4KEDA

Crystal structure of cofilin mutant (cof1-157p)
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
134
structure length
131
Chain Sequence
VAVADESLTAFNDLKLGKKYKFILFGLNDAKTEIVVKETSTDPSYDAFLEKLPENDCLYAIYDFEYEINGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSTDVQGTDFSEVSYDSVLEDVSRG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of Cofilin Mutant (cof1-157p)
rcsb
molecule tags Actin binding protein
source organism Saccharomyces cerevisiae
molecule keywords Cofilin
total genus 35
structure length 131
sequence length 134
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-04-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00241 Cofilin_ADF Cofilin/tropomyosin-type actin-binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 4kedA00
5KYYA 2I2QA 5KYNA 2FH3A 3FFNA 4PKHB 4CBUG 2FH1A 3EG9B 1X67A 1PCXA 1TMWA 5HVKD 2MOTA 1Q8XA 3TU5B 2FF6G 2NUPA 5KYWB 2L72A 1DEJS 3FG7A 1M2VA 1AK7A 1AHQA 1P8XA 2MV2A 4Z94G 2FF3A 5FAFA 1Q8GA 4PKGG 3EGDA 4CBWG 1PD0A 2LXXA 3CI5G 1SVQA 1CNUA 2FGHA 1WM4A 1RGIG 4KEEA 1T44G 5IVUA 3EFOA 2W0IA 2D8BA 1H1VG 2FH4A 1YVNG 5KYUB 5KYXB 1TVJA 5A1MA 1F7SA 2LJ8A 3EG9A 4CBXG 2LLFA 3A5MS 1COFA 5KYWA 5HVKB 2QTVA 3DAWB 1AK6A 1NMDG 2VIKA 1QPVA 2XF1A 3FFKA 1C0FS 3CJCG 1EQYS 2NUTB 2HD7A 2KVKA 4KEDA 3EH2A 1PD1A 4S10C 5FAEA 2VILA 1MDUA 4JD2H 3EGXB 1D0NA 4BEX1 1WFSA 5L6WC 1VKKA 1JHWA 4PKIG 1WNJA 5KYYB 1NLVG 1SVRA 4KEFA 5KYUA 3FG6A 5KYXA 3A5LS 2XFAA 1T2LA 1V6FA 3Q2BA 2NUPB 1T3XA 3A5OS 5DD2A 3CIPG 2MP4A 1M2VB 1M2OA 1NM1G 1KCQA 4LIZA 1M4JA 1J72A 3EGDB 1D4XG 1CFYA 1P8ZG 1T3YA 2NUTA 1ESVS 1YAGG 3A5NS 1C0GS 3CJBG 3L50A 3EH1A 1HQZ1 3EGXA 1SVYA 1NPHA 2FH2A 1VFQA 2VACA 1UDMA 3EFOB
chains in the Genus database with same CATH superfamily
5KYYA 2I2QA 5KYNA 2FH3A 3FFNA 4PKHB 4CBUG 2FH1A 3EG9B 1X67A 1PCXA 1TMWA 5HVKD 2MOTA 1Q8XA 3TU5B 2FF6G 2NUPA 5KYWB 2L72A 1DEJS 3FG7A 1M2VA 1AK7A 1AHQA 1P8XA 2MV2A 4Z94G 2FF3A 5FAFA 1Q8GA 4PKGG 3EGDA 4CBWG 1PD0A 2LXXA 3CI5G 1SVQA 1CNUA 2FGHA 1WM4A 1RGIG 4KEEA 1T44G 5IVUA 3EFOA 2W0IA 2D8BA 1H1VG 2FH4A 1YVNG 5KYUB 5KYXB 1TVJA 5A1MA 1F7SA 2LJ8A 3EG9A 4CBXG 2LLFA 3A5MS 1COFA 5KYWA 5HVKB 2QTVA 3DAWB 1AK6A 1NMDG 2VIKA 1QPVA 2XF1A 3FFKA 1C0FS 3CJCG 1EQYS 2NUTB 2HD7A 2KVKA 4KEDA 3EH2A 1PD1A 4S10C 5FAEA 2VILA 1MDUA 4JD2H 3EGXB 1D0NA 4BEX1 1WFSA 5L6WC 1VKKA 1JHWA 4PKIG 1WNJA 5KYYB 1NLVG 3DA7A 1SVRA 4KEFA 5KYUA 3FG6A 5KYXA 3A5LS 2XFAA 1T2LA 1V6FA 3Q2BA 2NUPB 1T3XA 3A5OS 5DD2A 3CIPG 2MP4A 1M2VB 1M2OA 1NM1G 1KCQA 4LIZA 1M4JA 1J72A 3EGDB 1D4XG 1CFYA 1P8ZG 1T3YA 2NUTA 1ESVS 1YAGG 3A5NS 1C0GS 3CJBG 3L50A 3EH1A 1HQZ1 3EGXA 1SVYA 1NPHA 2FH2A 1VFQA 2VACA 1UDMA 3EFOB
chains in the Genus database with same CATH topology
5KYYA 2I2QA 5KYNA 2FH3A 3FFNA 4PKHB 4CBUG 2FH1A 3EG9B 1X67A 1PCXA 1TMWA 5HVKD 2MOTA 1Q8XA 3TU5B 2FF6G 2NUPA 5KYWB 2L72A 1DEJS 3FG7A 1M2VA 1AK7A 1AHQA 1P8XA 2MV2A 4Z94G 2FF3A 5FAFA 1Q8GA 4PKGG 3EGDA 4CBWG 1PD0A 2LXXA 3CI5G 1SVQA 1CNUA 2FGHA 1WM4A 1RGIG 4KEEA 1T44G 5IVUA 3EFOA 2W0IA 2D8BA 1H1VG 2FH4A 1YVNG 5KYUB 5KYXB 1TVJA 5A1MA 1F7SA 2LJ8A 3EG9A 4CBXG 2LLFA 3A5MS 1COFA 5KYWA 5HVKB 2QTVA 3DAWB 1AK6A 1NMDG 2VIKA 1QPVA 2XF1A 3FFKA 1C0FS 3CJCG 1EQYS 2NUTB 2HD7A 2KVKA 4KEDA 3EH2A 1PD1A 4S10C 5FAEA 2VILA 1MDUA 4JD2H 3EGXB 1D0NA 4BEX1 1WFSA 5L6WC 1VKKA 1JHWA 4PKIG 1WNJA 5KYYB 1NLVG 3DA7A 1SVRA 4KEFA 5KYUA 3FG6A 5KYXA 3A5LS 2XFAA 1T2LA 1V6FA 3Q2BA 2NUPB 1T3XA 3A5OS 5DD2A 3CIPG 2MP4A 1M2VB 1M2OA 1NM1G 1KCQA 4LIZA 1M4JA 1J72A 3EGDB 1D4XG 1CFYA 1P8ZG 1T3YA 2NUTA 1ESVS 1YAGG 3A5NS 1C0GS 3CJBG 3L50A 3EH1A 1HQZ1 3EGXA 1SVYA 1NPHA 2FH2A 1VFQA 2VACA 1UDMA 3EFOB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5KYY A;  2I2Q A;  5KYN A;  2FH3 A;  3FFN A;  4PKH B;  4CBU G;  2FH1 A;  3EG9 B;  1X67 A;  1PCX A;  1TMW A;  5HVK D;  2MOT A;  1Q8X A;  3TU5 B;  2FF6 G;  2NUP A;  5KYW B;  2L72 A;  1DEJ S;  3FG7 A;  1M2V A;  1AK7 A;  1AHQ A;  1P8X A;  2MV2 A;  4Z94 G;  2FF3 A;  5FAF A;  1Q8G A;  4PKG G;  3EGD A;  4CBW G;  1PD0 A;  2LXX A;  3CI5 G;  1SVQ A;  1CNU A;  2FGH A;  1WM4 A;  1RGI G;  4KEE A;  1T44 G;  5IVU A;  3EFO A;  2W0I A;  2D8B A;  1H1V G;  2FH4 A;  1YVN G;  5KYU B;  5KYX B;  1TVJ A;  5A1M A;  1F7S A;  2LJ8 A;  3EG9 A;  4CBX G;  2LLF A;  3A5M S;  1COF A;  5KYW A;  5HVK B;  2QTV A;  3DAW B;  1AK6 A;  1NMD G;  2VIK A;  1QPV A;  2XF1 A;  3FFK A;  1C0F S;  3CJC G;  1EQY S;  2NUT B;  2HD7 A;  2KVK A;  4KED A;  3EH2 A;  1PD1 A;  4S10 C;  5FAE A;  2VIL A;  1MDU A;  4JD2 H;  3EGX B;  1D0N A;  4BEX 1;  1WFS A;  5L6W C;  1VKK A;  1JHW A;  4PKI G;  1WNJ A;  5KYY B;  1NLV G;  1SVR A;  4KEF A;  5KYU A;  3FG6 A;  5KYX A;  3A5L S;  2XFA A;  1T2L A;  1V6F A;  3Q2B A;  2NUP B;  1T3X A;  3A5O S;  5DD2 A;  3CIP G;  2MP4 A;  1M2V B;  1M2O A;  1NM1 G;  1KCQ A;  4LIZ A;  1M4J A;  1J72 A;  3EGD B;  1D4X G;  1CFY A;  1P8Z G;  1T3Y A;  2NUT A;  1ESV S;  1YAG G;  3A5N S;  1C0G S;  3CJB G;  3L50 A;  3EH1 A;  1HQZ 1;  3EGX A;  1SVY A;  1NPH A;  2FH2 A;  1VFQ A;  2VAC A;  1UDM A;  3EFO B; 
#chains in the Genus database with same CATH topology
 5KYY A;  2I2Q A;  5KYN A;  2FH3 A;  3FFN A;  4PKH B;  4CBU G;  2FH1 A;  3EG9 B;  1X67 A;  1PCX A;  1TMW A;  5HVK D;  2MOT A;  1Q8X A;  3TU5 B;  2FF6 G;  2NUP A;  5KYW B;  2L72 A;  1DEJ S;  3FG7 A;  1M2V A;  1AK7 A;  1AHQ A;  1P8X A;  2MV2 A;  4Z94 G;  2FF3 A;  5FAF A;  1Q8G A;  4PKG G;  3EGD A;  4CBW G;  1PD0 A;  2LXX A;  3CI5 G;  1SVQ A;  1CNU A;  2FGH A;  1WM4 A;  1RGI G;  4KEE A;  1T44 G;  5IVU A;  3EFO A;  2W0I A;  2D8B A;  1H1V G;  2FH4 A;  1YVN G;  5KYU B;  5KYX B;  1TVJ A;  5A1M A;  1F7S A;  2LJ8 A;  3EG9 A;  4CBX G;  2LLF A;  3A5M S;  1COF A;  5KYW A;  5HVK B;  2QTV A;  3DAW B;  1AK6 A;  1NMD G;  2VIK A;  1QPV A;  2XF1 A;  3FFK A;  1C0F S;  3CJC G;  1EQY S;  2NUT B;  2HD7 A;  2KVK A;  4KED A;  3EH2 A;  1PD1 A;  4S10 C;  5FAE A;  2VIL A;  1MDU A;  4JD2 H;  3EGX B;  1D0N A;  4BEX 1;  1WFS A;  5L6W C;  1VKK A;  1JHW A;  4PKI G;  1WNJ A;  5KYY B;  1NLV G;  3DA7 A;  1SVR A;  4KEF A;  5KYU A;  3FG6 A;  5KYX A;  3A5L S;  2XFA A;  1T2L A;  1V6F A;  3Q2B A;  2NUP B;  1T3X A;  3A5O S;  5DD2 A;  3CIP G;  2MP4 A;  1M2V B;  1M2O A;  1NM1 G;  1KCQ A;  4LIZ A;  1M4J A;  1J72 A;  3EGD B;  1D4X G;  1CFY A;  1P8Z G;  1T3Y A;  2NUT A;  1ESV S;  1YAG G;  3A5N S;  1C0G S;  3CJB G;  3L50 A;  3EH1 A;  1HQZ 1;  3EGX A;  1SVY A;  1NPH A;  2FH2 A;  1VFQ A;  2VAC A;  1UDM A;  3EFO B; 
#chains in the Genus database with same CATH homology
 5KYY A;  2I2Q A;  5KYN A;  2FH3 A;  3FFN A;  4PKH B;  4CBU G;  2FH1 A;  3EG9 B;  1X67 A;  1PCX A;  1TMW A;  5HVK D;  2MOT A;  1Q8X A;  3TU5 B;  2FF6 G;  2NUP A;  5KYW B;  2L72 A;  1DEJ S;  3FG7 A;  1M2V A;  1AK7 A;  1AHQ A;  1P8X A;  2MV2 A;  4Z94 G;  2FF3 A;  5FAF A;  1Q8G A;  4PKG G;  3EGD A;  4CBW G;  1PD0 A;  2LXX A;  3CI5 G;  1SVQ A;  1CNU A;  2FGH A;  1WM4 A;  1RGI G;  4KEE A;  1T44 G;  5IVU A;  3EFO A;  2W0I A;  2D8B A;  1H1V G;  2FH4 A;  1YVN G;  5KYU B;  5KYX B;  1TVJ A;  5A1M A;  1F7S A;  2LJ8 A;  3EG9 A;  4CBX G;  2LLF A;  3A5M S;  1COF A;  5KYW A;  5HVK B;  2QTV A;  3DAW B;  1AK6 A;  1NMD G;  2VIK A;  1QPV A;  2XF1 A;  3FFK A;  1C0F S;  3CJC G;  1EQY S;  2NUT B;  2HD7 A;  2KVK A;  4KED A;  3EH2 A;  1PD1 A;  4S10 C;  5FAE A;  2VIL A;  1MDU A;  4JD2 H;  3EGX B;  1D0N A;  4BEX 1;  1WFS A;  5L6W C;  1VKK A;  1JHW A;  4PKI G;  1WNJ A;  5KYY B;  1NLV G;  3DA7 A;  1SVR A;  4KEF A;  5KYU A;  3FG6 A;  5KYX A;  3A5L S;  2XFA A;  1T2L A;  1V6F A;  3Q2B A;  2NUP B;  1T3X A;  3A5O S;  5DD2 A;  3CIP G;  2MP4 A;  1M2V B;  1M2O A;  1NM1 G;  1KCQ A;  4LIZ A;  1M4J A;  1J72 A;  3EGD B;  1D4X G;  1CFY A;  1P8Z G;  1T3Y A;  2NUT A;  1ESV S;  1YAG G;  3A5N S;  1C0G S;  3CJB G;  3L50 A;  3EH1 A;  1HQZ 1;  3EGX A;  1SVY A;  1NPH A;  2FH2 A;  1VFQ A;  2VAC A;  1UDM A;  3EFO B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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