1ESV | Genus

Total Genus 39

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	39
sequence length	125
structure length	125
Chain Sequence	MVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTCLYGDFFTGDAYVILKTVQLRNGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGF

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	Latrunculin alters the actin-monomer subunit interface to prevent polymerization. pubmed doi rcsb
molecule keywords	GELSOLIN
molecule tags	Contractile protein
source organism	Homo sapiens
total genus	39
structure length	125
sequence length	125
ec nomenclature
pdb deposition date	2000-04-11

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
S	PF00626	Gelsolin	Gelsolin repeat

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.40.20.10	Alpha Beta	3-Layer(aba) Sandwich	Severin	Severin	1esvS00

1ESVS 2D8BA 2QTVA 4KEFA 2W0IA 3EFOA 5HVKB 4KEDA 1C0GS 2FH4A 5KYYA 2NUPA 1PCXA 3EG9A 1H1VG 1QPVA 1HQZ1 1P8XA 1YAGG 3DAWB 2VACA 1TMWA 4PKGG 3EGDB 1EQYS 4S10C 1M4JA 4LIZA 1AHQA 3EH2A 1C0FS 2LLFA 1VFQA 1MDUA 1P8ZG 2KVKA 2HD7A 1T3YA 2VILA 1JHWA 5KYWB 4JD2H 1M2VB 3EGDA 1DEJS 1F7SA 3A5LS 4CBWG 1TVJA 2FH3A 3CIPG 3FFKA 5HVKD 1CNUA 1KCQA 1AK7A 1SVQA 3Q2BA 1D0NA 1SVRA 1PD0A 1Q8XA 5KYWA 1M2OA 1M2VA 5KYXB 1X67A 5KYUB 2FH1A 3FG6A 1NPHA 1NM1G 1WNJA 1AK6A 2XF1A 2MP4A 2VIKA 4PKHB 3A5MS 5FAFA 3CJCG 3A5NS 3CJBG 1J72A 4PKIG 1YVNG 3EH1A 5A1MA 5KYUA 2L72A 5L6WC 1NMDG 1SVYA 2FF6G 2NUTB 2I2QA 1T2LA 1UDMA 5KYNA 1WM4A 3EGXB 5IVUA 2XFAA 1T3XA 2FF3A 2MV2A 2LJ8A 5DD2A 1CFYA 2LXXA 1WFSA 1PD1A 3FG7A 3CI5G 2NUTA 1RGIG 1COFA 4KEEA 2MOTA 2FH2A 3EGXA 1NLVG 4CBUG 3EFOB 4Z94G 1Q8GA 5KYXA 5KYYB 1VKKA 4BEX1 2NUPB 3TU5B 3FFNA 2FGHA 3A5OS 3EG9B 3L50A 1D4XG 1T44G 1V6FA 5FAEA 4CBXG
chains in the Genus database with same CATH superfamily

1ESVS 2D8BA 2QTVA 4KEFA 2W0IA 3EFOA 5HVKB 4KEDA 1C0GS 2FH4A 5KYYA 2NUPA 1PCXA 3EG9A 1H1VG 1QPVA 1HQZ1 1P8XA 1YAGG 3DAWB 2VACA 1TMWA 4PKGG 3EGDB 1EQYS 4S10C 1M4JA 4LIZA 1AHQA 3EH2A 1C0FS 2LLFA 1VFQA 1MDUA 1P8ZG 2KVKA 2HD7A 1T3YA 2VILA 1JHWA 5KYWB 4JD2H 1M2VB 3EGDA 1DEJS 1F7SA 3A5LS 4CBWG 1TVJA 2FH3A 3CIPG 3FFKA 5HVKD 1CNUA 1KCQA 1AK7A 1SVQA 3DA7A 3Q2BA 1D0NA 1SVRA 1PD0A 1Q8XA 5KYWA 1M2OA 1M2VA 5KYXB 1X67A 5KYUB 2FH1A 3FG6A 1NPHA 1NM1G 1WNJA 1AK6A 2XF1A 2MP4A 2VIKA 4PKHB 3A5MS 5FAFA 3CJCG 3A5NS 3CJBG 1J72A 4PKIG 1YVNG 3EH1A 5A1MA 5KYUA 2L72A 5L6WC 1NMDG 1SVYA 2FF6G 2NUTB 2I2QA 1T2LA 1UDMA 5KYNA 1WM4A 3EGXB 5IVUA 2XFAA 1T3XA 2FF3A 2MV2A 2LJ8A 5DD2A 1CFYA 2LXXA 1WFSA 1PD1A 3FG7A 3CI5G 2NUTA 1RGIG 1COFA 4KEEA 2MOTA 2FH2A 3EGXA 1NLVG 4CBUG 3EFOB 4Z94G 1Q8GA 5KYXA 5KYYB 1VKKA 4BEX1 2NUPB 3TU5B 3FFNA 2FGHA 3A5OS 3EG9B 3L50A 1D4XG 1T44G 1V6FA 5FAEA 4CBXG
chains in the Genus database with same CATH topology

1ESVS 2D8BA 2QTVA 4KEFA 2W0IA 3EFOA 5HVKB 4KEDA 1C0GS 2FH4A 5KYYA 2NUPA 1PCXA 3EG9A 1H1VG 1QPVA 1HQZ1 1P8XA 1YAGG 3DAWB 2VACA 1TMWA 4PKGG 3EGDB 1EQYS 4S10C 1M4JA 4LIZA 1AHQA 3EH2A 1C0FS 2LLFA 1VFQA 1MDUA 1P8ZG 2KVKA 2HD7A 1T3YA 2VILA 1JHWA 5KYWB 4JD2H 1M2VB 3EGDA 1DEJS 1F7SA 3A5LS 4CBWG 1TVJA 2FH3A 3CIPG 3FFKA 5HVKD 1CNUA 1KCQA 1AK7A 1SVQA 3DA7A 3Q2BA 1D0NA 1SVRA 1PD0A 1Q8XA 5KYWA 1M2OA 1M2VA 5KYXB 1X67A 5KYUB 2FH1A 3FG6A 1NPHA 1NM1G 1WNJA 1AK6A 2XF1A 2MP4A 2VIKA 4PKHB 3A5MS 5FAFA 3CJCG 3A5NS 3CJBG 1J72A 4PKIG 1YVNG 3EH1A 5A1MA 5KYUA 2L72A 5L6WC 1NMDG 1SVYA 2FF6G 2NUTB 2I2QA 1T2LA 1UDMA 5KYNA 1WM4A 3EGXB 5IVUA 2XFAA 1T3XA 2FF3A 2MV2A 2LJ8A 5DD2A 1CFYA 2LXXA 1WFSA 1PD1A 3FG7A 3CI5G 2NUTA 1RGIG 1COFA 4KEEA 2MOTA 2FH2A 3EGXA 1NLVG 4CBUG 3EFOB 4Z94G 1Q8GA 5KYXA 5KYYB 1VKKA 4BEX1 2NUPB 3TU5B 3FFNA 2FGHA 3A5OS 3EG9B 3L50A 1D4XG 1T44G 1V6FA 5FAEA 4CBXG
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 1ESV S;  2D8B A;  2QTV A;  4KEF A;  2W0I A;  3EFO A;  5HVK B;  4KED A;  1C0G S;  2FH4 A;  5KYY A;  2NUP A;  1PCX A;  3EG9 A;  1H1V G;  1QPV A;  1HQZ 1;  1P8X A;  1YAG G;  3DAW B;  2VAC A;  1TMW A;  4PKG G;  3EGD B;  1EQY S;  4S10 C;  1M4J A;  4LIZ A;  1AHQ A;  3EH2 A;  1C0F S;  2LLF A;  1VFQ A;  1MDU A;  1P8Z G;  2KVK A;  2HD7 A;  1T3Y A;  2VIL A;  1JHW A;  5KYW B;  4JD2 H;  1M2V B;  3EGD A;  1DEJ S;  1F7S A;  3A5L S;  4CBW G;  1TVJ A;  2FH3 A;  3CIP G;  3FFK A;  5HVK D;  1CNU A;  1KCQ A;  1AK7 A;  1SVQ A;  3Q2B A;  1D0N A;  1SVR A;  1PD0 A;  1Q8X A;  5KYW A;  1M2O A;  1M2V A;  5KYX B;  1X67 A;  5KYU B;  2FH1 A;  3FG6 A;  1NPH A;  1NM1 G;  1WNJ A;  1AK6 A;  2XF1 A;  2MP4 A;  2VIK A;  4PKH B;  3A5M S;  5FAF A;  3CJC G;  3A5N S;  3CJB G;  1J72 A;  4PKI G;  1YVN G;  3EH1 A;  5A1M A;  5KYU A;  2L72 A;  5L6W C;  1NMD G;  1SVY A;  2FF6 G;  2NUT B;  2I2Q A;  1T2L A;  1UDM A;  5KYN A;  1WM4 A;  3EGX B;  5IVU A;  2XFA A;  1T3X A;  2FF3 A;  2MV2 A;  2LJ8 A;  5DD2 A;  1CFY A;  2LXX A;  1WFS A;  1PD1 A;  3FG7 A;  3CI5 G;  2NUT A;  1RGI G;  1COF A;  4KEE A;  2MOT A;  2FH2 A;  3EGX A;  1NLV G;  4CBU G;  3EFO B;  4Z94 G;  1Q8G A;  5KYX A;  5KYY B;  1VKK A;  4BEX 1;  2NUP B;  3TU5 B;  3FFN A;  2FGH A;  3A5O S;  3EG9 B;  3L50 A;  1D4X G;  1T44 G;  1V6F A;  5FAE A;  4CBX G; 
#chains in the Genus database with same CATH topology
 1ESV S;  2D8B A;  2QTV A;  4KEF A;  2W0I A;  3EFO A;  5HVK B;  4KED A;  1C0G S;  2FH4 A;  5KYY A;  2NUP A;  1PCX A;  3EG9 A;  1H1V G;  1QPV A;  1HQZ 1;  1P8X A;  1YAG G;  3DAW B;  2VAC A;  1TMW A;  4PKG G;  3EGD B;  1EQY S;  4S10 C;  1M4J A;  4LIZ A;  1AHQ A;  3EH2 A;  1C0F S;  2LLF A;  1VFQ A;  1MDU A;  1P8Z G;  2KVK A;  2HD7 A;  1T3Y A;  2VIL A;  1JHW A;  5KYW B;  4JD2 H;  1M2V B;  3EGD A;  1DEJ S;  1F7S A;  3A5L S;  4CBW G;  1TVJ A;  2FH3 A;  3CIP G;  3FFK A;  5HVK D;  1CNU A;  1KCQ A;  1AK7 A;  1SVQ A;  3DA7 A;  3Q2B A;  1D0N A;  1SVR A;  1PD0 A;  1Q8X A;  5KYW A;  1M2O A;  1M2V A;  5KYX B;  1X67 A;  5KYU B;  2FH1 A;  3FG6 A;  1NPH A;  1NM1 G;  1WNJ A;  1AK6 A;  2XF1 A;  2MP4 A;  2VIK A;  4PKH B;  3A5M S;  5FAF A;  3CJC G;  3A5N S;  3CJB G;  1J72 A;  4PKI G;  1YVN G;  3EH1 A;  5A1M A;  5KYU A;  2L72 A;  5L6W C;  1NMD G;  1SVY A;  2FF6 G;  2NUT B;  2I2Q A;  1T2L A;  1UDM A;  5KYN A;  1WM4 A;  3EGX B;  5IVU A;  2XFA A;  1T3X A;  2FF3 A;  2MV2 A;  2LJ8 A;  5DD2 A;  1CFY A;  2LXX A;  1WFS A;  1PD1 A;  3FG7 A;  3CI5 G;  2NUT A;  1RGI G;  1COF A;  4KEE A;  2MOT A;  2FH2 A;  3EGX A;  1NLV G;  4CBU G;  3EFO B;  4Z94 G;  1Q8G A;  5KYX A;  5KYY B;  1VKK A;  4BEX 1;  2NUP B;  3TU5 B;  3FFN A;  2FGH A;  3A5O S;  3EG9 B;  3L50 A;  1D4X G;  1T44 G;  1V6F A;  5FAE A;  4CBX G; 
#chains in the Genus database with same CATH homology
 1ESV S;  2D8B A;  2QTV A;  4KEF A;  2W0I A;  3EFO A;  5HVK B;  4KED A;  1C0G S;  2FH4 A;  5KYY A;  2NUP A;  1PCX A;  3EG9 A;  1H1V G;  1QPV A;  1HQZ 1;  1P8X A;  1YAG G;  3DAW B;  2VAC A;  1TMW A;  4PKG G;  3EGD B;  1EQY S;  4S10 C;  1M4J A;  4LIZ A;  1AHQ A;  3EH2 A;  1C0F S;  2LLF A;  1VFQ A;  1MDU A;  1P8Z G;  2KVK A;  2HD7 A;  1T3Y A;  2VIL A;  1JHW A;  5KYW B;  4JD2 H;  1M2V B;  3EGD A;  1DEJ S;  1F7S A;  3A5L S;  4CBW G;  1TVJ A;  2FH3 A;  3CIP G;  3FFK A;  5HVK D;  1CNU A;  1KCQ A;  1AK7 A;  1SVQ A;  3DA7 A;  3Q2B A;  1D0N A;  1SVR A;  1PD0 A;  1Q8X A;  5KYW A;  1M2O A;  1M2V A;  5KYX B;  1X67 A;  5KYU B;  2FH1 A;  3FG6 A;  1NPH A;  1NM1 G;  1WNJ A;  1AK6 A;  2XF1 A;  2MP4 A;  2VIK A;  4PKH B;  3A5M S;  5FAF A;  3CJC G;  3A5N S;  3CJB G;  1J72 A;  4PKI G;  1YVN G;  3EH1 A;  5A1M A;  5KYU A;  2L72 A;  5L6W C;  1NMD G;  1SVY A;  2FF6 G;  2NUT B;  2I2Q A;  1T2L A;  1UDM A;  5KYN A;  1WM4 A;  3EGX B;  5IVU A;  2XFA A;  1T3X A;  2FF3 A;  2MV2 A;  2LJ8 A;  5DD2 A;  1CFY A;  2LXX A;  1WFS A;  1PD1 A;  3FG7 A;  3CI5 G;  2NUT A;  1RGI G;  1COF A;  4KEE A;  2MOT A;  2FH2 A;  3EGX A;  1NLV G;  4CBU G;  3EFO B;  4Z94 G;  1Q8G A;  5KYX A;  5KYY B;  1VKK A;  4BEX 1;  2NUP B;  3TU5 B;  3FFN A;  2FGH A;  3A5O S;  3EG9 B;  3L50 A;  1D4X G;  1T44 G;  1V6F A;  5FAE A;  4CBX G;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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1ESVS

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations