1JHWA

Ca2+-binding mimicry in the crystal structure of the eu3+-bound mutant human macrophage capping protein cap g
Total Genus 78
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
78
sequence length
336
structure length
326
Chain Sequence
PFPGSVQDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEEVSHLHLWIGQQSSRDEQGACAVLAVQLDDYLGGRPVQHREVQGNESDLFMSYFPRGLKYQEGGVESGFKHVVPNEVVVQRLYQVKGAKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPAEMIQVLGPKPALKEGNPAQAAALYKVSDATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIYIWKGRKANEKERQAALQVAEGFISRMQYAPNTQVEILPQGRESPIFKQFFKDW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of Mutant Human Macrophage Capping Protein
rcsb
molecule tags Structural protein
source organism Homo sapiens
molecule keywords MACROPHAGE CAPPING PROTEIN
total genus 78
structure length 326
sequence length 336
ec nomenclature
pdb deposition date 2001-06-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00626 Gelsolin Gelsolin repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 1jhwA02
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 1jhwA03
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 1jhwA01
3FG6A 4S10C 1T44G 4Z94G 2LLFA 1J72A 1NLVG 1P8XA 2FGHA 3FG7A 5KYWA 1VKKA 1ESVS 2D8BA 3EGXA 4PKGG 5KYWB 1SVQA 1PD0A 1D0NA 1C0FS 3EGXB 1Q8GA 2FH1A 2MOTA 1YVNG 3CJCG 4BEX1 3EH2A 4PKIG 5L6WC 5FAEA 1T3XA 1C0GS 3EH1A 2HD7A 3CI5G 4CBUG 2FH3A 1DEJS 1PCXA 2MV2A 5A1MA 1X67A 1EQYS 1KCQA 1QPVA 1JHWA 1NPHA 3A5MS 2LXXA 1M2OA 1TMWA 5KYNA 1YAGG 3EG9B 1F7SA 5HVKD 1SVYA 1NMDG 1NM1G 1WFSA 3FFNA 4JD2H 4CBXG 2FF6G 3A5NS 4PKHB 2L72A 1SVRA 1M2VA 2QTVA 1AK7A 3EGDB 1COFA 1M2VB 3A5LS 3Q2BA 4KEDA 4KEEA 1RGIG 1P8ZG 1UDMA 1HQZ1 3EG9A 3EFOA 5KYXB 1D4XG 1VFQA 3EFOB 1M4JA 1AK6A 2FF3A 1WNJA 1CNUA 2NUTA 2VILA 3L50A 2NUTB 2VACA 1Q8XA 1AHQA 4LIZA 1T3YA 2NUPA 5DD2A 2LJ8A 3EGDA 2MP4A 2XFAA 3A5OS 5KYUA 2NUPB 2KVKA 3CIPG 2XF1A 5FAFA 2VIKA 5IVUA 2I2QA 4CBWG 1MDUA 5KYUB 4KEFA 1TVJA 1T2LA 1PD1A 5KYXA 5HVKB 2FH4A 1H1VG 2FH2A 1V6FA 2W0IA 3DAWB 3TU5B 5KYYA 3FFKA 1WM4A 3CJBG 1CFYA 5KYYB
