3L60A

Crystal structure of branched-chain alpha-keto acid dehydrogenase subunit e2 from mycobacterium tuberculosis
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
229
structure length
229
Chain Sequence
PDVRPVHGVHARMAEKMTLSHKEIPTAKASVEVICAELLRLRDRFVSAAPEITPFALTLRLLVIALKHNVILNSTWVDSGEGPQVHVHRGVHLGFGAATERGLLVPVVTDAQDKNTRELASRVAELITGAREGTLTPAELRGSTFTVSNFGALGVDDGVPVINHPEAAILGLGAIKPRPVVVGGEVVARPTMTLTCVFDHRVVDGAQVAQFMCELRDLIESPETALLDL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of Branched-Chain Alpha-Keto Acid Dehydrogenase Subunit E2 from Mycobacterium Tuberculosis
rcsb
molecule tags Oxidoreductase
source organism Mycobacterium tuberculosis
molecule keywords BRANCHED-CHAIN ALPHA-KETO ACID DEHYDROGENASE
total genus 69
structure length 229
sequence length 229
ec nomenclature ec 2.3.1.168: Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase.
pdb deposition date 2009-12-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00198 2-oxoacid_dh 2-oxoacid dehydrogenases acyltransferase (catalytic domain)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.559.10 Alpha Beta 2-Layer Sandwich Chloramphenicol Acetyltransferase Chloramphenicol acetyltransferase-like domain 3l60A01
2E1UA 1DPDA 1XMDA 3CLAA 5FALA 2I9DA 5KJUA 3MAEA 1L5AA 1EADA 2BGHA 4CLAA 1NOCB 2RKTA 5DU9A 3FOTA 1DPCA 1XL8A 2CLAA 1QCAA 1E2OA 1DPBA 1SCZA 2E1TA 2IHWA 3L60A 4G2MA 4KE4A 5FANA 1EAAA 5DUAA 2JGPA 5KJWA 5KJVA 2RKVA 2ZBAA 1Q9JA 3U9BA 1EABA 2E1VA 3B2SA 3U9FA 5KJTA 4G0BA 5KJSA 1PD5A 1XL7A 1CLAA 1XMCA 4HVMA 3FP0A 2II3A 2VSQA 4JN5A 1C4TA 4KECA 4N72A 5T3EA 1EAEA 2XR7A 4G22A 1CIAA 1EACA 2II5A 2II4A 4JN3A 3B30A 1Q23A 2XHGA 1EAFA
chains in the Genus database with same CATH superfamily
2BGHA 2RKTA 2DEBA 1DPCA 4KE4A 1SCZA 2H3UA 2JGPA 2RKVA 2ZBAA 3U9BA 1EABA 1T7QA 3FP0A 1T7OA 2II3A 2VSQA 1NDFA 2RCUA 4EPHA 1CIAA 1EACA 1NM8A 4EP9A 4EYWA 1T7NA 2I9DA 5KJUA 4CLAA 1NOCB 1Q6XA 1XL8A 2CLAA 5FANA 1L5AA 3L60A 5KJWA 1EAAA 5DUAA 1S5OA 2E1VA 2FY2A 5KJSA 1XMCA 4HVMA 2FY3A 5T3EA 2II5A 2II4A 1EAFA 3CLAA 5FALA 3MAEA 5DU9A 1QCAA 1E2OA 1DPBA 2IHWA 1NDBA 5KJVA 3U9FA 3B2SA 5KJTA 1PD5A 1CLAA 2FYOA 1C4TA 4N72A 1EAEA 2XR7A 2FW3A 4G22A 4JN3A 3B30A 1Q23A 1XL7A 2E1UA 2H4TA 1DPDA 1XMDA 1NDIA 1EADA 3FOTA 2E1TA 4G2MA 2FY5A 2FY4A 2H3PA 1Q9JA 4G0BA 1T1UA 4JN5A 4KECA 2H3WA 2XHGA
chains in the Genus database with same CATH topology
