1QPVA

Yeast cofilin
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
133
structure length
133
Chain Sequence
VAVADESLTAFNDLKLGKKYKFILFGLNDAKTEIVVKETSTDPSYDAFLEKLPENDCLYAIYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSTDVQGTDFSEVSYDSVLERVSR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure determination of yeast cofilin.
pubmed doi rcsb
molecule tags Actin-binding protein
source organism Saccharomyces cerevisiae
molecule keywords YEAST COFILIN
total genus 26
structure length 133
sequence length 133
ec nomenclature
pdb deposition date 1999-05-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00241 Cofilin_ADF Cofilin/tropomyosin-type actin-binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 1qpvA00
2VACA 1SVYA 1NMDG 1MDUA 2MV2A 4JD2H 4PKIG 3L50A 1Q8XA 1YVNG 1EQYS 1F7SA 1NPHA 3EG9A 5KYUB 1AHQA 3EG9B 5HVKB 3FG7A 1T3XA 2LJ8A 1COFA 1YAGG 2FF3A 1ESVS 2L72A 3EGDB 2W0IA 1D4XG 1UDMA 2D8BA 4KEFA 1WM4A 2FH1A 1WNJA 1M2VA 1CFYA 3DAWB 5KYWA 1M2VB 1X67A 4LIZA 1VKKA 5KYWB 5HVKD 1C0GS 3A5LS 5KYXA 5FAEA 1PD0A 3FG6A 3A5OS 4CBWG 3EFOB 5KYNA 5KYXB 2I2QA 1AK7A 1D0NA 4KEEA 5KYUA 2FH4A 1SVQA 3FFNA 1T44G 1KCQA 2KVKA 3EGDA 1CNUA 1JHWA 5KYYB 1QPVA 1J72A 1P8ZG 2NUPB 3CI5G 3Q2BA 3EH1A 3FFKA 1NLVG 2FH2A 4Z94G 2HD7A 2LLFA 4S10C 5FAFA 3CIPG 2FGHA 3CJCG 2VILA 2QTVA 4CBUG 3EFOA 1NM1G 1H1VG 2XF1A 1T3YA 1P8XA 4CBXG 1C0FS 1T2LA 1V6FA 1WFSA 2FF6G 3EH2A 1TVJA 5KYYA 2FH3A 3TU5B 2VIKA 2MP4A 2NUPA 5DD2A 4BEX1 1M4JA 5A1MA 4PKGG 3A5NS 1PD1A 1AK6A 5L6WC 2LXXA 1DEJS 4PKHB 3EGXA 1HQZ1 4KEDA 3CJBG 3EGXB 1RGIG 5IVUA 1PCXA 1Q8GA 1VFQA 2XFAA 3A5MS 1M2OA 2NUTA 1SVRA 2MOTA 2NUTB 1TMWA
chains in the Genus database with same CATH superfamily
2VACA 1SVYA 1NMDG 1MDUA 2MV2A 4JD2H 4PKIG 3L50A 1Q8XA 1YVNG 1EQYS 1F7SA 1NPHA 3EG9A 5KYUB 1AHQA 3EG9B 5HVKB 3FG7A 1T3XA 2LJ8A 1COFA 1YAGG 2FF3A 1ESVS 2L72A 3EGDB 2W0IA 1D4XG 1UDMA 2D8BA 4KEFA 1WM4A 2FH1A 1WNJA 1M2VA 1CFYA 3DAWB 5KYWA 1M2VB 1X67A 4LIZA 1VKKA 5KYWB 5HVKD 1C0GS 3A5LS 5KYXA 5FAEA 1PD0A 3FG6A 3A5OS 4CBWG 3EFOB 5KYNA 5KYXB 2I2QA 3DA7A 1AK7A 1D0NA 4KEEA 5KYUA 2FH4A 1SVQA 3FFNA 1T44G 1KCQA 2KVKA 3EGDA 1CNUA 1JHWA 5KYYB 1QPVA 1J72A 1P8ZG 2NUPB 3CI5G 3Q2BA 3EH1A 3FFKA 1NLVG 2FH2A 4Z94G 2HD7A 2LLFA 4S10C 5FAFA 3CIPG 2FGHA 3CJCG 2VILA 2QTVA 4CBUG 3EFOA 1NM1G 1H1VG 2XF1A 1T3YA 1P8XA 4CBXG 1C0FS 1T2LA 1V6FA 1WFSA 2FF6G 3EH2A 1TVJA 5KYYA 2FH3A 3TU5B 2VIKA 2MP4A 2NUPA 5DD2A 4BEX1 1M4JA 5A1MA 4PKGG 3A5NS 1PD1A 1AK6A 5L6WC 2LXXA 1DEJS 4PKHB 3EGXA 1HQZ1 4KEDA 3CJBG 3EGXB 1RGIG 5IVUA 1PCXA 1Q8GA 1VFQA 2XFAA 3A5MS 1M2OA 2NUTA 1SVRA 2MOTA 2NUTB 1TMWA
