4JN5A

Crystal structures of the first condensation domain of the cda synthetase
Total Genus 141
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
141
sequence length
446
structure length
435
Chain Sequence
NSSVRHGLTSAQHEVWLAQQLDPRGAHYRTGSCLEIDGPLDHAVLSRALRLTVAGTETLCSRFLTDEEGRPYRAYCPPAPEGSAAVEDPDGVPYTPVLLRHIDLSGHEDPEGEAQRWMDRDRATPLPLDRPGLSSHALFTLGGGRHLYYLGVHHIVIDGTSMALFYERLAEVYRALRDGRAVPAAAFGDTDRMVAGEEAYRASARYERDRAYWTGLFTDGGRALAPTVRSLGLPPERTEVLGRAAEATGAHWARVVIAGVAAFLHRTTGARDVVVSVPVTGRYGANARITPGMVSNRLPLRLAVRPGESFARVVETVSEAMSGLLAHSRFRGEDLDRELGGAGVSGPTVNVMPYIRPVDFGGPVGLMRSISSGPTTDLNIVLTGTPESGLRVDFEGNPQVYGGQDLTVLQERFVRFLAELAADPAATVDEVALLT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structures of the First Condensation Domain of CDA Synthetase Suggest Conformational Changes during the Synthetic Cycle of Nonribosomal Peptide Synthetases.
pubmed doi rcsb
molecule tags Biosynthetic protein
source organism Streptomyces coelicolor
molecule keywords CDA peptide synthetase I
total genus 141
structure length 435
sequence length 446
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-03-14
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.559.10 Alpha Beta 2-Layer Sandwich Chloramphenicol Acetyltransferase Chloramphenicol acetyltransferase-like domain 4jn5A01
3.30.559.30 Alpha Beta 2-Layer Sandwich Chloramphenicol Acetyltransferase Chloramphenicol Acetyltransferase 4jn5A02
2JGPA 5KJWA 1EABA 5FANA 2II4A 1Q9JA 3FOTA 2I9DA 1EAEA 1SCZA 2RKTA 4KE4A 1NOCB 3FP0A 4N72A 2VSQA 2RKVA 1L5AA 3U9FA 1DPDA 2E1TA 2II5A 2IHWA 4CLAA 1XL7A 3CLAA 5KJVA 1EADA 1EACA 3B30A 5FALA 1E2OA 2E1VA 3L60A 5KJSA 5T3EA 2XHGA 4G0BA 1XL8A 4KECA 1DPCA 1EAFA 4JN5A 5DUAA 5KJUA 3B2SA 5DU9A 2BGHA 1PD5A 4G2MA 4JN3A 1C4TA 3U9BA 5KJTA 1CIAA 2E1UA 2CLAA 1DPBA 2II3A 1Q23A 2ZBAA 3MAEA 4G22A 1EAAA 1QCAA 1XMDA 1CLAA 2XR7A 4HVMA 1XMCA
chains in the Genus database with same CATH superfamily
2II4A 2I9DA 2FW3A 4N72A 1NDFA 3FP0A 2FY3A 2VSQA 2RKVA 2II5A 1XL7A 1Q6XA 1EADA 1EACA 1NDIA 2H3WA 2FYOA 2XHGA 4G0BA 1EAFA 5KJUA 2H4TA 2CLAA 1DPBA 2ZBAA 1QCAA 1XMDA 1NM8A 2RCUA 4HVMA 2JGPA 5FANA 1Q9JA 1SCZA 2RKTA 1NOCB 1NDBA 1T1UA 1DPDA 4CLAA 2FY4A 3CLAA 5FALA 3L60A 5KJSA 5T3EA 4JN5A 2H3PA 1T7OA 1PD5A 1C4TA 1CIAA 4G22A 4EP9A 5KJWA 1EAEA 1L5AA 5KJVA 1E2OA 2FY2A 1T7NA 1XL8A 1DPCA 3B2SA 5DU9A 2BGHA 4G2MA 4JN3A 3U9BA 5KJTA 2II3A 1Q23A 3MAEA 1CLAA 2H3UA 4EPHA 1EABA 3FOTA 4KE4A 3U9FA 2E1TA 2IHWA 2FY5A 3B30A 2DEBA 2E1VA 4EYWA 1S5OA 4KECA 5DUAA 2E1UA 1EAAA 2XR7A 1XMCA 1T7QA
chains in the Genus database with same CATH topology
2II4A 2I9DA 2FW3A 4N72A 1NDFA 3FP0A 2FY3A 2VSQA 2RKVA 2II5A 1XL7A 1Q6XA 1EADA 1EACA 1NDIA 2H3WA 2FYOA 2XHGA 4G0BA 1EAFA 5KJUA 2H4TA 2CLAA 1DPBA 2ZBAA 1QCAA 1XMDA 1NM8A 2RCUA 4HVMA 2JGPA 5FANA 1Q9JA 1SCZA 2RKTA 1NOCB 1NDBA 1T1UA 1DPDA 4CLAA 3CLAA 2FY4A 5FALA 3L60A 5KJSA 5T3EA 4JN5A 2H3PA 1T7OA 1PD5A 1C4TA 1CIAA 4G22A 4EP9A 5KJWA 1EAEA 1L5AA 5KJVA 1E2OA 2FY2A 1T7NA 1XL8A 1DPCA 3B2SA 5DU9A 2BGHA 4G2MA 4JN3A 3U9BA 5KJTA 2II3A 1Q23A 3MAEA 1CLAA 2H3UA 4EPHA 1EABA 3FOTA 4KE4A 3U9FA 2E1TA 2IHWA 2FY5A 3B30A 2DEBA 2E1VA 4EYWA 1S5OA 4KECA 5DUAA 2E1UA 1EAAA 2XR7A 1XMCA 1T7QA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JGP A;  5KJW A;  1EAB A;  5FAN A;  2II4 A;  1Q9J A;  3FOT A;  2I9D A;  1EAE A;  1SCZ A;  2RKT A;  4KE4 A;  1NOC B;  3FP0 A;  4N72 A;  2VSQ A;  2RKV A;  1L5A A;  3U9F A;  1DPD A;  2E1T A;  2II5 A;  2IHW A;  4CLA A;  1XL7 A;  3CLA A;  5KJV A;  1EAD A;  1EAC A;  3B30 A;  5FAL A;  1E2O A;  2E1V A;  3L60 A;  5KJS A;  5T3E A;  2XHG A;  4G0B A;  1XL8 A;  4KEC A;  1DPC A;  1EAF A;  4JN5 A;  5DUA A;  5KJU A;  3B2S A;  5DU9 A;  2BGH A;  1PD5 A;  4G2M A;  4JN3 A;  1C4T A;  3U9B A;  5KJT A;  1CIA A;  2E1U A;  2CLA A;  1DPB A;  2II3 A;  1Q23 A;  2ZBA A;  3MAE A;  4G22 A;  1EAA A;  1QCA A;  1XMD A;  1CLA A;  2XR7 A;  4HVM A;  1XMC A; 
#chains in the Genus database with same CATH topology
 2II4 A;  2I9D A;  2FW3 A;  4N72 A;  1NDF A;  3FP0 A;  2FY3 A;  2VSQ A;  2RKV A;  2II5 A;  1XL7 A;  1Q6X A;  1EAD A;  1EAC A;  1NDI A;  2H3W A;  2FYO A;  2XHG A;  4G0B A;  1EAF A;  5KJU A;  2H4T A;  2CLA A;  1DPB A;  2ZBA A;  1QCA A;  1XMD A;  1NM8 A;  2RCU A;  4HVM A;  2JGP A;  5FAN A;  1Q9J A;  1SCZ A;  2RKT A;  1NOC B;  1NDB A;  1T1U A;  1DPD A;  4CLA A;  2FY4 A;  3CLA A;  5FAL A;  3L60 A;  5KJS A;  5T3E A;  4JN5 A;  2H3P A;  1T7O A;  1PD5 A;  1C4T A;  1CIA A;  4G22 A;  4EP9 A;  5KJW A;  1EAE A;  1L5A A;  5KJV A;  1E2O A;  2FY2 A;  1T7N A;  1XL8 A;  1DPC A;  3B2S A;  5DU9 A;  2BGH A;  4G2M A;  4JN3 A;  3U9B A;  5KJT A;  2II3 A;  1Q23 A;  3MAE A;  1CLA A;  2H3U A;  4EPH A;  1EAB A;  3FOT A;  4KE4 A;  3U9F A;  2E1T A;  2IHW A;  2FY5 A;  3B30 A;  2DEB A;  2E1V A;  4EYW A;  1S5O A;  4KEC A;  5DUA A;  2E1U A;  1EAA A;  2XR7 A;  1XMC A;  1T7Q A; 
#chains in the Genus database with same CATH homology
 2II4 A;  2I9D A;  2FW3 A;  4N72 A;  1NDF A;  3FP0 A;  2FY3 A;  2VSQ A;  2RKV A;  2II5 A;  1XL7 A;  1Q6X A;  1EAD A;  1EAC A;  1NDI A;  2H3W A;  2FYO A;  2XHG A;  4G0B A;  1EAF A;  5KJU A;  2H4T A;  2CLA A;  1DPB A;  2ZBA A;  1QCA A;  1XMD A;  1NM8 A;  2RCU A;  4HVM A;  2JGP A;  5FAN A;  1Q9J A;  1SCZ A;  2RKT A;  1NOC B;  1NDB A;  1T1U A;  1DPD A;  4CLA A;  3CLA A;  2FY4 A;  5FAL A;  3L60 A;  5KJS A;  5T3E A;  4JN5 A;  2H3P A;  1T7O A;  1PD5 A;  1C4T A;  1CIA A;  4G22 A;  4EP9 A;  5KJW A;  1EAE A;  1L5A A;  5KJV A;  1E2O A;  2FY2 A;  1T7N A;  1XL8 A;  1DPC A;  3B2S A;  5DU9 A;  2BGH A;  4G2M A;  4JN3 A;  3U9B A;  5KJT A;  2II3 A;  1Q23 A;  3MAE A;  1CLA A;  2H3U A;  4EPH A;  1EAB A;  3FOT A;  4KE4 A;  3U9F A;  2E1T A;  2IHW A;  2FY5 A;  3B30 A;  2DEB A;  2E1V A;  4EYW A;  1S5O A;  4KEC A;  5DUA A;  2E1U A;  1EAA A;  2XR7 A;  1XMC A;  1T7Q A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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