1COFA

Yeast cofilin, orthorhombic crystal form
Total Genus 34
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
34
sequence length
135
structure length
135
Chain Sequence
VAVADESLTAFNDLKLGKKYKFILFGLNDAKTEIVVKETSTDPSYDAFLEKLPENDCLYAIYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSTDVQGTDFSEVSYDSVLERVSRGA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structure determination of yeast cofilin.
pubmed doi rcsb
molecule tags Actin-binding protein
source organism Saccharomyces cerevisiae
molecule keywords COFILIN
total genus 34
structure length 135
sequence length 135
ec nomenclature
pdb deposition date 1996-11-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00241 Cofilin_ADF Cofilin/tropomyosin-type actin-binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 1cofA00
4CBXG 5KYUB 3FG7A 1TMWA 3L50A 2FF3A 5KYWB 5KYWA 3EG9A 2I2QA 1F7SA 2XFAA 1V6FA 4S10C 1M4JA 3EFOA 1D4XG 2D8BA 3FG6A 5FAEA 1AHQA 5DD2A 1T2LA 4KEFA 1SVQA 1SVRA 4LIZA 3Q2BA 2KVKA 1VFQA 2FGHA 3DAWB 2LJ8A 3EH1A 3EH2A 1M2VB 3EGXA 1M2VA 5IVUA 4PKIG 1DEJS 1Q8XA 3EG9B 1PD0A 1WNJA 2LLFA 5HVKD 4PKGG 1YVNG 1COFA 2W0IA 3EFOB 1KCQA 5HVKB 3FFNA 1PCXA 4KEDA 1ESVS 1AK6A 1WFSA 4PKHB 1T3YA 1UDMA 1YAGG 2MP4A 1WM4A 4KEEA 3A5NS 3CI5G 2MV2A 2VACA 3EGXB 3CIPG 2VIKA 1AK7A 1EQYS 2MOTA 1RGIG 2FF6G 1H1VG 1SVYA 2FH4A 5KYNA 4CBUG 5L6WC 1Q8GA 2QTVA 2L72A 2FH1A 3A5LS 4Z94G 5KYYB 5KYYA 5FAFA 3A5OS 4CBWG 2FH3A 1NPHA 1HQZ1 1CNUA 1C0GS 2FH2A 2HD7A 2VILA 3FFKA 1MDUA 3CJCG 3TU5B 1P8ZG 1NMDG 1CFYA 1PD1A 1JHWA 1T44G 1M2OA 4JD2H 1J72A 5KYXB 5KYXA 1X67A 1C0FS 1D0NA 3CJBG 1NM1G 1NLVG 2XF1A 1TVJA 1P8XA 3EGDB 3EGDA 3A5MS 2NUTB 2NUTA 5A1MA 2LXXA 1VKKA 2NUPB 1QPVA 2NUPA 1T3XA 4BEX1 5KYUA
chains in the Genus database with same CATH superfamily
4CBXG 5KYUB 3FG7A 1TMWA 3L50A 2FF3A 3DA7A 5KYWB 5KYWA 3EG9A 2I2QA 1F7SA 2XFAA 1V6FA 4S10C 1M4JA 3EFOA 1D4XG 2D8BA 3FG6A 5FAEA 1AHQA 5DD2A 1T2LA 4KEFA 1SVQA 1SVRA 4LIZA 3Q2BA 2KVKA 1VFQA 2FGHA 3DAWB 2LJ8A 3EH1A 3EH2A 1M2VB 3EGXA 1M2VA 5IVUA 4PKIG 1DEJS 1Q8XA 3EG9B 1PD0A 1WNJA 2LLFA 5HVKD 4PKGG 1YVNG 1COFA 2W0IA 3EFOB 1KCQA 5HVKB 3FFNA 1PCXA 4KEDA 1ESVS 1AK6A 1WFSA 4PKHB 1T3YA 1UDMA 1YAGG 2MP4A 1WM4A 4KEEA 3A5NS 3CI5G 2MV2A 2VACA 3EGXB 3CIPG 2VIKA 1AK7A 1EQYS 2MOTA 1RGIG 2FF6G 1H1VG 1SVYA 2FH4A 5KYNA 4CBUG 5L6WC 1Q8GA 2QTVA 2L72A 2FH1A 3A5LS 4Z94G 5KYYB 5KYYA 5FAFA 3A5OS 4CBWG 2FH3A 1NPHA 1HQZ1 1CNUA 1C0GS 2FH2A 2HD7A 2VILA 3FFKA 1MDUA 3CJCG 3TU5B 1P8ZG 1NMDG 1CFYA 1PD1A 1JHWA 1T44G 1M2OA 4JD2H 1J72A 5KYXB 5KYXA 1X67A 1C0FS 1D0NA 3CJBG 1NM1G 1NLVG 2XF1A 1TVJA 1P8XA 3EGDB 3EGDA 3A5MS 2NUTB 2NUTA 5A1MA 2LXXA 1VKKA 2NUPB 1QPVA 2NUPA 1T3XA 4BEX1 5KYUA
chains in the Genus database with same CATH topology
4CBXG 5KYUB 3FG7A 1TMWA 3L50A 2FF3A 3DA7A 5KYWB 5KYWA 3EG9A 2I2QA 1F7SA 2XFAA 1V6FA 4S10C 1M4JA 3EFOA 1D4XG 2D8BA 3FG6A 5FAEA 1AHQA 5DD2A 1T2LA 4KEFA 1SVQA 1SVRA 4LIZA 3Q2BA 2KVKA 1VFQA 2FGHA 3DAWB 2LJ8A 3EH1A 3EH2A 1M2VB 3EGXA 1M2VA 5IVUA 4PKIG 1DEJS 1Q8XA 3EG9B 1PD0A 1WNJA 2LLFA 5HVKD 4PKGG 1YVNG 1COFA 2W0IA 3EFOB 1KCQA 5HVKB 3FFNA 1PCXA 4KEDA 1ESVS 1AK6A 1WFSA 4PKHB 1T3YA 1UDMA 1YAGG 2MP4A 1WM4A 4KEEA 3A5NS 3CI5G 2MV2A 2VACA 3EGXB 3CIPG 2VIKA 1AK7A 1EQYS 2MOTA 1RGIG 2FF6G 1H1VG 1SVYA 2FH4A 5KYNA 4CBUG 5L6WC 1Q8GA 2QTVA 2L72A 2FH1A 3A5LS 4Z94G 5KYYB 5KYYA 5FAFA 3A5OS 4CBWG 2FH3A 1NPHA 1HQZ1 1CNUA 1C0GS 2FH2A 2HD7A 2VILA 3FFKA 1MDUA 3CJCG 3TU5B 1P8ZG 1NMDG 1CFYA 1PD1A 1JHWA 1T44G 1M2OA 4JD2H 1J72A 5KYXB 5KYXA 1X67A 1C0FS 1D0NA 3CJBG 1NM1G 1NLVG 2XF1A 1TVJA 1P8XA 3EGDB 3EGDA 3A5MS 2NUTB 2NUTA 5A1MA 2LXXA 1VKKA 2NUPB 1QPVA 2NUPA 1T3XA 4BEX1 5KYUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4CBX G;  5KYU B;  3FG7 A;  1TMW A;  3L50 A;  2FF3 A;  5KYW B;  5KYW A;  3EG9 A;  2I2Q A;  1F7S A;  2XFA A;  1V6F A;  4S10 C;  1M4J A;  3EFO A;  1D4X G;  2D8B A;  3FG6 A;  5FAE A;  1AHQ A;  5DD2 A;  1T2L A;  4KEF A;  1SVQ A;  1SVR A;  4LIZ A;  3Q2B A;  2KVK A;  1VFQ A;  2FGH A;  3DAW B;  2LJ8 A;  3EH1 A;  3EH2 A;  1M2V B;  3EGX A;  1M2V A;  5IVU A;  4PKI G;  1DEJ S;  1Q8X A;  3EG9 B;  1PD0 A;  1WNJ A;  2LLF A;  5HVK D;  4PKG G;  1YVN G;  1COF A;  2W0I A;  3EFO B;  1KCQ A;  5HVK B;  3FFN A;  1PCX A;  4KED A;  1ESV S;  1AK6 A;  1WFS A;  4PKH B;  1T3Y A;  1UDM A;  1YAG G;  2MP4 A;  1WM4 A;  4KEE A;  3A5N S;  3CI5 G;  2MV2 A;  2VAC A;  3EGX B;  3CIP G;  2VIK A;  1AK7 A;  1EQY S;  2MOT A;  1RGI G;  2FF6 G;  1H1V G;  1SVY A;  2FH4 A;  5KYN A;  4CBU G;  5L6W C;  1Q8G A;  2QTV A;  2L72 A;  2FH1 A;  3A5L S;  4Z94 G;  5KYY B;  5KYY A;  5FAF A;  3A5O S;  4CBW G;  2FH3 A;  1NPH A;  1HQZ 1;  1CNU A;  1C0G S;  2FH2 A;  2HD7 A;  2VIL A;  3FFK A;  1MDU A;  3CJC G;  3TU5 B;  1P8Z G;  1NMD G;  1CFY A;  1PD1 A;  1JHW A;  1T44 G;  1M2O A;  4JD2 H;  1J72 A;  5KYX B;  5KYX A;  1X67 A;  1C0F S;  1D0N A;  3CJB G;  1NM1 G;  1NLV G;  2XF1 A;  1TVJ A;  1P8X A;  3EGD B;  3EGD A;  3A5M S;  2NUT B;  2NUT A;  5A1M A;  2LXX A;  1VKK A;  2NUP B;  1QPV A;  2NUP A;  1T3X A;  4BEX 1;  5KYU A; 
#chains in the Genus database with same CATH topology
 4CBX G;  5KYU B;  3FG7 A;  1TMW A;  3L50 A;  2FF3 A;  3DA7 A;  5KYW B;  5KYW A;  3EG9 A;  2I2Q A;  1F7S A;  2XFA A;  1V6F A;  4S10 C;  1M4J A;  3EFO A;  1D4X G;  2D8B A;  3FG6 A;  5FAE A;  1AHQ A;  5DD2 A;  1T2L A;  4KEF A;  1SVQ A;  1SVR A;  4LIZ A;  3Q2B A;  2KVK A;  1VFQ A;  2FGH A;  3DAW B;  2LJ8 A;  3EH1 A;  3EH2 A;  1M2V B;  3EGX A;  1M2V A;  5IVU A;  4PKI G;  1DEJ S;  1Q8X A;  3EG9 B;  1PD0 A;  1WNJ A;  2LLF A;  5HVK D;  4PKG G;  1YVN G;  1COF A;  2W0I A;  3EFO B;  1KCQ A;  5HVK B;  3FFN A;  1PCX A;  4KED A;  1ESV S;  1AK6 A;  1WFS A;  4PKH B;  1T3Y A;  1UDM A;  1YAG G;  2MP4 A;  1WM4 A;  4KEE A;  3A5N S;  3CI5 G;  2MV2 A;  2VAC A;  3EGX B;  3CIP G;  2VIK A;  1AK7 A;  1EQY S;  2MOT A;  1RGI G;  2FF6 G;  1H1V G;  1SVY A;  2FH4 A;  5KYN A;  4CBU G;  5L6W C;  1Q8G A;  2QTV A;  2L72 A;  2FH1 A;  3A5L S;  4Z94 G;  5KYY B;  5KYY A;  5FAF A;  3A5O S;  4CBW G;  2FH3 A;  1NPH A;  1HQZ 1;  1CNU A;  1C0G S;  2FH2 A;  2HD7 A;  2VIL A;  3FFK A;  1MDU A;  3CJC G;  3TU5 B;  1P8Z G;  1NMD G;  1CFY A;  1PD1 A;  1JHW A;  1T44 G;  1M2O A;  4JD2 H;  1J72 A;  5KYX B;  5KYX A;  1X67 A;  1C0F S;  1D0N A;  3CJB G;  1NM1 G;  1NLV G;  2XF1 A;  1TVJ A;  1P8X A;  3EGD B;  3EGD A;  3A5M S;  2NUT B;  2NUT A;  5A1M A;  2LXX A;  1VKK A;  2NUP B;  1QPV A;  2NUP A;  1T3X A;  4BEX 1;  5KYU A; 
#chains in the Genus database with same CATH homology
 4CBX G;  5KYU B;  3FG7 A;  1TMW A;  3L50 A;  2FF3 A;  3DA7 A;  5KYW B;  5KYW A;  3EG9 A;  2I2Q A;  1F7S A;  2XFA A;  1V6F A;  4S10 C;  1M4J A;  3EFO A;  1D4X G;  2D8B A;  3FG6 A;  5FAE A;  1AHQ A;  5DD2 A;  1T2L A;  4KEF A;  1SVQ A;  1SVR A;  4LIZ A;  3Q2B A;  2KVK A;  1VFQ A;  2FGH A;  3DAW B;  2LJ8 A;  3EH1 A;  3EH2 A;  1M2V B;  3EGX A;  1M2V A;  5IVU A;  4PKI G;  1DEJ S;  1Q8X A;  3EG9 B;  1PD0 A;  1WNJ A;  2LLF A;  5HVK D;  4PKG G;  1YVN G;  1COF A;  2W0I A;  3EFO B;  1KCQ A;  5HVK B;  3FFN A;  1PCX A;  4KED A;  1ESV S;  1AK6 A;  1WFS A;  4PKH B;  1T3Y A;  1UDM A;  1YAG G;  2MP4 A;  1WM4 A;  4KEE A;  3A5N S;  3CI5 G;  2MV2 A;  2VAC A;  3EGX B;  3CIP G;  2VIK A;  1AK7 A;  1EQY S;  2MOT A;  1RGI G;  2FF6 G;  1H1V G;  1SVY A;  2FH4 A;  5KYN A;  4CBU G;  5L6W C;  1Q8G A;  2QTV A;  2L72 A;  2FH1 A;  3A5L S;  4Z94 G;  5KYY B;  5KYY A;  5FAF A;  3A5O S;  4CBW G;  2FH3 A;  1NPH A;  1HQZ 1;  1CNU A;  1C0G S;  2FH2 A;  2HD7 A;  2VIL A;  3FFK A;  1MDU A;  3CJC G;  3TU5 B;  1P8Z G;  1NMD G;  1CFY A;  1PD1 A;  1JHW A;  1T44 G;  1M2O A;  4JD2 H;  1J72 A;  5KYX B;  5KYX A;  1X67 A;  1C0F S;  1D0N A;  3CJB G;  1NM1 G;  1NLV G;  2XF1 A;  1TVJ A;  1P8X A;  3EGD B;  3EGD A;  3A5M S;  2NUT B;  2NUT A;  5A1M A;  2LXX A;  1VKK A;  2NUP B;  1QPV A;  2NUP A;  1T3X A;  4BEX 1;  5KYU A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...