chains in the Genus database with same CATH topology
2VACA 1SVYA 1NMDG 1MDUA 2MV2A 4JD2H 4PKIG 3L50A 1Q8XA 1YVNG 1EQYS 1F7SA 1NPHA 3EG9A 5KYUB 1AHQA 3EG9B 5HVKB 3FG7A 1T3XA 2LJ8A 1COFA 1YAGG 2FF3A 1ESVS 2L72A 3EGDB 2W0IA 1D4XG 1UDMA 2D8BA 4KEFA 1WM4A 2FH1A 1WNJA 1M2VA 1CFYA 3DAWB 5KYWA 1M2VB 1X67A 4LIZA 1VKKA 5KYWB 5HVKD 1C0GS 3A5LS 5KYXA 5FAEA 1PD0A 3FG6A 3A5OS 4CBWG 3EFOB 5KYNA 5KYXB 2I2QA 3DA7A 1AK7A 1D0NA 4KEEA 5KYUA 2FH4A 1SVQA 3FFNA 1T44G 1KCQA 2KVKA 3EGDA 1CNUA 1JHWA 5KYYB 1QPVA 1J72A 1P8ZG 2NUPB 3CI5G 3Q2BA 3EH1A 3FFKA 1NLVG 2FH2A 4Z94G 2HD7A 2LLFA 4S10C 5FAFA 3CIPG 2FGHA 3CJCG 2VILA 2QTVA 4CBUG 3EFOA 1NM1G 1H1VG 2XF1A 1T3YA 1P8XA 4CBXG 1C0FS 1T2LA 1V6FA 1WFSA 2FF6G 3EH2A 1TVJA 5KYYA 2FH3A 3TU5B 2VIKA 2MP4A 2NUPA 5DD2A 4BEX1 1M4JA 5A1MA 4PKGG 3A5NS 1PD1A 1AK6A 5L6WC 2LXXA 1DEJS 4PKHB 3EGXA 1HQZ1 4KEDA 3CJBG 3EGXB 1RGIG 5IVUA 1PCXA 1Q8GA 1VFQA 2XFAA 3A5MS 1M2OA 2NUTA 1SVRA 2MOTA 2NUTB 1TMWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2VAC A;  1SVY A;  1NMD G;  1MDU A;  2MV2 A;  4JD2 H;  4PKI G;  3L50 A;  1Q8X A;  1YVN G;  1EQY S;  1F7S A;  1NPH A;  3EG9 A;  5KYU B;  1AHQ A;  3EG9 B;  5HVK B;  3FG7 A;  1T3X A;  2LJ8 A;  1COF A;  1YAG G;  2FF3 A;  1ESV S;  2L72 A;  3EGD B;  2W0I A;  1D4X G;  1UDM A;  2D8B A;  4KEF A;  1WM4 A;  2FH1 A;  1WNJ A;  1M2V A;  1CFY A;  3DAW B;  5KYW A;  1M2V B;  1X67 A;  4LIZ A;  1VKK A;  5KYW B;  5HVK D;  1C0G S;  3A5L S;  5KYX A;  5FAE A;  1PD0 A;  3FG6 A;  3A5O S;  4CBW G;  3EFO B;  5KYN A;  5KYX B;  2I2Q A;  1AK7 A;  1D0N A;  4KEE A;  5KYU A;  2FH4 A;  1SVQ A;  3FFN A;  1T44 G;  1KCQ A;  2KVK A;  3EGD A;  1CNU A;  1JHW A;  5KYY B;  1QPV A;  1J72 A;  1P8Z G;  2NUP B;  3CI5 G;  3Q2B A;  3EH1 A;  3FFK A;  1NLV G;  2FH2 A;  4Z94 G;  2HD7 A;  2LLF A;  4S10 C;  5FAF A;  3CIP G;  2FGH A;  3CJC G;  2VIL A;  2QTV A;  4CBU G;  3EFO A;  1NM1 G;  1H1V G;  2XF1 A;  1T3Y A;  1P8X A;  4CBX G;  1C0F S;  1T2L A;  1V6F A;  1WFS A;  2FF6 G;  3EH2 A;  1TVJ A;  5KYY A;  2FH3 A;  3TU5 B;  2VIK A;  2MP4 A;  2NUP A;  5DD2 A;  4BEX 1;  1M4J A;  5A1M A;  4PKG G;  3A5N S;  1PD1 A;  1AK6 A;  5L6W C;  2LXX A;  1DEJ S;  4PKH B;  3EGX A;  1HQZ 1;  4KED A;  3CJB G;  3EGX B;  1RGI G;  5IVU A;  1PCX A;  1Q8G A;  1VFQ A;  2XFA A;  3A5M S;  1M2O A;  2NUT A;  1SVR A;  2MOT A;  2NUT B;  1TMW A; 
#chains in the Genus database with same CATH topology
