1RGI | Genus

Total Genus 101

Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	101
sequence length	346
structure length	346
Chain Sequence	VVEHPEFLKAGKEPGLQIWRVEKFDLVPVPPNLYGDFFTGDAYVILKTVQLRNGILQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGFKHVVPNEVVVQRLLQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIYQWCGSKSNRFERLKATQVSKGIRDNERSGRAQVSVFEEGAEPEAMLQVLGPKPTLPEATEDTVKEDAANRKLAKLYKVSNGAGPMVVSLVADENPFAQGALRSEDCFILDHGKDGKIFVWKGKQANMEERKAALKTASDFISKMDYPKQTQVSVLPEGGETPLFRQFFKNWRD

Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

loadScript /static/js/j2s/core/package.js

loadScript /static/js/j2s/core/corejmol.z.js

loadScript /static/js/j2s/core/corescript.z.js

JSmol exec jmolApplet0 start applet null

Jmol JavaScript applet jmolApplet0__326399923424744__ initializing

Jmol getValue debug null

Jmol getValue logLevel null

Jmol getValue allowjavascript null

AppletRegistry.checkIn(jmolApplet0__326399923424744__)

vwrOptions:

{ "name":"jmolApplet0","applet":true,"documentBase":"https://genus.fuw.edu.pl/view/1RGI/G/","platform":"J.awtjs2d.Platform","fullName":"jmolApplet0__326399923424744__","codePath":"https:/static/js/j2s/","display":"jmolApplet0_canvas2d","signedApplet":"true","appletReadyCallback":"Jmol._readyCallback","statusListener":"[J.appletjs.Jmol object]","syncId":"326399923424744","bgcolor":"white" }

setting document base to "https://genus.fuw.edu.pl/view/1RGI/G/"

Jmol Version: 14.29.13 2018-04-17 17:17

java.vendor: Java2Script (HTML5)

java.version: 2018-01-28 23:38:52 (JSmol/j2s)

os.name: Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)

Access: ALL

memory: 0.0/0.0

processors available: 1

useCommandThread: false

appletId:jmolApplet0 (signed)

Jmol getValue emulate null

defaults = "Jmol"

Jmol getValue boxbgcolor null

Jmol getValue bgcolor white

backgroundColor = "white"

Jmol getValue ANIMFRAMECallback null

Jmol getValue APPLETREADYCallback Jmol._readyCallback

APPLETREADYCallback = "Jmol._readyCallback"

callback set for APPLETREADYCallback Jmol._readyCallback APPLETREADY

Jmol getValue ATOMMOVEDCallback null

Jmol getValue AUDIOCallback null

Jmol getValue CLICKCallback null

Jmol getValue DRAGDROPCallback null

Jmol getValue ECHOCallback null

Jmol getValue ERRORCallback null

Jmol getValue EVALCallback null

Jmol getValue HOVERCallback null

Jmol getValue IMAGECallback null

Jmol getValue LOADSTRUCTCallback null

Jmol getValue MEASURECallback null

Jmol getValue MESSAGECallback null

Jmol getValue MINIMIZATIONCallback null

Jmol getValue SERVICECallback null

Jmol getValue PICKCallback null

Jmol getValue RESIZECallback null

Jmol getValue SCRIPTCallback null

Jmol getValue SYNCCallback null

Jmol getValue STRUCTUREMODIFIEDCallback null

Jmol getValue doTranslate null

language=en_US

Jmol getValue popupMenu null

Jmol getValue script null

Jmol getValue loadInline null

Jmol getValue load null

Jmol applet jmolApplet0__326399923424744__ ready

script 1 started

platformSpeed = 8

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	Structure of the N-terminal half of gelsolin bound to actin: roles in severing, apoptosis and FAF pubmed doi rcsb
molecule keywords	Gelsolin
molecule tags	Contractile protein
total genus	101
structure length	346
sequence length	346
ec nomenclature
pdb deposition date	2003-11-12

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
G	PF00626	Gelsolin	Gelsolin repeat

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.40.20.10	Alpha Beta	3-Layer(aba) Sandwich	Severin	Severin	1rgiG02
3.40.20.10	Alpha Beta	3-Layer(aba) Sandwich	Severin	Severin	1rgiG01
3.40.20.10	Alpha Beta	3-Layer(aba) Sandwich	Severin	Severin	1rgiG03

