1SVYA

Severin domain 2, 1.75 angstrom crystal structure
Total Genus 28
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
28
sequence length
102
structure length
101
Chain Sequence
EYKPRLLHISGDKNAKVAEVPLATSSLNSGDCFLLDAGLTIYQFNGSKSSPQEKNKAAEVARAIDAERKGLPKVEVFETDSDIPAEFWKLLGGKGAIAAKH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Mapping the functional surface of domain 2 in the gelsolin superfamily.
pubmed doi rcsb
molecule tags Actin-binding protein
source organism Dictyostelium discoideum
molecule keywords SEVERIN
total genus 28
structure length 101
sequence length 102
ec nomenclature
pdb deposition date 1998-08-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00626 Gelsolin Gelsolin repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 1svyA00
1T2LA 1VKKA 1Q8GA 3EFOB 3EH1A 3FG6A 2MOTA 1C0GS 1NMDG 1M2VB 1RGIG 1YAGG 3EGXA 5KYUA 5FAEA 3CI5G 3EGXB 3TU5B 1VFQA 3EH2A 1NM1G 2MV2A 2VIKA 1TMWA 2FH2A 5KYXA 3FFNA 1J72A 2VILA 3A5NS 1JHWA 1M2OA 1EQYS 5KYXB 2D8BA 1C0FS 3EFOA 1WNJA 5DD2A 1T44G 2MP4A 3A5MS 1X67A 1TVJA 1AK6A 2W0IA 1M2VA 4PKIG 1WM4A 2FH4A 2LJ8A 2KVKA 1AHQA 1T3XA 5KYNA 1F7SA 1PD0A 1T3YA 1P8XA 2NUTA 5KYYA 1COFA 2NUTB 2NUPA 5KYYB 1NLVG 3EG9B 1YVNG 2VACA 4LIZA 2XF1A 1PD1A 5A1MA 2NUPB 1SVQA 2I2QA 1SVRA 1CFYA 4PKGG 1AK7A 2FH3A 1MDUA 4KEDA 4S10C 2FGHA 3FG7A 2HD7A 2LXXA 4CBUG 5L6WC 4KEEA 1QPVA 2FF6G 1P8ZG 4JD2H 4CBWG 2QTVA 3DAWB 1WFSA 3EG9A 4KEFA 5KYWB 2FH1A 1Q8XA 1D4XG 3CJBG 1V6FA 5HVKD 1NPHA 4BEX1 1ESVS 4Z94G 3A5OS 1DEJS 1M4JA 2L72A 3CIPG 5HVKB 5FAFA 3CJCG 1PCXA 3FFKA 2FF3A 1UDMA 3EGDA 5KYUB 1CNUA 1D0NA 4PKHB 1HQZ1 3L50A 5KYWA 3Q2BA 2LLFA 3EGDB 3A5LS 1KCQA 5IVUA 4CBXG 2XFAA 1H1VG 1SVYA
chains in the Genus database with same CATH superfamily
1T2LA 1VKKA 1Q8GA 3EFOB 3EH1A 3FG6A 2MOTA 1C0GS 1NMDG 1M2VB 1RGIG 1YAGG 3EGXA 5KYUA 5FAEA 3CI5G 3EGXB 3TU5B 1VFQA 3EH2A 1NM1G 2MV2A 2VIKA 1TMWA 2FH2A 5KYXA 3FFNA 1J72A 2VILA 3A5NS 1JHWA 1M2OA 1EQYS 5KYXB 2D8BA 1C0FS 3EFOA 1WNJA 5DD2A 1T44G 2MP4A 3A5MS 1X67A 1TVJA 1AK6A 2W0IA 1M2VA 4PKIG 1WM4A 2FH4A 2LJ8A 2KVKA 1AHQA 1T3XA 5KYNA 1F7SA 1PD0A 1T3YA 1P8XA 2NUTA 5KYYA 1COFA 2NUTB 3DA7A 2NUPA 5KYYB 1NLVG 3EG9B 1YVNG 2VACA 4LIZA 2XF1A 1PD1A 5A1MA 2NUPB 1SVQA 2I2QA 1SVRA 1CFYA 4PKGG 1AK7A 2FH3A 1MDUA 4KEDA 4S10C 2FGHA 3FG7A 2HD7A 2LXXA 4CBUG 5L6WC 4KEEA 1QPVA 2FF6G 1P8ZG 4JD2H 4CBWG 2QTVA 3DAWB 1WFSA 3EG9A 4KEFA 5KYWB 2FH1A 1Q8XA 1D4XG 3CJBG 1V6FA 5HVKD 1NPHA 4BEX1 1ESVS 4Z94G 3A5OS 1DEJS 1M4JA 2L72A 3CIPG 5HVKB 5FAFA 3CJCG 1PCXA 3FFKA 2FF3A 1UDMA 3EGDA 5KYUB 1CNUA 1D0NA 4PKHB 1HQZ1 3L50A 5KYWA 3Q2BA 2LLFA 3EGDB 3A5LS 1KCQA 5IVUA 4CBXG 2XFAA 1H1VG 1SVYA
