1RGIG

Crystal structure of gelsolin domains g1-g3 bound to actin
Total Genus 101
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
101
sequence length
346
structure length
346
Chain Sequence
VVEHPEFLKAGKEPGLQIWRVEKFDLVPVPPNLYGDFFTGDAYVILKTVQLRNGILQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGFKHVVPNEVVVQRLLQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIYQWCGSKSNRFERLKATQVSKGIRDNERSGRAQVSVFEEGAEPEAMLQVLGPKPTLPEATEDTVKEDAANRKLAKLYKVSNGAGPMVVSLVADENPFAQGALRSEDCFILDHGKDGKIFVWKGKQANMEERKAALKTASDFISKMDYPKQTQVSVLPEGGETPLFRQFFKNWRD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structure of the N-terminal half of gelsolin bound to actin: roles in severing, apoptosis and FAF
pubmed doi rcsb
molecule tags Contractile protein
molecule keywords Gelsolin
total genus 101
structure length 346
sequence length 346
ec nomenclature
pdb deposition date 2003-11-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
G PF00626 Gelsolin Gelsolin repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 1rgiG02
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 1rgiG01
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 1rgiG03
2HD7A 1NLVG 3L50A 3A5NS 5KYXA 1P8ZG 4CBUG 1D0NA 2VILA 3EGXA 1H1VG 1YVNG 2NUTA 1NM1G 2L72A 4PKHB 1T3YA 1J72A 3A5OS 5L6WC 1M2OA 1NMDG 1ESVS 1Q8XA 1COFA 3EG9B 1C0FS 4LIZA 1MDUA 1T2LA 1T3XA 5KYYA 3DAWB 3EFOA 2LLFA 3Q2BA 4KEEA 5A1MA 1SVRA 3FFKA 3EGDA 2FGHA 1WNJA 1P8XA 1M4JA 2LXXA 3A5LS 3FG6A 3EGDB 1DEJS 2FH4A 4PKIG 2VIKA 2LJ8A 1F7SA 2NUPA 5FAEA 1PD0A 1CNUA 4JD2H 1WM4A 3A5MS 1M2VB 1CFYA 4BEX1 5KYWA 1AHQA 5KYWB 1QPVA 1SVYA 1AK7A 5KYUB 3TU5B 2KVKA 1WFSA 5KYUA 1VKKA 5KYXB 2XFAA 3EH2A 2FF3A 5DD2A 3FG7A 5IVUA 2FH3A 1RGIG 5HVKD 3CI5G 2QTVA 2MOTA 1HQZ1 2NUTB 3FFNA 4KEFA 5HVKB 1M2VA 2W0IA 2FH1A 1TVJA 1NPHA 2FH2A 2FF6G 2XF1A 4S10C 2I2QA 1JHWA 3CJCG 1EQYS 4Z94G 3EFOB 3CJBG 1X67A 2D8BA 3EGXB 1V6FA 1C0GS 1Q8GA 1T44G 1KCQA 2NUPB 5FAFA 2MP4A 2VACA 3EH1A 5KYNA 1PCXA 2MV2A 1VFQA 3CIPG 3EG9A 1D4XG 4CBWG 1TMWA 1YAGG 1SVQA 1PD1A 5KYYB 1AK6A 4CBXG 4KEDA 1UDMA 4PKGG
