1JHW | Genus

Total Genus 78

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	78
sequence length	336
structure length	326
Chain Sequence	PFPGSVQDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEEVSHLHLWIGQQSSRDEQGACAVLAVQLDDYLGGRPVQHREVQGNESDLFMSYFPRGLKYQEGGVESGFKHVVPNEVVVQRLYQVKGAKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPAEMIQVLGPKPALKEGNPAQAAALYKVSDATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIYIWKGRKANEKERQAALQVAEGFISRMQYAPNTQVEILPQGRESPIFKQFFKDW

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	Crystal Structure of Mutant Human Macrophage Capping Protein rcsb
molecule keywords	MACROPHAGE CAPPING PROTEIN
molecule tags	Structural protein
source organism	Homo sapiens
total genus	78
structure length	326
sequence length	336
ec nomenclature
pdb deposition date	2001-06-28

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00626	Gelsolin	Gelsolin repeat

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.40.20.10	Alpha Beta	3-Layer(aba) Sandwich	Severin	Severin	1jhwA02
3.40.20.10	Alpha Beta	3-Layer(aba) Sandwich	Severin	Severin	1jhwA03
3.40.20.10	Alpha Beta	3-Layer(aba) Sandwich	Severin	Severin	1jhwA01

2FF3A 5KYWB 2I2QA 2FF6G 1H1VG 1C0GS 4KEFA 1WNJA 3EGDA 5KYWA 1ESVS 3EGXB 1TMWA 1TVJA 1V6FA 2NUTB 5KYNA 3CJCG 1YAGG 3A5NS 1T3YA 5KYUB 5KYXB 1F7SA 2FH2A 2LXXA 2XFAA 2L72A 2MOTA 1DEJS 2HD7A 1KCQA 5KYUA 5KYXA 2QTVA 1M2OA 3EGDB 1RGIG 5FAEA 4PKIG 1Q8GA 1SVYA 1PCXA 1J72A 1YVNG 4Z94G 1AK7A 3A5LS 3FFNA 4PKGG 4CBUG 1X67A 3CJBG 4S10C 2LJ8A 1Q8XA 3EFOB 1MDUA 5DD2A 1AK6A 3EG9B 2LLFA 1NMDG 3CI5G 1D4XG 3A5OS 3EH1A 3EFOA 4CBWG 5L6WC 1EQYS 5A1MA 3EG9A 2D8BA 1M2VA 1P8XA 1T44G 4KEDA 1NLVG 1WFSA 4BEX1 1WM4A 2FH1A 4CBXG 3FG6A 2VIKA 5KYYB 4KEEA 1SVRA 2FGHA 2KVKA 4LIZA 1SVQA 4PKHB 1T2LA 1C0FS 1JHWA 5KYYA 3EH2A 1UDMA 1QPVA 2FH3A 2NUPB 5HVKD 1M2VB 2XF1A 5IVUA 4JD2H 1M4JA 2W0IA 1PD0A 1VFQA 1D0NA 3FG7A 1PD1A 5FAFA 2NUPA 1HQZ1 3L50A 1VKKA 1P8ZG 1COFA 2MP4A 3CIPG 2VILA 3A5MS 3EGXA 3Q2BA 2MV2A 2NUTA 1T3XA 3DAWB 3TU5B 1NPHA 2VACA 5HVKB 1CNUA 3FFKA 1AHQA 1NM1G 1CFYA 2FH4A
chains in the Genus database with same CATH superfamily