2E1UA 1DPDA 1XMDA 3CLAA 5FALA 2I9DA 5KJUA 3MAEA 1L5AA 1EADA 2BGHA 4CLAA 1NOCB 2RKTA 5DU9A 3FOTA 1DPCA 1XL8A 2CLAA 1QCAA 1E2OA 1DPBA 1SCZA 2E1TA 2IHWA 3L60A 4G2MA 4KE4A 5FANA 1EAAA 5DUAA 2JGPA 5KJWA 5KJVA 2RKVA 2ZBAA 1Q9JA 3U9BA 1EABA 2E1VA 3B2SA 3U9FA 5KJTA 4G0BA 5KJSA 1PD5A 1XL7A 1CLAA 1XMCA 4HVMA 3FP0A 2II3A 2VSQA 4JN5A 1C4TA 4KECA 4N72A 5T3EA 1EAEA 2XR7A 4G22A 1CIAA 1EACA 2II5A 2II4A 4JN3A 3B30A 1Q23A 2XHGA 1EAFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2E1U A;  1DPD A;  1XMD A;  3CLA A;  5FAL A;  2I9D A;  5KJU A;  3MAE A;  1L5A A;  1EAD A;  2BGH A;  4CLA A;  1NOC B;  2RKT A;  5DU9 A;  3FOT A;  1DPC A;  1XL8 A;  2CLA A;  1QCA A;  1E2O A;  1DPB A;  1SCZ A;  2E1T A;  2IHW A;  3L60 A;  4G2M A;  4KE4 A;  5FAN A;  1EAA A;  5DUA A;  2JGP A;  5KJW A;  5KJV A;  2RKV A;  2ZBA A;  1Q9J A;  3U9B A;  1EAB A;  2E1V A;  3B2S A;  3U9F A;  5KJT A;  4G0B A;  5KJS A;  1PD5 A;  1XL7 A;  1CLA A;  1XMC A;  4HVM A;  3FP0 A;  2II3 A;  2VSQ A;  4JN5 A;  1C4T A;  4KEC A;  4N72 A;  5T3E A;  1EAE A;  2XR7 A;  4G22 A;  1CIA A;  1EAC A;  2II5 A;  2II4 A;  4JN3 A;  3B30 A;  1Q23 A;  2XHG A;  1EAF A; 
#chains in the Genus database with same CATH topology
 2BGH A;  2RKT A;  2DEB A;  1DPC A;  4KE4 A;  1SCZ A;  2H3U A;  2JGP A;  2RKV A;  2ZBA A;  3U9B A;  1EAB A;  1T7Q A;  3FP0 A;  1T7O A;  2II3 A;  2VSQ A;  1NDF A;  2RCU A;  4EPH A;  1CIA A;  1EAC A;  1NM8 A;  4EP9 A;  4EYW A;  1T7N A;  2I9D A;  5KJU A;  4CLA A;  1NOC B;  1Q6X A;  1XL8 A;  2CLA A;  5FAN A;  1L5A A;  3L60 A;  5KJW A;  1EAA A;  5DUA A;  1S5O A;  2E1V A;  2FY2 A;  5KJS A;  1XMC A;  4HVM A;  2FY3 A;  5T3E A;  2II5 A;  2II4 A;  1EAF A;  3CLA A;  5FAL A;  3MAE A;  5DU9 A;  1QCA A;  1E2O A;  1DPB A;  2IHW A;  1NDB A;  5KJV A;  3U9F A;  3B2S A;  5KJT A;  1PD5 A;  1CLA A;  2FYO A;  1C4T A;  4N72 A;  1EAE A;  2XR7 A;  2FW3 A;  4G22 A;  4JN3 A;  3B30 A;  1Q23 A;  1XL7 A;  2E1U A;  2H4T A;  1DPD A;  1XMD A;  1NDI A;  1EAD A;  3FOT A;  2E1T A;  4G2M A;  2FY5 A;  2FY4 A;  2H3P A;  1Q9J A;  4G0B A;  1T1U A;  4JN5 A;  4KEC A;  2H3W A;  2XHG A; 
#chains in the Genus database with same CATH homology
 2E1U A;  1DPD A;  1XMD A;  3CLA A;  5FAL A;  2I9D A;  5KJU A;  3MAE A;  1L5A A;  1EAD A;  2BGH A;  4CLA A;  1NOC B;  2RKT A;  5DU9 A;  3FOT A;  1DPC A;  1XL8 A;  2CLA A;  1QCA A;  1E2O A;  1DPB A;  1SCZ A;  2E1T A;  2IHW A;  3L60 A;  4G2M A;  4KE4 A;  5FAN A;  1EAA A;  5DUA A;  2JGP A;  5KJW A;  5KJV A;  2RKV A;  2ZBA A;  1Q9J A;  3U9B A;  1EAB A;  2E1V A;  3B2S A;  3U9F A;  5KJT A;  4G0B A;  5KJS A;  1PD5 A;  1XL7 A;  1CLA A;  1XMC A;  4HVM A;  3FP0 A;  2II3 A;  2VSQ A;  4JN5 A;  1C4T A;  4KEC A;  4N72 A;  5T3E A;  1EAE A;  2XR7 A;  4G22 A;  1CIA A;  1EAC A;  2II5 A;  2II4 A;  4JN3 A;  3B30 A;  1Q23 A;  2XHG A;  1EAF A; 
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similar chains in the Genus database (?% sequence similarity)
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#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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