1JHWA

Ca2+-binding mimicry in the crystal structure of the eu3+-bound mutant human macrophage capping protein cap g
Total Genus 78
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
78
sequence length
336
structure length
326
Chain Sequence
PFPGSVQDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEEVSHLHLWIGQQSSRDEQGACAVLAVQLDDYLGGRPVQHREVQGNESDLFMSYFPRGLKYQEGGVESGFKHVVPNEVVVQRLYQVKGAKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPAEMIQVLGPKPALKEGNPAQAAALYKVSDATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIYIWKGRKANEKERQAALQVAEGFISRMQYAPNTQVEILPQGRESPIFKQFFKDW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords MACROPHAGE CAPPING PROTEIN
publication title Crystal Structure of Mutant Human Macrophage Capping Protein
rcsb
source organism Homo sapiens
molecule tags Structural protein
total genus 78
structure length 326
sequence length 336
ec nomenclature
pdb deposition date 2001-06-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00626 Gelsolin Gelsolin repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 1jhwA02
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 1jhwA03
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 1jhwA01
1TMWA 2MV2A 3CJBG 1V6FA 1WFSA 1COFA 1YAGG 4LIZA 5KYNA 1AHQA 1D4XG 4Z94G 5FAFA 5KYUB 3CI5G 5KYWA 5IVUA 2KVKA 3CIPG 1F7SA 4S10C 3EGXB 1ESVS 2NUTA 4PKGG 5L6WC 1HQZ1 1YVNG 1P8ZG 3DAWB 2FH2A 1H1VG 3FFKA 4PKHB 2NUTB 1VKKA 1KCQA 5DD2A 2VIKA 2HD7A 1PCXA 1WM4A 3FG7A 1D0NA 1X67A 4CBUG 1AK6A 2FF3A 1DEJS 2FH3A 3A5MS 3TU5B 2L72A 1NLVG 1NMDG 2MP4A 1C0FS 2QTVA 1RGIG 3EG9A 1UDMA 5KYYA 2FH1A 2W0IA 3Q2BA 2FH4A 1C0GS 1MDUA 1J72A 5HVKB 1T2LA 1WNJA 1M2VA 2MOTA 3EG9B 5KYWB 2LLFA 1SVQA 2NUPA 1JHWA 5KYYB 3CJCG 4PKIG 3FFNA 2VACA 1Q8XA 2NUPB 3EFOA 1VFQA 1T3XA 2XFAA 1NPHA 3EFOB 1TVJA 2FGHA 2I2QA 2LXXA 2VILA 2D8BA 1CNUA 1P8XA 3A5LS 5FAEA 4KEEA 1SVYA 4JD2H 1CFYA 1T44G 5KYUA 2LJ8A 3A5NS 3EGDA 4KEFA 5HVKD 2XF1A 4BEX1 1AK7A 5KYXA 1M2VB 4CBWG 3EGXA 5A1MA 1M4JA 1T3YA 1PD1A 2FF6G 1EQYS 3EGDB 1NM1G 3L50A 4CBXG 3A5OS 3EH2A 1SVRA 3EH1A 5KYXB 4KEDA 1PD0A 1Q8GA 3FG6A 1QPVA 1M2OA
