1RGIG

Crystal structure of gelsolin domains g1-g3 bound to actin
Total Genus 101
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
101
sequence length
346
structure length
346
Chain Sequence
VVEHPEFLKAGKEPGLQIWRVEKFDLVPVPPNLYGDFFTGDAYVILKTVQLRNGILQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGFKHVVPNEVVVQRLLQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIYQWCGSKSNRFERLKATQVSKGIRDNERSGRAQVSVFEEGAEPEAMLQVLGPKPTLPEATEDTVKEDAANRKLAKLYKVSNGAGPMVVSLVADENPFAQGALRSEDCFILDHGKDGKIFVWKGKQANMEERKAALKTASDFISKMDYPKQTQVSVLPEGGETPLFRQFFKNWRD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the N-terminal half of gelsolin bound to actin: roles in severing, apoptosis and FAF
pubmed doi rcsb
molecule tags Contractile protein
molecule keywords Gelsolin
total genus 101
structure length 346
sequence length 346
ec nomenclature
pdb deposition date 2003-11-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
G PF00626 Gelsolin Gelsolin repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 1rgiG02
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 1rgiG01
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 1rgiG03
3EH2A 5L6WC 5KYUA 1T3YA 1T44G 3EGXB 3EG9A 4LIZA 5IVUA 4JD2H 2NUPA 1YVNG 1SVQA 1PCXA 2FH3A 3EGDA 1T3XA 5FAFA 2MOTA 1CFYA 2NUTA 5KYYA 4PKIG 3TU5B 2VILA 1WNJA 1TVJA 4PKHB 1C0GS 1J72A 1Q8GA 3FFNA 4CBXG 4CBWG 1M2OA 5A1MA 1NMDG 3EFOB 5HVKD 2FF3A 1JHWA 4KEFA 1SVRA 3DAWB 2MV2A 5KYUB 1AK6A 3EG9B 1NLVG 3EH1A 1M2VA 2W0IA 1WM4A 1DEJS 3A5MS 2NUPB 1QPVA 1SVYA 1KCQA 2XF1A 5HVKB 3FFKA 4S10C 2LLFA 2NUTB 4BEX1 5KYYB 2XFAA 3CJBG 1D4XG 1AHQA 5FAEA 1MDUA 1C0FS 3L50A 2FH4A 2VIKA 2QTVA 1M4JA 1H1VG 1AK7A 1VKKA 3CI5G 1ESVS 3FG7A 3Q2BA 5KYXA 1M2VB 3EGDB 2L72A 1PD0A 1CNUA 1Q8XA 1P8XA 1D0NA 5KYWA 2FF6G 1WFSA 2FH1A 2I2QA 5DD2A 1F7SA 3EGXA 3A5OS 1NPHA 2LXXA 5KYNA 1PD1A 4KEEA 3CJCG 3A5NS 2VACA 1COFA 3CIPG 4PKGG 1UDMA 1HQZ1 2D8BA 2FH2A 2HD7A 1X67A 4KEDA 5KYXB 1T2LA 2KVKA 3A5LS 1TMWA 4CBUG 1V6FA 4Z94G 2FGHA 1EQYS 5KYWB 3FG6A 2MP4A 1YAGG 2LJ8A 3EFOA 1VFQA 1NM1G 1RGIG 1P8ZG