 2VAC A;  1SVY A;  1NMD G;  1MDU A;  2MV2 A;  4JD2 H;  4PKI G;  3L50 A;  1Q8X A;  1YVN G;  1EQY S;  1F7S A;  1NPH A;  3EG9 A;  5KYU B;  1AHQ A;  3EG9 B;  5HVK B;  3FG7 A;  1T3X A;  2LJ8 A;  1COF A;  1YAG G;  2FF3 A;  1ESV S;  2L72 A;  3EGD B;  2W0I A;  1D4X G;  1UDM A;  2D8B A;  4KEF A;  1WM4 A;  2FH1 A;  1WNJ A;  1M2V A;  1CFY A;  3DAW B;  5KYW A;  1M2V B;  1X67 A;  4LIZ A;  1VKK A;  5KYW B;  5HVK D;  1C0G S;  3A5L S;  5KYX A;  5FAE A;  1PD0 A;  3FG6 A;  3A5O S;  4CBW G;  3EFO B;  5KYN A;  5KYX B;  2I2Q A;  3DA7 A;  1AK7 A;  1D0N A;  4KEE A;  5KYU A;  2FH4 A;  1SVQ A;  3FFN A;  1T44 G;  1KCQ A;  2KVK A;  3EGD A;  1CNU A;  1JHW A;  5KYY B;  1QPV A;  1J72 A;  1P8Z G;  2NUP B;  3CI5 G;  3Q2B A;  3EH1 A;  3FFK A;  1NLV G;  2FH2 A;  4Z94 G;  2HD7 A;  2LLF A;  4S10 C;  5FAF A;  3CIP G;  2FGH A;  3CJC G;  2VIL A;  2QTV A;  4CBU G;  3EFO A;  1NM1 G;  1H1V G;  2XF1 A;  1T3Y A;  1P8X A;  4CBX G;  1C0F S;  1T2L A;  1V6F A;  1WFS A;  2FF6 G;  3EH2 A;  1TVJ A;  5KYY A;  2FH3 A;  3TU5 B;  2VIK A;  2MP4 A;  2NUP A;  5DD2 A;  4BEX 1;  1M4J A;  5A1M A;  4PKG G;  3A5N S;  1PD1 A;  1AK6 A;  5L6W C;  2LXX A;  1DEJ S;  4PKH B;  3EGX A;  1HQZ 1;  4KED A;  3CJB G;  3EGX B;  1RGI G;  5IVU A;  1PCX A;  1Q8G A;  1VFQ A;  2XFA A;  3A5M S;  1M2O A;  2NUT A;  1SVR A;  2MOT A;  2NUT B;  1TMW A; 
#chains in the Genus database with same CATH homology
 2VAC A;  1SVY A;  1NMD G;  1MDU A;  2MV2 A;  4JD2 H;  4PKI G;  3L50 A;  1Q8X A;  1YVN G;  1EQY S;  1F7S A;  1NPH A;  3EG9 A;  5KYU B;  1AHQ A;  3EG9 B;  5HVK B;  3FG7 A;  1T3X A;  2LJ8 A;  1COF A;  1YAG G;  2FF3 A;  1ESV S;  2L72 A;  3EGD B;  2W0I A;  1D4X G;  1UDM A;  2D8B A;  4KEF A;  1WM4 A;  2FH1 A;  1WNJ A;  1M2V A;  1CFY A;  3DAW B;  5KYW A;  1M2V B;  1X67 A;  4LIZ A;  1VKK A;  5KYW B;  5HVK D;  1C0G S;  3A5L S;  5KYX A;  5FAE A;  1PD0 A;  3FG6 A;  3A5O S;  4CBW G;  3EFO B;  5KYN A;  5KYX B;  2I2Q A;  3DA7 A;  1AK7 A;  1D0N A;  4KEE A;  5KYU A;  2FH4 A;  1SVQ A;  3FFN A;  1T44 G;  1KCQ A;  2KVK A;  3EGD A;  1CNU A;  1JHW A;  5KYY B;  1QPV A;  1J72 A;  1P8Z G;  2NUP B;  3CI5 G;  3Q2B A;  3EH1 A;  3FFK A;  1NLV G;  2FH2 A;  4Z94 G;  2HD7 A;  2LLF A;  4S10 C;  5FAF A;  3CIP G;  2FGH A;  3CJC G;  2VIL A;  2QTV A;  4CBU G;  3EFO A;  1NM1 G;  1H1V G;  2XF1 A;  1T3Y A;  1P8X A;  4CBX G;  1C0F S;  1T2L A;  1V6F A;  1WFS A;  2FF6 G;  3EH2 A;  1TVJ A;  5KYY A;  2FH3 A;  3TU5 B;  2VIK A;  2MP4 A;  2NUP A;  5DD2 A;  4BEX 1;  1M4J A;  5A1M A;  4PKG G;  3A5N S;  1PD1 A;  1AK6 A;  5L6W C;  2LXX A;  1DEJ S;  4PKH B;  3EGX A;  1HQZ 1;  4KED A;  3CJB G;  3EGX B;  1RGI G;  5IVU A;  1PCX A;  1Q8G A;  1VFQ A;  2XFA A;  3A5M S;  1M2O A;  2NUT A;  1SVR A;  2MOT A;  2NUT B;  1TMW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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