chains in the Genus database with same CATH superfamily
3FG6A 4S10C 1T44G 4Z94G 2LLFA 1J72A 1NLVG 1P8XA 2FGHA 3FG7A 5KYWA 1VKKA 1ESVS 2D8BA 3EGXA 4PKGG 5KYWB 1SVQA 1PD0A 1D0NA 1C0FS 3EGXB 1Q8GA 2FH1A 2MOTA 1YVNG 3CJCG 4BEX1 3EH2A 4PKIG 5L6WC 5FAEA 1T3XA 3DA7A 1C0GS 3EH1A 2HD7A 3CI5G 4CBUG 2FH3A 1DEJS 1PCXA 2MV2A 5A1MA 1X67A 1EQYS 1KCQA 1QPVA 1JHWA 1NPHA 3A5MS 2LXXA 1M2OA 1TMWA 5KYNA 1YAGG 3EG9B 1F7SA 5HVKD 1SVYA 1NMDG 1NM1G 1WFSA 3FFNA 4JD2H 4CBXG 2FF6G 3A5NS 4PKHB 2L72A 1SVRA 1M2VA 2QTVA 1AK7A 3EGDB 1COFA 1M2VB 3A5LS 3Q2BA 4KEDA 4KEEA 1RGIG 1P8ZG 1UDMA 1HQZ1 3EG9A 3EFOA 5KYXB 1D4XG 1VFQA 3EFOB 1M4JA 1AK6A 2FF3A 1WNJA 1CNUA 2NUTA 2VILA 3L50A 2NUTB 2VACA 1Q8XA 1AHQA 4LIZA 1T3YA 2NUPA 5DD2A 2LJ8A 3EGDA 2MP4A 2XFAA 3A5OS 5KYUA 2NUPB 2KVKA 3CIPG 2XF1A 5FAFA 2VIKA 5IVUA 2I2QA 4CBWG 1MDUA 5KYUB 4KEFA 1TVJA 1T2LA 1PD1A 5KYXA 5HVKB 2FH4A 1H1VG 2FH2A 1V6FA 2W0IA 3DAWB 3TU5B 5KYYA 3FFKA 1WM4A 3CJBG 1CFYA 5KYYB
chains in the Genus database with same CATH topology
3FG6A 4S10C 1T44G 4Z94G 2LLFA 1J72A 1NLVG 1P8XA 2FGHA 3FG7A 5KYWA 1VKKA 1ESVS 2D8BA 3EGXA 4PKGG 5KYWB 1SVQA 1PD0A 1D0NA 1C0FS 3EGXB 1Q8GA 2FH1A 2MOTA 1YVNG 3CJCG 4BEX1 3EH2A 4PKIG 5L6WC 5FAEA 1T3XA 3DA7A 1C0GS 3EH1A 2HD7A 3CI5G 4CBUG 2FH3A 1DEJS 1PCXA 2MV2A 5A1MA 1X67A 1EQYS 1KCQA 1QPVA 1JHWA 1NPHA 3A5MS 2LXXA 1M2OA 1TMWA 5KYNA 1YAGG 3EG9B 1F7SA 5HVKD 1SVYA 1NMDG 1NM1G 1WFSA 3FFNA 4JD2H 4CBXG 2FF6G 3A5NS 4PKHB 2L72A 1SVRA 1M2VA 2QTVA 1AK7A 3EGDB 1COFA 1M2VB 3A5LS 3Q2BA 4KEDA 4KEEA 1RGIG 1P8ZG 1UDMA 1HQZ1 3EG9A 3EFOA 5KYXB 1D4XG 1VFQA 3EFOB 1M4JA 1AK6A 2FF3A 1WNJA 1CNUA 2NUTA 2VILA 3L50A 2NUTB 2VACA 1Q8XA 1AHQA 4LIZA 1T3YA 2NUPA 5DD2A 2LJ8A 3EGDA 2MP4A 2XFAA 3A5OS 5KYUA 2NUPB 2KVKA 3CIPG 2XF1A 5FAFA 2VIKA 5IVUA 2I2QA 4CBWG 1MDUA 5KYUB 4KEFA 1TVJA 1T2LA 1PD1A 5KYXA 5HVKB 2FH4A 1H1VG 2FH2A 1V6FA 2W0IA 3DAWB 3TU5B 5KYYA 3FFKA 1WM4A 3CJBG 1CFYA 5KYYB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3FG6 A;  4S10 C;  1T44 G;  4Z94 G;  2LLF A;  1J72 A;  1NLV G;  1P8X A;  2FGH A;  3FG7 A;  5KYW A;  1VKK A;  1ESV S;  2D8B A;  3EGX A;  4PKG G;  5KYW B;  1SVQ A;  1PD0 A;  1D0N A;  1C0F S;  3EGX B;  1Q8G A;  2FH1 A;  2MOT A;  1YVN G;  3CJC G;  4BEX 1;  3EH2 A;  4PKI G;  5L6W C;  5FAE A;  1T3X A;  1C0G S;  3EH1 A;  2HD7 A;  3CI5 G;  4CBU G;  2FH3 A;  1DEJ S;  1PCX A;  2MV2 A;  5A1M A;  1X67 A;  1EQY S;  1KCQ A;  1QPV A;  1JHW A;  1NPH A;  3A5M S;  2LXX A;  1M2O A;  1TMW A;  5KYN A;  1YAG G;  3EG9 B;  1F7S A;  5HVK D;  1SVY A;  1NMD G;  1NM1 G;  1WFS A;  3FFN A;  4JD2 H;  4CBX G;  2FF6 G;  3A5N S;  4PKH B;  2L72 A;  1SVR A;  1M2V A;  2QTV A;  1AK7 A;  3EGD B;  1COF A;  1M2V B;  3A5L S;  3Q2B A;  4KED A;  4KEE A;  1RGI G;  1P8Z G;  1UDM A;  1HQZ 1;  3EG9 A;  3EFO A;  5KYX B;  1D4X G;  1VFQ A;  3EFO B;  1M4J A;  1AK6 A;  2FF3 A;  1WNJ A;  1CNU A;  2NUT A;  2VIL A;  3L50 A;  2NUT B;  2VAC A;  1Q8X A;  1AHQ A;  4LIZ A;  1T3Y A;  2NUP A;  5DD2 A;  2LJ8 A;  3EGD A;  2MP4 A;  2XFA A;  3A5O S;  5KYU A;  2NUP B;  2KVK A;  3CIP G;  2XF1 A;  5FAF A;  2VIK A;  5IVU A;  2I2Q A;  4CBW G;  1MDU A;  5KYU B;  4KEF A;  1TVJ A;  1T2L A;  1PD1 A;  5KYX A;  5HVK B;  2FH4 A;  1H1V G;  2FH2 A;  1V6F A;  2W0I A;  3DAW B;  3TU5 B;  5KYY A;  3FFK A;  1WM4 A;  3CJB G;  1CFY A;  5KYY B; 
#chains in the Genus database with same CATH topology
 3FG6 A;  4S10 C;  1T44 G;  4Z94 G;  2LLF A;  1J72 A;  1NLV G;  1P8X A;  2FGH A;  3FG7 A;  5KYW A;  1VKK A;  1ESV S;  2D8B A;  3EGX A;  4PKG G;  5KYW B;  1SVQ A;  1PD0 A;  1D0N A;  1C0F S;  3EGX B;  1Q8G A;  2FH1 A;  2MOT A;  1YVN G;  3CJC G;  4BEX 1;  3EH2 A;  4PKI G;  5L6W C;  5FAE A;  1T3X A;  3DA7 A;  1C0G S;  3EH1 A;  2HD7 A;  3CI5 G;  4CBU G;  2FH3 A;  1DEJ S;  1PCX A;  2MV2 A;  5A1M A;  1X67 A;  1EQY S;  1KCQ A;  1QPV A;  1JHW A;  1NPH A;  3A5M S;  2LXX A;  1M2O A;  1TMW A;  5KYN A;  1YAG G;  3EG9 B;  1F7S A;  5HVK D;  1SVY A;  1NMD G;  1NM1 G;  1WFS A;  3FFN A;  4JD2 H;  4CBX G;  2FF6 G;  3A5N S;  4PKH B;  2L72 A;  1SVR A;  1M2V A;  2QTV A;  1AK7 A;  3EGD B;  1COF A;  1M2V B;  3A5L S;  3Q2B A;  4KED A;  4KEE A;  1RGI G;  1P8Z G;  1UDM A;  1HQZ 1;  3EG9 A;  3EFO A;  5KYX B;  1D4X G;  1VFQ A;  3EFO B;  1M4J A;  1AK6 A;  2FF3 A;  1WNJ A;  1CNU A;  2NUT A;  2VIL A;  3L50 A;  2NUT B;  2VAC A;  1Q8X A;  1AHQ A;  4LIZ A;  1T3Y A;  2NUP A;  5DD2 A;  2LJ8 A;  3EGD A;  2MP4 A;  2XFA A;  3A5O S;  5KYU A;  2NUP B;  2KVK A;  3CIP G;  2XF1 A;  5FAF A;  2VIK A;  5IVU A;  2I2Q A;  4CBW G;  1MDU A;  5KYU B;  4KEF A;  1TVJ A;  1T2L A;  1PD1 A;  5KYX A;  5HVK B;  2FH4 A;  1H1V G;  2FH2 A;  1V6F A;  2W0I A;  3DAW B;  3TU5 B;  5KYY A;  3FFK A;  1WM4 A;  3CJB G;  1CFY A;  5KYY B; 
#chains in the Genus database with same CATH homology
 3FG6 A;  4S10 C;  1T44 G;  4Z94 G;  2LLF A;  1J72 A;  1NLV G;  1P8X A;  2FGH A;  3FG7 A;  5KYW A;  1VKK A;  1ESV S;  2D8B A;  3EGX A;  4PKG G;  5KYW B;  1SVQ A;  1PD0 A;  1D0N A;  1C0F S;  3EGX B;  1Q8G A;  2FH1 A;  2MOT A;  1YVN G;  3CJC G;  4BEX 1;  3EH2 A;  4PKI G;  5L6W C;  5FAE A;  1T3X A;  3DA7 A;  1C0G S;  3EH1 A;  2HD7 A;  3CI5 G;  4CBU G;  2FH3 A;  1DEJ S;  1PCX A;  2MV2 A;  5A1M A;  1X67 A;  1EQY S;  1KCQ A;  1QPV A;  1JHW A;  1NPH A;  3A5M S;  2LXX A;  1M2O A;  1TMW A;  5KYN A;  1YAG G;  3EG9 B;  1F7S A;  5HVK D;  1SVY A;  1NMD G;  1NM1 G;  1WFS A;  3FFN A;  4JD2 H;  4CBX G;  2FF6 G;  3A5N S;  4PKH B;  2L72 A;  1SVR A;  1M2V A;  2QTV A;  1AK7 A;  3EGD B;  1COF A;  1M2V B;  3A5L S;  3Q2B A;  4KED A;  4KEE A;  1RGI G;  1P8Z G;  1UDM A;  1HQZ 1;  3EG9 A;  3EFO A;  5KYX B;  1D4X G;  1VFQ A;  3EFO B;  1M4J A;  1AK6 A;  2FF3 A;  1WNJ A;  1CNU A;  2NUT A;  2VIL A;  3L50 A;  2NUT B;  2VAC A;  1Q8X A;  1AHQ A;  4LIZ A;  1T3Y A;  2NUP A;  5DD2 A;  2LJ8 A;  3EGD A;  2MP4 A;  2XFA A;  3A5O S;  5KYU A;  2NUP B;  2KVK A;  3CIP G;  2XF1 A;  5FAF A;  2VIK A;  5IVU A;  2I2Q A;  4CBW G;  1MDU A;  5KYU B;  4KEF A;  1TVJ A;  1T2L A;  1PD1 A;  5KYX A;  5HVK B;  2FH4 A;  1H1V G;  2FH2 A;  1V6F A;  2W0I A;  3DAW B;  3TU5 B;  5KYY A;  3FFK A;  1WM4 A;  3CJB G;  1CFY A;  5KYY B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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