chains in the Genus database with same CATH superfamily
3EH2A 5L6WC 5KYUA 1T3YA 1T44G 3EGXB 3EG9A 4LIZA 5IVUA 4JD2H 2NUPA 1YVNG 1SVQA 1PCXA 2FH3A 3EGDA 1T3XA 5FAFA 2MOTA 1CFYA 2NUTA 5KYYA 4PKIG 3TU5B 2VILA 1WNJA 1TVJA 4PKHB 1C0GS 1J72A 1Q8GA 3FFNA 4CBXG 4CBWG 1M2OA 5A1MA 1NMDG 3EFOB 5HVKD 2FF3A 1JHWA 4KEFA 1SVRA 3DAWB 2MV2A 5KYUB 1AK6A 3EG9B 1NLVG 3EH1A 1M2VA 2W0IA 1WM4A 1DEJS 3A5MS 2NUPB 1QPVA 1SVYA 1KCQA 2XF1A 5HVKB 3FFKA 4S10C 2LLFA 2NUTB 4BEX1 5KYYB 2XFAA 3CJBG 1D4XG 1AHQA 5FAEA 1MDUA 1C0FS 3DA7A 3L50A 2FH4A 2VIKA 2QTVA 1M4JA 1H1VG 1AK7A 1VKKA 3CI5G 1ESVS 3FG7A 3Q2BA 5KYXA 1M2VB 3EGDB 2L72A 1PD0A 1CNUA 1Q8XA 1P8XA 1D0NA 5KYWA 2FF6G 1WFSA 2FH1A 2I2QA 5DD2A 1F7SA 3EGXA 3A5OS 1NPHA 2LXXA 5KYNA 1PD1A 4KEEA 3CJCG 3A5NS 2VACA 1COFA 3CIPG 4PKGG 1UDMA 1HQZ1 2D8BA 2FH2A 2HD7A 1X67A 4KEDA 5KYXB 1T2LA 2KVKA 3A5LS 1TMWA 4CBUG 1V6FA 4Z94G 2FGHA 1EQYS 5KYWB 3FG6A 2MP4A 1YAGG 2LJ8A 3EFOA 1VFQA 1NM1G 1RGIG 1P8ZG
chains in the Genus database with same CATH topology
3EH2A 5L6WC 5KYUA 1T3YA 1T44G 3EGXB 3EG9A 4LIZA 5IVUA 4JD2H 2NUPA 1YVNG 1SVQA 1PCXA 2FH3A 3EGDA 1T3XA 5FAFA 2MOTA 1CFYA 2NUTA 5KYYA 4PKIG 3TU5B 2VILA 1WNJA 1TVJA 4PKHB 1C0GS 1J72A 1Q8GA 3FFNA 4CBXG 4CBWG 1M2OA 5A1MA 1NMDG 3EFOB 5HVKD 2FF3A 1JHWA 4KEFA 1SVRA 3DAWB 2MV2A 5KYUB 1AK6A 3EG9B 1NLVG 3EH1A 1M2VA 2W0IA 1WM4A 1DEJS 3A5MS 2NUPB 1QPVA 1SVYA 1KCQA 2XF1A 5HVKB 3FFKA 4S10C 2LLFA 2NUTB 4BEX1 5KYYB 2XFAA 3CJBG 1D4XG 1AHQA 5FAEA 1MDUA 1C0FS 3DA7A 3L50A 2FH4A 2VIKA 2QTVA 1M4JA 1H1VG 1AK7A 1VKKA 3CI5G 1ESVS 3FG7A 3Q2BA 5KYXA 1M2VB 3EGDB 2L72A 1PD0A 1CNUA 1Q8XA 1P8XA 1D0NA 5KYWA 2FF6G 1WFSA 2FH1A 2I2QA 5DD2A 1F7SA 3EGXA 3A5OS 1NPHA 2LXXA 5KYNA 1PD1A 4KEEA 3CJCG 3A5NS 2VACA 1COFA 3CIPG 4PKGG 1UDMA 1HQZ1 2D8BA 2FH2A 2HD7A 1X67A 4KEDA 5KYXB 1T2LA 2KVKA 3A5LS 1TMWA 4CBUG 1V6FA 4Z94G 2FGHA 1EQYS 5KYWB 3FG6A 2MP4A 1YAGG 2LJ8A 3EFOA 1VFQA 1NM1G 1RGIG 1P8ZG
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3EH2 A;  5L6W C;  5KYU A;  1T3Y A;  1T44 G;  3EGX B;  3EG9 A;  4LIZ A;  5IVU A;  4JD2 H;  2NUP A;  1YVN G;  1SVQ A;  1PCX A;  2FH3 A;  3EGD A;  1T3X A;  5FAF A;  2MOT A;  1CFY A;  2NUT A;  5KYY A;  4PKI G;  3TU5 B;  2VIL A;  1WNJ A;  1TVJ A;  4PKH B;  1C0G S;  1J72 A;  1Q8G A;  3FFN A;  4CBX G;  4CBW G;  1M2O A;  5A1M A;  1NMD G;  3EFO B;  5HVK D;  2FF3 A;  1JHW A;  4KEF A;  1SVR A;  3DAW B;  2MV2 A;  5KYU B;  1AK6 A;  3EG9 B;  1NLV G;  3EH1 A;  1M2V A;  2W0I A;  1WM4 A;  1DEJ S;  3A5M S;  2NUP B;  1QPV A;  1SVY A;  1KCQ A;  2XF1 A;  5HVK B;  3FFK A;  4S10 C;  2LLF A;  2NUT B;  4BEX 1;  5KYY B;  2XFA A;  3CJB G;  1D4X G;  1AHQ A;  5FAE A;  1MDU A;  1C0F S;  3L50 A;  2FH4 A;  2VIK A;  2QTV A;  1M4J A;  1H1V G;  1AK7 A;  1VKK A;  3CI5 G;  1ESV S;  3FG7 A;  3Q2B A;  5KYX A;  1M2V B;  3EGD B;  2L72 A;  1PD0 A;  1CNU A;  1Q8X A;  1P8X A;  1D0N A;  5KYW A;  2FF6 G;  1WFS A;  2FH1 A;  2I2Q A;  5DD2 A;  1F7S A;  3EGX A;  3A5O S;  1NPH A;  2LXX A;  5KYN A;  1PD1 A;  4KEE A;  3CJC G;  3A5N S;  2VAC A;  1COF A;  3CIP G;  4PKG G;  1UDM A;  1HQZ 1;  2D8B A;  2FH2 A;  2HD7 A;  1X67 A;  4KED A;  5KYX B;  1T2L A;  2KVK A;  3A5L S;  1TMW A;  4CBU G;  1V6F A;  4Z94 G;  2FGH A;  1EQY S;  5KYW B;  3FG6 A;  2MP4 A;  1YAG G;  2LJ8 A;  3EFO A;  1VFQ A;  1NM1 G;  1RGI G;  1P8Z G; 
#chains in the Genus database with same CATH topology
 3EH2 A;  5L6W C;  5KYU A;  1T3Y A;  1T44 G;  3EGX B;  3EG9 A;  4LIZ A;  5IVU A;  4JD2 H;  2NUP A;  1YVN G;  1SVQ A;  1PCX A;  2FH3 A;  3EGD A;  1T3X A;  5FAF A;  2MOT A;  1CFY A;  2NUT A;  5KYY A;  4PKI G;  3TU5 B;  2VIL A;  1WNJ A;  1TVJ A;  4PKH B;  1C0G S;  1J72 A;  1Q8G A;  3FFN A;  4CBX G;  4CBW G;  1M2O A;  5A1M A;  1NMD G;  3EFO B;  5HVK D;  2FF3 A;  1JHW A;  4KEF A;  1SVR A;  3DAW B;  2MV2 A;  5KYU B;  1AK6 A;  3EG9 B;  1NLV G;  3EH1 A;  1M2V A;  2W0I A;  1WM4 A;  1DEJ S;  3A5M S;  2NUP B;  1QPV A;  1SVY A;  1KCQ A;  2XF1 A;  5HVK B;  3FFK A;  4S10 C;  2LLF A;  2NUT B;  4BEX 1;  5KYY B;  2XFA A;  3CJB G;  1D4X G;  1AHQ A;  5FAE A;  1MDU A;  1C0F S;  3DA7 A;  3L50 A;  2FH4 A;  2VIK A;  2QTV A;  1M4J A;  1H1V G;  1AK7 A;  1VKK A;  3CI5 G;  1ESV S;  3FG7 A;  3Q2B A;  5KYX A;  1M2V B;  3EGD B;  2L72 A;  1PD0 A;  1CNU A;  1Q8X A;  1P8X A;  1D0N A;  5KYW A;  2FF6 G;  1WFS A;  2FH1 A;  2I2Q A;  5DD2 A;  1F7S A;  3EGX A;  3A5O S;  1NPH A;  2LXX A;  5KYN A;  1PD1 A;  4KEE A;  3CJC G;  3A5N S;  2VAC A;  1COF A;  3CIP G;  4PKG G;  1UDM A;  1HQZ 1;  2D8B A;  2FH2 A;  2HD7 A;  1X67 A;  4KED A;  5KYX B;  1T2L A;  2KVK A;  3A5L S;  1TMW A;  4CBU G;  1V6F A;  4Z94 G;  2FGH A;  1EQY S;  5KYW B;  3FG6 A;  2MP4 A;  1YAG G;  2LJ8 A;  3EFO A;  1VFQ A;  1NM1 G;  1RGI G;  1P8Z G; 
#chains in the Genus database with same CATH homology
 3EH2 A;  5L6W C;  5KYU A;  1T3Y A;  1T44 G;  3EGX B;  3EG9 A;  4LIZ A;  5IVU A;  4JD2 H;  2NUP A;  1YVN G;  1SVQ A;  1PCX A;  2FH3 A;  3EGD A;  1T3X A;  5FAF A;  2MOT A;  1CFY A;  2NUT A;  5KYY A;  4PKI G;  3TU5 B;  2VIL A;  1WNJ A;  1TVJ A;  4PKH B;  1C0G S;  1J72 A;  1Q8G A;  3FFN A;  4CBX G;  4CBW G;  1M2O A;  5A1M A;  1NMD G;  3EFO B;  5HVK D;  2FF3 A;  1JHW A;  4KEF A;  1SVR A;  3DAW B;  2MV2 A;  5KYU B;  1AK6 A;  3EG9 B;  1NLV G;  3EH1 A;  1M2V A;  2W0I A;  1WM4 A;  1DEJ S;  3A5M S;  2NUP B;  1QPV A;  1SVY A;  1KCQ A;  2XF1 A;  5HVK B;  3FFK A;  4S10 C;  2LLF A;  2NUT B;  4BEX 1;  5KYY B;  2XFA A;  3CJB G;  1D4X G;  1AHQ A;  5FAE A;  1MDU A;  1C0F S;  3DA7 A;  3L50 A;  2FH4 A;  2VIK A;  2QTV A;  1M4J A;  1H1V G;  1AK7 A;  1VKK A;  3CI5 G;  1ESV S;  3FG7 A;  3Q2B A;  5KYX A;  1M2V B;  3EGD B;  2L72 A;  1PD0 A;  1CNU A;  1Q8X A;  1P8X A;  1D0N A;  5KYW A;  2FF6 G;  1WFS A;  2FH1 A;  2I2Q A;  5DD2 A;  1F7S A;  3EGX A;  3A5O S;  1NPH A;  2LXX A;  5KYN A;  1PD1 A;  4KEE A;  3CJC G;  3A5N S;  2VAC A;  1COF A;  3CIP G;  4PKG G;  1UDM A;  1HQZ 1;  2D8B A;  2FH2 A;  2HD7 A;  1X67 A;  4KED A;  5KYX B;  1T2L A;  2KVK A;  3A5L S;  1TMW A;  4CBU G;  1V6F A;  4Z94 G;  2FGH A;  1EQY S;  5KYW B;  3FG6 A;  2MP4 A;  1YAG G;  2LJ8 A;  3EFO A;  1VFQ A;  1NM1 G;  1RGI G;  1P8Z G; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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