chains in the Genus database with same CATH superfamily
2HD7A 1NLVG 3L50A 3A5NS 5KYXA 1P8ZG 4CBUG 1D0NA 2VILA 3EGXA 1H1VG 1YVNG 2NUTA 1NM1G 2L72A 4PKHB 1T3YA 1J72A 3A5OS 5L6WC 1M2OA 1NMDG 1ESVS 1Q8XA 1COFA 3EG9B 1C0FS 4LIZA 1MDUA 1T2LA 1T3XA 5KYYA 3DAWB 3EFOA 2LLFA 3Q2BA 4KEEA 5A1MA 1SVRA 3FFKA 3EGDA 2FGHA 1WNJA 1P8XA 1M4JA 2LXXA 3A5LS 3FG6A 3EGDB 1DEJS 2FH4A 4PKIG 2VIKA 2LJ8A 1F7SA 2NUPA 5FAEA 1PD0A 1CNUA 4JD2H 1WM4A 3A5MS 1M2VB 1CFYA 4BEX1 5KYWA 1AHQA 3DA7A 5KYWB 1QPVA 1SVYA 1AK7A 5KYUB 3TU5B 2KVKA 1WFSA 5KYUA 1VKKA 5KYXB 2XFAA 3EH2A 2FF3A 5DD2A 3FG7A 5IVUA 2FH3A 1RGIG 5HVKD 3CI5G 2QTVA 2MOTA 1HQZ1 2NUTB 3FFNA 4KEFA 5HVKB 1M2VA 2W0IA 2FH1A 1TVJA 1NPHA 2FH2A 2FF6G 2XF1A 4S10C 2I2QA 1JHWA 3CJCG 1EQYS 4Z94G 3EFOB 3CJBG 1X67A 2D8BA 3EGXB 1V6FA 1C0GS 1Q8GA 1T44G 1KCQA 2NUPB 5FAFA 2MP4A 2VACA 3EH1A 5KYNA 1PCXA 2MV2A 1VFQA 3CIPG 3EG9A 1D4XG 4CBWG 1TMWA 1YAGG 1SVQA 1PD1A 5KYYB 1AK6A 4CBXG 4KEDA 1UDMA 4PKGG
chains in the Genus database with same CATH topology
2HD7A 1NLVG 3L50A 3A5NS 5KYXA 1P8ZG 4CBUG 1D0NA 2VILA 3EGXA 1H1VG 1YVNG 2NUTA 1NM1G 2L72A 4PKHB 1T3YA 1J72A 3A5OS 5L6WC 1M2OA 1NMDG 1ESVS 1Q8XA 1COFA 3EG9B 1C0FS 4LIZA 1MDUA 1T2LA 1T3XA 5KYYA 3DAWB 3EFOA 2LLFA 3Q2BA 4KEEA 5A1MA 1SVRA 3FFKA 3EGDA 2FGHA 1WNJA 1P8XA 1M4JA 2LXXA 3A5LS 3FG6A 3EGDB 1DEJS 2FH4A 4PKIG 2VIKA 2LJ8A 1F7SA 2NUPA 5FAEA 1PD0A 1CNUA 4JD2H 1WM4A 3A5MS 1M2VB 1CFYA 4BEX1 5KYWA 1AHQA 3DA7A 5KYWB 1QPVA 1SVYA 1AK7A 5KYUB 3TU5B 2KVKA 1WFSA 5KYUA 1VKKA 5KYXB 2XFAA 3EH2A 2FF3A 5DD2A 3FG7A 5IVUA 2FH3A 1RGIG 5HVKD 3CI5G 2QTVA 2MOTA 1HQZ1 2NUTB 3FFNA 4KEFA 5HVKB 1M2VA 2W0IA 2FH1A 1TVJA 1NPHA 2FH2A 2FF6G 2XF1A 4S10C 2I2QA 1JHWA 3CJCG 1EQYS 4Z94G 3EFOB 3CJBG 1X67A 2D8BA 3EGXB 1V6FA 1C0GS 1Q8GA 1T44G 1KCQA 2NUPB 5FAFA 2MP4A 2VACA 3EH1A 5KYNA 1PCXA 2MV2A 1VFQA 3CIPG 3EG9A 1D4XG 4CBWG 1TMWA 1YAGG 1SVQA 1PD1A 5KYYB 1AK6A 4CBXG 4KEDA 1UDMA 4PKGG
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2HD7 A;  1NLV G;  3L50 A;  3A5N S;  5KYX A;  1P8Z G;  4CBU G;  1D0N A;  2VIL A;  3EGX A;  1H1V G;  1YVN G;  2NUT A;  1NM1 G;  2L72 A;  4PKH B;  1T3Y A;  1J72 A;  3A5O S;  5L6W C;  1M2O A;  1NMD G;  1ESV S;  1Q8X A;  1COF A;  3EG9 B;  1C0F S;  4LIZ A;  1MDU A;  1T2L A;  1T3X A;  5KYY A;  3DAW B;  3EFO A;  2LLF A;  3Q2B A;  4KEE A;  5A1M A;  1SVR A;  3FFK A;  3EGD A;  2FGH A;  1WNJ A;  1P8X A;  1M4J A;  2LXX A;  3A5L S;  3FG6 A;  3EGD B;  1DEJ S;  2FH4 A;  4PKI G;  2VIK A;  2LJ8 A;  1F7S A;  2NUP A;  5FAE A;  1PD0 A;  1CNU A;  4JD2 H;  1WM4 A;  3A5M S;  1M2V B;  1CFY A;  4BEX 1;  5KYW A;  1AHQ A;  5KYW B;  1QPV A;  1SVY A;  1AK7 A;  5KYU B;  3TU5 B;  2KVK A;  1WFS A;  5KYU A;  1VKK A;  5KYX B;  2XFA A;  3EH2 A;  2FF3 A;  5DD2 A;  3FG7 A;  5IVU A;  2FH3 A;  1RGI G;  5HVK D;  3CI5 G;  2QTV A;  2MOT A;  1HQZ 1;  2NUT B;  3FFN A;  4KEF A;  5HVK B;  1M2V A;  2W0I A;  2FH1 A;  1TVJ A;  1NPH A;  2FH2 A;  2FF6 G;  2XF1 A;  4S10 C;  2I2Q A;  1JHW A;  3CJC G;  1EQY S;  4Z94 G;  3EFO B;  3CJB G;  1X67 A;  2D8B A;  3EGX B;  1V6F A;  1C0G S;  1Q8G A;  1T44 G;  1KCQ A;  2NUP B;  5FAF A;  2MP4 A;  2VAC A;  3EH1 A;  5KYN A;  1PCX A;  2MV2 A;  1VFQ A;  3CIP G;  3EG9 A;  1D4X G;  4CBW G;  1TMW A;  1YAG G;  1SVQ A;  1PD1 A;  5KYY B;  1AK6 A;  4CBX G;  4KED A;  1UDM A;  4PKG G; 
#chains in the Genus database with same CATH topology
 2HD7 A;  1NLV G;  3L50 A;  3A5N S;  5KYX A;  1P8Z G;  4CBU G;  1D0N A;  2VIL A;  3EGX A;  1H1V G;  1YVN G;  2NUT A;  1NM1 G;  2L72 A;  4PKH B;  1T3Y A;  1J72 A;  3A5O S;  5L6W C;  1M2O A;  1NMD G;  1ESV S;  1Q8X A;  1COF A;  3EG9 B;  1C0F S;  4LIZ A;  1MDU A;  1T2L A;  1T3X A;  5KYY A;  3DAW B;  3EFO A;  2LLF A;  3Q2B A;  4KEE A;  5A1M A;  1SVR A;  3FFK A;  3EGD A;  2FGH A;  1WNJ A;  1P8X A;  1M4J A;  2LXX A;  3A5L S;  3FG6 A;  3EGD B;  1DEJ S;  2FH4 A;  4PKI G;  2VIK A;  2LJ8 A;  1F7S A;  2NUP A;  5FAE A;  1PD0 A;  1CNU A;  4JD2 H;  1WM4 A;  3A5M S;  1M2V B;  1CFY A;  4BEX 1;  5KYW A;  1AHQ A;  3DA7 A;  5KYW B;  1QPV A;  1SVY A;  1AK7 A;  5KYU B;  3TU5 B;  2KVK A;  1WFS A;  5KYU A;  1VKK A;  5KYX