1SVQA

Structure of severin domain 2 in solution
Total Genus 17
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
17
sequence length
94
structure length
94
Chain Sequence
EYKPRLLHISGDKNAKVAEVPLATSSLNSGDCFLLDAGLTIYQFNGSKSSPQEKNKAAEVARAIDAERKGLPKVEVFCETDSDIPAEFWKLLGG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of severin domain 2 in solution.
pubmed doi rcsb
molecule tags Actin-binding
source organism Dictyostelium discoideum
molecule keywords SEVERIN
total genus 17
structure length 94
sequence length 94
ec nomenclature
pdb deposition date 1994-10-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00626 Gelsolin Gelsolin repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 1svqA00
3EG9A 2NUTA 2NUPA 1T3YA 1J72A 1CNUA 2FF6G 2VACA 3EFOB 2FH2A 2D8BA 1M2VB 3CJCG 1F7SA 3FG7A 1Q8XA 4KEDA 1M4JA 1WNJA 1YVNG 1AK7A 5KYWB 5KYXB 4LIZA 4CBWG 1COFA 2QTVA 1HQZ1 2FH4A 1UDMA 1AK6A 3EFOA 1M2VA 4PKHB 1VKKA 3DAWB 1PD1A 3FFKA 3FFNA 4CBUG 2I2QA 1RGIG 3A5MS 3CIPG 1P8ZG 1ESVS 2XF1A 4JD2H 2VILA 4KEFA 5HVKB 5KYWA 1WFSA 5KYXA 1X67A 1SVQA 1DEJS 3CJBG 3FG6A 5KYYB 1C0GS 3A5LS 1NLVG 4CBXG 1PD0A 2FF3A 2XFAA 3TU5B 1V6FA 5KYNA 1T44G 1Q8GA 1YAGG 5KYUB 1T2LA 1D4XG 5KYYA 2VIKA 3EH1A 5FAEA 5A1MA 3EGXB 1P8XA 1D0NA 3A5OS 2LLFA 1WM4A 1PCXA 1NM1G 2W0IA 1NPHA 5KYUA 2LJ8A 5IVUA 1MDUA 3L50A 5HVKD 4Z94G 5DD2A 1JHWA 4PKGG 3EGXA 1EQYS 1H1VG 1VFQA 2KVKA 3A5NS 1TMWA 2FH3A 4KEEA 1QPVA 5FAFA 3EH2A 1NMDG 3EGDB 2FGHA 2MOTA 2L72A 1M2OA 2FH1A 4BEX1 2MP4A 3Q2BA 1TVJA 1T3XA 3EG9B 2NUTB 2NUPB 4PKIG 3CI5G 2HD7A 2MV2A 3EGDA 1CFYA 2LXXA 1C0FS 1SVRA 4S10C 5L6WC 1KCQA 1AHQA 1SVYA
chains in the Genus database with same CATH superfamily
3EG9A 2NUTA 2NUPA 1T3YA 1J72A 1CNUA 2FF6G 2VACA 3EFOB 2FH2A 2D8BA 1M2VB 3CJCG 1F7SA 3FG7A 1Q8XA 4KEDA 1M4JA 1WNJA 1YVNG 1AK7A 5KYWB 5KYXB 4LIZA 4CBWG 1COFA 2QTVA 1HQZ1 2FH4A 1UDMA 1AK6A 3EFOA 1M2VA 4PKHB 1VKKA 3DAWB 1PD1A 3FFKA 3FFNA 4CBUG 2I2QA 1RGIG 3A5MS 3CIPG 1P8ZG 1ESVS 2XF1A 4JD2H 2VILA 4KEFA 5HVKB 5KYWA 1WFSA 3DA7A 5KYXA 1X67A 1SVQA 1DEJS 3CJBG 3FG6A 5KYYB 1C0GS 3A5LS 1NLVG 4CBXG 1PD0A 2FF3A 2XFAA 3TU5B 1V6FA 5KYNA 1T44G 1Q8GA 1YAGG 5KYUB 1T2LA 1D4XG 5KYYA 2VIKA 3EH1A 5FAEA 5A1MA 3EGXB 1P8XA 1D0NA 3A5OS 2LLFA 1WM4A 1PCXA 1NM1G 2W0IA 1NPHA 5KYUA 2LJ8A 5IVUA 1MDUA 3L50A 5HVKD 4Z94G 5DD2A 1JHWA 4PKGG 3EGXA 1EQYS 1H1VG 1VFQA 2KVKA 3A5NS 1TMWA 2FH3A 4KEEA 1QPVA 5FAFA 3EH2A 1NMDG 3EGDB 2FGHA 2MOTA 2L72A 1M2OA 2FH1A 4BEX1 2MP4A 3Q2BA 1TVJA 1T3XA 3EG9B 2NUTB 2NUPB 4PKIG 3CI5G 2HD7A 2MV2A 3EGDA 1CFYA 2LXXA 1C0FS 1SVRA 4S10C 5L6WC 1KCQA 1AHQA 1SVYA
chains in the Genus database with same CATH topology
3EG9A 2NUTA 2NUPA 1T3YA 1J72A 1CNUA 2FF6G 2VACA 3EFOB 2FH2A 2D8BA 1M2VB 3CJCG 1F7SA 3FG7A 1Q8XA 4KEDA 1M4JA 1WNJA 1YVNG 1AK7A 5KYWB 5KYXB 4LIZA 4CBWG 1COFA 2QTVA 1HQZ1 2FH4A 1UDMA 1AK6A 3EFOA 1M2VA 4PKHB 1VKKA 3DAWB 1PD1A 3FFKA 3FFNA 4CBUG 2I2QA 1RGIG 3A5MS 3CIPG 1P8ZG 1ESVS 2XF1A 4JD2H 2VILA 4KEFA 5HVKB 5KYWA 1WFSA 3DA7A 5KYXA 1X67A 1SVQA 1DEJS 3CJBG 3FG6A 5KYYB 1C0GS 3A5LS 1NLVG 4CBXG 1PD0A 2FF3A 2XFAA 3TU5B 1V6FA 5KYNA 1T44G 1Q8GA 1YAGG 5KYUB 1T2LA 1D4XG 5KYYA 2VIKA 3EH1A 5FAEA 5A1MA 3EGXB 1P8XA 1D0NA 3A5OS 2LLFA 1WM4A 1PCXA 1NM1G 2W0IA 1NPHA 5KYUA 2LJ8A 5IVUA 1MDUA 3L50A 5HVKD 4Z94G 5DD2A 1JHWA 4PKGG 3EGXA 1EQYS 1H1VG 1VFQA 2KVKA 3A5NS 1TMWA 2FH3A 4KEEA 1QPVA 5FAFA 3EH2A 1NMDG 3EGDB 2FGHA 2MOTA 2L72A 1M2OA 2FH1A 4BEX1 2MP4A 3Q2BA 1TVJA 1T3XA 3EG9B 2NUTB 2NUPB 4PKIG 3CI5G 2HD7A 2MV2A 3EGDA 1CFYA 2LXXA 1C0FS 1SVRA 4S10C 5L6WC 1KCQA 1AHQA 1SVYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3EG9 A;  2NUT A;  2NUP A;  1T3Y A;  1J72 A;  1CNU A;  2FF6 G;  2VAC A;  3EFO B;  2FH2 A;  2D8B A;  1M2V B;  3CJC G;  1F7S A;  3FG7 A;  1Q8X A;  4KED A;  1M4J A;  1WNJ A;  1YVN G;  1AK7 A;  5KYW B;  5KYX B;  4LIZ A;  4CBW G;  1COF A;  2QTV A;  1HQZ 1;  2FH4 A;  1UDM A;  1AK6 A;  3EFO A;  1M2V A;  4PKH B;  1VKK A;  3DAW B;  1PD1 A;  3FFK A;  3FFN A;  4CBU G;  2I2Q A;  1RGI G;  3A5M S;  3CIP G;  1P8Z G;  1ESV S;  2XF1 A;  4JD2 H;  2VIL A;  4KEF A;  5HVK B;  5KYW A;  1WFS A;  5KYX A;  1X67 A;  1SVQ A;  1DEJ S;  3CJB G;  3FG6 A;  5KYY B;  1C0G S;  3A5L S;  1NLV G;  4CBX G;  1PD0 A;  2FF3 A;  2XFA A;  3TU5 B;  1V6F A;  5KYN A;  1T44 G;  1Q8G A;  1YAG G;  5KYU B;  1T2L A;  1D4X G;  5KYY A;  2VIK A;  3EH1 A;  5FAE A;  5A1M A;  3EGX B;  1P8X A;  1D0N A;  3A5O S;  2LLF A;  1WM4 A;  1PCX A;  1NM1 G;  2W0I A;  1NPH A;  5KYU A;  2LJ8 A;  5IVU A;  1MDU A;  3L50 A;  5HVK D;  4Z94 G;  5DD2 A;  1JHW A;  4PKG G;  3EGX A;  1EQY S;  1H1V G;  1VFQ A;  2KVK A;  3A5N S;  1TMW A;  2FH3 A;  4KEE A;  1QPV A;  5FAF A;  3EH2 A;  1NMD G;  3EGD B;  2FGH A;  2MOT A;  2L72 A;  1M2O A;  2FH1 A;  4BEX 1;  2MP4 A;  3Q2B A;  1TVJ A;  1T3X A;  3EG9 B;  2NUT B;  2NUP B;  4PKI G;  3CI5 G;  2HD7 A;  2MV2 A;  3EGD A;  1CFY A;  2LXX A;  1C0F S;  1SVR A;  4S10 C;  5L6W C;  1KCQ A;  1AHQ A;  1SVY A; 
#chains in the Genus database with same CATH topology
 3EG9 A;  2NUT A;  2NUP A;  1T3Y A;  1J72 A;  1CNU A;  2FF6 G;  2VAC A;  3EFO B;  2FH2 A;  2D8B A;  1M2V B;  3CJC G;  1F7S A;  3FG7 A;  1Q8X A;  4KED A;  1M4J A;  1WNJ A;  1YVN G;  1AK7 A;  5KYW B;  5KYX B;  4LIZ A;  4CBW G;  1COF A;  2QTV A;  1HQZ 1;  2FH4 A;  1UDM A;  1AK6 A;  3EFO A;  1M2V A;  4PKH B;  1VKK A;  3DAW B;  1PD1 A;  3FFK A;  3FFN A;  4CBU G;  2I2Q A;  1RGI G;  3A5M S;  3CIP G;  1P8Z G;  1ESV S;  2XF1 A;  4JD2 H;  2VIL A;  4KEF A;  5HVK B;  5KYW A;  1WFS A;  3DA7 A;  5KYX A;  1X67 A;  1SVQ A;  1DEJ S;  3CJB G;  3FG6 A;  5KYY B;  1C0G S;  3A5L S;  1NLV G;  4CBX G;  1PD0 A;  2FF3 A;  2XFA A;  3TU5 B;  1V6F A;  5KYN A;  1T44 G;  1Q8G A;  1YAG G;  5KYU B;  1T2L A;  1D4X G;  5KYY A;  2VIK A;  3EH1 A;  5FAE A;  5A1M A;  3EGX B;  1P8X A;  1D0N A;  3A5O S;  2LLF A;  1WM4 A;  1PCX A;  1NM1 G;  2W0I A;  1NPH A;  5KYU A;  2LJ8 A;  5IVU A;  1MDU A;  3L50 A;  5HVK D;  4Z94 G;  5DD2 A;  1JHW A;  4PKG G;  3EGX A;  1EQY S;  1H1V G;  1VFQ A;  2KVK A;  3A5N S;  1TMW A;  2FH3 A;  4KEE A;  1QPV A;  5FAF A;  3EH2 A;  1NMD G;  3EGD B;  2FGH A;  2MOT A;  2L72 A;  1M2O A;  2FH1 A;  4BEX 1;  2MP4 A;  3Q2B A;  1TVJ A;  1T3X A;  3EG9 B;  2NUT B;  2NUP B;  4PKI G;  3CI5 G;  2HD7 A;  2MV2 A;  3EGD A;  1CFY A;  2LXX A;  1C0F S;  1SVR A;  4S10 C;  5L6W C;  1KCQ A;  1AHQ A;  1SVY A; 
#chains in the Genus database with same CATH homology
 3EG9 A;  2NUT A;  2NUP A;  1T3Y A;  1J72 A;  1CNU A;  2FF6 G;  2VAC A;  3EFO B;  2FH2 A;  2D8B A;  1M2V B;  3CJC G;  1F7S A;  3FG7 A;  1Q8X A;  4KED A;  1M4J A;  1WNJ A;  1YVN G;  1AK7 A;  5KYW B;  5KYX B;  4LIZ A;  4CBW G;  1COF A;  2QTV A;  1HQZ 1;  2FH4 A;  1UDM A;  1AK6 A;  3EFO A;  1M2V A;  4PKH B;  1VKK A;  3DAW B;  1PD1 A;  3FFK A;  3FFN A;  4CBU G;  2I2Q A;  1RGI G;  3A5M S;  3CIP G;  1P8Z G;  1ESV S;  2XF1 A;  4JD2 H;  2VIL A;  4KEF A;  5HVK B;  5KYW A;  1WFS A;  3DA7 A;  5KYX A;  1X67 A;  1SVQ A;  1DEJ S;  3CJB G;  3FG6 A;  5KYY B;  1C0G S;  3A5L S;  1NLV G;  4CBX G;  1PD0 A;  2FF3 A;  2XFA A;  3TU5 B;  1V6F A;  5KYN A;  1T44 G;  1Q8G A;  1YAG G;  5KYU B;  1T2L A;  1D4X G;  5KYY A;  2VIK A;  3EH1 A;  5FAE A;  5A1M A;  3EGX B;  1P8X A;  1D0N A;  3A5O S;  2LLF A;  1WM4 A;  1PCX A;  1NM1 G;  2W0I A;  1NPH A;  5KYU A;  2LJ8 A;  5IVU A;  1MDU A;  3L50 A;  5HVK D;  4Z94 G;  5DD2 A;  1JHW A;  4PKG G;  3EGX A;  1EQY S;  1H1V G;  1VFQ A;  2KVK A;  3A5N S;  1TMW A;  2FH3 A;  4KEE A;  1QPV A;  5FAF A;  3EH2 A;  1NMD G;  3EGD B;  2FGH A;  2MOT A;  2L72 A;  1M2O A;  2FH1 A;  4BEX 1;  2MP4 A;  3Q2B A;  1TVJ A;  1T3X A;  3EG9 B;  2NUT B;  2NUP B;  4PKI G;  3CI5 G;  2HD7 A;  2MV2 A;  3EGD A;  1CFY A;  2LXX A;  1C0F S;  1SVR A;  4S10 C;  5L6W C;  1KCQ A;  1AHQ A;  1SVY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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