1COFA

Yeast cofilin, orthorhombic crystal form
Total Genus 34
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
34
sequence length
135
structure length
135
Chain Sequence
VAVADESLTAFNDLKLGKKYKFILFGLNDAKTEIVVKETSTDPSYDAFLEKLPENDCLYAIYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSTDVQGTDFSEVSYDSVLERVSRGA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structure determination of yeast cofilin.
pubmed doi rcsb
molecule tags Actin-binding protein
source organism Saccharomyces cerevisiae
molecule keywords COFILIN
total genus 34
structure length 135
sequence length 135
ec nomenclature
pdb deposition date 1996-11-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00241 Cofilin_ADF Cofilin/tropomyosin-type actin-binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 1cofA00
2FGHA 1P8XA 1WNJA 1Q8XA 5A1MA 4CBUG 1T3YA 4KEEA 5HVKD 1D0NA 3EGXA 2QTVA 1AHQA 1JHWA 4KEFA 1M2OA 2FF3A 3EG9B 5HVKB 5KYYA 1NM1G 3TU5B 2FH2A 2XFAA 3EGXB 4JD2H 1YAGG 3EFOA 3A5NS 1NMDG 2MOTA 1TVJA 2D8BA 1V6FA 5DD2A 2NUTA 2LLFA 1NPHA 4LIZA 3FG6A 3FFNA 2FH3A 1UDMA 3EFOB 1PCXA 3EGDA 1SVQA 5KYXA 1VKKA 4Z94G 1PD1A 1C0FS 3Q2BA 1NLVG 3EGDB 1SVRA 1T2LA 5FAFA 2NUPA 3EH2A 1ESVS 1T3XA 5KYUA 3A5OS 1QPVA 4KEDA 3FG7A 5IVUA 1VFQA 1F7SA 4CBXG 2NUPB 2KVKA 5KYYB 1HQZ1 2LJ8A 5KYUB 1COFA 1Q8GA 3CJBG 2FF6G 2NUTB 1WM4A 1C0GS 1KCQA 1X67A 1M2VA 2VIKA 4S10C 1H1VG 2MP4A 1M4JA 4PKHB 1T44G 2VILA 1CFYA 2VACA 1RGIG 3CI5G 2HD7A 1D4XG 5KYXB 1SVYA 1EQYS 1CNUA 3CIPG 3A5LS 2FH4A 4BEX1 2XF1A 1AK6A 1DEJS 1MDUA 5KYWA 5L6WC 2W0IA 3EG9A 5KYWB 1YVNG 5FAEA 1PD0A 3CJCG 3DAWB 2MV2A 4PKGG 2LXXA 1P8ZG 1WFSA 3L50A 2FH1A 5KYNA 1M2VB 3EH1A 4PKIG 3A5MS 3FFKA 1TMWA 4CBWG 1AK7A 2I2QA 1J72A 2L72A
chains in the Genus database with same CATH superfamily
2FGHA 1P8XA 1WNJA 1Q8XA 5A1MA 4CBUG 1T3YA 4KEEA 5HVKD 1D0NA 3EGXA 2QTVA 1AHQA 1JHWA 4KEFA 1M2OA 2FF3A 3EG9B 5HVKB 5KYYA 1NM1G 3TU5B 2FH2A 2XFAA 3EGXB 4JD2H 1YAGG 3EFOA 3A5NS 1NMDG 2MOTA 1TVJA 2D8BA 1V6FA 5DD2A 2NUTA 2LLFA 1NPHA 4LIZA 3FG6A 3FFNA 2FH3A 1UDMA 3EFOB 1PCXA 3EGDA 1SVQA 5KYXA 1VKKA 4Z94G 1PD1A 1C0FS 3Q2BA 1NLVG 3EGDB 1SVRA 1T2LA 5FAFA 2NUPA 3EH2A 1ESVS 1T3XA 5KYUA 3A5OS 1QPVA 4KEDA 3FG7A 5IVUA 1VFQA 1F7SA 4CBXG 2NUPB 2KVKA 5KYYB 3DA7A 1HQZ1 2LJ8A 5KYUB 1COFA 1Q8GA 3CJBG 2FF6G 2NUTB 1WM4A 1C0GS 1KCQA 1X67A 1M2VA 2VIKA 4S10C 1H1VG 2MP4A 1M4JA 4PKHB 1T44G 2VILA 1CFYA 2VACA 1RGIG 3CI5G 2HD7A 1D4XG 5KYXB 1SVYA 1EQYS 1CNUA 3CIPG 3A5LS 2FH4A 4BEX1 2XF1A 1AK6A 1DEJS 1MDUA 5KYWA 5L6WC 2W0IA 3EG9A 5KYWB 1YVNG 5FAEA 1PD0A 3CJCG 3DAWB 2MV2A 4PKGG 2LXXA 1P8ZG 1WFSA 3L50A 2FH1A 5KYNA 1M2VB 3EH1A 4PKIG 3A5MS 3FFKA 1TMWA 4CBWG 1AK7A 2I2QA 1J72A 2L72A
