1COFA

Yeast cofilin, orthorhombic crystal form
Total Genus 34
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
34
sequence length
135
structure length
135
Chain Sequence
VAVADESLTAFNDLKLGKKYKFILFGLNDAKTEIVVKETSTDPSYDAFLEKLPENDCLYAIYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSTDVQGTDFSEVSYDSVLERVSRGA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure determination of yeast cofilin.
pubmed doi rcsb
molecule tags Actin-binding protein
source organism Saccharomyces cerevisiae
molecule keywords COFILIN
total genus 34
structure length 135
sequence length 135
ec nomenclature
pdb deposition date 1996-11-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00241 Cofilin_ADF Cofilin/tropomyosin-type actin-binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 1cofA00
5FAFA 1SVYA 2NUTA 1WNJA 1NLVG 1P8XA 3EFOB 1PCXA 1VKKA 4PKIG 3TU5B 1WM4A 3EG9A 1TVJA 1D4XG 3CI5G 3A5MS 3FG7A 3FFNA 2VIKA 2VILA 1H1VG 1T44G 2D8BA 2LXXA 4PKHB 4BEX1 3CJCG 1AK6A 2FH2A 3EGXA 5KYWA 1M2VB 1AHQA 5DD2A 1COFA 3EGDB 4KEEA 1CNUA 2XFAA 5KYNA 1YAGG 4JD2H 4Z94G 1T2LA 5KYYB 1EQYS 1M4JA 1C0GS 1YVNG 1SVRA 2FF6G 2L72A 3FG6A 3FFKA 4S10C 5KYUB 1PD1A 1JHWA 1NMDG 2NUPA 2MOTA 2NUTB 4CBXG 3A5LS 1NM1G 3EG9B 4PKGG 2XF1A 5HVKB 1HQZ1 5L6WC 2MV2A 1ESVS 3CJBG 3DAWB 1RGIG 1SVQA 1CFYA 3EGDA 3EGXB 1C0FS 5KYXB 1X67A 5A1MA 1F7SA 1KCQA 4LIZA 5KYYA 1DEJS 5FAEA 2FH4A 2FH1A 3EFOA 1D0NA 1TMWA 2QTVA 1Q8XA 1VFQA 2FF3A 3EH1A 3A5NS 1T3XA 2LJ8A 1NPHA 2W0IA 3Q2BA 1Q8GA 1PD0A 4CBUG 1QPVA 1M2VA 4KEFA 1AK7A 2NUPB 1J72A 3CIPG 5KYWB 1WFSA 4CBWG 4KEDA 2FH3A 2HD7A 2LLFA 2VACA 5HVKD 1P8ZG 3EH2A 2I2QA 5IVUA 5KYXA 2KVKA 2FGHA 1MDUA 1V6FA 3L50A 2MP4A 1M2OA 3A5OS 1T3YA 5KYUA 1UDMA
chains in the Genus database with same CATH superfamily
5FAFA 1SVYA 2NUTA 1WNJA 1NLVG 1P8XA 3EFOB 3DA7A 1PCXA 1VKKA 4PKIG 3TU5B 1WM4A 3EG9A 1TVJA 1D4XG 3CI5G 3A5MS 3FG7A 3FFNA 2VIKA 2VILA 1H1VG 1T44G 2D8BA 2LXXA 4PKHB 4BEX1 3CJCG 1AK6A 2FH2A 3EGXA 5KYWA 1M2VB 1AHQA 5DD2A 1COFA 3EGDB 4KEEA 1CNUA 2XFAA 5KYNA 1YAGG 4JD2H 4Z94G 1T2LA 5KYYB 1EQYS 1M4JA 1C0GS 1YVNG 1SVRA 2FF6G 2L72A 3FG6A 3FFKA 4S10C 5KYUB 1PD1A 1JHWA 1NMDG 2NUPA 2MOTA 2NUTB 4CBXG 3A5LS 1NM1G 3EG9B 4PKGG 2XF1A 5HVKB 1HQZ1 5L6WC 2MV2A 1ESVS 3CJBG 3DAWB 1RGIG 1SVQA 1CFYA 3EGDA 3EGXB 1C0FS 5KYXB 1X67A 5A1MA 1F7SA 1KCQA 4LIZA 5KYYA 1DEJS 5FAEA 2FH4A 2FH1A 3EFOA 1D0NA 1TMWA 2QTVA 1Q8XA 1VFQA 2FF3A 3EH1A 3A5NS 1T3XA 2LJ8A 1NPHA 2W0IA 3Q2BA 1Q8GA 1PD0A 4CBUG 1QPVA 1M2VA 4KEFA 1AK7A 2NUPB 1J72A 3CIPG 5KYWB 1WFSA 4CBWG 4KEDA 2FH3A 2HD7A 2LLFA 2VACA 5HVKD 1P8ZG 3EH2A 2I2QA 5IVUA 5KYXA 2KVKA 2FGHA 1MDUA 1V6FA 3L50A 2MP4A 1M2OA 3A5OS 1T3YA 5KYUA 1UDMA
