; domain 4 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain 2w54B05
3.30.365.10 Alpha Beta 2-Layer Sandwich Aldehyde Oxidoreductase; domain 4 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain 2w54B02
3.30.365.10 Alpha Beta 2-Layer Sandwich Aldehyde Oxidoreductase; domain 4 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain 2w54B04
3.30.365.10 Alpha Beta 2-Layer Sandwich Aldehyde Oxidoreductase; domain 4 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain 2w54B03
3.90.1170.50 Alpha Beta Alpha-Beta Complex Aldehyde Oxidoreductase; domain 3 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead 2w54B01
4C80A 2W3SB 1N62B 3AMZA 4USAA 2E3TA 4C7ZA 1FFUB 3FC4A 2W3RB 3AM9A 1WYGA 1FIQC 1ZXIB 3L4PA 3FAHA 3SR6C 1N60B 1V97A 3NVYC 1N5WB 3HRDB 3NVVC 4C7YA 4ZOHA 1FO4A 1SIJA 3NVWC 1VLBA 3NVZC 1N61B 2W55B 1JROB 3B9JC 3EUB4 1DGJA 1RM6A 1VDVA 1SB3A 3NS1C 1N63B 3NRZC 4US8A 1FFVB 4US9A 2W54B 3ETRC 1N5XA 1JRPB 3HRDA 3AN1A
chains in the Genus database with same CATH superfamily
1OTPA 5DM6J 1K73J 4IOCJ 3GNNA 1FFUB 1QPRA 3WO1A 3AM9A 1WYGA 1VQNH 3SR6C 3VMMA 4U67J 4WFAJ 1V97A 4GA4A 1M1KJ 2B7QA 3HRDB 5GAEN 2B7NA 4C7YA 3J7ZM 3PIPJ 1N8RJ 2DSJA 1VQ4H 3C2FA 3CCLH 1S72H 2ZJQJ 2W55B 2WK5A 3CF5J 1DGJA 1SB3A 3C2EA 4YEKA 4UY8M 1YTKA 4WF9J 1K9MJ 2QA4H 1YI2H 4IOAJ 5AYXA 4WFNJ 1K8AJ 1FM0E 5HULA 2Q5WE 3CC2H 2PA2A 1JJ2H 5GAHN 4USAA 3CD6H 4C7ZA 1O4UA 2B7PA 1X1OA 1KQSH 4KWWA 1ZXIB 3I56H 1N60B 2OMDA 4GA6A 4KWVA 3PIOJ 2ZJPJ 5JVGJ 5EY3A 4ZOHA 1T3QB 1FO4A 1W2BH 2WK6A 1SIJA 3WNZA 3NVWC 1JROB 3B9JC 3CXCH 1RM6A 2WP4A 1YTDA 3G6EH 4IO9J 1VQMH 3CPWH 4WCEJ 3CCJH 3CCRH 5AN9F 1QPQA 2W54B 1WKIA 3EUB4 1N5XA 3FAHA 3AN1A 4C80A 3RPFA 5MLCO 1VQ9H 1QPNA 1YTEA 2E3TA 1FMAE 3FC4A 1VQ7H 3CC7H 1NVIE 2OTLH 4I9AA 1FIQC 3L4PA 3H5QA 1YIJH 5GADN 1VQOH 2TPTA 1N5WB 2OTJH 1VQ8H 1QVFH 1KD1J 4LHMA 1Q81J 3G71H 1M90J 5DM7J 4X46A 1VLBA 3C2OA 3L0GA 3C2VA 3CCEH 2I1OA 2ZJRJ 3TQVA 1VDVA 1BRWA 1QAPA 5H1SO 1N63B 3NRZC 4YYYA 3OW2H 2J0FA 3CMAH 1Q7YJ 1NJIJ 4US9A 4AP8A 5EP8A 5JVHJ 3CMEH 1KC8J 3ETRC 4XR5A 3HRDA 2JBMA 5MPOC 1YITH 5HL7J 1YJWH 1YJ9H 2W3SB 1N62B 3AMZA 1Q82J 1VQ6H 3C2RA 2W3RB 3CCUH 4EADA 1VQKH 1AZYA 3G4SH 1UOUA 3NVYC 3BIIE 4EAFA 2QEXH 3CCMH 5AYZA 4GA5A 3NVVC 5AYYA 3PAJA 5HUOA 2QIEA 1Y69K 3DLLJ 3NVZC 1N61B 5GAGN 1NVJA 5HUPA 3NS1C 1QPOA 4WFBJ 3I55H 4US8A 1FFVB 2I14A 1Q86J 1QVGH 3CC4H 3WO0A 1YJNH 1YHQH 1VQLH 3CCQH 1VQPH 3CCSH 1JRPB 1VQ5H 3CCVH
chains in the Genus database with same CATH topology
4C80A 2W3SB 1N62B 3AMZA 4USAA 2E3TA 4C7ZA 1FFUB 3FC4A 2W3RB 3AM9A 1WYGA 1FIQC 1ZXIB 3L4PA 3FAHA 3SR6C 1N60B 1V97A 3NVYC 1N5WB 3HRDB 3NVVC 4C7YA 4ZOHA 1FO4A 1SIJA 3NVWC 1VLBA 3NVZC 1N61B 2W55B 1JROB 3B9JC 3EUB4 1DGJA 1RM6A 1VDVA 1SB3A 3NS1C 1N63B 3NRZC 4US8A 1FFVB 4US9A 2W54B 3ETRC 1N5XA 1JRPB 3HRDA 3AN1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4C80 A;  2W3S B;  1N62 B;  3AMZ A;  4USA A;  2E3T A;  4C7Z A;  1FFU B;  3FC4 A;  2W3R B;  3AM9 A;  1WYG A;  1FIQ C;  1ZXI B;  3L4P A;  3FAH A;  3SR6 C;  1N60 B;  1V97 A;  3NVY C;  1N5W B;  3HRD B;  3NVV C;  4C7Y A;  4ZOH A;  1FO4 A;  1SIJ A;  3NVW C;  1VLB A;  3NVZ C;  1N61 B;  2W55 B;  1JRO B;  3B9J C;  3EUB 4;  1DGJ A;  1RM6 A;  1VDV A;  1SB3 A;  3NS1 C;  1N63 B;  3NRZ C;  4US8 A;  1FFV B;  4US9 A;  2W54 B;  3ETR C;  1N5X A;  1JRP B;  3HRD A;  3AN1 A; 
#chains in the Genus database with same CATH topology
 1OTP A;  5DM6 J;  1K73 J;  4IOC J;  3GNN A;  1FFU B;  1QPR A;  3WO1 A;  3AM9 A;  1WYG A;  1VQN H;  3SR6 C;  3VMM A;  4U67 J;  4WFA J;  1V97 A;  4GA4 A;  1M1K J;  2B7Q A;  3HRD B;  5GAE N;  2B7N A;  4C7Y A;  3J7Z M;  3PIP J;  1N8R J;  2DSJ A;  1VQ4 H;  3C2F A;  3CCL H;  1S72 H;  2ZJQ J;  2W55 B;  2WK5 A;  3CF5 J;  1DGJ A;  1SB3 A;  3C2E A;  4YEK A;  4UY8 M;  1YTK A;  4WF9 J;  1K9M J;  2QA4 H;  1YI2 H;  4IOA J;  5AYX A;  4WFN J;  1K8A J;  1FM0 E;  5HUL A;  2Q5W E;  3CC2 H;  2PA2 A;  1JJ2 H;  5GAH N;  4USA A;  3CD6 H;  4C7Z A;  1O4U A;  2B7P A;  1X1O A;  1KQS H;  4KWW A;  1ZXI B;  3I56 H;  1N60 B;  2OMD A;  4GA6 A;  4KWV A;  3PIO J;  2ZJP J;  5JVG J;  5EY3 A;  4ZOH A;  1T3Q B;  1FO4 A;  1W2B H;  2WK6 A;  1SIJ A;  3WNZ A;  3NVW C;  1JRO B;  3B9J C;  3CXC H;  1RM6 A;  2WP4 A;  1YTD A;  3G6E H;  4IO9 J;  1VQM H;  3CPW H;  4WCE J;  3CCJ H;  3CCR H;  5AN9 F;  1QPQ A;  2W54 B;  1WKI A;  3EUB 4;  1N5X A;  3FAH A;  3AN1 A;  4C80 A;  3RPF A;  5MLC O;  1VQ9 H;  1QPN A;  1YTE A;  2E3T A;  1FMA E;  3FC4 A;  1VQ7 H;  3CC7 H;  1NVI E;  2OTL H;  4I9A A;  1FIQ C;  3L4P A;  3H5Q A;  1YIJ H;  5GAD N;  1VQO H;  2TPT A;  1N5W B;  2OTJ H;  1VQ8 H;  1QVF H;  1KD1 J;  4LHM A;  1Q81 J;  3G71 H;  1M90 J;  5DM7 J;  4X46 A;  1VLB A;  3C2O A;  3L0G A;  3C2V A;  3CCE H;  2I1O A;  2ZJR J;  3TQV A;  1VDV A;  1BRW A;  1QAP A;  5H1S O;  1N63 B;  3NRZ C;  4YYY A;  3OW2 H;  2J0F A;  3CMA H;  1Q7Y J;  1NJI J;  4US9 A;  4AP8 A;  5EP8 A;  5JVH J;  3CME H;  1KC8 J;  3ETR C;  4XR5 A;  3HRD A;  2JBM A;  5MPO C;  1YIT H;  5HL7 J;  1YJW H;  1YJ9 H;  2W3S B;  1N62 B;  3AMZ A;  1Q82 J;  1VQ6 H;  3C2R A;  2W3R B;  3CCU H;  4EAD A;  1VQK H;  1AZY A;  3G4S H;  1UOU A;  3NVY C;  3BII E;  4EAF A;  2QEX H;  3CCM H;  5AYZ A;  4GA5 A;  3NVV C;  5AYY A;  3PAJ A;  5HUO A;  2QIE A;  1Y69 K;  3DLL J;  3NVZ C;  1N61 B;  5GAG N;  1NVJ A;  5HUP A;  3NS1 C;  1QPO A;  4WFB J;  3I55 H;  4US8 A;  1FFV B;  2I14 A;  1Q86 J;  1QVG H;  3CC4 H;  3WO0 A;  1YJN H;  1YHQ H;  1VQL H;  3CCQ H;  1VQP H;  3CCS H;  1JRP B;  1VQ5 H;  3CCV H; 
#chains in the Genus database with same CATH homology
 4C80 A;  2W3S B;  1N62 B;  3AMZ A;  4USA A;  2E3T A;  4C7Z A;  1FFU B;  3FC4 A;  2W3R B;  3AM9 A;  1WYG A;  1FIQ C;  1ZXI B;  3L4P A;  3FAH A;  3SR6 C;  1N60 B;  1V97 A;  3NVY C;  1N5W B;  3HRD B;  3NVV C;  4C7Y A;  4ZOH A;  1FO4 A;  1SIJ A;  3NVW C;  1VLB A;  3NVZ C;  1N61 B;  2W55 B;  1JRO B;  3B9J C;  3EUB 4;  1DGJ A;  1RM6 A;  1VDV A;  1SB3 A;  3NS1 C;  1N63 B;  3NRZ C;  4US8 A;  1FFV B;  4US9 A;  2W54 B;  3ETR C;  1N5X A;  1JRP B;  3HRD A;  3AN1 A; 
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similar chains in the pdb database (?% sequence similarity)

 
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