3NVYC

Crystal structure of bovine xanthine oxidase in complex with quercetin
Total Genus 261
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
261
sequence length
756
structure length
756
Chain Sequence
DTVGRPLPHLAAAMQASGEAVYCDDIPRYENELFLRLVTSTRAHAKIKSIDVSEAQKVPGFVCFLSADDIPGSNETGLFNDETVFAKDTVTCVGHIIGAVVADTPEHAERAAHVVKVTYEDLPAIITIEDAIKNNSFYGSELKIEKGDLKKGFSEADNVVSGELYIGGQDHFYLETHCTIAIPKGEEGEMELFVSTQNAMKTQSFVAKMLGVPVNRILVRVKRMGGGFGGKETRSTLVSVAVALAAYKTGHPVRCMLDRNEDMLITGGRHPFLARYKVGFMKTGTIVALEVDHYSNAGNSRDLSHSIMERALFHMDNCYKIPNIRGTGRLCKTNLSSNTAFRGFGGPQALFIAENWMSEVAVTCGLPAEEVRWKNMYKEGDLTHFNQRLEGFSVPRCWDECLKSSQYYARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGALIHVYTDGSVLVSHGGTEMGQGLHTKMVQVASKALKIPISKIYISETSTNTVPNSSPTAASVSTDIYGQAVYEACQTILKRLEPFKKKNPDGSWEDWVMAAYQDRVSLSTTGFYRTPNLGYSFETNSGNAFHYFTYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFVQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPTEFRVSLLRDCPNKKAIYASKAVGEPPLFLGASVFFAIKDAIRAARAQHTNNNTKELFRLDSPATPEKIRNACVDKFTTLCVTGAPGNCK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title X-ray Crystal Structure of a Xanthine Oxidase Complex with the Flavonoid Inhibitor Quercetin.
pubmed doi rcsb
molecule tags Oxidoreductase
molecule keywords Xanthine dehydrogenase/oxidase
total genus 261
structure length 756
sequence length 756
chains with identical sequence L
ec nomenclature ec 1.17.1.4: Xanthine dehydrogenase.
pdb deposition date 2010-07-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF01315 Ald_Xan_dh_C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain
C PF02738 Ald_Xan_dh_C2 Molybdopterin-binding domain of aldehyde dehydrogenase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.365.10 Alpha Beta 2-Layer Sandwich Aldehyde Oxidoreductase; domain 4 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain 3nvyC02
3.30.365.10 Alpha Beta 2-Layer Sandwich Aldehyde Oxidoreductase; domain 4 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain 3nvyC05
3.30.365.10 Alpha Beta 2-Layer Sandwich Aldehyde Oxidoreductase; domain 4 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain 3nvyC04
3.30.365.10 Alpha Beta 2-Layer Sandwich Aldehyde Oxidoreductase; domain 4 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain 3nvyC03
3.90.1170.50 Alpha Beta Alpha-Beta Complex Aldehyde Oxidoreductase; domain 3 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead 3nvyC01
1SB3A 3L4PA 3FC4A 3AM9A 1FFUB 1WYGA 1N5XA 1VDVA 3NVZC 1N63B 1FFVB 3SR6C 2E3TA 4C80A 1DGJA 4ZOHA 3EUB4 1FO4A 4US8A 1N5WB 1SIJA 1N62B 4USAA 1ZXIB 1JROB 1JRPB 3FAHA 3NVVC 2W55B 2W3SB 2W54B 1RM6A 3AMZA 3NVYC 3NS1C 3ETRC 2W3RB 1VLBA 1V97A 3NVWC 3AN1A 4C7YA 1FIQC 1N61B 3B9JC 1N60B 3HRDB 3HRDA 4US9A 3NRZC 4C7ZA
chains in the Genus database with same CATH superfamily
1KQSH 1VDVA 3DLLJ 3PAJA 4YYYA 3WNZA 1Q86J 1KC8J 4WFNJ 3PIOJ 5EP8A 1QVFH 3EUB4 1JJ2H 4US8A 1N5WB 3CCVH 5HUOA 3NRZC 3L0GA 5GADN 4IOCJ 3NVVC 3H5QA 2W55B 2W3SB 3NVYC 5AYYA 4EAFA 1Q7YJ 1YTKA 3RPFA 1VQKH 1YITH 3CPWH 3J7ZM 1V97A 1Y69K 2B7NA 4I9AA 1QPNA 3CC2H 2WK6A 1VQOH 1YTEA 1N60B 3HRDB 4KWWA 1VQPH 1M1KJ 1UOUA 1YIJH 2OTLH 1BRWA 3SR6C 1K8AJ 2QA4H 3L4PA 4XR5A 1O4UA 1FM0E 3AM9A 3C2VA 1FFUB 1N5XA 2WK5A 1VQ5H 3C2RA 3CCEH 2E3TA 3OW2H 2ZJRJ 4WFAJ 5HUPA 1SIJA 2J0FA 4USAA 4U67J 3I55H 2QEXH 1VQ9H 1JROB 1JRPB 3FAHA 3C2EA 3AMZA 3CC4H 5AYZA 4GA4A 1N8RJ 2W3RB 1KD1J 3CCSH 3CCLH 2ZJQJ 1Q82J 3AN1A 4C7YA 1NVIE 1FIQC 3WO1A 1YJNH 1QVGH 4US9A 3TQVA 1T3QB 2Q5WE 1FMAE 1QAPA 4C7ZA 2B7QA 1VQ8H 1W2BH 3FC4A 5DM7J 1WYGA 5GAGN 5EY3A 5DM6J 1FFVB 1YHQH 3GNNA 2WP4A 1DGJA 4ZOHA 2I1OA 1QPRA 1M90J 1VQ6H 1AZYA 1Q81J 5GAEN 1S72H 3WO0A 1K73J 4WCEJ 1K9MJ 1WKIA 2W54B 2OMDA 1VQ4H 4X46A 3ETRC 2PA2A 2B7PA 3C2OA 3VMMA 3CMEH 1VLBA 4KWVA 5MPOC 3NVWC 2I14A 3G4SH 4LHMA 3B9JC 5HULA 3HRDA 2TPTA 3G6EH 3C2FA 1QPOA 5HL7J 3CCRH 1YJ9H 2OTJH 1OTPA 1SB3A 5MLCO 1VQLH 1VQ7H 4GA6A 4AP8A 3CMAH 1YI2H 3I56H 2DSJA 5AYXA 3CCQH 1N63B 3CCMH 3CF5J 3CC7H 3CD6H 4WF9J 4C80A 1FO4A 4GA5A 4UY8M 1N62B 2JBMA 3CCJH 1ZXIB 4EADA 1VQNH 4WFBJ 5GAHN 1YJWH 4YEKA 4IO9J 1RM6A 5JVGJ 3NS1C 3G71H 1X1OA 4IOAJ 1NVJA 3CXCH 1QPQA 3PIPJ 1VQMH 2ZJPJ 1N61B 1YTDA 3CCUH 3BIIE 1NJIJ 5AN9F 2QIEA 5H1SO 5JVHJ 3NVZC
chains in the Genus database with same CATH topology
1SB3A 3L4PA 3FC4A 3AM9A 1FFUB 1WYGA 1N5XA 1VDVA 3NVZC 1N63B 1FFVB 3SR6C 2E3TA 4C80A 1DGJA 4ZOHA 3EUB4 1FO4A 4US8A 1N5WB 1SIJA 1N62B 4USAA 1ZXIB 1JROB 1JRPB 3FAHA 3NVVC 2W55B 2W3SB 2W54B 1RM6A 3AMZA 3NVYC 3NS1C 3ETRC 2W3RB 1VLBA 1V97A 3NVWC 3AN1A 4C7YA 1FIQC 1N61B 3B9JC 1N60B 3HRDB 3HRDA 4US9A 3NRZC 4C7ZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1SB3 A;  3L4P A;  3FC4 A;  3AM9 A;  1FFU B;  1WYG A;  1N5X A;  1VDV A;  3NVZ C;  1N63 B;  1FFV B;  3SR6 C;  2E3T A;  4C80 A;  1DGJ A;  4ZOH A;  3EUB 4;  1FO4 A;  4US8 A;  1N5W B;  1SIJ A;  1N62 B;  4USA A;  1ZXI B;  1JRO B;  1JRP B;  3FAH A;  3NVV C;  2W55 B;  2W3S B;  2W54 B;  1RM6 A;  3AMZ A;  3NVY C;  3NS1 C;  3ETR C;  2W3R B;  1VLB A;  1V97 A;  3NVW C;  3AN1 A;  4C7Y A;  1FIQ C;  1N61 B;  3B9J C;  1N60 B;  3HRD B;  3HRD A;  4US9 A;  3NRZ C;  4C7Z A; 
#chains in the Genus database with same CATH topology
 1KQS H;  1VDV A;  3DLL J;  3PAJ A;  4YYY A;  3WNZ A;  1Q86 J;  1KC8 J;  4WFN J;  3PIO J;  5EP8 A;  1QVF H;  3EUB 4;  1JJ2 H;  4US8 A;  1N5W B;  3CCV H;  5HUO A;  3NRZ C;  3L0G A;  5GAD N;  4IOC J;  3NVV C;  3H5Q A;  2W55 B;  2W3S B;  3NVY C;  5AYY A;  4EAF A;  1Q7Y J;  1YTK A;  3RPF A;  1VQK H;  1YIT H;  3CPW H;  3J7Z M;  1V97 A;  1Y69 K;  2B7N A;  4I9A A;  1QPN A;  3CC2 H;  2WK6 A;  1VQO H;  1YTE A;  1N60 B;  3HRD B;  4KWW A;  1VQP H;  1M1K J;  1UOU A;  1YIJ H;  2OTL H;  1BRW A;  3SR6 C;  1K8A J;  2QA4 H;  3L4P A;  4XR5 A;  1O4U A;  1FM0 E;  3AM9 A;  3C2V A;  1FFU B;  1N5X A;  2WK5 A;  1VQ5 H;  3C2R A;  3CCE H;  2E3T A;  3OW2 H;  2ZJR J;  4WFA J;  5HUP A;  1SIJ A;  2J0F A;  4USA A;  4U67 J;  3I55 H;  2QEX H;  1VQ9 H;  1JRO B;  1JRP B;  3FAH A;  3C2E A;  3AMZ A;  3CC4 H;  5AYZ A;  4GA4 A;  1N8R J;  2W3R B;  1KD1 J;  3CCS H;  3CCL H;  2ZJQ J;  1Q82 J;  3AN1 A;  4C7Y A;  1NVI E;  1FIQ C;  3WO1 A;  1YJN H;  1QVG H;  4US9 A;  3TQV A;  1T3Q B;  2Q5W E;  1FMA E;  1QAP A;  4C7Z A;  2B7Q A;  1VQ8 H;  1W2B H;  3FC4 A;  5DM7 J;  1WYG A;  5GAG N;  5EY3 A;  5DM6 J;  1FFV B;  1YHQ H;  3GNN A;  2WP4 A;  1DGJ A;  4ZOH A;  2I1O A;  1QPR A;  1M90 J;  1VQ6 H;  1AZY A;  1Q81 J;  5GAE N;  1S72 H;  3WO0 A;  1K73 J;  4WCE J;  1K9M J;  1WKI A;  2W54 B;  2OMD A;  1VQ4 H;  4X46 A;  3ETR C;  2PA2 A;  2B7P A;  3C2O A;  3VMM A;  3CME H;  1VLB A;  4KWV A;  5MPO C;  3NVW C;  2I14 A;  3G4S H;  4LHM A;  3B9J C;  5HUL A;  3HRD A;  2TPT A;  3G6E H;  3C2F A;  1QPO A;  5HL7 J;  3CCR H;  1YJ9 H;  2OTJ H;  1OTP A;  1SB3 A;  5MLC O;  1VQL H;  1VQ7 H;  4GA6 A;  4AP8 A;  3CMA H;  1YI2 H;  3I56 H;  2DSJ A;  5AYX A;  3CCQ H;  1N63 B;  3CCM H;  3CF5 J;  3CC7 H;  3CD6 H;  4WF9 J;  4C80 A;  1FO4 A;  4GA5 A;  4UY8 M;  1N62 B;  2JBM A;  3CCJ H;  1ZXI B;  4EAD A;  1VQN H;  4WFB J;  5GAH N;  1YJW H;  4YEK A;  4IO9 J;  1RM6 A;  5JVG J;  3NS1 C;  3G71 H;  1X1O A;  4IOA J;  1NVJ A;  3CXC H;  1QPQ A;  3PIP J;  1VQM H;  2ZJP J;  1N61 B;  1YTD A;  3CCU H;  3BII E;  1NJI J;  5AN9 F;  2QIE A;  5H1S O;  5JVH J;  3NVZ C; 
#chains in the Genus database with same CATH homology
 1SB3 A;  3L4P A;  3FC4 A;  3AM9 A;  1FFU B;  1WYG A;  1N5X A;  1VDV A;  3NVZ C;  1N63 B;  1FFV B;  3SR6 C;  2E3T A;  4C80 A;  1DGJ A;  4ZOH A;  3EUB 4;  1FO4 A;  4US8 A;  1N5W B;  1SIJ A;  1N62 B;  4USA A;  1ZXI B;  1JRO B;  1JRP B;  3FAH A;  3NVV C;  2W55 B;  2W3S B;  2W54 B;  1RM6 A;  3AMZ A;  3NVY C;  3NS1 C;  3ETR C;  2W3R B;  1VLB A;  1V97 A;  3NVW C;  3AN1 A;  4C7Y A;  1FIQ C;  1N61 B;  3B9J C;  1N60 B;  3HRD B;  3HRD A;  4US9 A;  3NRZ C;  4C7Z A; 
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