1J72A

Crystal structure of mutant macrophage capping protein (cap g) with actin-severing activity in the ca2+-free form
Total Genus 83
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
83
sequence length
337
structure length
337
Chain Sequence
PFPGSVQDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEEVSHLHLWIGQQSSRDEQGACAVLAVQLDDYLGGRPVQHREVQGNESDLFMSYFPRGLKYQEGGVESGFKHVVPNEVVVQRLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPAEMIQVLGPKPALKEGNPEEDLTADKANAQAAALYKVSDATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIYIWKGRKANEKERQAALQVAEGFISRMQYAPNTQVEILPQGRESPIFKQFFKDWK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of Mutant Human Macrophage Capping Protein
rcsb
molecule tags Structural protein
source organism Homo sapiens
molecule keywords Macrophage capping protein
total genus 83
structure length 337
sequence length 337
ec nomenclature
pdb deposition date 2001-05-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00626 Gelsolin Gelsolin repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 1j72A02
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 1j72A03
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 1j72A01
2FH2A 3FFNA 3EH1A 2NUTB 4CBXG 5FAEA 2FH1A 3A5MS 2QTVA 2L72A 5KYYA 3L50A 1YAGG 1PD1A 5KYXB 1WFSA 1D0NA 1M4JA 2MP4A 2NUPB 1VKKA 1T3XA 1X67A 3EG9B 1KCQA 4CBUG 3A5LS 3EFOB 1PCXA 3CJCG 4BEX1 1V6FA 3FFKA 4Z94G 1P8ZG 5HVKB 3FG7A 5KYUA 1COFA 2LJ8A 4LIZA 3EH2A 2VACA 1NLVG 3EGDA 1UDMA 1TVJA 3TU5B 1T2LA 5KYYB 1M2VA 1NM1G 1AK7A 3CI5G 1P8XA 3EGXB 1MDUA 1C0GS 4PKIG 4JD2H 2XF1A 1HQZ1 2LLFA 5DD2A 5KYNA 4S10C 2D8BA 1ESVS 5HVKD 5A1MA 1QPVA 2FF6G 1SVQA 2NUTA 1RGIG 2HD7A 1DEJS 1AK6A 1SVRA 2VIKA 5L6WC 1M2VB 1H1VG 1SVYA 2NUPA 3DAWB 3A5OS 3EG9A 1M2OA 3CJBG 2MV2A 4CBWG 4PKGG 1JHWA 2W0IA 2XFAA 2FGHA 3A5NS 3FG6A 1CNUA 1T3YA 1F7SA 5KYWA 1EQYS 1YVNG 2VILA 4PKHB 5IVUA 5FAFA 5KYUB 1TMWA 4KEDA 2LXXA 3EGDB 1C0FS 3EGXA 5KYXA 2MOTA 1NPHA 1J72A 1D4XG 4KEEA 2FF3A 1WM4A 1VFQA 1AHQA 2FH3A 1Q8GA 3EFOA 1T44G 3Q2BA 1PD0A 1Q8XA 4KEFA 3CIPG 5KYWB 1WNJA 1NMDG 2FH4A 1CFYA 2I2QA 2KVKA
chains in the Genus database with same CATH superfamily
2FH2A 3FFNA 3EH1A 2NUTB 4CBXG 5FAEA 2FH1A 3A5MS 2QTVA 2L72A 5KYYA 3L50A 1YAGG 1PD1A 5KYXB 1WFSA 1D0NA 1M4JA 2MP4A 2NUPB 1VKKA 1T3XA 1X67A 3EG9B 1KCQA 4CBUG 3A5LS 3EFOB 1PCXA 3CJCG 4BEX1 1V6FA 3FFKA 4Z94G 1P8ZG 5HVKB 3FG7A 5KYUA 1COFA 2LJ8A 4LIZA 3EH2A 2VACA 1NLVG 3EGDA 1UDMA 1TVJA 3TU5B 1T2LA 5KYYB 1M2VA 1NM1G 1AK7A 3CI5G 1P8XA 3EGXB 1MDUA 1C0GS 4PKIG 4JD2H 2XF1A 1HQZ1 2LLFA 5DD2A 5KYNA 4S10C 2D8BA 1ESVS 5HVKD 5A1MA 1QPVA 2FF6G 1SVQA 2NUTA 1RGIG 2HD7A 1DEJS 1AK6A 1SVRA 2VIKA 5L6WC 1M2VB 1H1VG 1SVYA 2NUPA 3DAWB 3A5OS 3EG9A 1M2OA 3CJBG 2MV2A 4CBWG 4PKGG 1JHWA 2W0IA 2XFAA 2FGHA 3A5NS 3FG6A 1CNUA 1T3YA 1F7SA 5KYWA 1EQYS 1YVNG 2VILA 4PKHB 5IVUA 5FAFA 5KYUB 1TMWA 4KEDA 2LXXA 3EGDB 3DA7A 1C0FS 3EGXA 5KYXA 2MOTA 1NPHA 1J72A 1D4XG 4KEEA 2FF3A 1WM4A 1VFQA 1AHQA 2FH3A 1Q8GA 3EFOA 1T44G 3Q2BA 1PD0A 1Q8XA 4KEFA 3CIPG 5KYWB 1WNJA 1NMDG 2FH4A 1CFYA 2I2QA 2KVKA
chains in the Genus database with same CATH topology
2FH2A 3FFNA 3EH1A 2NUTB 4CBXG 5FAEA 2FH1A 3A5MS 2QTVA 2L72A 5KYYA 3L50A 1YAGG 1PD1A 5KYXB 1WFSA 1D0NA 1M4JA 2MP4A 2NUPB 1VKKA 1T3XA 1X67A 3EG9B 1KCQA 4CBUG 3A5LS 3EFOB 1PCXA 3CJCG 4BEX1 1V6FA 3FFKA 4Z94G 1P8ZG 5HVKB 3FG7A 5KYUA 1COFA 2LJ8A 4LIZA 3EH2A 2VACA 1NLVG 3EGDA 1UDMA 1TVJA 3TU5B 1T2LA 5KYYB 1M2VA 1NM1G 1AK7A 3CI5G 1P8XA 3EGXB 1MDUA 1C0GS 4PKIG 4JD2H 2XF1A 1HQZ1 2LLFA 5DD2A 5KYNA 4S10C 2D8BA 1ESVS 5HVKD 5A1MA 1QPVA 2FF6G 1SVQA 2NUTA 1RGIG 2HD7A 1DEJS 1AK6A 1SVRA 2VIKA 5L6WC 1M2VB 1H1VG 1SVYA 2NUPA 3DAWB 3A5OS 3EG9A 1M2OA 3CJBG 2MV2A 4CBWG 4PKGG 1JHWA 2W0IA 2XFAA 2FGHA 3A5NS 3FG6A 1CNUA 1T3YA 1F7SA 5KYWA 1EQYS 1YVNG 2VILA 4PKHB 5IVUA 5FAFA 5KYUB 1TMWA 4KEDA 2LXXA 3EGDB 3DA7A 1C0FS 3EGXA 5KYXA 2MOTA 1NPHA 1J72A 1D4XG 4KEEA 2FF3A 1WM4A 1VFQA 1AHQA 2FH3A 1Q8GA 3EFOA 1T44G 3Q2BA 1PD0A 1Q8XA 4KEFA 3CIPG 5KYWB 1WNJA 1NMDG 2FH4A 1CFYA 2I2QA 2KVKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2FH2 A;  3FFN A;  3EH1 A;  2NUT B;  4CBX G;  5FAE A;  2FH1 A;  3A5M S;  2QTV A;  2L72 A;  5KYY A;  3L50 A;  1YAG G;  1PD1 A;  5KYX B;  1WFS A;  1D0N A;  1M4J A;  2MP4 A;  2NUP B;  1VKK A;  1T3X A;  1X67 A;  3EG9 B;  1KCQ A;  4CBU G;  3A5L S;  3EFO B;  1PCX A;  3CJC G;  4BEX 1;  1V6F A;  3FFK A;  4Z94 G;  1P8Z G;  5HVK B;  3FG7 A;  5KYU A;  1COF A;  2LJ8 A;  4LIZ A;  3EH2 A;  2VAC A;  1NLV G;  3EGD A;  1UDM A;  1TVJ A;  3TU5 B;  1T2L A;  5KYY B;  1M2V A;  1NM1 G;  1AK7 A;  3CI5 G;  1P8X A;  3EGX B;  1MDU A;  1C0G S;  4PKI G;  4JD2 H;  2XF1 A;  1HQZ 1;  2LLF A;  5DD2 A;  5KYN A;  4S10 C;  2D8B A;  1ESV S;  5HVK D;  5A1M A;  1QPV A;  2FF6 G;  1SVQ A;  2NUT A;  1RGI G;  2HD7 A;  1DEJ S;  1AK6 A;  1SVR A;  2VIK A;  5L6W C;  1M2V B;  1H1V G;  1SVY A;  2NUP A;  3DAW B;  3A5O S;  3EG9 A;  1M2O A;  3CJB G;  2MV2 A;  4CBW G;  4PKG G;  1JHW A;  2W0I A;  2XFA A;  2FGH A;  3A5N S;  3FG6 A;  1CNU A;  1T3Y A;  1F7S A;  5KYW A;  1EQY S;  1YVN G;  2VIL A;  4PKH B;  5IVU A;  5FAF A;  5KYU B;  1TMW A;  4KED A;  2LXX A;  3EGD B;  1C0F S;  3EGX A;  5KYX A;  2MOT A;  1NPH A;  1J72 A;  1D4X G;  4KEE A;  2FF3 A;  1WM4 A;  1VFQ A;  1AHQ A;  2FH3 A;  1Q8G A;  3EFO A;  1T44 G;  3Q2B A;  1PD0 A;  1Q8X A;  4KEF A;  3CIP G;  5KYW B;  1WNJ A;  1NMD G;  2FH4 A;  1CFY A;  2I2Q A;  2KVK A; 
#chains in the Genus database with same CATH topology
 2FH2 A;  3FFN A;  3EH1 A;  2NUT B;  4CBX G;  5FAE A;  2FH1 A;  3A5M S;  2QTV A;  2L72 A;  5KYY A;  3L50 A;  1YAG G;  1PD1 A;  5KYX B;  1WFS A;  1D0N A;  1M4J A;  2MP4 A;  2NUP B;  1VKK A;  1T3X A;  1X67 A;  3EG9 B;  1KCQ A;  4CBU G;  3A5L S;  3EFO B;  1PCX A;  3CJC G;  4BEX 1;  1V6F A;  3FFK A;  4Z94 G;  1P8Z G;  5HVK B;  3FG7 A;  5KYU A;  1COF A;  2LJ8 A;  4LIZ A;  3EH2 A;  2VAC A;  1NLV G;  3EGD A;  1UDM A;  1TVJ A;  3TU5 B;  1T2L A;  5KYY B;  1M2V A;  1NM1 G;  1AK7 A;  3CI5 G;  1P8X A;  3EGX B;  1MDU A;  1C0G S;  4PKI G;  4JD2 H;  2XF1 A;  1HQZ 1;  2LLF A;  5DD2 A;  5KYN A;  4S10 C;  2D8B A;  1ESV S;  5HVK D;  5A1M A;  1QPV A;  2FF6 G;  1SVQ A;  2NUT A;  1RGI G;  2HD7 A;  1DEJ S;  1AK6 A;  1SVR A;  2VIK A;  5L6W C;  1M2V B;  1H1V G;  1SVY A;  2NUP A;  3DAW B;  3A5O S;  3EG9 A;  1M2O A;  3CJB G;  2MV2 A;  4CBW G;  4PKG G;  1JHW A;  2W0I A;  2XFA A;  2FGH A;  3A5N S;  3FG6 A;  1CNU A;  1T3Y A;  1F7S A;  5KYW A;  1EQY S;  1YVN G;  2VIL A;  4PKH B;  5IVU A;  5FAF A;  5KYU B;  1TMW A;  4KED A;  2LXX A;  3EGD B;  3DA7 A;  1C0F S;  3EGX A;  5KYX A;  2MOT A;  1NPH A;  1J72 A;  1D4X G;  4KEE A;  2FF3 A;  1WM4 A;  1VFQ A;  1AHQ A;  2FH3 A;  1Q8G A;  3EFO A;  1T44 G;  3Q2B A;  1PD0 A;  1Q8X A;  4KEF A;  3CIP G;  5KYW B;  1WNJ A;  1NMD G;  2FH4 A;  1CFY A;  2I2Q A;  2KVK A; 
#chains in the Genus database with same CATH homology
 2FH2 A;  3FFN A;  3EH1 A;  2NUT B;  4CBX G;  5FAE A;  2FH1 A;  3A5M S;  2QTV A;  2L72 A;  5KYY A;  3L50 A;  1YAG G;  1PD1 A;  5KYX B;  1WFS A;  1D0N A;  1M4J A;  2MP4 A;  2NUP B;  1VKK A;  1T3X A;  1X67 A;  3EG9 B;  1KCQ A;  4CBU G;  3A5L S;  3EFO B;  1PCX A;  3CJC G;  4BEX 1;  1V6F A;  3FFK A;  4Z94 G;  1P8Z G;  5HVK B;  3FG7 A;  5KYU A;  1COF A;  2LJ8 A;  4LIZ A;  3EH2 A;  2VAC A;  1NLV G;  3EGD A;  1UDM A;  1TVJ A;  3TU5 B;  1T2L A;  5KYY B;  1M2V A;  1NM1 G;  1AK7 A;  3CI5 G;  1P8X A;  3EGX B;  1MDU A;  1C0G S;  4PKI G;  4JD2 H;  2XF1 A;  1HQZ 1;  2LLF A;  5DD2 A;  5KYN A;  4S10 C;  2D8B A;  1ESV S;  5HVK D;  5A1M A;  1QPV A;  2FF6 G;  1SVQ A;  2NUT A;  1RGI G;  2HD7 A;  1DEJ S;  1AK6 A;  1SVR A;  2VIK A;  5L6W C;  1M2V B;  1H1V G;  1SVY A;  2NUP A;  3DAW B;  3A5O S;  3EG9 A;  1M2O A;  3CJB G;  2MV2 A;  4CBW G;  4PKG G;  1JHW A;  2W0I A;  2XFA A;  2FGH A;  3A5N S;  3FG6 A;  1CNU A;  1T3Y A;  1F7S A;  5KYW A;  1EQY S;  1YVN G;  2VIL A;  4PKH B;  5IVU A;  5FAF A;  5KYU B;  1TMW A;  4KED A;  2LXX A;  3EGD B;  3DA7 A;  1C0F S;  3EGX A;  5KYX A;  2MOT A;  1NPH A;  1J72 A;  1D4X G;  4KEE A;  2FF3 A;  1WM4 A;  1VFQ A;  1AHQ A;  2FH3 A;  1Q8G A;  3EFO A;  1T44 G;  3Q2B A;  1PD0 A;  1Q8X A;  4KEF A;  3CIP G;  5KYW B;  1WNJ A;  1NMD G;  2FH4 A;  1CFY A;  2I2Q A;  2KVK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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