chains in the Genus database with same CATH topology
5FAFA 1SVYA 2NUTA 1WNJA 1NLVG 1P8XA 3EFOB 3DA7A 1PCXA 1VKKA 4PKIG 3TU5B 1WM4A 3EG9A 1TVJA 1D4XG 3CI5G 3A5MS 3FG7A 3FFNA 2VIKA 2VILA 1H1VG 1T44G 2D8BA 2LXXA 4PKHB 4BEX1 3CJCG 1AK6A 2FH2A 3EGXA 5KYWA 1M2VB 1AHQA 5DD2A 1COFA 3EGDB 4KEEA 1CNUA 2XFAA 5KYNA 1YAGG 4JD2H 4Z94G 1T2LA 5KYYB 1EQYS 1M4JA 1C0GS 1YVNG 1SVRA 2FF6G 2L72A 3FG6A 3FFKA 4S10C 5KYUB 1PD1A 1JHWA 1NMDG 2NUPA 2MOTA 2NUTB 4CBXG 3A5LS 1NM1G 3EG9B 4PKGG 2XF1A 5HVKB 1HQZ1 5L6WC 2MV2A 1ESVS 3CJBG 3DAWB 1RGIG 1SVQA 1CFYA 3EGDA 3EGXB 1C0FS 5KYXB 1X67A 5A1MA 1F7SA 1KCQA 4LIZA 5KYYA 1DEJS 5FAEA 2FH4A 2FH1A 3EFOA 1D0NA 1TMWA 2QTVA 1Q8XA 1VFQA 2FF3A 3EH1A 3A5NS 1T3XA 2LJ8A 1NPHA 2W0IA 3Q2BA 1Q8GA 1PD0A 4CBUG 1QPVA 1M2VA 4KEFA 1AK7A 2NUPB 1J72A 3CIPG 5KYWB 1WFSA 4CBWG 4KEDA 2FH3A 2HD7A 2LLFA 2VACA 5HVKD 1P8ZG 3EH2A 2I2QA 5IVUA 5KYXA 2KVKA 2FGHA 1MDUA 1V6FA 3L50A 2MP4A 1M2OA 3A5OS 1T3YA 5KYUA 1UDMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5FAF A;  1SVY A;  2NUT A;  1WNJ A;  1NLV G;  1P8X A;  3EFO B;  1PCX A;  1VKK A;  4PKI G;  3TU5 B;  1WM4 A;  3EG9 A;  1TVJ A;  1D4X G;  3CI5 G;  3A5M S;  3FG7 A;  3FFN A;  2VIK A;  2VIL A;  1H1V G;  1T44 G;  2D8B A;  2LXX A;  4PKH B;  4BEX 1;  3CJC G;  1AK6 A;  2FH2 A;  3EGX A;  5KYW A;  1M2V B;  1AHQ A;  5DD2 A;  1COF A;  3EGD B;  4KEE A;  1CNU A;  2XFA A;  5KYN A;  1YAG G;  4JD2 H;  4Z94 G;  1T2L A;  5KYY B;  1EQY S;  1M4J A;  1C0G S;  1YVN G;  1SVR A;  2FF6 G;  2L72 A;  3FG6 A;  3FFK A;  4S10 C;  5KYU B;  1PD1 A;  1JHW A;  1NMD G;  2NUP A;  2MOT A;  2NUT B;  4CBX G;  3A5L S;  1NM1 G;  3EG9 B;  4PKG G;  2XF1 A;  5HVK B;  1HQZ 1;  5L6W C;  2MV2 A;  1ESV S;  3CJB G;  3DAW B;  1RGI G;  1SVQ A;  1CFY A;  3EGD A;  3EGX B;  1C0F S;  5KYX B;  1X67 A;  5A1M A;  1F7S A;  1KCQ A;  4LIZ A;  5KYY A;  1DEJ S;  5FAE A;  2FH4 A;  2FH1 A;  3EFO A;  1D0N A;  1TMW A;  2QTV A;  1Q8X A;  1VFQ A;  2FF3 A;  3EH1 A;  3A5N S;  1T3X A;  2LJ8 A;  1NPH A;  2W0I A;  3Q2B A;  1Q8G A;  1PD0 A;  4CBU G;  1QPV A;  1M2V A;  4KEF A;  1AK7 A;  2NUP B;  1J72 A;  3CIP G;  5KYW B;  1WFS A;  4CBW G;  4KED A;  2FH3 A;  2HD7 A;  2LLF A;  2VAC A;  5HVK D;  1P8Z G;  3EH2 A;  2I2Q A;  5IVU A;  5KYX A;  2KVK A;  2FGH A;  1MDU A;  1V6F A;  3L50 A;  2MP4 A;  1M2O A;  3A5O S;  1T3Y A;  5KYU A;  1UDM A; 
#chains in the Genus database with same CATH topology