chains in the Genus database with same CATH topology
1T2LA 1VKKA 1Q8GA 3EFOB 3EH1A 3FG6A 2MOTA 1C0GS 1NMDG 1M2VB 1RGIG 1YAGG 3EGXA 5KYUA 5FAEA 3CI5G 3EGXB 3TU5B 1VFQA 3EH2A 1NM1G 2MV2A 2VIKA 1TMWA 2FH2A 5KYXA 3FFNA 1J72A 2VILA 3A5NS 1JHWA 1M2OA 1EQYS 5KYXB 2D8BA 1C0FS 3EFOA 1WNJA 5DD2A 1T44G 2MP4A 3A5MS 1X67A 1TVJA 1AK6A 2W0IA 1M2VA 4PKIG 1WM4A 2FH4A 2LJ8A 2KVKA 1AHQA 1T3XA 5KYNA 1F7SA 1PD0A 1T3YA 1P8XA 2NUTA 5KYYA 1COFA 2NUTB 3DA7A 2NUPA 5KYYB 1NLVG 3EG9B 1YVNG 2VACA 4LIZA 2XF1A 1PD1A 5A1MA 2NUPB 1SVQA 2I2QA 1SVRA 1CFYA 4PKGG 1AK7A 2FH3A 1MDUA 4KEDA 4S10C 2FGHA 3FG7A 2HD7A 2LXXA 4CBUG 5L6WC 4KEEA 1QPVA 2FF6G 1P8ZG 4JD2H 4CBWG 2QTVA 3DAWB 1WFSA 3EG9A 4KEFA 5KYWB 2FH1A 1Q8XA 1D4XG 3CJBG 1V6FA 5HVKD 1NPHA 4BEX1 1ESVS 4Z94G 3A5OS 1DEJS 1M4JA 2L72A 3CIPG 5HVKB 5FAFA 3CJCG 1PCXA 3FFKA 2FF3A 1UDMA 3EGDA 5KYUB 1CNUA 1D0NA 4PKHB 1HQZ1 3L50A 5KYWA 3Q2BA 2LLFA 3EGDB 3A5LS 1KCQA 5IVUA 4CBXG 2XFAA 1H1VG 1SVYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1T2L A;  1VKK A;  1Q8G A;  3EFO B;  3EH1 A;  3FG6 A;  2MOT A;  1C0G S;  1NMD G;  1M2V B;  1RGI G;  1YAG G;  3EGX A;  5KYU A;  5FAE A;  3CI5 G;  3EGX B;  3TU5 B;  1VFQ A;  3EH2 A;  1NM1 G;  2MV2 A;  2VIK A;  1TMW A;  2FH2 A;  5KYX A;  3FFN A;  1J72 A;  2VIL A;  3A5N S;  1JHW A;  1M2O A;  1EQY S;  5KYX B;  2D8B A;  1C0F S;  3EFO A;  1WNJ A;  5DD2 A;  1T44 G;  2MP4 A;  3A5M S;  1X67 A;  1TVJ A;  1AK6 A;  2W0I A;  1M2V A;  4PKI G;  1WM4 A;  2FH4 A;  2LJ8 A;  2KVK A;  1AHQ A;  1T3X A;  5KYN A;  1F7S A;  1PD0 A;  1T3Y A;  1P8X A;  2NUT A;  5KYY A;  1COF A;  2NUT B;  2NUP A;  5KYY B;  1NLV G;  3EG9 B;  1YVN G;  2VAC A;  4LIZ A;  2XF1 A;  1PD1 A;  5A1M A;  2NUP B;  1SVQ A;  2I2Q A;  1SVR A;  1CFY A;  4PKG G;  1AK7 A;  2FH3 A;  1MDU A;  4KED A;  4S10 C;  2FGH A;  3FG7 A;  2HD7 A;  2LXX A;  4CBU G;  5L6W C;  4KEE A;  1QPV A;  2FF6 G;  1P8Z G;  4JD2 H;  4CBW G;  2QTV A;  3DAW B;  1WFS A;  3EG9 A;  4KEF A;  5KYW B;  2FH1 A;  1Q8X A;  1D4X G;  3CJB G;  1V6F A;  5HVK D;  1NPH A;  4BEX 1;  1ESV S;  4Z94 G;  3A5O S;  1DEJ S;  1M4J A;  2L72 A;  3CIP G;  5HVK B;  5FAF A;  3CJC G;  1PCX A;  3FFK A;  2FF3 A;  1UDM A;  3EGD A;  5KYU B;  1CNU A;  1D0N A;  4PKH B;  1HQZ 1;  3L50 A;  5KYW A;  3Q2B A;  2LLF A;  3EGD B;  3A5L S;  1KCQ A;  5IVU A;  4CBX G;  2XFA A;  1H1V G;  1SVY A; 
#chains in the Genus database with same CATH topology
 1T2L A;  1VKK A;  1Q8G A;  3EFO B;  3EH1 A;  3FG6 A;  2MOT A;  1C0G S;  1NMD G;  1M2V B;  1RGI G;  1YAG G;  3EGX A;  5KYU A;  5FAE A;  3CI5 G;  3EGX B;  3TU5 B;  1VFQ A;  3EH2 A;  1NM1 G;  2MV2 A;  2VIK A;  1TMW A;  2FH2 A;  5KYX A;  3FFN A;  1J72 A;  2VIL A;  3A5N S;  1JHW A;  1M2O A;  1EQY S;  5KYX B;  2D8B A;  1C0F S;  3EFO A;  1WNJ A;  5DD2 A;  1T44 G;  2MP4 A;  3A5M S;  1X67 A;  1TVJ A;  1AK6 A;  2W0I A;  1M2V A;  4PKI G;  1WM4 A;  2FH4 A;  2LJ8 A;  2KVK A;  1AHQ A;  1T3X A;  5KYN A;  1F7S A;  1PD0 A;  1T3Y A;  1P8X A;  2NUT A;  5KYY A;  1COF A;  2NUT B;  3DA7 A;  2NUP A;  5KYY B;  1NLV G;  3EG9 B;  1YVN G;  2VAC A;  4LIZ A;  2XF1 A;  1PD1 A;  5A1M A;  2NUP B;  1SVQ A;  2I2Q A;  1SVR A;  1CFY A;  4PKG G;  1AK7 A;  2FH3 A;  1MDU A;  4KED A;  4S10 C;  2FGH A;  3FG7 A;  2HD7 A;  2LXX A;  4CBU G;  5L6W C;  4KEE A;  1QPV A;  2FF6 G;  1P8Z G;  4JD2 H;  4CBW G;  2QTV A;  3DAW B;  1WFS A;  3EG9 A;  4KEF A;  5KYW B;  2FH1 A;  1Q8X A;  1D4X G;  3CJB G;  1V6F A;  5HVK D;  1NPH A;  4BEX 1;  1ESV S;  4Z94 G;  3A5O S;  1DEJ S;  1M4J A;  2L72 A;  3CIP G;  5HVK B;  5FAF A;  3CJC G;  1PCX A;  3FFK A;  2FF3 A;  1UDM A;  3EGD A;  5KYU B;  1CNU A;  1D0N A;  4PKH B;  1HQZ 1;  3L50 A;  5KYW A;  3Q2B A;  2LLF A;  3EGD B;  3A5L S;  1KCQ A;  5IVU A;  4CBX G;  2XFA A;  1H1V G;  1SVY A; 
#chains in the Genus database with same CATH homology
 1T2L A;  1VKK A;  1Q8G A;  3EFO B;  3EH1 A;  3FG6 A;  2MOT A;  1C0G S;  1NMD G;  1M2V B;  1RGI G;  1YAG G;  3EGX A;  5KYU A;  5FAE A;  3CI5 G;  3EGX B;  3TU5 B;  1VFQ A;  3EH2 A;  1NM1 G;  2MV2 A;  2VIK A;  1TMW A;  2FH2 A;  5KYX A;  3FFN A;  1J72 A;  2VIL A;  3A5N S;  1JHW A;  1M2O A;  1EQY S;  5KYX B;  2D8B A;  1C0F S;  3EFO A;  1WNJ A;  5DD2 A;  1T44 G;  2MP4 A;  3A5M S;  1X67 A;  1TVJ A;  1AK6 A;  2W0I A;  1M2V A;  4PKI G;  1WM4 A;  2FH4 A;  2LJ8 A;  2KVK A;  1AHQ A;  1T3X A;  5KYN A;  1F7S A;  1PD0 A;  1T3Y A;  1P8X A;  2NUT A;  5KYY A;  1COF A;  2NUT B;  3DA7 A;  2NUP A;  5KYY B;  1NLV G;  3EG9 B;  1YVN G;  2VAC A;  4LIZ A;  2XF1 A;  1PD1 A;  5A1M A;  2NUP B;  1SVQ A;  2I2Q A;  1SVR A;  1CFY A;  4PKG G;  1AK7 A;  2FH3 A;  1MDU A;  4KED A;  4S10 C;  2FGH A;  3FG7 A;  2HD7 A;  2LXX A;  4CBU G;  5L6W C;  4KEE A;  1QPV A;  2FF6 G;  1P8Z G;  4JD2 H;  4CBW G;  2QTV A;  3DAW B;  1WFS A;  3EG9 A;  4KEF A;  5KYW B;  2FH1 A;  1Q8X A;  1D4X G;  3CJB G;  1V6F A;  5HVK D;  1NPH A;  4BEX 1;  1ESV S;  4Z94 G;  3A5O S;  1DEJ S;  1M4J A;  2L72 A;  3CIP G;  5HVK B;  5FAF A;  3CJC G;  1PCX A;  3FFK A;  2FF3 A;  1UDM A;  3EGD A;  5KYU B;  1CNU A;  1D0N A;  4PKH B;  1HQZ 1;  3L50 A;  5KYW A;  3Q2B A;  2LLF A;  3EGD B;  3A5L S;  1KCQ A;  5IVU A;  4CBX G;  2XFA A;  1H1V G;  1SVY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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