The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
205
|
sequence length |
762
|
structure length |
708
|
Chain Sequence |
TYLEFIQQNEERDGVRFSWNVWPSSRLEATRMVVPVAALFTPLKERPDLPPIQYEPVLCSRTTCRAVLNPLCQVDYRAKLWACNFCYQRNQFPPSYAGISELNQPAELLPQFSSIEYVVLRGPQMPLIFLYVVDTCMEDEDLQALKESMQMSLSLLPPTALVGLITFGRMVQVHELGCEGISKSYVFRGTKDLSAKQLQEMLGPSNRFLQPVQKIDMNLTDLLGELQRDPWPVPQGKRPLRSSGVALSIAVGLLECTFPNTGARIMMFIGGPATQGPGMVVGDELKTPIRSWHDIDKDNAKYVKKGTKHFEALANRAATTGHVIDIYACALDQTGLLEMKCCPNLTGGYMVMGDSFNTSLFKQTFQRVFTKDMHGQFKMGFGGTLEIKTSREIKISGAIGPCVSLNSKGPCVSENEIGTGGTCQWKICGLSPTTTLAIYFEVVGRGAIQFVTQYQHSSGQRRIRVTTIARNWADAQTQIQNIAASFDQEAAAILMARLAIYRAETEDVLRWLDRQLIRLCQKFGEYHKDDPSSFRFSETFSLYPQFMFHLRRSSFLQVFNNSPDESSYYRHHFMRQDLTQSLIMIQPILYAYSFSGPPEPVLLDSSSILADRILLMDTFFQILIYHGETIAQWRKSGYQDMPEYENFRHLLQAPVDDAQEILHSRFPMPRYIDTEHGGSQARFLLSKVNDVSLQVFMDHLKKLAVSSA
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Structural basis of cargo membrane protein discrimination by the human COPII coat machinery.
pubmed doi rcsb |
| molecule tags |
Protein transport
|
| source organism |
Homo sapiens
|
| molecule keywords |
Protein transport protein Sec23A
|
| total genus |
205
|
| structure length |
708
|
| sequence length |
762
|
| ec nomenclature | |
| pdb deposition date | 2008-09-11 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF00626 | Gelsolin | Gelsolin repeat |
| A | PF04810 | zf-Sec23_Sec24 | Sec23/Sec24 zinc finger |
| A | PF04811 | Sec23_trunk | Sec23/Sec24 trunk domain |
| A | PF04815 | Sec23_helical | Sec23/Sec24 helical domain |
| A | PF08033 | Sec23_BS | Sec23/Sec24 beta-sandwich domain |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Alpha | Up-down Bundle | Four Helix Bundle (Hemerythrin (Met), subunit A) | Four Helix Bundle (Hemerythrin (Met), subunit A) | ||
| Mainly Beta | Roll | SH3 type barrels. | Zn-finger domain of Sec23/24 | ||
| Mainly Beta | Sandwich | Immunoglobulin-like | beta-sandwich domain of Sec23/24 | ||
| Alpha Beta | 3-Layer(aba) Sandwich | Severin | Severin | ||
| Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | von Willebrand factor, type A domain |
