2LJ8A

Solution structure of adf/cofilin from trypanosoma brucei
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
136
structure length
136
Chain Sequence
MAMSGVSVADECVTALNDLRHKKSRYVIMHIVDQKSIAVKTIGERGANFDQFIEAIDKNVPCYAAFDFEYTTNDGPRDKLILISWNPDSGAPRTKMLYSSSRDALVPLTQGFQGIQANDASGLDFEEISRKVKSNR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title 1H and 15N Assigned Chemical Shifts for ADF/Cofilin from Trypanosoma brucei
rcsb
molecule tags Protein binding
source organism Trypanosoma brucei
molecule keywords Cofilin/actin depolymerizing factor, putative
total genus 25
structure length 136
sequence length 136
ec nomenclature
pdb deposition date 2011-09-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00241 Cofilin_ADF Cofilin/tropomyosin-type actin-binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 2lj8A00
2VIKA 4PKHB 5KYXB 2FH4A 2FF3A 5FAEA 1Q8XA 2XFAA 1COFA 2FH2A 1WNJA 3EGDB 1PD0A 2NUTA 5KYUB 1M2OA 3CJCG 1D4XG 3EH2A 3EGXA 2LLFA 4KEFA 1YAGG 5HVKB 1RGIG 3FG7A 1T3YA 2MP4A 3L50A 3Q2BA 5FAFA 4CBWG 1M4JA 5L6WC 1JHWA 2FF6G 1PD1A 1C0GS 1P8ZG 5IVUA 1VKKA 1J72A 2L72A 3EFOB 2FH1A 1T44G 2VACA 3CJBG 3FG6A 5KYWB 1DEJS 3FFNA 4S10C 5KYYB 1H1VG 4JD2H 4CBUG 4CBXG 1SVQA 2W0IA 4KEEA 1YVNG 2LXXA 1X67A 2FH3A 3TU5B 1VFQA 3A5MS 2VILA 1UDMA 1AK6A 3EG9B 2MV2A 2XF1A 1Q8GA 2D8BA 5KYXA 1NPHA 4PKIG 1AK7A 4LIZA 1V6FA 1PCXA 5KYWA 4PKGG 3CI5G 1M2VB 2LJ8A 3A5LS 3EGDA 1CFYA 2MOTA 5KYUA 3FFKA 3A5OS 1CNUA 1F7SA 2NUPB 1TVJA 2QTVA 1ESVS 2KVKA 1KCQA 1SVYA 1WFSA 1TMWA 1NLVG 1NMDG 1D0NA 3EFOA 4BEX1 2HD7A 2I2QA 1EQYS 1M2VA 5HVKD 5KYYA 1C0FS 1P8XA 4Z94G 3EH1A 1HQZ1 1SVRA 1NM1G 2FGHA 2NUTB 5A1MA 1WM4A 2NUPA 1MDUA 3CIPG 1T3XA 3EGXB 3A5NS 1T2LA 1QPVA 4KEDA 3DAWB 1AHQA 5DD2A 5KYNA 3EG9A
chains in the Genus database with same CATH superfamily
2VIKA 4PKHB 5KYXB 2FH4A 2FF3A 5FAEA 1Q8XA 2XFAA 1COFA 2FH2A 1WNJA 3EGDB 1PD0A 2NUTA 5KYUB 1M2OA 3CJCG 1D4XG 3EH2A 3EGXA 2LLFA 4KEFA 1YAGG 5HVKB 1RGIG 3FG7A 1T3YA 2MP4A 3L50A 3Q2BA 5FAFA 4CBWG 1M4JA 5L6WC 1JHWA 2FF6G 1PD1A 1C0GS 1P8ZG 5IVUA 1VKKA 1J72A 2L72A 3EFOB 2FH1A 1T44G 2VACA 3CJBG 3FG6A 5KYWB 1DEJS 3FFNA 4S10C 5KYYB 1H1VG 4JD2H 4CBUG 4CBXG 1SVQA 2W0IA 4KEEA 1YVNG 2LXXA 1X67A 2FH3A 3TU5B 1VFQA 3A5MS 2VILA 1UDMA 1AK6A 3EG9B 2MV2A 2XF1A 1Q8GA 2D8BA 5KYXA 1NPHA 4PKIG 1AK7A 4LIZA 1V6FA 1PCXA 5KYWA 4PKGG 3CI5G 1M2VB 2LJ8A 3A5LS 3EGDA 1CFYA 2MOTA 5KYUA 3FFKA 3A5OS 1CNUA 1F7SA 2NUPB 1TVJA 2QTVA 1ESVS 2KVKA 3DA7A 1KCQA 1SVYA 1WFSA 1TMWA 1NLVG 1NMDG 1D0NA 3EFOA 4BEX1 2HD7A 2I2QA 1EQYS 1M2VA 5HVKD 5KYYA 1C0FS 1P8XA 4Z94G 3EH1A 1HQZ1 1SVRA 1NM1G 2FGHA 2NUTB 5A1MA 1WM4A 2NUPA 1MDUA 3CIPG 1T3XA 3EGXB 3A5NS 1T2LA 1QPVA 4KEDA 3DAWB 1AHQA 5DD2A 5KYNA 3EG9A
