2XHGA

Crystal structure of the epimerization domain from the initiation module of tyrocidine biosynthesis
Total Genus 161
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
161
sequence length
457
structure length
457
Chain Sequence
KSDQGIIAGNVPLTPIQKWFFGKNFTNTGHWNQSSVLYRPEGFDPKVIQSVMDKIIEHHDALRMVYQHENGNVVQHNRGLGGQLYDFFSYNLTAQPDVQQAIEAETQRLHSSMNLQEGPLVKVALFQTLHGDHLFLAIHHLVVDGISWRILFEDLATGYAQALAGQAISLPEKTDSFQSWSQWLQEYANEADLLSEIPYWESLESQAKNVSLPKDYEVTDCKQKSVRNMRIRLHPEETEQLLKHANQAYQTEINDLLLAALGLAFAEWSKLAQIVIHLEGHGREDIIEQANVARTVGWFTSQYPVLLDLKQTAPLSDYIKLTKENMRKIPRKGIGYDILKHVTLPENRGSLSFRVQPEVTFNYLGQFDADMRTELFTRSPYSGGNTLGADGKNNLSPESEVYTALNITGLIEGGELVLTFSYSSEQYREESIQQLSQSYQKHLLAIIAHCLQSHHHH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the Epimerization Domain of Tyrocidine Synthetase A
pubmed doi rcsb
molecule tags Isomerase
source organism Brevibacillus brevis
molecule keywords TYROCIDINE SYNTHETASE A
total genus 161
structure length 457
sequence length 457
ec nomenclature
pdb deposition date 2010-06-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00668 Condensation Condensation domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.559.10 Alpha Beta 2-Layer Sandwich Chloramphenicol Acetyltransferase Chloramphenicol acetyltransferase-like domain 2xhgA01
3.30.559.30 Alpha Beta 2-Layer Sandwich Chloramphenicol Acetyltransferase Chloramphenicol Acetyltransferase 2xhgA02
3MAEA 2BGHA 3L60A 1QCAA 1L5AA 4HVMA 4KECA 1PD5A 3U9FA 2IHWA 1Q9JA 1EACA 2II4A 1EAAA 4JN3A 1DPCA 2E1VA 2ZBAA 1DPBA 1EADA 3B30A 2JGPA 4JN5A 5KJTA 4G2MA 1Q23A 2E1TA 5KJUA 5KJSA 1XMCA 5DU9A 1XL7A 2XHGA 2VSQA 1EAEA 2E1UA 2XR7A 5FALA 2I9DA 1XL8A 1SCZA 3FP0A 2RKTA 4KE4A 1CIAA 3B2SA 1EABA 3U9BA 4N72A 1NOCB 1C4TA 1XMDA 4G0BA 5T3EA 5FANA 2RKVA 5DUAA 1DPDA 4CLAA 5KJVA 2CLAA 3FOTA 2II3A 2II5A 1CLAA 3CLAA 4G22A 1EAFA 5KJWA 1E2OA
chains in the Genus database with same CATH superfamily
3L60A 2DEBA 1QCAA 4KECA 1Q9JA 2II4A 1DPCA 2E1VA 3B30A 5KJSA 1XMCA 5FALA 2RCUA 2FY4A 4KE4A 3U9BA 2H3WA 1NOCB 2FY3A 2CLAA 3FOTA 2II5A 3CLAA 1T1UA 4EP9A 2FYOA 5KJTA 1Q23A 2XHGA 2I9DA 2RKTA 1CIAA 3B2SA 4N72A 1C4TA 5T3EA 4CLAA 1NDBA 1CLAA 4G22A 1EAFA 2BGHA 1L5AA 2H3UA 1PD5A 3U9FA 2IHWA 1EACA 1NDIA 2ZBAA 2JGPA 4JN5A 2H3PA 2E1TA 2XR7A 1S5OA 1SCZA 3FP0A 1EABA 1NM8A 1XMDA 2FW3A 5DUAA 2H4TA 2FY5A 1NDFA 2II3A 2FY2A 1Q6XA 1E2OA 1T7QA 3MAEA 4HVMA 1T7NA 1EAAA 4JN3A 1DPBA 1EADA 4G2MA 5KJUA 5DU9A 1XL7A 2VSQA 1T7OA 1EAEA 2E1UA 1XL8A 4G0BA 5FANA 2RKVA 5KJVA 1DPDA 4EYWA 4EPHA 5KJWA
chains in the Genus database with same CATH topology
3L60A 2DEBA 1QCAA 4KECA 1Q9JA 2II4A 1DPCA 2E1VA 3B30A 5KJSA 1XMCA 5FALA 2RCUA 2FY4A 4KE4A 3U9BA 2H3WA 1NOCB 2FY3A 2CLAA 3FOTA 2II5A 3CLAA 1T1UA 4EP9A 2FYOA 5KJTA 1Q23A 2XHGA 2I9DA 2RKTA 1CIAA 3B2SA 4N72A 1C4TA 5T3EA 4CLAA 1NDBA 1CLAA 4G22A 1EAFA 2BGHA 1L5AA 2H3UA 1PD5A 3U9FA 2IHWA 1EACA 1NDIA 2ZBAA 2JGPA 4JN5A 2H3PA 2E1TA 2XR7A 1S5OA 1SCZA 3FP0A 1EABA 1NM8A 1XMDA 2FW3A 5DUAA 2H4TA 2FY5A 2II3A 1NDFA 1Q6XA 2FY2A 1E2OA 1T7QA 3MAEA 4HVMA 1T7NA 1EAAA 4JN3A 1DPBA 1EADA 4G2MA 5KJUA 5DU9A 1XL7A 2VSQA 1T7OA 1EAEA 2E1UA 1XL8A 4G0BA 5FANA 2RKVA 5KJVA 1DPDA 4EYWA 4EPHA 5KJWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3MAE A;  2BGH A;  3L60 A;  1QCA A;  1L5A A;  4HVM A;  4KEC A;  1PD5 A;  3U9F A;  2IHW A;  1Q9J A;  1EAC A;  2II4 A;  1EAA A;  4JN3 A;  1DPC A;  2E1V A;  2ZBA A;  1DPB A;  1EAD A;  3B30 A;  2JGP A;  4JN5 A;  5KJT A;  4G2M A;  1Q23 A;  2E1T A;  5KJU A;  5KJS A;  1XMC A;  5DU9 A;  1XL7 A;  2XHG A;  2VSQ A;  1EAE A;  2E1U A;  2XR7 A;  5FAL A;  2I9D A;  1XL8 A;  1SCZ A;  3FP0 A;  2RKT A;  4KE4 A;  1CIA A;  3B2S A;  1EAB A;  3U9B A;  4N72 A;  1NOC B;  1C4T A;  1XMD A;  4G0B A;  5T3E A;  5FAN A;  2RKV A;  5DUA A;  1DPD A;  4CLA A;  5KJV A;  2CLA A;  3FOT A;  2II3 A;  2II5 A;  1CLA A;  3CLA A;  4G22 A;  1EAF A;  5KJW A;  1E2O A; 
#chains in the Genus database with same CATH topology
 3L60 A;  2DEB A;  1QCA A;  4KEC A;  1Q9J A;  2II4 A;  1DPC A;  2E1V A;  3B30 A;  5KJS A;  1XMC A;  5FAL A;  2RCU A;  2FY4 A;  4KE4 A;  3U9B A;  2H3W A;  1NOC B;  2FY3 A;  2CLA A;  3FOT A;  2II5 A;  3CLA A;  1T1U A;  4EP9 A;  2FYO A;  5KJT A;  1Q23 A;  2XHG A;  2I9D A;  2RKT A;  1CIA A;  3B2S A;  4N72 A;  1C4T A;  5T3E A;  4CLA A;  1NDB A;  1CLA A;  4G22 A;  1EAF A;  2BGH A;  1L5A A;  2H3U A;  1PD5 A;  3U9F A;  2IHW A;  1EAC A;  1NDI A;  2ZBA A;  2JGP A;  4JN5 A;  2H3P A;  2E1T A;  2XR7 A;  1S5O A;  1SCZ A;  3FP0 A;  1EAB A;  1NM8 A;  1XMD A;  2FW3 A;  5DUA A;  2H4T A;  2FY5 A;  1NDF A;  2II3 A;  2FY2 A;  1Q6X A;  1E2O A;  1T7Q A;  3MAE A;  4HVM A;  1T7N A;  1EAA A;  4JN3 A;  1DPB A;  1EAD A;  4G2M A;  5KJU A;  5DU9 A;  1XL7 A;  2VSQ A;  1T7O A;  1EAE A;  2E1U A;  1XL8 A;  4G0B A;  5FAN A;  2RKV A;  5KJV A;  1DPD A;  4EYW A;  4EPH A;  5KJW A; 
#chains in the Genus database with same CATH homology
 3L60 A;  2DEB A;  1QCA A;  4KEC A;  1Q9J A;  2II4 A;  1DPC A;  2E1V A;  3B30 A;  5KJS A;  1XMC A;  5FAL A;  2RCU A;  2FY4 A;  4KE4 A;  3U9B A;  2H3W A;  1NOC B;  2FY3 A;  2CLA A;  3FOT A;  2II5 A;  3CLA A;  1T1U A;  4EP9 A;  2FYO A;  5KJT A;  1Q23 A;  2XHG A;  2I9D A;  2RKT A;  1CIA A;  3B2S A;  4N72 A;  1C4T A;  5T3E A;  4CLA A;  1NDB A;  1CLA A;  4G22 A;  1EAF A;  2BGH A;  1L5A A;  2H3U A;  1PD5 A;  3U9F A;  2IHW A;  1EAC A;  1NDI A;  2ZBA A;  2JGP A;  4JN5 A;  2H3P A;  2E1T A;  2XR7 A;  1S5O A;  1SCZ A;  3FP0 A;  1EAB A;  1NM8 A;  1XMD A;  2FW3 A;  5DUA A;  2H4T A;  2FY5 A;  2II3 A;  1NDF A;  1Q6X A;  2FY2 A;  1E2O A;  1T7Q A;  3MAE A;  4HVM A;  1T7N A;  1EAA A;  4JN3 A;  1DPB A;  1EAD A;  4G2M A;  5KJU A;  5DU9 A;  1XL7 A;  2VSQ A;  1T7O A;  1EAE A;  2E1U A;  1XL8 A;  4G0B A;  5FAN A;  2RKV A;  5KJV A;  1DPD A;  4EYW A;  4EPH A;  5KJW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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