1CFYA

Yeast cofilin, monoclinic crystal form
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
133
structure length
133
Chain Sequence
VAVADESLTAFNDLKLGKKYKFILFGLNDAKTEIVVKETSTDPSYDAFLEKLPENDCLYAIYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSTDVQGTDFSEVSYDSVLERVSR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure determination of yeast cofilin.
pubmed doi rcsb
molecule tags Actin-binding protein
source organism Saccharomyces cerevisiae
molecule keywords COFILIN
total genus 38
structure length 133
sequence length 133
chains with identical sequence B
ec nomenclature
pdb deposition date 1996-11-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00241 Cofilin_ADF Cofilin/tropomyosin-type actin-binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 1cfyA00
1NLVG 1NMDG 3FFKA 3CI5G 4CBXG 1WFSA 3EG9A 4KEDA 2HD7A 4BEX1 3CJBG 1T3YA 2FF3A 2NUPA 1PCXA 5FAFA 4PKHB 1PD1A 5KYYB 1VFQA 3Q2BA 5KYNA 1HQZ1 3FG6A 3EG9B 2L72A 5L6WC 2FH2A 1M4JA 5KYYA 1T2LA 5KYXB 2NUPB 1MDUA 2W0IA 3L50A 2QTVA 1PD0A 1X67A 3A5NS 1KCQA 4Z94G 1SVRA 2KVKA 2MV2A 2FH1A 2LJ8A 1P8XA 5KYXA 1RGIG 1VKKA 4KEEA 1TVJA 4PKGG 3EGXA 2D8BA 1C0GS 1JHWA 2XF1A 4S10C 1COFA 3EFOB 1SVQA 1YVNG 1WM4A 3A5LS 5IVUA 1C0FS 1Q8GA 2NUTB 2VILA 5KYUB 3A5MS 3A5OS 5DD2A 3TU5B 3EFOA 3CJCG 1F7SA 1M2VA 1AK7A 1T44G 1Q8XA 3EGXB 2NUTA 2VIKA 2FF6G 5KYWB 1DEJS 2LLFA 1M2OA 1TMWA 4CBWG 5KYUA 4CBUG 1D4XG 5HVKD 1D0NA 1J72A 1YAGG 3EH2A 4KEFA 2MP4A 2MOTA 5KYWA 1AK6A 1T3XA 5A1MA 2XFAA 1ESVS 1M2VB 1AHQA 2FGHA 1NM1G 3EGDB 4LIZA 1H1VG 1P8ZG 5HVKB 1EQYS 1V6FA 3EGDA 5FAEA 2I2QA 3CIPG 1NPHA 3DAWB 2FH3A 3FG7A 4PKIG 1WNJA 1CFYA 1SVYA 3EH1A 2FH4A 3FFNA 1UDMA 1QPVA 4JD2H 2VACA 2LXXA 1CNUA
chains in the Genus database with same CATH superfamily
1NLVG 1NMDG 3FFKA 3CI5G 4CBXG 1WFSA 3EG9A 4KEDA 2HD7A 4BEX1 3CJBG 1T3YA 2FF3A 2NUPA 1PCXA 5FAFA 4PKHB 1PD1A 5KYYB 1VFQA 3Q2BA 5KYNA 1HQZ1 3FG6A 3EG9B 2L72A 5L6WC 2FH2A 1M4JA 5KYYA 1T2LA 5KYXB 2NUPB 1MDUA 2W0IA 3L50A 2QTVA 1PD0A 1X67A 3A5NS 1KCQA 4Z94G 1SVRA 2KVKA 2MV2A 2FH1A 2LJ8A 1P8XA 5KYXA 1RGIG 1VKKA 4KEEA 1TVJA 4PKGG 3EGXA 2D8BA 1C0GS 1JHWA 2XF1A 4S10C 1COFA 3EFOB 1SVQA 1YVNG 1WM4A 3DA7A 3A5LS 5IVUA 1C0FS 1Q8GA 2NUTB 2VILA 5KYUB 3A5MS 3A5OS 5DD2A 3TU5B 3EFOA 3CJCG 1F7SA 1M2VA 1AK7A 1T44G 1Q8XA 3EGXB 2NUTA 2VIKA 2FF6G 5KYWB 1DEJS 2LLFA 1M2OA 1TMWA 4CBWG 5KYUA 4CBUG 1D4XG 5HVKD 1D0NA 1J72A 1YAGG 3EH2A 4KEFA 2MP4A 2MOTA 5KYWA 1AK6A 1T3XA 5A1MA 2XFAA 1ESVS 1M2VB 1AHQA 2FGHA 1NM1G 3EGDB 4LIZA 1H1VG 1P8ZG 5HVKB 1EQYS 1V6FA 3EGDA 5FAEA 2I2QA 3CIPG 1NPHA 3DAWB 2FH3A 3FG7A 4PKIG 1WNJA 1CFYA 1SVYA 3EH1A 2FH4A 3FFNA 1UDMA 1QPVA 4JD2H 2VACA 2LXXA 1CNUA
