1TVJA

Solution structure of chick cofilin
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
166
structure length
166
Chain Sequence
MASGVTVNDEVIKVFNDMKVRKSSTPEEIKKRKKAVLFCLSDDKKQIIVEEAKQILVGDIGDTVEDPYTAFVKLLPLNDCRYALYDATYETKESKKEDLVFIFWAPESAPLKSKMIYASSKDAIKKKFTGIKHEWQVNGLDDIKDRSTLGEKLGGNVVVSLEGKPL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title NMR Study of the Molecular Basis for Phosphoinositide Regulation of the Cofilin-Actin Interactions.
rcsb
molecule tags Actin-binding protein
source organism Gallus gallus
molecule keywords Cofilin
total genus 35
structure length 166
sequence length 166
ec nomenclature
pdb deposition date 2004-06-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00241 Cofilin_ADF Cofilin/tropomyosin-type actin-binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 1tvjA00
1T44G 2NUPB 1C0FS 1P8XA 1PD1A 1C0GS 4BEX1 1SVRA 2FF3A 3FG7A 1J72A 1NM1G 2LJ8A 1AK6A 3EFOA 3CJBG 2XFAA 5FAFA 4KEDA 2L72A 2FH3A 2FH1A 5FAEA 3EGDA 3A5NS 4PKGG 1T3YA 4KEFA 5KYYB 3CIPG 2W0IA 1PCXA 1PD0A 1M2VB 4PKIG 1YAGG 1RGIG 4LIZA 1AHQA 3A5MS 5HVKD 5DD2A 1VKKA 2NUPA 5KYUB 4CBWG 2HD7A 5IVUA 1COFA 1ESVS 3L50A 3FFKA 2LXXA 2KVKA 1CFYA 5L6WC 1EQYS 1T2LA 1WM4A 5KYNA 1MDUA 4JD2H 5KYYA 2LLFA 3TU5B 1M2VA 4CBUG 1DEJS 5KYXB 4S10C 2MV2A 3Q2BA 1SVYA 1Q8GA 5KYUA 3DAWB 1M4JA 1P8ZG 2I2QA 2QTVA 1NMDG 3CJCG 1V6FA 3EH1A 3EGXB 1YVNG 3EGXA 2MOTA 2FH4A 1UDMA 4Z94G 5HVKB 1WFSA 1KCQA 1D4XG 1X67A 1WNJA 3EH2A 5A1MA 1HQZ1 2VILA 5KYXA 1M2OA 2VACA 2FF6G 2MP4A 4KEEA 3EFOB 1H1VG 1TVJA 1AK7A 3CI5G 1VFQA 5KYWB 3FG6A 2XF1A 5KYWA 4CBXG 3EGDB 1T3XA 3A5LS 1Q8XA 1CNUA 2FH2A 3EG9B 1D0NA 3EG9A 2VIKA 1F7SA 1NPHA 1TMWA 1NLVG 1QPVA 2FGHA 3A5OS 4PKHB 1JHWA 2NUTB 3FFNA 2NUTA 1SVQA 2D8BA
chains in the Genus database with same CATH superfamily
1T44G 2NUPB 1C0FS 1P8XA 1PD1A 1C0GS 4BEX1 1SVRA 2FF3A 3FG7A 1J72A 1NM1G 2LJ8A 1AK6A 3EFOA 3CJBG 2XFAA 5FAFA 4KEDA 2L72A 2FH3A 2FH1A 5FAEA 3EGDA 3A5NS 4PKGG 1T3YA 4KEFA 5KYYB 3CIPG 2W0IA 1PCXA 1PD0A 1M2VB 4PKIG 1YAGG 1RGIG 4LIZA 1AHQA 3A5MS 5HVKD 5DD2A 1VKKA 2NUPA 5KYUB 4CBWG 2HD7A 5IVUA 1COFA 1ESVS 3L50A 3FFKA 2LXXA 2KVKA 3DA7A 1CFYA 5L6WC 1EQYS 1T2LA 1WM4A 5KYNA 1MDUA 4JD2H 5KYYA 2LLFA 3TU5B 1M2VA 4CBUG 1DEJS 5KYXB 4S10C 2MV2A 3Q2BA 1SVYA 1Q8GA 5KYUA 3DAWB 1M4JA 1P8ZG 2I2QA 2QTVA 1NMDG 3CJCG 1V6FA 3EH1A 3EGXB 1YVNG 3EGXA 2MOTA 2FH4A 1UDMA 4Z94G 5HVKB 1WFSA 1KCQA 1D4XG 1X67A 1WNJA 3EH2A 5A1MA 1HQZ1 2VILA 5KYXA 1M2OA 2VACA 2FF6G 2MP4A 4KEEA 3EFOB 1H1VG 1TVJA 1AK7A 3CI5G 1VFQA 5KYWB 3FG6A 2XF1A 5KYWA 4CBXG 3EGDB 1T3XA 3A5LS 1Q8XA 1CNUA 2FH2A 3EG9B 1D0NA 3EG9A 2VIKA 1F7SA 1NPHA 1TMWA 1NLVG 1QPVA 2FGHA 3A5OS 4PKHB 1JHWA 2NUTB 3FFNA 2NUTA 1SVQA 2D8BA