chains in the Genus database with same CATH topology
2VIKA 4PKHB 5KYXB 2FH4A 2FF3A 5FAEA 1Q8XA 2XFAA 1COFA 2FH2A 1WNJA 3EGDB 1PD0A 2NUTA 5KYUB 1M2OA 3CJCG 1D4XG 3EH2A 3EGXA 2LLFA 4KEFA 1YAGG 5HVKB 1RGIG 3FG7A 1T3YA 2MP4A 3L50A 3Q2BA 5FAFA 4CBWG 1M4JA 5L6WC 1JHWA 2FF6G 1PD1A 1C0GS 1P8ZG 5IVUA 1VKKA 1J72A 2L72A 3EFOB 2FH1A 1T44G 2VACA 3CJBG 3FG6A 5KYWB 1DEJS 3FFNA 4S10C 5KYYB 1H1VG 4JD2H 4CBUG 4CBXG 1SVQA 2W0IA 4KEEA 1YVNG 2LXXA 1X67A 2FH3A 3TU5B 1VFQA 3A5MS 2VILA 1UDMA 1AK6A 3EG9B 2MV2A 2XF1A 1Q8GA 2D8BA 5KYXA 1NPHA 4PKIG 1AK7A 4LIZA 1V6FA 1PCXA 5KYWA 4PKGG 3CI5G 1M2VB 2LJ8A 3A5LS 3EGDA 1CFYA 2MOTA 5KYUA 3FFKA 3A5OS 1CNUA 1F7SA 2NUPB 1TVJA 2QTVA 1ESVS 2KVKA 3DA7A 1KCQA 1SVYA 1WFSA 1TMWA 1NLVG 1NMDG 1D0NA 3EFOA 4BEX1 2HD7A 2I2QA 1EQYS 1M2VA 5HVKD 5KYYA 1C0FS 1P8XA 4Z94G 3EH1A 1HQZ1 1SVRA 1NM1G 2FGHA 2NUTB 5A1MA 1WM4A 2NUPA 1MDUA 3CIPG 1T3XA 3EGXB 3A5NS 1T2LA 1QPVA 4KEDA 3DAWB 1AHQA 5DD2A 5KYNA 3EG9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2VIK A;  4PKH B;  5KYX B;  2FH4 A;  2FF3 A;  5FAE A;  1Q8X A;  2XFA A;  1COF A;  2FH2 A;  1WNJ A;  3EGD B;  1PD0 A;  2NUT A;  5KYU B;  1M2O A;  3CJC G;  1D4X G;  3EH2 A;  3EGX A;  2LLF A;  4KEF A;  1YAG G;  5HVK B;  1RGI G;  3FG7 A;  1T3Y A;  2MP4 A;  3L50 A;  3Q2B A;  5FAF A;  4CBW G;  1M4J A;  5L6W C;  1JHW A;  2FF6 G;  1PD1 A;  1C0G S;  1P8Z G;  5IVU A;  1VKK A;  1J72 A;  2L72 A;  3EFO B;  2FH1 A;  1T44 G;  2VAC A;  3CJB G;  3FG6 A;  5KYW B;  1DEJ S;  3FFN A;  4S10 C;  5KYY B;  1H1V G;  4JD2 H;  4CBU G;  4CBX G;  1SVQ A;  2W0I A;  4KEE A;  1YVN G;  2LXX A;  1X67 A;  2FH3 A;  3TU5 B;  1VFQ A;  3A5M S;  2VIL A;  1UDM A;  1AK6 A;  3EG9 B;  2MV2 A;  2XF1 A;  1Q8G A;  2D8B A;  5KYX A;  1NPH A;  4PKI G;  1AK7 A;  4LIZ A;  1V6F A;  1PCX A;  5KYW A;  4PKG G;  3CI5 G;  1M2V B;  2LJ8 A;  3A5L S;  3EGD A;  1CFY A;  2MOT A;  5KYU A;  3FFK A;  3A5O S;  1CNU A;  1F7S A;  2NUP B;  1TVJ A;  2QTV A;  1ESV S;  2KVK A;  1KCQ A;  1SVY A;  1WFS A;  1TMW A;  1NLV G;  1NMD G;  1D0N A;  3EFO A;  4BEX 1;  2HD7 A;  2I2Q A;  1EQY S;  1M2V A;  5HVK D;  5KYY A;  1C0F S;  1P8X A;  4Z94 G;  3EH1 A;  1HQZ 1;  1SVR A;  1NM1 G;  2FGH A;  2NUT B;  5A1M A;  1WM4 A;  2NUP A;  1MDU A;  3CIP G;  1T3X A;  3EGX B;  3A5N S;  1T2L A;  1QPV A;  4KED A;  3DAW B;  1AHQ A;  5DD2 A;  5KYN A;  3EG9 A; 
#chains in the Genus database with same CATH topology
 2VIK A;  4PKH B;  5KYX B;  2FH4 A;  2FF3 A;  5FAE A;  1Q8X A;  2XFA A;  1COF A;  2FH2 A;  1WNJ A;  3EGD B;  1PD0 A;  2NUT A;  5KYU B;  1M2O A;  3CJC G;  1D4X G;  3EH2 A;  3EGX A;  2LLF A;  4KEF A;  1YAG G;  5HVK B;  1RGI G;  3FG7 A;  1T3Y A;  2MP4 A;  3L50 A;  3Q2B A;  5FAF A;  4CBW G;  1M4J A;  5L6W C;  1JHW A;  2FF6 G;  1PD1 A;  1C0G S;  1P8Z G;  5IVU A;  1VKK A;  1J72 A;  2L72 A;  3EFO B;  2FH1 A;  1T44 G;  2VAC A;  3CJB G;  3FG6 A;  5KYW B;  1DEJ S;  3FFN A;  4S10 C;  5KYY B;  1H1V G;  4JD2 H;  4CBU G;  4CBX G;  1SVQ A;  2W0I A;  4KEE A;  1YVN G;  2LXX A;  1X67 A;  2FH3 A;  3TU5 B;  1VFQ A;  3A5M S;  2VIL A;  1UDM A;  1AK6 A;  3EG9 B;  2MV2 A;  2XF1 A;  1Q8G A;  2D8B A;  5KYX A;  1NPH A;  4PKI G;  1AK7 A;  4LIZ A;  1V6F A;  1PCX A;  5KYW A;  4PKG G;  3CI5 G;  1M2V B;  2LJ8 A;  3A5L S;  3EGD A;  1CFY A;  2MOT A;  5KYU A;  3FFK A;  3A5O S;  1CNU A;  1F7S A;  2NUP B;  1TVJ A;  2QTV A;  1ESV S;  2KVK A;  3DA7 A;  1KCQ A;  1SVY A;  1WFS A;  1TMW A;  1NLV G;  1NMD G;  1D0N A;  3EFO A;  4BEX 1;  2HD7 A;  2I2Q A;  1EQY S;  1M2V A;  5HVK D;  5KYY A;  1C0F S;  1P8X A;  4Z94 G;  3EH1 A;  1HQZ 1;  1SVR A;  1NM1 G;  2FGH A;  2NUT B;  5A1M A;  1WM4 A;  2NUP A;  1MDU A;  3CIP G;  1T3X A;  3EGX B;  3A5N S;  1T2L A;  1QPV A;  4KED A;  3DAW B;  1AHQ A;  5DD2 A;  5KYN A;  3EG9 A; 
#chains in the Genus database with same CATH homology
 2VIK A;  4PKH B;  5KYX B;  2FH4 A;  2FF3 A;  5FAE A;  1Q8X A;  2XFA A;  1COF A;  2FH2 A;  1WNJ A;  3EGD B;  1PD0 A;  2NUT A;  5KYU B;  1M2O A;  3CJC G;  1D4X G;  3EH2 A;  3EGX A;  2LLF A;  4KEF A;  1YAG G;  5HVK B;  1RGI G;  3FG7 A;  1T3Y A;  2MP4 A;  3L50 A;  3Q2B A;  5FAF A;  4CBW G;  1M4J A;  5L6W C;  1JHW A;  2FF6 G;  1PD1 A;  1C0G S;  1P8Z G;  5IVU A;  1VKK A;  1J72 A;  2L72 A;  3EFO B;  2FH1 A;  1T44 G;  2VAC A;  3CJB G;  3FG6 A;  5KYW B;  1DEJ S;  3FFN A;  4S10 C;  5KYY B;  1H1V G;  4JD2 H;  4CBU G;  4CBX G;  1SVQ A;  2W0I A;  4KEE A;  1YVN G;  2LXX A;  1X67 A;  2FH3 A;  3TU5 B;  1VFQ A;  3A5M S;  2VIL A;  1UDM A;  1AK6 A;  3EG9 B;  2MV2 A;  2XF1 A;  1Q8G A;  2D8B A;  5KYX A;  1NPH A;  4PKI G;  1AK7 A;  4LIZ A;  1V6F A;  1PCX A;  5KYW A;  4PKG G;  3CI5 G;  1M2V B;  2LJ8 A;  3A5L S;  3EGD A;  1CFY A;  2MOT A;  5KYU A;  3FFK A;  3A5O S;  1CNU A;  1F7S A;  2NUP B;  1TVJ A;  2QTV A;  1ESV S;  2KVK A;  3DA7 A;  1KCQ A;  1SVY A;  1WFS A;  1TMW A;  1NLV G;  1NMD G;  1D0N A;  3EFO A;  4BEX 1;  2HD7 A;  2I2Q A;  1EQY S;  1M2V A;  5HVK D;  5KYY A;  1C0F S;  1P8X A;  4Z94 G;  3EH1 A;  1HQZ 1;  1SVR A;  1NM1 G;  2FGH A;  2NUT B;  5A1M A;  1WM4 A;  2NUP A;  1MDU A;  3CIP G;  1T3X A;  3EGX B;  3A5N S;  1T2L A;  1QPV A;  4KED A;  3DAW B;  1AHQ A;  5DD2 A;  5KYN A;  3EG9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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