chains in the Genus database with same CATH superfamily
1TMWA 2MV2A 3CJBG 1V6FA 1WFSA 1COFA 1YAGG 4LIZA 5KYNA 1AHQA 1D4XG 4Z94G 5FAFA 5KYUB 3CI5G 5KYWA 5IVUA 2KVKA 3CIPG 3DA7A 1F7SA 4S10C 3EGXB 1ESVS 2NUTA 4PKGG 5L6WC 1HQZ1 1YVNG 1P8ZG 3DAWB 2FH2A 1H1VG 3FFKA 4PKHB 2NUTB 1VKKA 1KCQA 5DD2A 2VIKA 2HD7A 1PCXA 1WM4A 3FG7A 1D0NA 1X67A 4CBUG 1AK6A 2FF3A 1DEJS 2FH3A 3A5MS 3TU5B 2L72A 1NLVG 1NMDG 2MP4A 1C0FS 2QTVA 1RGIG 3EG9A 1UDMA 5KYYA 2FH1A 2W0IA 3Q2BA 2FH4A 1C0GS 1MDUA 1J72A 5HVKB 1T2LA 1WNJA 1M2VA 2MOTA 3EG9B 5KYWB 2LLFA 1SVQA 2NUPA 1JHWA 5KYYB 3CJCG 4PKIG 3FFNA 2VACA 1Q8XA 2NUPB 3EFOA 1VFQA 1T3XA 2XFAA 1NPHA 3EFOB 1TVJA 2FGHA 2I2QA 2LXXA 2VILA 2D8BA 1CNUA 1P8XA 3A5LS 5FAEA 4KEEA 1SVYA 4JD2H 1CFYA 1T44G 5KYUA 2LJ8A 3A5NS 3EGDA 4KEFA 5HVKD 2XF1A 4BEX1 1AK7A 5KYXA 1M2VB 4CBWG 3EGXA 5A1MA 1M4JA 1T3YA 1PD1A 2FF6G 1EQYS 3EGDB 1NM1G 3L50A 4CBXG 3A5OS 3EH2A 1SVRA 3EH1A 5KYXB 4KEDA 1PD0A 1Q8GA 3FG6A 1QPVA 1M2OA
chains in the Genus database with same CATH topology
1TMWA 2MV2A 3CJBG 1V6FA 1WFSA 1COFA 1YAGG 4LIZA 5KYNA 1AHQA 1D4XG 4Z94G 5FAFA 5KYUB 3CI5G 5KYWA 5IVUA 2KVKA 3CIPG 3DA7A 1F7SA 4S10C 3EGXB 1ESVS 2NUTA 4PKGG 5L6WC 1HQZ1 1YVNG 1P8ZG 3DAWB 2FH2A 1H1VG 3FFKA 4PKHB 2NUTB 1VKKA 1KCQA 5DD2A 2VIKA 2HD7A 1PCXA 1WM4A 3FG7A 1D0NA 1X67A 4CBUG 1AK6A 2FF3A 1DEJS 2FH3A 3A5MS 3TU5B 2L72A 1NLVG 1NMDG 2MP4A 1C0FS 2QTVA 1RGIG 3EG9A 1UDMA 5KYYA 2FH1A 2W0IA 3Q2BA 2FH4A 1C0GS 1MDUA 1J72A 5HVKB 1T2LA 1WNJA 1M2VA 2MOTA 3EG9B 5KYWB 2LLFA 1SVQA 2NUPA 1JHWA 5KYYB 3CJCG 4PKIG 3FFNA 2VACA 1Q8XA 2NUPB 3EFOA 1VFQA 1T3XA 2XFAA 1NPHA 3EFOB 1TVJA 2FGHA 2I2QA 2LXXA 2VILA 2D8BA 1CNUA 1P8XA 3A5LS 5FAEA 4KEEA 1SVYA 4JD2H 1CFYA 1T44G 5KYUA 2LJ8A 3A5NS 3EGDA 4KEFA 5HVKD 2XF1A 4BEX1 1AK7A 5KYXA 1M2VB 4CBWG 3EGXA 5A1MA 1M4JA 1T3YA 1PD1A 2FF6G 1EQYS 3EGDB 1NM1G 3L50A 4CBXG 3A5OS 3EH2A 1SVRA 3EH1A 5KYXB 4KEDA 1PD0A 1Q8GA 3FG6A 1QPVA 1M2OA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TMW A;  2MV2 A;  3CJB G;  1V6F A;  1WFS A;  1COF A;  1YAG G;  4LIZ A;  5KYN A;  1AHQ A;  1D4X G;  4Z94 G;  5FAF A;  5KYU B;  3CI5 G;  5KYW A;  5IVU A;  2KVK A;  3CIP G;  1F7S A;  4S10 C;  3EGX B;  1ESV S;  2NUT A;  4PKG G;  5L6W C;  1HQZ 1;  1YVN G;  1P8Z G;  3DAW B;  2FH2 A;  1H1V G;  3FFK A;  4PKH B;  2NUT B;  1VKK A;  1KCQ A;  5DD2 A;  2VIK A;  2HD7 A;  1PCX A;  1WM4 A;  3FG7 A;  1D0N A;  1X67 A;  4CBU G;  1AK6 A;  2FF3 A;  1DEJ S;  2FH3 A;  3A5M S;  3TU5 B;  2L72 A;  1NLV G;  1NMD G;  2MP4 A;  1C0F S;  2QTV A;  1RGI G;  3EG9 A;  1UDM A;  5KYY A;  2FH1 A;  2W0I A;  3Q2B A;  2FH4 A;  1C0G S;  1MDU A;  1J72 A;  5HVK B;  1T2L A;  1WNJ A;  1M2V A;  2MOT A;  3EG9 B;  5KYW B;  2LLF A;  1SVQ A;  2NUP A;  1JHW A;  5KYY B;  3CJC G;  4PKI G;  3FFN A;  2VAC A;  1Q8X A;  2NUP B;  3EFO A;  1VFQ A;  1T3X A;  2XFA A;  1NPH A;  3EFO B;  1TVJ A;  2FGH A;  2I2Q A;  2LXX A;  2VIL A;  2D8B A;  1CNU A;  1P8X A;  3A5L S;  5FAE A;  4KEE A;  1SVY A;  4JD2 H;  1CFY A;  1T44 G;  5KYU A;  2LJ8 A;  3A5N S;  3EGD A;  4KEF A;  5HVK D;  2XF1 A;  4BEX 1;  1AK7 A;  5KYX A;  1M2V B;  4CBW G;  3EGX A;  5A1M A;  1M4J A;  1T3Y A;  1PD1 A;  2FF6 G;  1EQY S;  3EGD B;  1NM1 G;  3L50 A;  4CBX G;  3A5O S;  3EH2 A;  1SVR A;  3EH1 A;  5KYX B;  4KED A;  1PD0 A;  1Q8G A;  3FG6 A;  1QPV A;  1M2O A; 
#chains in the Genus database with same CATH topology
 1TMW A;  2MV2 A;  3CJB G;  1V6F A;  1WFS A;  1COF A;  1YAG G;  4LIZ A;  5KYN A;  1AHQ A;  1D4X G;  4Z94 G;  5FAF A;  5KYU B;  3CI5 G;  5KYW A;  5IVU A;  2KVK A;  3CIP G;  3DA7 A;  1F7S A;  4S10 C;  3EGX B;  1ESV S;  2NUT A;  4PKG G;  5L6W C;  1HQZ 1;  1YVN G;  1P8Z G;  3DAW B;  2FH2 A;  1H1V G;  3FFK A;  4PKH B;  2NUT B;  1VKK A;  1KCQ A;  5DD2 A;  2VIK A;  2HD7 A;  1PCX A;  1WM4 A;  3FG7 A;  1D0N A;  1X67 A;  4CBU G;  1AK6 A;  2FF3 A;  1DEJ S;  2FH3 A;  3A5M S;  3TU5 B;  2L72 A;  1NLV G;  1NMD G;  2MP4 A;  1C0F S;  2QTV A;  1RGI G;  3EG9 A;  1UDM A;  5KYY A;  2FH1 A;  2W0I A;  3Q2B A;  2FH4 A;  1C0G S;  1MDU A;  1J72 A;  5HVK B;  1T2L A;  1WNJ A;  1M2V A;  2MOT A;  3EG9 B;  5KYW B;  2LLF A;  1SVQ A;  2NUP A;  1JHW A;  5KYY B;  3CJC G;  4PKI G;  3FFN A;  2VAC A;  1Q8X A;  2NUP B;  3EFO A;  1VFQ A;  1T3X A;  2XFA A;  1NPH A;  3EFO B;  1TVJ A;  2FGH A;  2I2Q A;  2LXX A;  2VIL A;  2D8B A;  1CNU A;  1P8X A;  3A5L S;  5FAE A;  4KEE A;  1SVY A;  4JD2 H;  1CFY A;  1T44 G;  5KYU A;  2LJ8 A;  3A5N S;  3EGD A;  4KEF A;  5HVK D;  2XF1 A;  4BEX 1;  1AK7 A;  5KYX A;  1M2V B;  4CBW G;  3EGX A;  5A1M A;  1M4J A;  1T3Y A;  1PD1 A;  2FF6 G;  1EQY S;  3EGD B;  1NM1 G;  3L50 A;  4CBX G;  3A5O S;  3EH2 A;  1SVR A;  3EH1 A;  5KYX B;  4KED A;  1PD0 A;  1Q8G A;  3FG6 A;  1QPV A;  1M2O A; 
#chains in the Genus database with same CATH homology
 1TMW A;  2MV2 A;  3CJB G;  1V6F A;  1WFS A;  1COF A;  1YAG G;  4LIZ A;  5KYN A;  1AHQ A;  1D4X G;  4Z94 G;  5FAF A;  5KYU B;  3CI5 G;  5KYW A;  5IVU A;  2KVK A;  3CIP G;  3DA7 A;  1F7S A;  4S10 C;  3EGX B;  1ESV S;  2NUT A;  4PKG G;  5L6W C;  1HQZ 1;  1YVN G;  1P8Z G;  3DAW B;  2FH2 A;  1H1V G;  3FFK A;  4PKH B;  2NUT B;  1VKK A;  1KCQ A;  5DD2 A;  2VIK A;  2HD7 A;  1PCX A;  1WM4 A;  3FG7 A;  1D0N A;  1X67 A;  4CBU G;  1AK6 A;  2FF3 A;  1DEJ S;  2FH3 A;  3A5M S;  3TU5 B;  2L72 A;  1NLV G;  1NMD G;  2MP4 A;  1C0F S;  2QTV A;  1RGI G;  3EG9 A;  1UDM A;  5KYY A;  2FH1 A;  2W0I A;  3Q2B A;  2FH4 A;  1C0G S;  1MDU A;  1J72 A;  5HVK B;  1T2L A;  1WNJ A;  1M2V A;  2MOT A;  3EG9 B;  5KYW B;  2LLF A;  1SVQ A;  2NUP A;  1JHW A;  5KYY B;  3CJC G;  4PKI G;  3FFN A;  2VAC A;  1Q8X A;  2NUP B;  3EFO A;  1VFQ A;  1T3X A;  2XFA A;  1NPH A;  3EFO B;  1TVJ A;  2FGH A;  2I2Q A;  2LXX A;  2VIL A;  2D8B A;  1CNU A;  1P8X A;  3A5L S;  5FAE A;  4KEE A;  1SVY A;  4JD2 H;  1CFY A;  1T44 G;  5KYU A;  2LJ8 A;  3A5N S;  3EGD A;  4KEF A;  5HVK D;  2XF1 A;  4BEX 1;  1AK7 A;  5KYX A;  1M2V B;  4CBW G;  3EGX A;  5A1M A;  1M4J A;  1T3Y A;  1PD1 A;  2FF6 G;  1EQY S;  3EGD B;  1NM1 G;  3L50 A;  4CBX G;  3A5O S;  3EH2 A;  1SVR A;  3EH1 A;  5KYX B;  4KED A;  1PD0 A;  1Q8G A;  3FG6 A;  1QPV A;  1M2O A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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