chains in the Genus database with same CATH topology
1NLVG 1NMDG 3FFKA 3CI5G 4CBXG 1WFSA 3EG9A 4KEDA 2HD7A 4BEX1 3CJBG 1T3YA 2FF3A 2NUPA 1PCXA 5FAFA 4PKHB 1PD1A 5KYYB 1VFQA 3Q2BA 5KYNA 1HQZ1 3FG6A 3EG9B 2L72A 5L6WC 2FH2A 1M4JA 5KYYA 1T2LA 5KYXB 2NUPB 1MDUA 2W0IA 3L50A 2QTVA 1PD0A 1X67A 3A5NS 1KCQA 4Z94G 1SVRA 2KVKA 2MV2A 2FH1A 2LJ8A 1P8XA 5KYXA 1RGIG 1VKKA 4KEEA 1TVJA 4PKGG 3EGXA 2D8BA 1C0GS 1JHWA 2XF1A 4S10C 1COFA 3EFOB 1SVQA 1YVNG 1WM4A 3DA7A 3A5LS 5IVUA 1C0FS 1Q8GA 2NUTB 2VILA 5KYUB 3A5MS 3A5OS 5DD2A 3TU5B 3EFOA 3CJCG 1F7SA 1M2VA 1AK7A 1T44G 1Q8XA 3EGXB 2NUTA 2VIKA 2FF6G 5KYWB 1DEJS 2LLFA 1M2OA 1TMWA 4CBWG 5KYUA 4CBUG 1D4XG 5HVKD 1D0NA 1J72A 1YAGG 3EH2A 4KEFA 2MP4A 2MOTA 5KYWA 1AK6A 1T3XA 5A1MA 2XFAA 1ESVS 1M2VB 1AHQA 2FGHA 1NM1G 3EGDB 4LIZA 1H1VG 1P8ZG 5HVKB 1EQYS 1V6FA 3EGDA 5FAEA 2I2QA 3CIPG 1NPHA 3DAWB 2FH3A 3FG7A 4PKIG 1WNJA 1CFYA 1SVYA 3EH1A 2FH4A 3FFNA 1UDMA 1QPVA 4JD2H 2VACA 2LXXA 1CNUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1NLV G;  1NMD G;  3FFK A;  3CI5 G;  4CBX G;  1WFS A;  3EG9 A;  4KED A;  2HD7 A;  4BEX 1;  3CJB G;  1T3Y A;  2FF3 A;  2NUP A;  1PCX A;  5FAF A;  4PKH B;  1PD1 A;  5KYY B;  1VFQ A;  3Q2B A;  5KYN A;  1HQZ 1;  3FG6 A;  3EG9 B;  2L72 A;  5L6W C;  2FH2 A;  1M4J A;  5KYY A;  1T2L A;  5KYX B;  2NUP B;  1MDU A;  2W0I A;  3L50 A;  2QTV A;  1PD0 A;  1X67 A;  3A5N S;  1KCQ A;  4Z94 G;  1SVR A;  2KVK A;  2MV2 A;  2FH1 A;  2LJ8 A;  1P8X A;  5KYX A;  1RGI G;  1VKK A;  4KEE A;  1TVJ A;  4PKG G;  3EGX A;  2D8B A;  1C0G S;  1JHW A;  2XF1 A;  4S10 C;  1COF A;  3EFO B;  1SVQ A;  1YVN G;  1WM4 A;  3A5L S;  5IVU A;  1C0F S;  1Q8G A;  2NUT B;  2VIL A;  5KYU B;  3A5M S;  3A5O S;  5DD2 A;  3TU5 B;  3EFO A;  3CJC G;  1F7S A;  1M2V A;  1AK7 A;  1T44 G;  1Q8X A;  3EGX B;  2NUT A;  2VIK A;  2FF6 G;  5KYW B;  1DEJ S;  2LLF A;  1M2O A;  1TMW A;  4CBW G;  5KYU A;  4CBU G;  1D4X G;  5HVK D;  1D0N A;  1J72 A;  1YAG G;  3EH2 A;  4KEF A;  2MP4 A;  2MOT A;  5KYW A;  1AK6 A;  1T3X A;  5A1M A;  2XFA A;  1ESV S;  1M2V B;  1AHQ A;  2FGH A;  1NM1 G;  3EGD B;  4LIZ A;  1H1V G;  1P8Z G;  5HVK B;  1EQY S;  1V6F A;  3EGD A;  5FAE A;  2I2Q A;  3CIP G;  1NPH A;  3DAW B;  2FH3 A;  3FG7 A;  4PKI G;  1WNJ A;  1CFY A;  1SVY A;  3EH1 A;  2FH4 A;  3FFN A;  1UDM A;  1QPV A;  4JD2 H;  2VAC A;  2LXX A;  1CNU A; 
#chains in the Genus database with same CATH topology
 1NLV G;  1NMD G;  3FFK A;  3CI5 G;  4CBX G;  1WFS A;  3EG9 A;  4KED A;  2HD7 A;  4BEX 1;  3CJB G;  1T3Y A;  2FF3 A;  2NUP A;  1PCX A;  5FAF A;  4PKH B;  1PD1 A;  5KYY B;  1VFQ A;  3Q2B A;  5KYN A;  1HQZ 1;  3FG6 A;  3EG9 B;  2L72 A;  5L6W C;  2FH2 A;  1M4J A;  5KYY A;  1T2L A;  5KYX B;  2NUP B;  1MDU A;  2W0I A;  3L50 A;  2QTV A;  1PD0 A;  1X67 A;  3A5N S;  1KCQ A;  4Z94 G;  1SVR A;  2KVK A;  2MV2 A;  2FH1 A;  2LJ8 A;  1P8X A;  5KYX A;  1RGI G;  1VKK A;  4KEE A;  1TVJ A;  4PKG G;  3EGX A;  2D8B A;  1C0G S;  1JHW A;  2XF1 A;  4S10 C;  1COF A;  3EFO B;  1SVQ A;  1YVN G;  1WM4 A;  3DA7 A;  3A5L S;  5IVU A;  1C0F S;  1Q8G A;  2NUT B;  2VIL A;  5KYU B;  3A5M S;  3A5O S;  5DD2 A;  3TU5 B;  3EFO A;  3CJC G;  1F7S A;  1M2V A;  1AK7 A;  1T44 G;  1Q8X A;  3EGX B;  2NUT A;  2VIK A;  2FF6 G;  5KYW B;  1DEJ S;  2LLF A;  1M2O A;  1TMW A;  4CBW G;  5KYU A;  4CBU G;  1D4X G;  5HVK D;  1D0N A;  1J72 A;  1YAG G;  3EH2 A;  4KEF A;  2MP4 A;  2MOT A;  5KYW A;  1AK6 A;  1T3X A;  5A1M A;  2XFA A;  1ESV S;  1M2V B;  1AHQ A;  2FGH A;  1NM1 G;  3EGD B;  4LIZ A;  1H1V G;  1P8Z G;  5HVK B;  1EQY S;  1V6F A;  3EGD A;  5FAE A;  2I2Q A;  3CIP G;  1NPH A;  3DAW B;  2FH3 A;  3FG7 A;  4PKI G;  1WNJ A;  1CFY A;  1SVY A;  3EH1 A;  2FH4 A;  3FFN A;  1UDM A;  1QPV A;  4JD2 H;  2VAC A;  2LXX A;  1CNU A; 
#chains in the Genus database with same CATH homology
 1NLV G;  1NMD G;  3FFK A;  3CI5 G;  4CBX G;  1WFS A;  3EG9 A;  4KED A;  2HD7 A;  4BEX 1;  3CJB G;  1T3Y A;  2FF3 A;  2NUP A;  1PCX A;  5FAF A;  4PKH B;  1PD1 A;  5KYY B;  1VFQ A;  3Q2B A;  5KYN A;  1HQZ 1;  3FG6 A;  3EG9 B;  2L72 A;  5L6W C;  2FH2 A;  1M4J A;  5KYY A;  1T2L A;  5KYX B;  2NUP B;  1MDU A;  2W0I A;  3L50 A;  2QTV A;  1PD0 A;  1X67 A;  3A5N S;  1KCQ A;  4Z94 G;  1SVR A;  2KVK A;  2MV2 A;  2FH1 A;  2LJ8 A;  1P8X A;  5KYX A;  1RGI G;  1VKK A;  4KEE A;  1TVJ A;  4PKG G;  3EGX A;  2D8B A;  1C0G S;  1JHW A;  2XF1 A;  4S10 C;  1COF A;  3EFO B;  1SVQ A;  1YVN G;  1WM4 A;  3DA7 A;  3A5L S;  5IVU A;  1C0F S;  1Q8G A;  2NUT B;  2VIL A;  5KYU B;  3A5M S;  3A5O S;  5DD2 A;  3TU5 B;  3EFO A;  3CJC G;  1F7S A;  1M2V A;  1AK7 A;  1T44 G;  1Q8X A;  3EGX B;  2NUT A;  2VIK A;  2FF6 G;  5KYW B;  1DEJ S;  2LLF A;  1M2O A;  1TMW A;  4CBW G;  5KYU A;  4CBU G;  1D4X G;  5HVK D;  1D0N A;  1J72 A;  1YAG G;  3EH2 A;  4KEF A;  2MP4 A;  2MOT A;  5KYW A;  1AK6 A;  1T3X A;  5A1M A;  2XFA A;  1ESV S;  1M2V B;  1AHQ A;  2FGH A;  1NM1 G;  3EGD B;  4LIZ A;  1H1V G;  1P8Z G;  5HVK B;  1EQY S;  1V6F A;  3EGD A;  5FAE A;  2I2Q A;  3CIP G;  1NPH A;  3DAW B;  2FH3 A;  3FG7 A;  4PKI G;  1WNJ A;  1CFY A;  1SVY A;  3EH1 A;  2FH4 A;  3FFN A;  1UDM A;  1QPV A;  4JD2 H;  2VAC A;  2LXX A;  1CNU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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