2FH4A 5FAEA 2W0IA 1M4JA 5HVKB 1QPVA 2LJ8A 1F7SA 1PCXA 2L72A 4KEDA 5KYYB 2MP4A 1NLVG 4CBWG 5FAFA 1P8XA 3EFOB 3CJCG 3EGXB 1YVNG 3EG9B 1D0NA 5KYYA 1RGIG 1PD0A 1HQZ1 5A1MA 4CBXG 3EFOA 1NPHA 3EGXA 3FG7A 3L50A 3EG9A 3EGDB 4CBUG 2XFAA 1H1VG 3CIPG 2FF3A 4S10C 1UDMA 5KYNA 1SVRA 1T2LA 3EGDA 3FG6A 4BEX1 2VACA 3A5OS 1KCQA 1WFSA 2FH2A 5IVUA 1DEJS 1MDUA 1CFYA 1SVYA 1YAGG 1TVJA 2FF6G 3EH1A 4KEFA 1T3XA 4PKIG 3CI5G 5HVKD 1C0GS 1Q8XA 3Q2BA 4KEEA 1C0FS 5DD2A 3TU5B 1AK6A 4JD2H 1ESVS 1X67A 2I2QA 2LXXA 1M2VB 4PKGG 1NMDG 5L6WC 2NUTB 5KYXB 3A5NS 2FH3A 1T44G 1Q8GA 1PD1A 2NUPA 1M2VA 1EQYS 2VILA 2FGHA 2HD7A 1P8ZG 2NUTA 5KYXA 3A5MS 1WM4A 3EH2A 2KVKA 1WNJA 1TMWA 4Z94G 1VKKA 2D8BA 2MOTA 1SVQA 5KYWB 2VIKA 1AHQA 3A5LS 2FH1A 2MV2A 1AK7A 1T3YA 5KYWA 2NUPB 3FFNA 3CJBG 1D4XG 1VFQA 4PKHB 2LLFA 2QTVA 3DAWB 1M2OA 1J72A 5KYUB 2XF1A 1V6FA 1JHWA 5KYUA 1CNUA 4LIZA 1NM1G 3FFKA 1COFA
chains in the Genus database with same CATH superfamily

2FH4A 5FAEA 2W0IA 1M4JA 5HVKB 1QPVA 2LJ8A 1F7SA 1PCXA 2L72A 4KEDA 5KYYB 2MP4A 1NLVG 4CBWG 5FAFA 1P8XA 3EFOB 3CJCG 3EGXB 1YVNG 3EG9B 1D0NA 5KYYA 1RGIG 1PD0A 1HQZ1 5A1MA 4CBXG 3EFOA 1NPHA 3EGXA 3FG7A 3L50A 3EG9A 3EGDB 4CBUG 2XFAA 1H1VG 3CIPG 2FF3A 4S10C 1UDMA 3DA7A 5KYNA 1SVRA 1T2LA 3EGDA 3FG6A 4BEX1 2VACA 3A5OS 1KCQA 1WFSA 2FH2A 5IVUA 1DEJS 1MDUA 1CFYA 1SVYA 1YAGG 1TVJA 2FF6G 3EH1A 4KEFA 1T3XA 4PKIG 3CI5G 5HVKD 1C0GS 1Q8XA 3Q2BA 4KEEA 1C0FS 5DD2A 3TU5B 1AK6A 4JD2H 1ESVS 1X67A 2I2QA 2LXXA 1M2VB 4PKGG 1NMDG 5L6WC 2NUTB 5KYXB 3A5NS 2FH3A 1T44G 1Q8GA 1PD1A 2NUPA 1M2VA 1EQYS 2VILA 2FGHA 2HD7A 1P8ZG 2NUTA 5KYXA 3A5MS 1WM4A 3EH2A 2KVKA 1WNJA 1TMWA 4Z94G 1VKKA 2D8BA 2MOTA 1SVQA 5KYWB 2VIKA 1AHQA 3A5LS 2FH1A 2MV2A 1AK7A 1T3YA 5KYWA 2NUPB 3FFNA 3CJBG 1D4XG 1VFQA 4PKHB 2LLFA 2QTVA 3DAWB 1M2OA 1J72A 5KYUB 2XF1A 1V6FA 1JHWA 5KYUA 1CNUA 4LIZA 1NM1G 3FFKA 1COFA
chains in the Genus database with same CATH topology

2FH4A 5FAEA 2W0IA 1M4JA 5HVKB 1QPVA 2LJ8A 1F7SA 1PCXA 2L72A 4KEDA 5KYYB 2MP4A 1NLVG 4CBWG 5FAFA 1P8XA 3EFOB 3CJCG 3EGXB 1YVNG 3EG9B 1D0NA 5KYYA 1RGIG 1PD0A 1HQZ1 5A1MA 4CBXG 3EFOA 1NPHA 3EGXA 3FG7A 3L50A 3EG9A 3EGDB 4CBUG 2XFAA 1H1VG 3CIPG 2FF3A 4S10C 1UDMA 3DA7A 5KYNA 1SVRA 1T2LA 3EGDA 3FG6A 4BEX1 2VACA 3A5OS 1KCQA 1WFSA 2FH2A 5IVUA 1DEJS 1MDUA 1CFYA 1SVYA 1YAGG 1TVJA 2FF6G 3EH1A 4KEFA 1T3XA 4PKIG 3CI5G 5HVKD 1C0GS 1Q8XA 3Q2BA 4KEEA 1C0FS 5DD2A 3TU5B 1AK6A 4JD2H 1ESVS 1X67A 2I2QA 2LXXA 1M2VB 4PKGG 1NMDG 5L6WC 2NUTB 5KYXB 3A5NS 2FH3A 1T44G 1Q8GA 1PD1A 2NUPA 1M2VA 1EQYS 2VILA 2FGHA 2HD7A 1P8ZG 2NUTA 5KYXA 3A5MS 1WM4A 3EH2A 2KVKA 1WNJA 1TMWA 4Z94G 1VKKA 2D8BA 2MOTA 1SVQA 5KYWB 2VIKA 1AHQA 3A5LS 2FH1A 2MV2A 1AK7A 1T3YA 5KYWA 2NUPB 3FFNA 3CJBG 1D4XG 1VFQA 4PKHB 2LLFA 2QTVA 3DAWB 1M2OA 1J72A 5KYUB 2XF1A 1V6FA 1JHWA 5KYUA 1CNUA 4LIZA 1NM1G 3FFKA 1COFA
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 2FH4 A;  5FAE A;  2W0I A;  1M4J A;  5HVK B;  1QPV A;  2LJ8 A;  1F7S A;  1PCX A;  2L72 A;  4KED A;  5KYY B;  2MP4 A;  1NLV G;  4CBW G;  5FAF A;  1P8X A;  3EFO B;  3CJC G;  3EGX B;  1YVN G;  3EG9 B;  1D0N A;  5KYY A;  1RGI G;  1PD0 A;  1HQZ 1;  5A1M A;  4CBX G;  3EFO A;  1NPH A;  3EGX A;  3FG7 A;  3L50 A;  3EG9 A;  3EGD B;  4CBU G;  2XFA A;  1H1V G;  3CIP G;  2FF3 A;  4S10 C;  1UDM A;  5KYN A;  1SVR A;  1T2L A;  3EGD A;  3FG6 A;  4BEX 1;  2VAC A;  3A5O S;  1KCQ A;  1WFS A;  2FH2 A;  5IVU A;  1DEJ S;  1MDU A;  1CFY A;  1SVY A;  1YAG G;  1TVJ A;  2FF6 G;  3EH1 A;  4KEF A;  1T3X A;  4PKI G;  3CI5 G;  5HVK D;  1C0G S;  1Q8X A;  3Q2B A;  4KEE A;  1C0F S;  5DD2 A;  3TU5 B;  1AK6 A;  4JD2 H;  1ESV S;  1X67 A;  2I2Q A;  2LXX A;  1M2V B;  4PKG G;  1NMD G;  5L6W C;  2NUT B;  5KYX B;  3A5N S;  2FH3 A;  1T44 G;  1Q8G A;  1PD1 A;  2NUP A;  1M2V A;  1EQY S;  2VIL A;  2FGH A;  2HD7 A;  1P8Z G;  2NUT A;  5KYX A;  3A5M S;  1WM4 A;  3EH2 A;  2KVK A;  1WNJ A;  1TMW A;  4Z94 G;  1VKK A;  2D8B A;  2MOT A;  1SVQ A;  5KYW B;  2VIK A;  1AHQ A;  3A5L S;  2FH1 A;  2MV2 A;  1AK7 A;  1T3Y A;  5KYW A;  2NUP B;  3FFN A;  3CJB G;  1D4X G;  1VFQ A;  4PKH B;  2LLF A;  2QTV A;  3DAW B;  1M2O A;  1J72 A;  5KYU B;  2XF1 A;  1V6F A;  1JHW A;  5KYU A;  1CNU A;  4LIZ A;  1NM1 G;  3FFK A;  1COF A; 
#chains in the Genus database with same CATH topology
 2FH4 A;  5FAE A;  2W0I A;  1M4J A;  5HVK B;  1QPV A;  2LJ8 A;  1F7S A;  1PCX A;  2L72 A;  4KED A;  5KYY B;  2MP4 A;  1NLV G;  4CBW G;  5FAF A;  1P8X A;  3EFO B;  3CJC G;  3EGX B;  1YVN G;  3EG9 B;  1D0N A;  5KYY A;  1RGI G;  1PD0 A;  1HQZ 1;  5A1M A;  4CBX G;  3EFO A;  1NPH A;  3EGX A;  3FG7 A;  3L50 A;  3EG9 A;  3EGD B;  4CBU G;  2XFA A;  1H1V G;  3CIP G;  2FF3 A;  4S10 C;  1UDM A;  3DA7 A;  5KYN A;  1SVR A;  1T2L A;  3EGD A;  3FG6 A;  4BEX 1;  2VAC A;  3A5O S;  1KCQ A;  1WFS A;  2FH2 A;  5IVU A;  1DEJ S;  1MDU A;  1CFY A;  1SVY A;  1YAG G;  1TVJ A;  2FF6 G;  3EH1 A;  4KEF A;  1T3X A;  4PKI G;  3CI5 G;  5HVK D;  1C0G S;  1Q8X A;  3Q2B A;  4KEE A;  1C0F S;  5DD2 A;  3TU5 B;  1AK6 A;  4JD2 H;  1ESV S;  1X67 A;  2I2Q A;  2LXX A;  1M2V B;  4PKG G;  1NMD G;  5L6W C;  2NUT B;  5KYX B;  3A5N S;  2FH3 A;  1T44 G;  1Q8G A;  1PD1 A;  2NUP A;  1M2V A;  1EQY S;  2VIL A;  2FGH A;  2HD7 A;  1P8Z G;  2NUT A;  5KYX A;  3A5M S;  1WM4 A;  3EH2 A;  2KVK A;  1WNJ A;  1TMW A;  4Z94 G;  1VKK A;  2D8B A;  2MOT A;  1SVQ A;  5KYW B;  2VIK A;  1AHQ A;  3A5L S;  2FH1 A;  2MV2 A;  1AK7 A;  1T3Y A;  5KYW A;  2NUP B;  3FFN A;  3CJB G;  1D4X G;  1VFQ A;  4PKH B;  2LLF A;  2QTV A;  3DAW B;  1M2O A;  1J72 A;  5KYU B;  2XF1 A;  1V6F A;  1JHW A;  5KYU A;  1CNU A;  4LIZ A;  1NM1 G;  3FFK A;  1COF A; 
#chains in the Genus database with same CATH homology
 2FH4 A;  5FAE A;  2W0I A;  1M4J A;  5HVK B;  1QPV A;  2LJ8 A;  1F7S A;  1PCX A;  2L72 A;  4KED A;  5KYY B;  2MP4 A;  1NLV G;  4CBW G;  5FAF A;  1P8X A;  3EFO B;  3CJC G;  3EGX B;  1YVN G;  3EG9 B;  1D0N A;  5KYY A;  1RGI G;  1PD0 A;  1HQZ 1;  5A1M A;  4CBX G;  3EFO A;  1NPH A;  3EGX A;  3FG7 A;  3L50 A;  3EG9 A;  3EGD B;  4CBU G;  2XFA A;  1H1V G;  3CIP G;  2FF3 A;  4S10 C;  1UDM A;  3DA7 A;  5KYN A;  1SVR A;  1T2L A;  3EGD A;  3FG6 A;  4BEX 1;  2VAC A;  3A5O S;  1KCQ A;  1WFS A;  2FH2 A;  5IVU A;  1DEJ S;  1MDU A;  1CFY A;  1SVY A;  1YAG G;  1TVJ A;  2FF6 G;  3EH1 A;  4KEF A;  1T3X A;  4PKI G;  3CI5 G;  5HVK D;  1C0G S;  1Q8X A;  3Q2B A;  4KEE A;  1C0F S;  5DD2 A;  3TU5 B;  1AK6 A;  4JD2 H;  1ESV S;  1X67 A;  2I2Q A;  2LXX A;  1M2V B;  4PKG G;  1NMD G;  5L6W C;  2NUT B;  5KYX B;  3A5N S;  2FH3 A;  1T44 G;  1Q8G A;  1PD1 A;  2NUP A;  1M2V A;  1EQY S;  2VIL A;  2FGH A;  2HD7 A;  1P8Z G;  2NUT A;  5KYX A;  3A5M S;  1WM4 A;  3EH2 A;  2KVK A;  1WNJ A;  1TMW A;  4Z94 G;  1VKK A;  2D8B A;  2MOT A;  1SVQ A;  5KYW B;  2VIK A;  1AHQ A;  3A5L S;  2FH1 A;  2MV2 A;  1AK7 A;  1T3Y A;  5KYW A;  2NUP B;  3FFN A;  3CJB G;  1D4X G;  1VFQ A;  4PKH B;  2LLF A;  2QTV A;  3DAW B;  1M2O A;  1J72 A;  5KYU B;  2XF1 A;  1V6F A;  1JHW A;  5KYU A;  1CNU A;  4LIZ A;  1NM1 G;  3FFK A;  1COF A;

...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)

...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...

1RGIG

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations