1P8ZG

Complex between rabbit muscle alpha-actin: human gelsolin residues val26-glu156
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
131
structure length
131
Chain Sequence
VVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGFKHVVPNE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title From the First to the second domain of gelsolin: A common path on the surface of actin?
pubmed doi rcsb
molecule tags Structural protein/contractile protein
source organism Homo sapiens
molecule keywords Gelsolin precursor, plasma
total genus 38
structure length 131
sequence length 131
ec nomenclature
pdb deposition date 2003-05-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
G PF00626 Gelsolin Gelsolin repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 1p8zG00
3EFOA 5A1MA 5KYYA 4KEEA 3EGXB 1MDUA 2XFAA 3A5MS 4KEDA 3EGDB 1JHWA 3A5OS 5KYXB 1EQYS 3EH2A 1VKKA 2XF1A 1AK6A 5FAFA 2L72A 5DD2A 4KEFA 4CBWG 3EG9B 1M2VB 2KVKA 1C0FS 2NUPA 1T3YA 2LJ8A 1CNUA 3EGXA 1M4JA 2FH3A 3EH1A 3EGDA 5KYWB 3Q2BA 3CJCG 5KYXA 1PD0A 3CJBG 1Q8XA 5HVKB 5FAEA 1DEJS 4S10C 1RGIG 1HQZ1 5KYUB 1CFYA 2LXXA 1VFQA 4CBUG 1WFSA 1KCQA 3CIPG 3EG9A 1P8ZG 1M2VA 1ESVS 4LIZA 1SVRA 1P8XA 2FH1A 2MOTA 2HD7A 4Z94G 1NPHA 5HVKD 5IVUA 2MP4A 3FG6A 3FFNA 5KYWA 2NUTB 1NM1G 3TU5B 3A5NS 4PKGG 1H1VG 2FF6G 1D0NA 1COFA 2MV2A 3CI5G 1SVQA 2LLFA 2VILA 4PKIG 5KYUA 3FG7A 1WM4A 1V6FA 1C0GS 2FF3A 1YAGG 2VIKA 1M2OA 1YVNG 1X67A 2W0IA 2D8BA 1J72A 2FH4A 2VACA 1AHQA 2I2QA 4BEX1 2NUTA 2FH2A 1UDMA 5KYNA 3EFOB 1NLVG 5KYYB 1QPVA 4JD2H 1NMDG 1PCXA 1D4XG 1SVYA 1T2LA 3DAWB 3FFKA 1F7SA 1TVJA 4CBXG 2FGHA 1T3XA 3A5LS 2QTVA 1T44G 5L6WC 3L50A 1AK7A 1Q8GA 1WNJA 2NUPB 1PD1A 4PKHB 1TMWA
chains in the Genus database with same CATH superfamily
3EFOA 5A1MA 3DA7A 5KYYA 4KEEA 3EGXB 1MDUA 2XFAA 3A5MS 4KEDA 3EGDB 1JHWA 3A5OS 5KYXB 1EQYS 3EH2A 1VKKA 2XF1A 1AK6A 5FAFA 2L72A 5DD2A 4KEFA 4CBWG 3EG9B 1M2VB 2KVKA 1C0FS 2NUPA 1T3YA 2LJ8A 1CNUA 3EGXA 1M4JA 2FH3A 3EH1A 3EGDA 5KYWB 3Q2BA 3CJCG 5KYXA 1PD0A 3CJBG 1Q8XA 5HVKB 5FAEA 1DEJS 4S10C 1RGIG 1HQZ1 5KYUB 1CFYA 2LXXA 1VFQA 4CBUG 1WFSA 1KCQA 3CIPG 3EG9A 1P8ZG 1M2VA 1ESVS 4LIZA 1SVRA 1P8XA 2FH1A 2MOTA 2HD7A 4Z94G 1NPHA 5HVKD 5IVUA 2MP4A 3FG6A 3FFNA 5KYWA 2NUTB 1NM1G 3TU5B 3A5NS 4PKGG 1H1VG 2FF6G 1D0NA 1COFA 2MV2A 3CI5G 1SVQA 2LLFA 2VILA 4PKIG 5KYUA 3FG7A 1WM4A 1V6FA 1C0GS 2FF3A 1YAGG 2VIKA 1M2OA 1YVNG 1X67A 2W0IA 2D8BA 1J72A 2FH4A 2VACA 1AHQA 2I2QA 4BEX1 2NUTA 2FH2A 1UDMA 5KYNA 3EFOB 1NLVG 5KYYB 1QPVA 4JD2H 1NMDG 1PCXA 1D4XG 1SVYA 1T2LA 3DAWB 3FFKA 1F7SA 1TVJA 4CBXG 2FGHA 1T3XA 3A5LS 2QTVA 1T44G 5L6WC 3L50A 1AK7A 1Q8GA 1WNJA 2NUPB 1PD1A 4PKHB 1TMWA
chains in the Genus database with same CATH topology
3EFOA 5A1MA 3DA7A 5KYYA 4KEEA 3EGXB 1MDUA 2XFAA 3A5MS 4KEDA 3EGDB 1JHWA 3A5OS 5KYXB 1EQYS 3EH2A 1VKKA 2XF1A 1AK6A 5FAFA 2L72A 5DD2A 4KEFA 4CBWG 3EG9B 1M2VB 2KVKA 1C0FS 2NUPA 1T3YA 2LJ8A 1CNUA 3EGXA 1M4JA 2FH3A 3EH1A 3EGDA 5KYWB 3Q2BA 3CJCG 5KYXA 1PD0A 3CJBG 1Q8XA 5HVKB 5FAEA 1DEJS 4S10C 1RGIG 1HQZ1 5KYUB 1CFYA 2LXXA 1VFQA 4CBUG 1WFSA 1KCQA 3CIPG 3EG9A 1P8ZG 1M2VA 1ESVS 4LIZA 1SVRA 1P8XA 2FH1A 2MOTA 2HD7A 4Z94G 1NPHA 5HVKD 5IVUA 2MP4A 3FG6A 3FFNA 5KYWA 2NUTB 1NM1G 3TU5B 3A5NS 4PKGG 1H1VG 2FF6G 1D0NA 1COFA 2MV2A 3CI5G 1SVQA 2LLFA 2VILA 4PKIG 5KYUA 3FG7A 1WM4A 1V6FA 1C0GS 2FF3A 1YAGG 2VIKA 1M2OA 1YVNG 1X67A 2W0IA 2D8BA 1J72A 2FH4A 2VACA 1AHQA 2I2QA 4BEX1 2NUTA 2FH2A 1UDMA 5KYNA 3EFOB 1NLVG 5KYYB 1QPVA 4JD2H 1NMDG 1PCXA 1D4XG 1SVYA 1T2LA 3DAWB 3FFKA 1F7SA 1TVJA 4CBXG 2FGHA 1T3XA 3A5LS 2QTVA 1T44G 5L6WC 3L50A 1AK7A 1Q8GA 1WNJA 2NUPB 1PD1A 4PKHB 1TMWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3EFO A;  5A1M A;  5KYY A;  4KEE A;  3EGX B;  1MDU A;  2XFA A;  3A5M S;  4KED A;  3EGD B;  1JHW A;  3A5O S;  5KYX B;  1EQY S;  3EH2 A;  1VKK A;  2XF1 A;  1AK6 A;  5FAF A;  2L72 A;  5DD2 A;  4KEF A;  4CBW G;  3EG9 B;  1M2V B;  2KVK A;  1C0F S;  2NUP A;  1T3Y A;  2LJ8 A;  1CNU A;  3EGX A;  1M4J A;  2FH3 A;  3EH1 A;  3EGD A;  5KYW B;  3Q2B A;  3CJC G;  5KYX A;  1PD0 A;  3CJB G;  1Q8X A;  5HVK B;  5FAE A;  1DEJ S;  4S10 C;  1RGI G;  1HQZ 1;  5KYU B;  1CFY A;  2LXX A;  1VFQ A;  4CBU G;  1WFS A;  1KCQ A;  3CIP G;  3EG9 A;  1P8Z G;  1M2V A;  1ESV S;  4LIZ A;  1SVR A;  1P8X A;  2FH1 A;  2MOT A;  2HD7 A;  4Z94 G;  1NPH A;  5HVK D;  5IVU A;  2MP4 A;  3FG6 A;  3FFN A;  5KYW A;  2NUT B;  1NM1 G;  3TU5 B;  3A5N S;  4PKG G;  1H1V G;  2FF6 G;  1D0N A;  1COF A;  2MV2 A;  3CI5 G;  1SVQ A;  2LLF A;  2VIL A;  4PKI G;  5KYU A;  3FG7 A;  1WM4 A;  1V6F A;  1C0G S;  2FF3 A;  1YAG G;  2VIK A;  1M2O A;  1YVN G;  1X67 A;  2W0I A;  2D8B A;  1J72 A;  2FH4 A;  2VAC A;  1AHQ A;  2I2Q A;  4BEX 1;  2NUT A;  2FH2 A;  1UDM A;  5KYN A;  3EFO B;  1NLV G;  5KYY B;  1QPV A;  4JD2 H;  1NMD G;  1PCX A;  1D4X G;  1SVY A;  1T2L A;  3DAW B;  3FFK A;  1F7S A;  1TVJ A;  4CBX G;  2FGH A;  1T3X A;  3A5L S;  2QTV A;  1T44 G;  5L6W C;  3L50 A;  1AK7 A;  1Q8G A;  1WNJ A;  2NUP B;  1PD1 A;  4PKH B;  1TMW A; 
#chains in the Genus database with same CATH topology
 3EFO A;  5A1M A;  3DA7 A;  5KYY A;  4KEE A;  3EGX B;  1MDU A;  2XFA A;  3A5M S;  4KED A;  3EGD B;  1JHW A;  3A5O S;  5KYX B;  1EQY S;  3EH2 A;  1VKK A;  2XF1 A;  1AK6 A;  5FAF A;  2L72 A;  5DD2 A;  4KEF A;  4CBW G;  3EG9 B;  1M2V B;  2KVK A;  1C0F S;  2NUP A;  1T3Y A;  2LJ8 A;  1CNU A;  3EGX A;  1M4J A;  2FH3 A;  3EH1 A;  3EGD A;  5KYW B;  3Q2B A;  3CJC G;  5KYX A;  1PD0 A;  3CJB G;  1Q8X A;  5HVK B;  5FAE A;  1DEJ S;  4S10 C;  1RGI G;  1HQZ 1;  5KYU B;  1CFY A;  2LXX A;  1VFQ A;  4CBU G;  1WFS A;  1KCQ A;  3CIP G;  3EG9 A;  1P8Z G;  1M2V A;  1ESV S;  4LIZ A;  1SVR A;  1P8X A;  2FH1 A;  2MOT A;  2HD7 A;  4Z94 G;  1NPH A;  5HVK D;  5IVU A;  2MP4 A;  3FG6 A;  3FFN A;  5KYW A;  2NUT B;  1NM1 G;  3TU5 B;  3A5N S;  4PKG G;  1H1V G;  2FF6 G;  1D0N A;  1COF A;  2MV2 A;  3CI5 G;  1SVQ A;  2LLF A;  2VIL A;  4PKI G;  5KYU A;  3FG7 A;  1WM4 A;  1V6F A;  1C0G S;  2FF3 A;  1YAG G;  2VIK A;  1M2O A;  1YVN G;  1X67 A;  2W0I A;  2D8B A;  1J72 A;  2FH4 A;  2VAC A;  1AHQ A;  2I2Q A;  4BEX 1;  2NUT A;  2FH2 A;  1UDM A;  5KYN A;  3EFO B;  1NLV G;  5KYY B;  1QPV A;  4JD2 H;  1NMD G;  1PCX A;  1D4X G;  1SVY A;  1T2L A;  3DAW B;  3FFK A;  1F7S A;  1TVJ A;  4CBX G;  2FGH A;  1T3X A;  3A5L S;  2QTV A;  1T44 G;  5L6W C;  3L50 A;  1AK7 A;  1Q8G A;  1WNJ A;  2NUP B;  1PD1 A;  4PKH B;  1TMW A; 
#chains in the Genus database with same CATH homology
 3EFO A;  5A1M A;  3DA7 A;  5KYY A;  4KEE A;  3EGX B;  1MDU A;  2XFA A;  3A5M S;  4KED A;  3EGD B;  1JHW A;  3A5O S;  5KYX B;  1EQY S;  3EH2 A;  1VKK A;  2XF1 A;  1AK6 A;  5FAF A;  2L72 A;  5DD2 A;  4KEF A;  4CBW G;  3EG9 B;  1M2V B;  2KVK A;  1C0F S;  2NUP A;  1T3Y A;  2LJ8 A;  1CNU A;  3EGX A;  1M4J A;  2FH3 A;  3EH1 A;  3EGD A;  5KYW B;  3Q2B A;  3CJC G;  5KYX A;  1PD0 A;  3CJB G;  1Q8X A;  5HVK B;  5FAE A;  1DEJ S;  4S10 C;  1RGI G;  1HQZ 1;  5KYU B;  1CFY A;  2LXX A;  1VFQ A;  4CBU G;  1WFS A;  1KCQ A;  3CIP G;  3EG9 A;  1P8Z G;  1M2V A;  1ESV S;  4LIZ A;  1SVR A;  1P8X A;  2FH1 A;  2MOT A;  2HD7 A;  4Z94 G;  1NPH A;  5HVK D;  5IVU A;  2MP4 A;  3FG6 A;  3FFN A;  5KYW A;  2NUT B;  1NM1 G;  3TU5 B;  3A5N S;  4PKG G;  1H1V G;  2FF6 G;  1D0N A;  1COF A;  2MV2 A;  3CI5 G;  1SVQ A;  2LLF A;  2VIL A;  4PKI G;  5KYU A;  3FG7 A;  1WM4 A;  1V6F A;  1C0G S;  2FF3 A;  1YAG G;  2VIK A;  1M2O A;  1YVN G;  1X67 A;  2W0I A;  2D8B A;  1J72 A;  2FH4 A;  2VAC A;  1AHQ A;  2I2Q A;  4BEX 1;  2NUT A;  2FH2 A;  1UDM A;  5KYN A;  3EFO B;  1NLV G;  5KYY B;  1QPV A;  4JD2 H;  1NMD G;  1PCX A;  1D4X G;  1SVY A;  1T2L A;  3DAW B;  3FFK A;  1F7S A;  1TVJ A;  4CBX G;  2FGH A;  1T3X A;  3A5L S;  2QTV A;  1T44 G;  5L6W C;  3L50 A;  1AK7 A;  1Q8G A;  1WNJ A;  2NUP B;  1PD1 A;  4PKH B;  1TMW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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