chains in the Genus database with same CATH topology
1T44G 2NUPB 1C0FS 1P8XA 1PD1A 1C0GS 4BEX1 1SVRA 2FF3A 3FG7A 1J72A 1NM1G 2LJ8A 1AK6A 3EFOA 3CJBG 2XFAA 5FAFA 4KEDA 2L72A 2FH3A 2FH1A 5FAEA 3EGDA 3A5NS 4PKGG 1T3YA 4KEFA 5KYYB 3CIPG 2W0IA 1PCXA 1PD0A 1M2VB 4PKIG 1YAGG 1RGIG 4LIZA 1AHQA 3A5MS 5HVKD 5DD2A 1VKKA 2NUPA 5KYUB 4CBWG 2HD7A 5IVUA 1COFA 1ESVS 3L50A 3FFKA 2LXXA 2KVKA 3DA7A 1CFYA 5L6WC 1EQYS 1T2LA 1WM4A 5KYNA 1MDUA 4JD2H 5KYYA 2LLFA 3TU5B 1M2VA 4CBUG 1DEJS 5KYXB 4S10C 2MV2A 3Q2BA 1SVYA 1Q8GA 5KYUA 3DAWB 1M4JA 1P8ZG 2I2QA 2QTVA 1NMDG 3CJCG 1V6FA 3EH1A 3EGXB 1YVNG 3EGXA 2MOTA 2FH4A 1UDMA 4Z94G 5HVKB 1WFSA 1KCQA 1D4XG 1X67A 1WNJA 3EH2A 5A1MA 1HQZ1 2VILA 5KYXA 1M2OA 2VACA 2FF6G 2MP4A 4KEEA 3EFOB 1H1VG 1TVJA 1AK7A 3CI5G 1VFQA 5KYWB 3FG6A 2XF1A 5KYWA 4CBXG 3EGDB 1T3XA 3A5LS 1Q8XA 1CNUA 2FH2A 3EG9B 1D0NA 3EG9A 2VIKA 1F7SA 1NPHA 1TMWA 1NLVG 1QPVA 2FGHA 3A5OS 4PKHB 1JHWA 2NUTB 3FFNA 2NUTA 1SVQA 2D8BA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1T44 G;  2NUP B;  1C0F S;  1P8X A;  1PD1 A;  1C0G S;  4BEX 1;  1SVR A;  2FF3 A;  3FG7 A;  1J72 A;  1NM1 G;  2LJ8 A;  1AK6 A;  3EFO A;  3CJB G;  2XFA A;  5FAF A;  4KED A;  2L72 A;  2FH3 A;  2FH1 A;  5FAE A;  3EGD A;  3A5N S;  4PKG G;  1T3Y A;  4KEF A;  5KYY B;  3CIP G;  2W0I A;  1PCX A;  1PD0 A;  1M2V B;  4PKI G;  1YAG G;  1RGI G;  4LIZ A;  1AHQ A;  3A5M S;  5HVK D;  5DD2 A;  1VKK A;  2NUP A;  5KYU B;  4CBW G;  2HD7 A;  5IVU A;  1COF A;  1ESV S;  3L50 A;  3FFK A;  2LXX A;  2KVK A;  1CFY A;  5L6W C;  1EQY S;  1T2L A;  1WM4 A;  5KYN A;  1MDU A;  4JD2 H;  5KYY A;  2LLF A;  3TU5 B;  1M2V A;  4CBU G;  1DEJ S;  5KYX B;  4S10 C;  2MV2 A;  3Q2B A;  1SVY A;  1Q8G A;  5KYU A;  3DAW B;  1M4J A;  1P8Z G;  2I2Q A;  2QTV A;  1NMD G;  3CJC G;  1V6F A;  3EH1 A;  3EGX B;  1YVN G;  3EGX A;  2MOT A;  2FH4 A;  1UDM A;  4Z94 G;  5HVK B;  1WFS A;  1KCQ A;  1D4X G;  1X67 A;  1WNJ A;  3EH2 A;  5A1M A;  1HQZ 1;  2VIL A;  5KYX A;  1M2O A;  2VAC A;  2FF6 G;  2MP4 A;  4KEE A;  3EFO B;  1H1V G;  1TVJ A;  1AK7 A;  3CI5 G;  1VFQ A;  5KYW B;  3FG6 A;  2XF1 A;  5KYW A;  4CBX G;  3EGD B;  1T3X A;  3A5L S;  1Q8X A;  1CNU A;  2FH2 A;  3EG9 B;  1D0N A;  3EG9 A;  2VIK A;  1F7S A;  1NPH A;  1TMW A;  1NLV G;  1QPV A;  2FGH A;  3A5O S;  4PKH B;  1JHW A;  2NUT B;  3FFN A;  2NUT A;  1SVQ A;  2D8B A; 
#chains in the Genus database with same CATH topology
 1T44 G;  2NUP B;  1C0F S;  1P8X A;  1PD1 A;  1C0G S;  4BEX 1;  1SVR A;  2FF3 A;  3FG7 A;  1J72 A;  1NM1 G;  2LJ8 A;  1AK6 A;  3EFO A;  3CJB G;  2XFA A;  5FAF A;  4KED A;  2L72 A;  2FH3 A;  2FH1 A;  5FAE A;  3EGD A;  3A5N S;  4PKG G;  1T3Y A;  4KEF A;  5KYY B;  3CIP G;  2W0I A;  1PCX A;  1PD0 A;  1M2V B;  4PKI G;  1YAG G;  1RGI G;  4LIZ A;  1AHQ A;  3A5M S;  5HVK D;  5DD2 A;  1VKK A;  2NUP A;  5KYU B;  4CBW G;  2HD7 A;  5IVU A;  1COF A;  1ESV S;  3L50 A;  3FFK A;  2LXX A;  2KVK A;  3DA7 A;  1CFY A;  5L6W C;  1EQY S;  1T2L A;  1WM4 A;  5KYN A;  1MDU A;  4JD2 H;  5KYY A;  2LLF A;  3TU5 B;  1M2V A;  4CBU G;  1DEJ S;  5KYX B;  4S10 C;  2MV2 A;  3Q2B A;  1SVY A;  1Q8G A;  5KYU A;  3DAW B;  1M4J A;  1P8Z G;  2I2Q A;  2QTV A;  1NMD G;  3CJC G;  1V6F A;  3EH1 A;  3EGX B;  1YVN G;  3EGX A;  2MOT A;  2FH4 A;  1UDM A;  4Z94 G;  5HVK B;  1WFS A;  1KCQ A;  1D4X G;  1X67 A;  1WNJ A;  3EH2 A;  5A1M A;  1HQZ 1;  2VIL A;  5KYX A;  1M2O A;  2VAC A;  2FF6 G;  2MP4 A;  4KEE A;  3EFO B;  1H1V G;  1TVJ A;  1AK7 A;  3CI5 G;  1VFQ A;  5KYW B;  3FG6 A;  2XF1 A;  5KYW A;  4CBX G;  3EGD B;  1T3X A;  3A5L S;  1Q8X A;  1CNU A;  2FH2 A;  3EG9 B;  1D0N A;  3EG9 A;  2VIK A;  1F7S A;  1NPH A;  1TMW A;  1NLV G;  1QPV A;  2FGH A;  3A5O S;  4PKH B;  1JHW A;  2NUT B;  3FFN A;  2NUT A;  1SVQ A;  2D8B A; 
#chains in the Genus database with same CATH homology
 1T44 G;  2NUP B;  1C0F S;  1P8X A;  1PD1 A;  1C0G S;  4BEX 1;  1SVR A;  2FF3 A;  3FG7 A;  1J72 A;  1NM1 G;  2LJ8 A;  1AK6 A;  3EFO A;  3CJB G;  2XFA A;  5FAF A;  4KED A;  2L72 A;  2FH3 A;  2FH1 A;  5FAE A;  3EGD A;  3A5N S;  4PKG G;  1T3Y A;  4KEF A;  5KYY B;  3CIP G;  2W0I A;  1PCX A;  1PD0 A;  1M2V B;  4PKI G;  1YAG G;  1RGI G;  4LIZ A;  1AHQ A;  3A5M S;  5HVK D;  5DD2 A;  1VKK A;  2NUP A;  5KYU B;  4CBW G;  2HD7 A;  5IVU A;  1COF A;  1ESV S;  3L50 A;  3FFK A;  2LXX A;  2KVK A;  3DA7 A;  1CFY A;  5L6W C;  1EQY S;  1T2L A;  1WM4 A;  5KYN A;  1MDU A;  4JD2 H;  5KYY A;  2LLF A;  3TU5 B;  1M2V A;  4CBU G;  1DEJ S;  5KYX B;  4S10 C;  2MV2 A;  3Q2B A;  1SVY A;  1Q8G A;  5KYU A;  3DAW B;  1M4J A;  1P8Z G;  2I2Q A;  2QTV A;  1NMD G;  3CJC G;  1V6F A;  3EH1 A;  3EGX B;  1YVN G;  3EGX A;  2MOT A;  2FH4 A;  1UDM A;  4Z94 G;  5HVK B;  1WFS A;  1KCQ A;  1D4X G;  1X67 A;  1WNJ A;  3EH2 A;  5A1M A;  1HQZ 1;  2VIL A;  5KYX A;  1M2O A;  2VAC A;  2FF6 G;  2MP4 A;  4KEE A;  3EFO B;  1H1V G;  1TVJ A;  1AK7 A;  3CI5 G;  1VFQ A;  5KYW B;  3FG6 A;  2XF1 A;  5KYW A;  4CBX G;  3EGD B;  1T3X A;  3A5L S;  1Q8X A;  1CNU A;  2FH2 A;  3EG9 B;  1D0N A;  3EG9 A;  2VIK A;  1F7S A;  1NPH A;  1TMW A;  1NLV G;  1QPV A;  2FGH A;  3A5O S;  4PKH B;  1JHW A;  2NUT B;  3FFN A;  2NUT A;  1SVQ A;  2D8B A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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