chains in the Genus database with same CATH topology
2FGHA 1P8XA 1WNJA 1Q8XA 5A1MA 4CBUG 1T3YA 4KEEA 5HVKD 1D0NA 3EGXA 2QTVA 1AHQA 1JHWA 4KEFA 1M2OA 2FF3A 3EG9B 5HVKB 5KYYA 1NM1G 3TU5B 2FH2A 2XFAA 3EGXB 4JD2H 1YAGG 3EFOA 3A5NS 1NMDG 2MOTA 1TVJA 2D8BA 1V6FA 5DD2A 2NUTA 2LLFA 1NPHA 4LIZA 3FG6A 3FFNA 2FH3A 1UDMA 3EFOB 1PCXA 3EGDA 1SVQA 5KYXA 1VKKA 4Z94G 1PD1A 1C0FS 3Q2BA 1NLVG 3EGDB 1SVRA 1T2LA 5FAFA 2NUPA 3EH2A 1ESVS 1T3XA 5KYUA 3A5OS 1QPVA 4KEDA 3FG7A 5IVUA 1VFQA 1F7SA 4CBXG 2NUPB 2KVKA 5KYYB 3DA7A 1HQZ1 2LJ8A 5KYUB 1COFA 1Q8GA 3CJBG 2FF6G 2NUTB 1WM4A 1C0GS 1KCQA 1X67A 1M2VA 2VIKA 4S10C 1H1VG 2MP4A 1M4JA 4PKHB 1T44G 2VILA 1CFYA 2VACA 1RGIG 3CI5G 2HD7A 1D4XG 5KYXB 1SVYA 1EQYS 1CNUA 3CIPG 3A5LS 2FH4A 4BEX1 2XF1A 1AK6A 1DEJS 1MDUA 5KYWA 5L6WC 2W0IA 3EG9A 5KYWB 1YVNG 5FAEA 1PD0A 3CJCG 3DAWB 2MV2A 4PKGG 2LXXA 1P8ZG 1WFSA 3L50A 2FH1A 5KYNA 1M2VB 3EH1A 4PKIG 3A5MS 3FFKA 1TMWA 4CBWG 1AK7A 2I2QA 1J72A 2L72A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2FGH A;  1P8X A;  1WNJ A;  1Q8X A;  5A1M A;  4CBU G;  1T3Y A;  4KEE A;  5HVK D;  1D0N A;  3EGX A;  2QTV A;  1AHQ A;  1JHW A;  4KEF A;  1M2O A;  2FF3 A;  3EG9 B;  5HVK B;  5KYY A;  1NM1 G;  3TU5 B;  2FH2 A;  2XFA A;  3EGX B;  4JD2 H;  1YAG G;  3EFO A;  3A5N S;  1NMD G;  2MOT A;  1TVJ A;  2D8B A;  1V6F A;  5DD2 A;  2NUT A;  2LLF A;  1NPH A;  4LIZ A;  3FG6 A;  3FFN A;  2FH3 A;  1UDM A;  3EFO B;  1PCX A;  3EGD A;  1SVQ A;  5KYX A;  1VKK A;  4Z94 G;  1PD1 A;  1C0F S;  3Q2B A;  1NLV G;  3EGD B;  1SVR A;  1T2L A;  5FAF A;  2NUP A;  3EH2 A;  1ESV S;  1T3X A;  5KYU A;  3A5O S;  1QPV A;  4KED A;  3FG7 A;  5IVU A;  1VFQ A;  1F7S A;  4CBX G;  2NUP B;  2KVK A;  5KYY B;  1HQZ 1;  2LJ8 A;  5KYU B;  1COF A;  1Q8G A;  3CJB G;  2FF6 G;  2NUT B;  1WM4 A;  1C0G S;  1KCQ A;  1X67 A;  1M2V A;  2VIK A;  4S10 C;  1H1V G;  2MP4 A;  1M4J A;  4PKH B;  1T44 G;  2VIL A;  1CFY A;  2VAC A;  1RGI G;  3CI5 G;  2HD7 A;  1D4X G;  5KYX B;  1SVY A;  1EQY S;  1CNU A;  3CIP G;  3A5L S;  2FH4 A;  4BEX 1;  2XF1 A;  1AK6 A;  1DEJ S;  1MDU A;  5KYW A;  5L6W C;  2W0I A;  3EG9 A;  5KYW B;  1YVN G;  5FAE A;  1PD0 A;  3CJC G;  3DAW B;  2MV2 A;  4PKG G;  2LXX A;  1P8Z G;  1WFS A;  3L50 A;  2FH1 A;  5KYN A;  1M2V B;  3EH1 A;  4PKI G;  3A5M S;  3FFK A;  1TMW A;  4CBW G;  1AK7 A;  2I2Q A;  1J72 A;  2L72 A; 
#chains in the Genus database with same CATH topology
 2FGH A;  1P8X A;  1WNJ A;  1Q8X A;  5A1M A;  4CBU G;  1T3Y A;  4KEE A;  5HVK D;  1D0N A;  3EGX A;  2QTV A;  1AHQ A;  1JHW A;  4KEF A;  1M2O A;  2FF3 A;  3EG9 B;  5HVK B;  5KYY A;  1NM1 G;  3TU5 B;  2FH2 A;  2XFA A;  3EGX B;  4JD2 H;  1YAG G;  3EFO A;  3A5N S;  1NMD G;  2MOT A;  1TVJ A;  2D8B A;  1V6F A;  5DD2 A;  2NUT A;  2LLF A;  1NPH A;  4LIZ A;  3FG6 A;  3FFN A;  2FH3 A;  1UDM A;  3EFO B;  1PCX A;  3EGD A;  1SVQ A;  5KYX A;  1VKK A;  4Z94 G;  1PD1 A;  1C0F S;  3Q2B A;  1NLV G;  3EGD B;  1SVR A;  1T2L A;  5FAF A;  2NUP A;  3EH2 A;  1ESV S;  1T3X A;  5KYU A;  3A5O S;  1QPV A;  4KED A;  3FG7 A;  5IVU A;  1VFQ A;  1F7S A;  4CBX G;  2NUP B;  2KVK A;  5KYY B;  3DA7 A;  1HQZ 1;  2LJ8 A;  5KYU B;  1COF A;  1Q8G A;  3CJB G;  2FF6 G;  2NUT B;  1WM4 A;  1C0G S;  1KCQ A;  1X67 A;  1M2V A;  2VIK A;  4S10 C;  1H1V G;  2MP4 A;  1M4J A;  4PKH B;  1T44 G;  2VIL A;  1CFY A;  2VAC A;  1RGI G;  3CI5 G;  2HD7 A;  1D4X G;  5KYX B;  1SVY A;  1EQY S;  1CNU A;  3CIP G;  3A5L S;  2FH4 A;  4BEX 1;  2XF1 A;  1AK6 A;  1DEJ S;  1MDU A;  5KYW A;  5L6W C;  2W0I A;  3EG9 A;  5KYW B;  1YVN G;  5FAE A;  1PD0 A;  3CJC G;  3DAW B;  2MV2 A;  4PKG G;  2LXX A;  1P8Z G;  1WFS A;  3L50 A;  2FH1 A;  5KYN A;  1M2V B;  3EH1 A;  4PKI G;  3A5M S;  3FFK A;  1TMW A;  4CBW G;  1AK7 A;  2I2Q A;  1J72 A;  2L72 A; 
#chains in the Genus database with same CATH homology
 2FGH A;  1P8X A;  1WNJ A;  1Q8X A;  5A1M A;  4CBU G;  1T3Y A;  4KEE A;  5HVK D;  1D0N A;  3EGX A;  2QTV A;  1AHQ A;  1JHW A;  4KEF A;  1M2O A;  2FF3 A;  3EG9 B;  5HVK B;  5KYY A;  1NM1 G;  3TU5 B;  2FH2 A;  2XFA A;  3EGX B;  4JD2 H;  1YAG G;  3EFO A;  3A5N S;  1NMD G;  2MOT A;  1TVJ A;  2D8B A;  1V6F A;  5DD2 A;  2NUT A;  2LLF A;  1NPH A;  4LIZ A;  3FG6 A;  3FFN A;  2FH3 A;  1UDM A;  3EFO B;  1PCX A;  3EGD A;  1SVQ A;  5KYX A;  1VKK A;  4Z94 G;  1PD1 A;  1C0F S;  3Q2B A;  1NLV G;  3EGD B;  1SVR A;  1T2L A;  5FAF A;  2NUP A;  3EH2 A;  1ESV S;  1T3X A;  5KYU A;  3A5O S;  1QPV A;  4KED A;  3FG7 A;  5IVU A;  1VFQ A;  1F7S A;  4CBX G;  2NUP B;  2KVK A;  5KYY B;  3DA7 A;  1HQZ 1;  2LJ8 A;  5KYU B;  1COF A;  1Q8G A;  3CJB G;  2FF6 G;  2NUT B;  1WM4 A;  1C0G S;  1KCQ A;  1X67 A;  1M2V A;  2VIK A;  4S10 C;  1H1V G;  2MP4 A;  1M4J A;  4PKH B;  1T44 G;  2VIL A;  1CFY A;  2VAC A;  1RGI G;  3CI5 G;  2HD7 A;  1D4X G;  5KYX B;  1SVY A;  1EQY S;  1CNU A;  3CIP G;  3A5L S;  2FH4 A;  4BEX 1;  2XF1 A;  1AK6 A;  1DEJ S;  1MDU A;  5KYW A;  5L6W C;  2W0I A;  3EG9 A;  5KYW B;  1YVN G;  5FAE A;  1PD0 A;  3CJC G;  3DAW B;  2MV2 A;  4PKG G;  2LXX A;  1P8Z G;  1WFS A;  3L50 A;  2FH1 A;  5KYN A;  1M2V B;  3EH1 A;  4PKI G;  3A5M S;  3FFK A;  1TMW A;  4CBW G;  1AK7 A;  2I2Q A;  1J72 A;  2L72 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...