B;  2XFA A;  3EH2 A;  2FF3 A;  5DD2 A;  3FG7 A;  5IVU A;  2FH3 A;  1RGI G;  5HVK D;  3CI5 G;  2QTV A;  2MOT A;  1HQZ 1;  2NUT B;  3FFN A;  4KEF A;  5HVK B;  1M2V A;  2W0I A;  2FH1 A;  1TVJ A;  1NPH A;  2FH2 A;  2FF6 G;  2XF1 A;  4S10 C;  2I2Q A;  1JHW A;  3CJC G;  1EQY S;  4Z94 G;  3EFO B;  3CJB G;  1X67 A;  2D8B A;  3EGX B;  1V6F A;  1C0G S;  1Q8G A;  1T44 G;  1KCQ A;  2NUP B;  5FAF A;  2MP4 A;  2VAC A;  3EH1 A;  5KYN A;  1PCX A;  2MV2 A;  1VFQ A;  3CIP G;  3EG9 A;  1D4X G;  4CBW G;  1TMW A;  1YAG G;  1SVQ A;  1PD1 A;  5KYY B;  1AK6 A;  4CBX G;  4KED A;  1UDM A;  4PKG G; 
#chains in the Genus database with same CATH homology
 2HD7 A;  1NLV G;  3L50 A;  3A5N S;  5KYX A;  1P8Z G;  4CBU G;  1D0N A;  2VIL A;  3EGX A;  1H1V G;  1YVN G;  2NUT A;  1NM1 G;  2L72 A;  4PKH B;  1T3Y A;  1J72 A;  3A5O S;  5L6W C;  1M2O A;  1NMD G;  1ESV S;  1Q8X A;  1COF A;  3EG9 B;  1C0F S;  4LIZ A;  1MDU A;  1T2L A;  1T3X A;  5KYY A;  3DAW B;  3EFO A;  2LLF A;  3Q2B A;  4KEE A;  5A1M A;  1SVR A;  3FFK A;  3EGD A;  2FGH A;  1WNJ A;  1P8X A;  1M4J A;  2LXX A;  3A5L S;  3FG6 A;  3EGD B;  1DEJ S;  2FH4 A;  4PKI G;  2VIK A;  2LJ8 A;  1F7S A;  2NUP A;  5FAE A;  1PD0 A;  1CNU A;  4JD2 H;  1WM4 A;  3A5M S;  1M2V B;  1CFY A;  4BEX 1;  5KYW A;  1AHQ A;  3DA7 A;  5KYW B;  1QPV A;  1SVY A;  1AK7 A;  5KYU B;  3TU5 B;  2KVK A;  1WFS A;  5KYU A;  1VKK A;  5KYX B;  2XFA A;  3EH2 A;  2FF3 A;  5DD2 A;  3FG7 A;  5IVU A;  2FH3 A;  1RGI G;  5HVK D;  3CI5 G;  2QTV A;  2MOT A;  1HQZ 1;  2NUT B;  3FFN A;  4KEF A;  5HVK B;  1M2V A;  2W0I A;  2FH1 A;  1TVJ A;  1NPH A;  2FH2 A;  2FF6 G;  2XF1 A;  4S10 C;  2I2Q A;  1JHW A;  3CJC G;  1EQY S;  4Z94 G;  3EFO B;  3CJB G;  1X67 A;  2D8B A;  3EGX B;  1V6F A;  1C0G S;  1Q8G A;  1T44 G;  1KCQ A;  2NUP B;  5FAF A;  2MP4 A;  2VAC A;  3EH1 A;  5KYN A;  1PCX A;  2MV2 A;  1VFQ A;  3CIP G;  3EG9 A;  1D4X G;  4CBW G;  1TMW A;  1YAG G;  1SVQ A;  1PD1 A;  5KYY B;  1AK6 A;  4CBX G;  4KED A;  1UDM A;  4PKG G; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...