 5FAF A;  1SVY A;  2NUT A;  1WNJ A;  1NLV G;  1P8X A;  3EFO B;  3DA7 A;  1PCX A;  1VKK A;  4PKI G;  3TU5 B;  1WM4 A;  3EG9 A;  1TVJ A;  1D4X G;  3CI5 G;  3A5M S;  3FG7 A;  3FFN A;  2VIK A;  2VIL A;  1H1V G;  1T44 G;  2D8B A;  2LXX A;  4PKH B;  4BEX 1;  3CJC G;  1AK6 A;  2FH2 A;  3EGX A;  5KYW A;  1M2V B;  1AHQ A;  5DD2 A;  1COF A;  3EGD B;  4KEE A;  1CNU A;  2XFA A;  5KYN A;  1YAG G;  4JD2 H;  4Z94 G;  1T2L A;  5KYY B;  1EQY S;  1M4J A;  1C0G S;  1YVN G;  1SVR A;  2FF6 G;  2L72 A;  3FG6 A;  3FFK A;  4S10 C;  5KYU B;  1PD1 A;  1JHW A;  1NMD G;  2NUP A;  2MOT A;  2NUT B;  4CBX G;  3A5L S;  1NM1 G;  3EG9 B;  4PKG G;  2XF1 A;  5HVK B;  1HQZ 1;  5L6W C;  2MV2 A;  1ESV S;  3CJB G;  3DAW B;  1RGI G;  1SVQ A;  1CFY A;  3EGD A;  3EGX B;  1C0F S;  5KYX B;  1X67 A;  5A1M A;  1F7S A;  1KCQ A;  4LIZ A;  5KYY A;  1DEJ S;  5FAE A;  2FH4 A;  2FH1 A;  3EFO A;  1D0N A;  1TMW A;  2QTV A;  1Q8X A;  1VFQ A;  2FF3 A;  3EH1 A;  3A5N S;  1T3X A;  2LJ8 A;  1NPH A;  2W0I A;  3Q2B A;  1Q8G A;  1PD0 A;  4CBU G;  1QPV A;  1M2V A;  4KEF A;  1AK7 A;  2NUP B;  1J72 A;  3CIP G;  5KYW B;  1WFS A;  4CBW G;  4KED A;  2FH3 A;  2HD7 A;  2LLF A;  2VAC A;  5HVK D;  1P8Z G;  3EH2 A;  2I2Q A;  5IVU A;  5KYX A;  2KVK A;  2FGH A;  1MDU A;  1V6F A;  3L50 A;  2MP4 A;  1M2O A;  3A5O S;  1T3Y A;  5KYU A;  1UDM A; 
#chains in the Genus database with same CATH homology
 5FAF A;  1SVY A;  2NUT A;  1WNJ A;  1NLV G;  1P8X A;  3EFO B;  3DA7 A;  1PCX A;  1VKK A;  4PKI G;  3TU5 B;  1WM4 A;  3EG9 A;  1TVJ A;  1D4X G;  3CI5 G;  3A5M S;  3FG7 A;  3FFN A;  2VIK A;  2VIL A;  1H1V G;  1T44 G;  2D8B A;  2LXX A;  4PKH B;  4BEX 1;  3CJC G;  1AK6 A;  2FH2 A;  3EGX A;  5KYW A;  1M2V B;  1AHQ A;  5DD2 A;  1COF A;  3EGD B;  4KEE A;  1CNU A;  2XFA A;  5KYN A;  1YAG G;  4JD2 H;  4Z94 G;  1T2L A;  5KYY B;  1EQY S;  1M4J A;  1C0G S;  1YVN G;  1SVR A;  2FF6 G;  2L72 A;  3FG6 A;  3FFK A;  4S10 C;  5KYU B;  1PD1 A;  1JHW A;  1NMD G;  2NUP A;  2MOT A;  2NUT B;  4CBX G;  3A5L S;  1NM1 G;  3EG9 B;  4PKG G;  2XF1 A;  5HVK B;  1HQZ 1;  5L6W C;  2MV2 A;  1ESV S;  3CJB G;  3DAW B;  1RGI G;  1SVQ A;  1CFY A;  3EGD A;  3EGX B;  1C0F S;  5KYX B;  1X67 A;  5A1M A;  1F7S A;  1KCQ A;  4LIZ A;  5KYY A;  1DEJ S;  5FAE A;  2FH4 A;  2FH1 A;  3EFO A;  1D0N A;  1TMW A;  2QTV A;  1Q8X A;  1VFQ A;  2FF3 A;  3EH1 A;  3A5N S;  1T3X A;  2LJ8 A;  1NPH A;  2W0I A;  3Q2B A;  1Q8G A;  1PD0 A;  4CBU G;  1QPV A;  1M2V A;  4KEF A;  1AK7 A;  2NUP B;  1J72 A;  3CIP G;  5KYW B;  1WFS A;  4CBW G;  4KED A;  2FH3 A;  2HD7 A;  2LLF A;  2VAC A;  5HVK D;  1P8Z G;  3EH2 A;  2I2Q A;  5IVU A;  5KYX A;  2KVK A;  2FGH A;  1MDU A;  1V6F A;  3L50 A;  2MP4 A;  1M2O A;  3A5O S;  1T3Y A;  5KYU A;  1UDM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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