The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
58
|
sequence length |
251
|
structure length |
250
|
Chain Sequence |
MSEKLQKVLARAGHGSRREIESIIEAGRVSVDGKIAKLGDRVEVTPGLKIRIDGHLISVRESAEQICRVLAYYKPEGELCTRNDPEGRPTVFDRLPKLRGARWIAVGRLDVNTGLLLFTTDGELANRLMHPSREVEREYAVRVFGQVDDAKLRDLSRGVQLEDGPAAFKTIKFSGGEGINQWYNVTLTEGRNREVRRLWEAVGVQVSRLIRVRYGDIPLPKGLPRGGWTELDLAQTNYLRELVELPPETS
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
The mechanism of pseudouridine synthases from a covalent complex with RNA, and alternate specificity for U2605 versus U2604 between close homologs.
pubmed doi rcsb |
| molecule tags |
Isomerase/rna
|
| source organism |
Escherichia coli
|
| molecule keywords |
Ribosomal large subunit pseudouridine synthase B
|
| total genus |
58
|
| structure length |
250
|
| sequence length |
251
|
| chains with identical sequence |
D
|
| ec nomenclature |
ec
5.4.99.22: 23S rRNA pseudouridine(2605) synthase. |
| pdb deposition date | 2013-06-28 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF00849 | PseudoU_synth_2 | RNA pseudouridylate synthase |
| A | PF01479 | S4 | S4 domain |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Alpha Beta | Roll | Structural Genomics Hypothetical 15.5 Kd Protein In mrcA-pckA Intergenic Region; Chain A | RNA-binding S4 domain | ||
| Alpha Beta | 2-Layer Sandwich | Pseudouridine synthase | Pseudouridine synthase |
#chains in the Genus database with same CATH superfamily 1XNQ D; 4JI5 D; 4DR2 D; 2UUA D; 4LF7 D; 4YY3 D; 2JAN A; 4DV0 D; 4LF9 D; 3LWV A; 3HAX A; 4DV2 D; 1HNW D; 4DV7 D; 4JI1 D; 4B3S D; 1P9K A; 3T1Y D; 4DR5 D; 1HR0 D; 3T1H D; 3HJY A; 3OTO D; 1N32 D; 2UUC D; 1N33 D; 4JI6 D; 1KSV A; 3LWP A; 2AB4 A; 4JYA D; 4LGT A; 2I82 A; 4JI0 D; 2IST A; 2E5L D; 4DR3 D; 3LWQ A; 1IBL D; 1ZL3 A; 4X66 D; 1XMQ D; 2UUB D; 4X64 D; 4DV3 D; 1I94 D; 4JI4 D; 4LF4 D; 4DR7 D; 1C05 A; 5BR8 D; 2HVY A; 4LFC D; 1JH3 A; 4DV4 D; 1XNR D; 4X65 D; 2UXC D; 3KBG A; 4LF5 D; 1PRZ A; 4NXM D; 1R3F A; 4LF8 D; 1SGV A; 5LMU D; 4DV6 D; 4DUZ D; 4NXN D; 4JI7 D; 1C06 A; 5IWA D; 4GKJ D; 1V9F A; 1R3E A; 4DUY D; 2RFK A; 4OX9 D; 4DR4 D; 1KSL A; 1XPI A; 3UAI A; 3LWR A; 2K6P A; 1HNX D; 2HHH D; 4B3M D; 2VQE D; 4GKK D; 4DR6 D; 1QYU A; 3HP7 A; 1DM9 A; 1FJG D; 1IBK D; 1ZE2 A; 1KSK A; 1J5E D; 1FKA D; 4JI8 D; 3LWO A; 2EY4 A; 4LAB A; 2KTL A; 2F4V D; 4JI3 D; 4LF6 D; 4DV5 D; 2UXD D; 4YHH D; 4LFA D; 4B3R D; 2UXB D; 1N36 D; 3U28 A; 4DR1 D; 1N34 D; 3MQK A; 2VQF D; 4LFB D; 1K8W A; 1H3E A; 2UU9 D; 3DH3 A; 4JI2 D; 1VIO A; 4KHP D; 1ZE1 A; 1IBM D; 4AQY D; 1V9K A; 5LMN D; 2ZM6 D; 3HJW A; 1HNZ D; 4X62 D; 2APO A; 1XMO D; 4B3T D; 4DV1 D; 2AUS A; 1H3F A; 4OUD A; 4K0K D; 4JV5 D; #chains in the Genus database with same CATH topology 1XNQ D; 4JI5 D; 4DR2 D; 2UUA D; 4LF7 D; 4W5V B; 4YY3 D; 2JAN A; 4DV0 D; 4LF9 D; 3LWV A; 3HAX A; 4DV2 D; 1HNW D; 4DV7 D; 4JI1 D; 4B3S D; 1P9K A; 3T1Y D; 4DR5 D; 1HR0 D; 3T1H D; 3HJY A; 3OTO D; 1N32 D; 2UUC D; 1N33 D; 4JI6 D; 1KSV A; 3LWP A; 2AB4 A; 4JYA D; 4LGT A; 3J7A F; 2I82 A; 4JI0 D; 3ONG A; 2IST A; 2E5L D; 4DR3 D; 3LWQ A; 1IBL D; 1ZL3 A; 4X66 D; 1XMQ D; 2UUB D; 4X64 D; 4DV3 D; 1I94 D; 4JI4 D; 4LF4 D; 5A2Q E; 4DR7 D; 1C05 A; 5BR8 D; 2HVY A; 4LFC D; 1JH3 A; 4DV4 D; 2I1S A; 1SZW A; 1XNR D; 4X65 D; 2UXC D; 2LQ7 A; 3KBG A; 4LF5 D; 1PRZ A; 4NXM D; 1R3F A; 4LF8 D; 1SGV A; 5LMU D; 4DV6 D; 4DUZ D; 4NXN D; 1Y8X B; 4JI7 D; 1C06 A; 5IWA D; 4GKJ D; 1V9F A; 1R3E A; 4DUY D; 2RFK A; 2ZTB A; 4OX9 D; 4DR4 D; 1KSL A; 1XPI A; 3UAI A; 3LWR A; 1Y8R B; 2K6P A; 5FQ2 B; 5LL6 S; 1HNX D; 2NVU B; 2HHH D; 4B3M D; 2VQE D; 4GKK D; 4DR6 D; 1QYU A; 3HP7 A; 1DM9 A; 1FJG D; 3CMM A; 4NNJ A; 1IBK D; 3KYD B; 3JAM E; 1ZE2 A; 1KSK A; 1J5E D; 1FKA D; 4JI8 D; 3LWO A; 2EY4 A; 4LAB A; 2KTL A; 2F4V D; 1SI7 A; 4JI3 D; 4LF6 D; 4DV5 D; 2UXD D; 1Y8Q B; 4II2 A; 4YHH D; 4LFA D; 4B3R D; 4II3 A; 2UXB D; 1SB7 A; 1N36 D; 3ONH A; 4DR1 D; 3U28 A; 1N34 D; 3MQK A; 2VQF D; 5KNL A; 4LFB D; 1K8W A; 1H3E A; 2UU9 D; 3DH3 A; 3FN1 A; 5IT9 E; 4JI2 D; 1Z2Z A; 1VIO A; 4KHP D; 3KYC B; 3J80 E; 1ZE1 A; 1IBM D; 3J81 E; 4AQY D; 1V9K A; 5LMN D; 5FLX E; 2ZM6 D; 3HJW A; 1HNZ D; 4X62 D; 2APO A; 1XMO D; 4B3T D; 4DV1 D; 2AUS A; 1H3F A; 4OUD A; 4K0K D; 4JV5 D; #chains in the Genus database with same CATH homology 1XNQ D; 4JI5 D; 4DR2 D; 2UUA D; 4LF7 D; 4YY3 D; 2JAN A; 4DV0 D; 4LF9 D; 3LWV A; 3HAX A; 4DV2 D; 1HNW D; 4DV7 D; 4JI1 D; 4B3S D; 1P9K A; 3T1Y D; 4DR5 D; 1HR0 D; 3T1H D; 3HJY A; 3OTO D; 1N32 D; 2UUC D; 1N33 D; 4JI6 D; 1KSV A; 3LWP A; 2AB4 A; 4JYA D; 4LGT A; 2I82 A; 4JI0 D; 2IST A; 2E5L D; 4DR3 D; 3LWQ A; 1IBL D; 1ZL3 A; 4X66 D; 1XMQ D; 2UUB D; 4X64 D; 4DV3 D; 1I94 D; 4JI4 D; 4LF4 D; 4DR7 D; 1C05 A; 5BR8 D; 2HVY A; 4LFC D; 1JH3 A; 4DV4 D; 1SZW A; 1XNR D; 4X65 D; 2UXC D; 3KBG A; 4LF5 D; 1PRZ A; 4NXM D; 1R3F A; 4LF8 D; 1SGV A; 5LMU D; 4DV6 D; 4DUZ D; 4NXN D; 4JI7 D; 1C06 A; 5IWA D; 4GKJ D; 1V9F A; 1R3E A; 4DUY D; 2RFK A; 4OX9 D; 4DR4 D; 1KSL A; 1XPI A; 3UAI A; 3LWR A; 2K6P A; 1HNX D; 2HHH D; 4B3M D; 2VQE D; 4GKK D; 4DR6 D; 1QYU A; 3HP7 A; 1DM9 A; 1FJG D; 1IBK D; 1ZE2 A; 1KSK A; 1J5E D; 1FKA D; 4JI8 D; 3LWO A; 2EY4 A; 4LAB A; 2KTL A; 2F4V D; 1SI7 A; 4JI3 D; 4LF6 D; 4DV5 D; 2UXD D; 4YHH D; 4LFA D; 4B3R D; 2UXB D; 1SB7 A; 1N36 D; 3U28 A; 4DR1 D; 1N34 D; 3MQK A; 2VQF D; 4LFB D; 1K8W A; 1H3E A; 2UU9 D; 3DH3 A; 4JI2 D; 1Z2Z A; 1VIO A; 4KHP D; 1ZE1 A; 1IBM D; 4AQY D; 1V9K A; 5LMN D; 2ZM6 D; 3HJW A; 1HNZ D; 4X62 D; 2APO A; 1XMO D; 4B3T D; 4DV1 D; 2AUS A; 1H3F A; 4OUD A; 4K0K D; 4JV5 D;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
