1RGIG

Crystal structure of gelsolin domains g1-g3 bound to actin
Total Genus 101
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
101
sequence length
346
structure length
346
Chain Sequence
VVEHPEFLKAGKEPGLQIWRVEKFDLVPVPPNLYGDFFTGDAYVILKTVQLRNGILQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGFKHVVPNEVVVQRLLQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIYQWCGSKSNRFERLKATQVSKGIRDNERSGRAQVSVFEEGAEPEAMLQVLGPKPTLPEATEDTVKEDAANRKLAKLYKVSNGAGPMVVSLVADENPFAQGALRSEDCFILDHGKDGKIFVWKGKQANMEERKAALKTASDFISKMDYPKQTQVSVLPEGGETPLFRQFFKNWRD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the N-terminal half of gelsolin bound to actin: roles in severing, apoptosis and FAF
pubmed doi rcsb
molecule tags Contractile protein
molecule keywords Gelsolin
total genus 101
structure length 346
sequence length 346
ec nomenclature
pdb deposition date 2003-11-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
G PF00626 Gelsolin Gelsolin repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 1rgiG02
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 1rgiG01
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 1rgiG03
1NLVG 1TVJA 2LJ8A 1V6FA 2HD7A 2XFAA 1WFSA 1Q8GA 5A1MA 3EH1A 2FH4A 5KYXA 5KYWA 1F7SA 2NUTB 1VKKA 2NUTA 2FGHA 1P8XA 4PKIG 1NPHA 1CFYA 1AHQA 2VILA 3EFOA 1PD1A 4S10C 1P8ZG 1X67A 1SVQA 2LLFA 1T2LA 5KYUA 1AK7A 1QPVA 1JHWA 1C0GS 3CIPG 5KYYB 1PCXA 1MDUA 1WNJA 3EGDA 1SVYA 2NUPA 1SVRA 3EH2A 5FAEA 2KVKA 4CBXG 1ESVS 2NUPB 1DEJS 3FFKA 1T44G 3TU5B 5DD2A 2W0IA 3FG7A 3A5NS 5KYUB 3EGXA 1TMWA 2FH1A 1EQYS 1VFQA 3EG9B 4PKGG 3FG6A 5HVKB 5KYYA 1C0FS 3FFNA 3A5OS 1D4XG 2FH3A 4KEFA 5KYNA 1YAGG 2QTVA 1T3XA 3A5MS 4Z94G 1Q8XA 1HQZ1 2XF1A 1NM1G 5HVKD 3CI5G 1WM4A 3CJBG 4BEX1 2FF3A 4CBUG 2LXXA 2I2QA 2L72A 3EG9A 4KEEA 3Q2BA 1D0NA 5FAFA 2VACA 5KYWB 1COFA 3CJCG 4LIZA 2VIKA 1NMDG 3A5LS 4CBWG 5KYXB 4JD2H 4PKHB 2FH2A 3EGXB 1YVNG 1T3YA 1UDMA 4KEDA 1M2VB 1M2OA 1KCQA 2MV2A 1PD0A 3DAWB 3EGDB 1M2VA 2MOTA 3L50A 1J72A 1AK6A 5L6WC 2D8BA 1M4JA 5IVUA 1H1VG 1RGIG 3EFOB 1CNUA 2MP4A 2FF6G
chains in the Genus database with same CATH superfamily
1NLVG 1TVJA 2LJ8A 1V6FA 2HD7A 2XFAA 1WFSA 1Q8GA 5A1MA 3EH1A 2FH4A 5KYXA 5KYWA 1F7SA 2NUTB 1VKKA 2NUTA 2FGHA 1P8XA 4PKIG 1NPHA 1CFYA 1AHQA 2VILA 3EFOA 1PD1A 4S10C 1P8ZG 1X67A 1SVQA 2LLFA 1T2LA 5KYUA 1AK7A 3DA7A 1QPVA 1JHWA 1C0GS 3CIPG 5KYYB 1PCXA 1MDUA 1WNJA 3EGDA 1SVYA 2NUPA 1SVRA 3EH2A 5FAEA 2KVKA 4CBXG 1ESVS 2NUPB 1DEJS 3FFKA 1T44G 3TU5B 5DD2A 2W0IA 3FG7A 3A5NS 5KYUB 3EGXA 1TMWA 2FH1A 1EQYS 1VFQA 3EG9B 4PKGG 3FG6A 5HVKB 5KYYA 1C0FS 3FFNA 3A5OS 1D4XG 2FH3A 4KEFA 5KYNA 1YAGG 2QTVA 1T3XA 3A5MS 4Z94G 1Q8XA 1HQZ1 2XF1A 1NM1G 5HVKD 3CI5G 1WM4A 3CJBG 4BEX1 2FF3A 4CBUG 2LXXA 2I2QA 2L72A 3EG9A 4KEEA 3Q2BA 1D0NA 5FAFA 2VACA 5KYWB 1COFA 3CJCG 4LIZA 2VIKA 1NMDG 3A5LS 4CBWG 5KYXB 4JD2H 4PKHB 2FH2A 3EGXB 1YVNG 1T3YA 1UDMA 4KEDA 1M2VB 1M2OA 1KCQA 2MV2A 1PD0A 3DAWB 3EGDB 1M2VA 2MOTA 3L50A 1J72A 1AK6A 5L6WC 2D8BA 1M4JA 5IVUA 1H1VG 1RGIG 3EFOB 1CNUA 2MP4A 2FF6G
chains in the Genus database with same CATH topology
1NLVG 1TVJA 2LJ8A 1V6FA 2HD7A 2XFAA 1WFSA 1Q8GA 5A1MA 3EH1A 2FH4A 5KYXA 5KYWA 1F7SA 2NUTB 1VKKA 2NUTA 2FGHA 1P8XA 4PKIG 1NPHA 1CFYA 1AHQA 2VILA 3EFOA 1PD1A 4S10C 1P8ZG 1X67A 1SVQA 2LLFA 1T2LA 5KYUA 1AK7A 3DA7A 1QPVA 1JHWA 1C0GS 3CIPG 5KYYB 1PCXA 1MDUA 1WNJA 3EGDA 1SVYA 2NUPA 1SVRA 3EH2A 5FAEA 2KVKA 4CBXG 1ESVS 2NUPB 1DEJS 3FFKA 1T44G 3TU5B 5DD2A 2W0IA 3FG7A 3A5NS 5KYUB 3EGXA 1TMWA 2FH1A 1EQYS 1VFQA 3EG9B 4PKGG 3FG6A 5HVKB 5KYYA 1C0FS 3FFNA 3A5OS 1D4XG 2FH3A 4KEFA 5KYNA 1YAGG 2QTVA 1T3XA 3A5MS 4Z94G 1Q8XA 1HQZ1 2XF1A 1NM1G 5HVKD 3CI5G 1WM4A 3CJBG 4BEX1 2FF3A 4CBUG 2LXXA 2I2QA 2L72A 3EG9A 4KEEA 3Q2BA 1D0NA 5FAFA 2VACA 5KYWB 1COFA 3CJCG 4LIZA 2VIKA 1NMDG 3A5LS 4CBWG 5KYXB 4JD2H 4PKHB 2FH2A 3EGXB 1YVNG 1T3YA 1UDMA 4KEDA 1M2VB 1M2OA 1KCQA 2MV2A 1PD0A 3DAWB 3EGDB 1M2VA 2MOTA 3L50A 1J72A 1AK6A 5L6WC 2D8BA 1M4JA 5IVUA 1H1VG 1RGIG 3EFOB 1CNUA 2MP4A 2FF6G
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1NLV G;  1TVJ A;  2LJ8 A;  1V6F A;  2HD7 A;  2XFA A;  1WFS A;  1Q8G A;  5A1M A;  3EH1 A;  2FH4 A;  5KYX A;  5KYW A;  1F7S A;  2NUT B;  1VKK A;  2NUT A;  2FGH A;  1P8X A;  4PKI G;  1NPH A;  1CFY A;  1AHQ A;  2VIL A;  3EFO A;  1PD1 A;  4S10 C;  1P8Z G;  1X67 A;  1SVQ A;  2LLF A;  1T2L A;  5KYU A;  1AK7 A;  1QPV A;  1JHW A;  1C0G S;  3CIP G;  5KYY B;  1PCX A;  1MDU A;  1WNJ A;  3EGD A;  1SVY A;  2NUP A;  1SVR A;  3EH2 A;  5FAE A;  2KVK A;  4CBX G;  1ESV S;  2NUP B;  1DEJ S;  3FFK A;  1T44 G;  3TU5 B;  5DD2 A;  2W0I A;  3FG7 A;  3A5N S;  5KYU B;  3EGX A;  1TMW A;  2FH1 A;  1EQY S;  1VFQ A;  3EG9 B;  4PKG G;  3FG6 A;  5HVK B;  5KYY A;  1C0F S;  3FFN A;  3A5O S;  1D4X G;  2FH3 A;  4KEF A;  5KYN A;  1YAG G;  2QTV A;  1T3X A;  3A5M S;  4Z94 G;  1Q8X A;  1HQZ 1;  2XF1 A;  1NM1 G;  5HVK D;  3CI5 G;  1WM4 A;  3CJB G;  4BEX 1;  2FF3 A;  4CBU G;  2LXX A;  2I2Q A;  2L72 A;  3EG9 A;  4KEE A;  3Q2B A;  1D0N A;  5FAF A;  2VAC A;  5KYW B;  1COF A;  3CJC G;  4LIZ A;  2VIK A;  1NMD G;  3A5L S;  4CBW G;  5KYX B;  4JD2 H;  4PKH B;  2FH2 A;  3EGX B;  1YVN G;  1T3Y A;  1UDM A;  4KED A;  1M2V B;  1M2O A;  1KCQ A;  2MV2 A;  1PD0 A;  3DAW B;  3EGD B;  1M2V A;  2MOT A;  3L50 A;  1J72 A;  1AK6 A;  5L6W C;  2D8B A;  1M4J A;  5IVU A;  1H1V G;  1RGI G;  3EFO B;  1CNU A;  2MP4 A;  2FF6 G; 
#chains in the Genus database with same CATH topology
 1NLV G;  1TVJ A;  2LJ8 A;  1V6F A;  2HD7 A;  2XFA A;  1WFS A;  1Q8G A;  5A1M A;  3EH1 A;  2FH4 A;  5KYX A;  5KYW A;  1F7S A;  2NUT B;  1VKK A;  2NUT A;  2FGH A;  1P8X A;  4PKI G;  1NPH A;  1CFY A;  1AHQ A;  2VIL A;  3EFO A;  1PD1 A;  4S10 C;  1P8Z G;  1X67 A;  1SVQ A;  2LLF A;  1T2L A;  5KYU A;  1AK7 A;  3DA7 A;  1QPV A;  1JHW A;  1C0G S;  3CIP G;  5KYY B;  1PCX A;  1MDU A;  1WNJ A;  3EGD A;  1SVY A;  2NUP A;  1SVR A;  3EH2 A;  5FAE A;  2KVK A;  4CBX G;  1ESV S;  2NUP B;  1DEJ S;  3FFK A;  1T44 G;  3TU5 B;  5DD2 A;  2W0I A;  3FG7 A;  3A5N S;  5KYU B;  3EGX A;  1TMW A;  2FH1 A;  1EQY S;  1VFQ A;  3EG9 B;  4PKG G;  3FG6 A;  5HVK B;  5KYY A;  1C0F S;  3FFN A;  3A5O S;  1D4X G;  2FH3 A;  4KEF A;  5KYN A;  1YAG G;  2QTV A;  1T3X A;  3A5M S;  4Z94 G;  1Q8X A;  1HQZ 1;  2XF1 A;  1NM1 G;  5HVK D;  3CI5 G;  1WM4 A;  3CJB G;  4BEX 1;  2FF3 A;  4CBU G;  2LXX A;  2I2Q A;  2L72 A;  3EG9 A;  4KEE A;  3Q2B A;  1D0N A;  5FAF A;  2VAC A;  5KYW B;  1COF A;  3CJC G;  4LIZ A;  2VIK A;  1NMD G;  3A5L S;  4CBW G;  5KYX B;  4JD2 H;  4PKH B;  2FH2 A;  3EGX B;  1YVN G;  1T3Y A;  1UDM A;  4KED A;  1M2V B;  1M2O A;  1KCQ A;  2MV2 A;  1PD0 A;  3DAW B;  3EGD B;  1M2V A;  2MOT A;  3L50 A;  1J72 A;  1AK6 A;  5L6W C;  2D8B A;  1M4J A;  5IVU A;  1H1V G;  1RGI G;  3EFO B;  1CNU A;  2MP4 A;  2FF6 G; 
#chains in the Genus database with same CATH homology
 1NLV G;  1TVJ A;  2LJ8 A;  1V6F A;  2HD7 A;  2XFA A;  1WFS A;  1Q8G A;  5A1M A;  3EH1 A;  2FH4 A;  5KYX A;  5KYW A;  1F7S A;  2NUT B;  1VKK A;  2NUT A;  2FGH A;  1P8X A;  4PKI G;  1NPH A;  1CFY A;  1AHQ A;  2VIL A;  3EFO A;  1PD1 A;  4S10 C;  1P8Z G;  1X67 A;  1SVQ A;  2LLF A;  1T2L A;  5KYU A;  1AK7 A;  3DA7 A;  1QPV A;  1JHW A;  1C0G S;  3CIP G;  5KYY B;  1PCX A;  1MDU A;  1WNJ A;  3EGD A;  1SVY A;  2NUP A;  1SVR A;  3EH2 A;  5FAE A;  2KVK A;  4CBX G;  1ESV S;  2NUP B;  1DEJ S;  3FFK A;  1T44 G;  3TU5 B;  5DD2 A;  2W0I A;  3FG7 A;  3A5N S;  5KYU B;  3EGX A;  1TMW A;  2FH1 A;  1EQY S;  1VFQ A;  3EG9 B;  4PKG G;  3FG6 A;  5HVK B;  5KYY A;  1C0F S;  3FFN A;  3A5O S;  1D4X G;  2FH3 A;  4KEF A;  5KYN A;  1YAG G;  2QTV A;  1T3X A;  3A5M S;  4Z94 G;  1Q8X A;  1HQZ 1;  2XF1 A;  1NM1 G;  5HVK D;  3CI5 G;  1WM4 A;  3CJB G;  4BEX 1;  2FF3 A;  4CBU G;  2LXX A;  2I2Q A;  2L72 A;  3EG9 A;  4KEE A;  3Q2B A;  1D0N A;  5FAF A;  2VAC A;  5KYW B;  1COF A;  3CJC G;  4LIZ A;  2VIK A;  1NMD G;  3A5L S;  4CBW G;  5KYX B;  4JD2 H;  4PKH B;  2FH2 A;  3EGX B;  1YVN G;  1T3Y A;  1UDM A;  4KED A;  1M2V B;  1M2O A;  1KCQ A;  2MV2 A;  1PD0 A;  3DAW B;  3EGD B;  1M2V A;  2MOT A;  3L50 A;  1J72 A;  1AK6 A;  5L6W C;  2D8B A;  1M4J A;  5IVU A;  1H1V G;  1RGI G;  3EFO B;  1CNU A;  2MP4 A;  2FF6 G; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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