2FF3A 5KYWB 2I2QA 2FF6G 1H1VG 1C0GS 4KEFA 1WNJA 3EGDA 5KYWA 1ESVS 3EGXB 1TMWA 1TVJA 1V6FA 3DA7A 2NUTB 5KYNA 3CJCG 1YAGG 3A5NS 1T3YA 5KYUB 5KYXB 1F7SA 2FH2A 2LXXA 2XFAA 2L72A 2MOTA 1DEJS 2HD7A 1KCQA 5KYUA 5KYXA 2QTVA 1M2OA 3EGDB 1RGIG 5FAEA 4PKIG 1Q8GA 1SVYA 1PCXA 1J72A 1YVNG 4Z94G 1AK7A 3A5LS 3FFNA 4PKGG 4CBUG 1X67A 3CJBG 4S10C 2LJ8A 1Q8XA 3EFOB 1MDUA 5DD2A 1AK6A 3EG9B 2LLFA 1NMDG 3CI5G 1D4XG 3A5OS 3EH1A 3EFOA 4CBWG 5L6WC 1EQYS 5A1MA 3EG9A 2D8BA 1M2VA 1P8XA 1T44G 4KEDA 1NLVG 1WFSA 4BEX1 1WM4A 2FH1A 4CBXG 3FG6A 2VIKA 5KYYB 4KEEA 1SVRA 2FGHA 2KVKA 4LIZA 1SVQA 4PKHB 1T2LA 1C0FS 1JHWA 5KYYA 3EH2A 1UDMA 1QPVA 2FH3A 2NUPB 5HVKD 1M2VB 2XF1A 5IVUA 4JD2H 1M4JA 2W0IA 1PD0A 1VFQA 1D0NA 3FG7A 1PD1A 5FAFA 2NUPA 1HQZ1 3L50A 1VKKA 1P8ZG 1COFA 2MP4A 3CIPG 2VILA 3A5MS 3EGXA 3Q2BA 2MV2A 2NUTA 1T3XA 3DAWB 3TU5B 1NPHA 2VACA 5HVKB 1CNUA 3FFKA 1AHQA 1NM1G 1CFYA 2FH4A
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 2FF3 A;  5KYW B;  2I2Q A;  2FF6 G;  1H1V G;  1C0G S;  4KEF A;  1WNJ A;  3EGD A;  5KYW A;  1ESV S;  3EGX B;  1TMW A;  1TVJ A;  1V6F A;  2NUT B;  5KYN A;  3CJC G;  1YAG G;  3A5N S;  1T3Y A;  5KYU B;  5KYX B;  1F7S A;  2FH2 A;  2LXX A;  2XFA A;  2L72 A;  2MOT A;  1DEJ S;  2HD7 A;  1KCQ A;  5KYU A;  5KYX A;  2QTV A;  1M2O A;  3EGD B;  1RGI G;  5FAE A;  4PKI G;  1Q8G A;  1SVY A;  1PCX A;  1J72 A;  1YVN G;  4Z94 G;  1AK7 A;  3A5L S;  3FFN A;  4PKG G;  4CBU G;  1X67 A;  3CJB G;  4S10 C;  2LJ8 A;  1Q8X A;  3EFO B;  1MDU A;  5DD2 A;  1AK6 A;  3EG9 B;  2LLF A;  1NMD G;  3CI5 G;  1D4X G;  3A5O S;  3EH1 A;  3EFO A;  4CBW G;  5L6W C;  1EQY S;  5A1M A;  3EG9 A;  2D8B A;  1M2V A;  1P8X A;  1T44 G;  4KED A;  1NLV G;  1WFS A;  4BEX 1;  1WM4 A;  2FH1 A;  4CBX G;  3FG6 A;  2VIK A;  5KYY B;  4KEE A;  1SVR A;  2FGH A;  2KVK A;  4LIZ A;  1SVQ A;  4PKH B;  1T2L A;  1C0F S;  1JHW A;  5KYY A;  3EH2 A;  1UDM A;  1QPV A;  2FH3 A;  2NUP B;  5HVK D;  1M2V B;  2XF1 A;  5IVU A;  4JD2 H;  1M4J A;  2W0I A;  1PD0 A;  1VFQ A;  1D0N A;  3FG7 A;  1PD1 A;  5FAF A;  2NUP A;  1HQZ 1;  3L50 A;  1VKK A;  1P8Z G;  1COF A;  2MP4 A;  3CIP G;  2VIL A;  3A5M S;  3EGX A;  3Q2B A;  2MV2 A;  2NUT A;  1T3X A;  3DAW B;  3TU5 B;  1NPH A;  2VAC A;  5HVK B;  1CNU A;  3FFK A;  1AHQ A;  1NM1 G;  1CFY A;  2FH4 A; 
#chains in the Genus database with same CATH topology
 2FF3 A;  5KYW B;  2I2Q A;  2FF6 G;  1H1V G;  1C0G S;  4KEF A;  1WNJ A;  3EGD A;  5KYW A;  1ESV S;  3EGX B;  1TMW A;  1TVJ A;  1V6F A;  3DA7 A;  2NUT B;  5KYN A;  3CJC G;  1YAG G;  3A5N S;  1T3Y A;  5KYU B;  5KYX B;  1F7S A;  2FH2 A;  2LXX A;  2XFA A;  2L72 A;  2MOT A;  1DEJ S;  2HD7 A;  1KCQ A;  5KYU A;  5KYX A;  2QTV A;  1M2O A;  3EGD B;  1RGI G;  5FAE A;  4PKI G;  1Q8G A;  1SVY A;  1PCX A;  1J72 A;  1YVN G;  4Z94 G;  1AK7 A;  3A5L S;  3FFN A;  4PKG G;  4CBU G;  1X67 A;  3CJB G;  4S10 C;  2LJ8 A;  1Q8X A;  3EFO B;  1MDU A;  5DD2 A;  1AK6 A;  3EG9 B;  2LLF A;  1NMD G;  3CI5 G;  1D4X G;  3A5O S;  3EH1 A;  3EFO A;  4CBW G;  5L6W C;  1EQY S;  5A1M A;  3EG9 A;  2D8B A;  1M2V A;  1P8X A;  1T44 G;  4KED A;  1NLV G;  1WFS A;  4BEX 1;  1WM4 A;  2FH1 A;  4CBX G;  3FG6 A;  2VIK A;  5KYY B;  4KEE A;  1SVR A;  2FGH A;  2KVK A;  4LIZ A;  1SVQ A;  4PKH B;  1T2L A;  1C0F S;  1JHW A;  5KYY A;  3EH2 A;  1UDM A;  1QPV A;  2FH3 A;  2NUP B;  5HVK D;  1M2V B;  2XF1 A;  5IVU A;  4JD2 H;  1M4J A;  2W0I A;  1PD0 A;  1VFQ A;  1D0N A;  3FG7 A;  1PD1 A;  5FAF A;  2NUP A;  1HQZ 1;  3L50 A;  1VKK A;  1P8Z G;  1COF A;  2MP4 A;  3CIP G;  2VIL A;  3A5M S;  3EGX A;  3Q2B A;  2MV2 A;  2NUT A;  1T3X A;  3DAW B;  3TU5 B;  1NPH A;  2VAC A;  5HVK B;  1CNU A;  3FFK A;  1AHQ A;  1NM1 G;  1CFY A;  2FH4 A; 
#chains in the Genus database with same CATH homology
 2FF3 A;  5KYW B;  2I2Q A;  2FF6 G;  1H1V G;  1C0G S;  4KEF A;  1WNJ A;  3EGD A;  5KYW A;  1ESV S;  3EGX B;  1TMW A;  1TVJ A;  1V6F A;  3DA7 A;  2NUT B;  5KYN A;  3CJC G;  1YAG G;  3A5N S;  1T3Y A;  5KYU B;  5KYX B;  1F7S A;  2FH2 A;  2LXX A;  2XFA A;  2L72 A;  2MOT A;  1DEJ S;  2HD7 A;  1KCQ A;  5KYU A;  5KYX A;  2QTV A;  1M2O A;  3EGD B;  1RGI G;  5FAE A;  4PKI G;  1Q8G A;  1SVY A;  1PCX A;  1J72 A;  1YVN G;  4Z94 G;  1AK7 A;  3A5L S;  3FFN A;  4PKG G;  4CBU G;  1X67 A;  3CJB G;  4S10 C;  2LJ8 A;  1Q8X A;  3EFO B;  1MDU A;  5DD2 A;  1AK6 A;  3EG9 B;  2LLF A;  1NMD G;  3CI5 G;  1D4X G;  3A5O S;  3EH1 A;  3EFO A;  4CBW G;  5L6W C;  1EQY S;  5A1M A;  3EG9 A;  2D8B A;  1M2V A;  1P8X A;  1T44 G;  4KED A;  1NLV G;  1WFS A;  4BEX 1;  1WM4 A;  2FH1 A;  4CBX G;  3FG6 A;  2VIK A;  5KYY B;  4KEE A;  1SVR A;  2FGH A;  2KVK A;  4LIZ A;  1SVQ A;  4PKH B;  1T2L A;  1C0F S;  1JHW A;  5KYY A;  3EH2 A;  1UDM A;  1QPV A;  2FH3 A;  2NUP B;  5HVK D;  1M2V B;  2XF1 A;  5IVU A;  4JD2 H;  1M4J A;  2W0I A;  1PD0 A;  1VFQ A;  1D0N A;  3FG7 A;  1PD1 A;  5FAF A;  2NUP A;  1HQZ 1;  3L50 A;  1VKK A;  1P8Z G;  1COF A;  2MP4 A;  3CIP G;  2VIL A;  3A5M S;  3EGX A;  3Q2B A;  2MV2 A;  2NUT A;  1T3X A;  3DAW B;  3TU5 B;  1NPH A;  2VAC A;  5HVK B;  1CNU A;  3FFK A;  1AHQ A;  1NM1 G;  1CFY A;  2FH4 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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1JHWA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations