3L60A

Crystal structure of branched-chain alpha-keto acid dehydrogenase subunit e2 from mycobacterium tuberculosis
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
229
structure length
229
Chain Sequence
PDVRPVHGVHARMAEKMTLSHKEIPTAKASVEVICAELLRLRDRFVSAAPEITPFALTLRLLVIALKHNVILNSTWVDSGEGPQVHVHRGVHLGFGAATERGLLVPVVTDAQDKNTRELASRVAELITGAREGTLTPAELRGSTFTVSNFGALGVDDGVPVINHPEAAILGLGAIKPRPVVVGGEVVARPTMTLTCVFDHRVVDGAQVAQFMCELRDLIESPETALLDL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of Branched-Chain Alpha-Keto Acid Dehydrogenase Subunit E2 from Mycobacterium Tuberculosis
rcsb
molecule tags Oxidoreductase
source organism Mycobacterium tuberculosis
molecule keywords BRANCHED-CHAIN ALPHA-KETO ACID DEHYDROGENASE
total genus 69
structure length 229
sequence length 229
ec nomenclature ec 2.3.1.168: Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase.
pdb deposition date 2009-12-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00198 2-oxoacid_dh 2-oxoacid dehydrogenases acyltransferase (catalytic domain)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.559.10 Alpha Beta 2-Layer Sandwich Chloramphenicol Acetyltransferase Chloramphenicol acetyltransferase-like domain 3l60A01
1EACA 1NOCB 2IHWA 2ZBAA 5KJTA 1CLAA 4HVMA 2I9DA 1EAFA 4KECA 2JGPA 1L5AA 1DPBA 1DPDA 1Q9JA 1XMDA 5DU9A 1EAEA 2RKTA 1QCAA 1DPCA 4G0BA 4N72A 3U9BA 2II5A 2XHGA 3FP0A 5KJWA 1PD5A 1SCZA 5FALA 2E1UA 2II3A 4G22A 3FOTA 2VSQA 3B2SA 5KJSA 1XMCA 1XL8A 4G2MA 4JN5A 1Q23A 3CLAA 1CIAA 3U9FA 4KE4A 3L60A 5FANA 1E2OA 2CLAA 2XR7A 4CLAA 5KJVA 5DUAA 1EAAA 5KJUA 2BGHA 2II4A 2E1VA 4JN3A 5T3EA 1EABA 1XL7A 2RKVA 3MAEA 3B30A 1C4TA 2E1TA 1EADA
chains in the Genus database with same CATH superfamily
5KJTA 1CLAA 1NDFA 2FY3A 1EAFA 2JGPA 1NM8A 1PD5A 1SCZA 2II3A 2VSQA 1XMCA 2FY2A 4KE4A 5FANA 4EYWA 4CLAA 5KJUA 2BGHA 4JN3A 2RCUA 2H3WA 5DU9A 1XMDA 2FW3A 1Q6XA 1NDIA 4G0BA 4N72A 3U9BA 2XHGA 1T7OA 3FP0A 5KJWA 4EP9A 1T7QA 1CIAA 3U9FA 3L60A 1E2OA 5KJVA 5DUAA 1T7NA 2E1VA 1XL7A 1C4TA 3FOTA 1EADA 2IHWA 2ZBAA 2I9DA 2FY5A 1DPBA 1DPDA 1Q9JA 1EAEA 1T1UA 1QCAA 5FALA 2E1UA 4G22A 2FYOA 1XL8A 1Q23A 3CLAA 2DEBA 2CLAA 2XR7A 1NDBA 2FY4A 2II4A 5T3EA 1EABA 4EPHA 3MAEA 3B30A 2H3UA 2E1TA 1EACA 1NOCB 4HVMA 4KECA 1L5AA 2H3PA 2RKTA 1DPCA 1S5OA 5KJSA 3B2SA 4G2MA 4JN5A 2H4TA 1EAAA 2RKVA 2II5A
chains in the Genus database with same CATH topology
1EACA 1NOCB 2IHWA 2ZBAA 5KJTA 1CLAA 4HVMA 2I9DA 1EAFA 4KECA 2JGPA 1L5AA 1DPBA 1DPDA 1Q9JA 1XMDA 5DU9A 1EAEA 2RKTA 1QCAA 1DPCA 4G0BA 4N72A 3U9BA 2II5A 2XHGA 3FP0A 5KJWA 1PD5A 1SCZA 5FALA 2E1UA 2II3A 4G22A 3FOTA 2VSQA 3B2SA 5KJSA 1XMCA 1XL8A 4G2MA 4JN5A 1Q23A 3CLAA 1CIAA 3U9FA 4KE4A 3L60A 5FANA 1E2OA 2CLAA 2XR7A 4CLAA 5KJVA 5DUAA 1EAAA 5KJUA 2BGHA 2II4A 2E1VA 4JN3A 5T3EA 1EABA 1XL7A 2RKVA 3MAEA 3B30A 1C4TA 2E1TA 1EADA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1EAC A;  1NOC B;  2IHW A;  2ZBA A;  5KJT A;  1CLA A;  4HVM A;  2I9D A;  1EAF A;  4KEC A;  2JGP A;  1L5A A;  1DPB A;  1DPD A;  1Q9J A;  1XMD A;  5DU9 A;  1EAE A;  2RKT A;  1QCA A;  1DPC A;  4G0B A;  4N72 A;  3U9B A;  2II5 A;  2XHG A;  3FP0 A;  5KJW A;  1PD5 A;  1SCZ A;  5FAL A;  2E1U A;  2II3 A;  4G22 A;  3FOT A;  2VSQ A;  3B2S A;  5KJS A;  1XMC A;  1XL8 A;  4G2M A;  4JN5 A;  1Q23 A;  3CLA A;  1CIA A;  3U9F A;  4KE4 A;  3L60 A;  5FAN A;  1E2O A;  2CLA A;  2XR7 A;  4CLA A;  5KJV A;  5DUA A;  1EAA A;  5KJU A;  2BGH A;  2II4 A;  2E1V A;  4JN3 A;  5T3E A;  1EAB A;  1XL7 A;  2RKV A;  3MAE A;  3B30 A;  1C4T A;  2E1T A;  1EAD A; 
#chains in the Genus database with same CATH topology
 5KJT A;  1CLA A;  1NDF A;  2FY3 A;  1EAF A;  2JGP A;  1NM8 A;  1PD5 A;  1SCZ A;  2II3 A;  2VSQ A;  1XMC A;  2FY2 A;  4KE4 A;  5FAN A;  4EYW A;  4CLA A;  5KJU A;  2BGH A;  4JN3 A;  2RCU A;  2H3W A;  5DU9 A;  1XMD A;  2FW3 A;  1Q6X A;  1NDI A;  4G0B A;  4N72 A;  3U9B A;  2XHG A;  1T7O A;  3FP0 A;  5KJW A;  4EP9 A;  1T7Q A;  1CIA A;  3U9F A;  3L60 A;  1E2O A;  5KJV A;  5DUA A;  1T7N A;  2E1V A;  1XL7 A;  1C4T A;  3FOT A;  1EAD A;  2IHW A;  2ZBA A;  2I9D A;  2FY5 A;  1DPB A;  1DPD A;  1Q9J A;  1EAE A;  1T1U A;  1QCA A;  5FAL A;  2E1U A;  4G22 A;  2FYO A;  1XL8 A;  1Q23 A;  3CLA A;  2DEB A;  2CLA A;  2XR7 A;  1NDB A;  2FY4 A;  2II4 A;  5T3E A;  1EAB A;  4EPH A;  3MAE A;  3B30 A;  2H3U A;  2E1T A;  1EAC A;  1NOC B;  4HVM A;  4KEC A;  1L5A A;  2H3P A;  2RKT A;  1DPC A;  1S5O A;  5KJS A;  3B2S A;  4G2M A;  4JN5 A;  2H4T A;  1EAA A;  2RKV A;  2II5 A; 
#chains in the Genus database with same CATH homology
 1EAC A;  1NOC B;  2IHW A;  2ZBA A;  5KJT A;  1CLA A;  4HVM A;  2I9D A;  1EAF A;  4KEC A;  2JGP A;  1L5A A;  1DPB A;  1DPD A;  1Q9J A;  1XMD A;  5DU9 A;  1EAE A;  2RKT A;  1QCA A;  1DPC A;  4G0B A;  4N72 A;  3U9B A;  2II5 A;  2XHG A;  3FP0 A;  5KJW A;  1PD5 A;  1SCZ A;  5FAL A;  2E1U A;  2II3 A;  4G22 A;  3FOT A;  2VSQ A;  3B2S A;  5KJS A;  1XMC A;  1XL8 A;  4G2M A;  4JN5 A;  1Q23 A;  3CLA A;  1CIA A;  3U9F A;  4KE4 A;  3L60 A;  5FAN A;  1E2O A;  2CLA A;  2XR7 A;  4CLA A;  5KJV A;  5DUA A;  1EAA A;  5KJU A;  2BGH A;  2II4 A;  2E1V A;  4JN3 A;  5T3E A;  1EAB A;  1XL7 A;  2RKV A;  3MAE A;  3B30 A;  1C4T A;  2E1T A;  1EAD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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