1TVJA

Solution structure of chick cofilin
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
166
structure length
166
Chain Sequence
MASGVTVNDEVIKVFNDMKVRKSSTPEEIKKRKKAVLFCLSDDKKQIIVEEAKQILVGDIGDTVEDPYTAFVKLLPLNDCRYALYDATYETKESKKEDLVFIFWAPESAPLKSKMIYASSKDAIKKKFTGIKHEWQVNGLDDIKDRSTLGEKLGGNVVVSLEGKPL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title NMR Study of the Molecular Basis for Phosphoinositide Regulation of the Cofilin-Actin Interactions.
rcsb
molecule tags Actin-binding protein
source organism Gallus gallus
molecule keywords Cofilin
total genus 35
structure length 166
sequence length 166
ec nomenclature
pdb deposition date 2004-06-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00241 Cofilin_ADF Cofilin/tropomyosin-type actin-binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 1tvjA00
2W0IA 1AHQA 1NLVG 1C0GS 3A5OS 1NM1G 4KEEA 5KYWA 3EGDB 2MV2A 1WNJA 3FG6A 3EH1A 1NMDG 1F7SA 4S10C 1CFYA 2LXXA 5KYYA 1VFQA 4Z94G 1TMWA 5KYNA 1C0FS 1P8XA 2FH1A 1UDMA 5HVKB 2XFAA 3FFKA 1TVJA 2D8BA 1NPHA 1M2VB 4CBXG 1KCQA 2NUPB 2VIKA 1D0NA 3L50A 1PCXA 1YAGG 3CI5G 2MOTA 1M4JA 2XF1A 1J72A 3TU5B 1T44G 1COFA 3EGDA 1AK7A 2NUTB 1EQYS 2KVKA 3EH2A 1WM4A 1QPVA 1RGIG 5DD2A 1SVRA 2QTVA 2LJ8A 2MP4A 3FG7A 2I2QA 3EG9B 1ESVS 1H1VG 2HD7A 4PKGG 2FF3A 2FGHA 3A5NS 2FF6G 1M2VA 4CBUG 5KYXB 2NUPA 1PD0A 5HVKD 4PKIG 5FAFA 1Q8XA 1V6FA 1M2OA 1CNUA 5KYUB 3EFOB 2NUTA 5IVUA 1T3YA 3Q2BA 1SVYA 1JHWA 2FH4A 4CBWG 4LIZA 3EGXB 1MDUA 1D4XG 1Q8GA 1T2LA 3CJBG 3EG9A 4PKHB 2VILA 1P8ZG 2VACA 5KYWB 1WFSA 1AK6A 3A5LS 4JD2H 5KYXA 1SVQA 2FH3A 2FH2A 1T3XA 3CJCG 5KYYB 1YVNG 1X67A 4KEDA 1HQZ1 5A1MA 3FFNA 1DEJS 5KYUA 3EFOA 3A5MS 2L72A 3DAWB 5L6WC 1PD1A 1VKKA 3CIPG 2LLFA 4BEX1 5FAEA 3EGXA 4KEFA
chains in the Genus database with same CATH superfamily
2W0IA 1AHQA 1NLVG 1C0GS 3A5OS 1NM1G 4KEEA 5KYWA 3EGDB 2MV2A 1WNJA 3FG6A 3EH1A 1NMDG 1F7SA 4S10C 1CFYA 2LXXA 5KYYA 1VFQA 4Z94G 1TMWA 5KYNA 1C0FS 1P8XA 2FH1A 1UDMA 5HVKB 2XFAA 3FFKA 1TVJA 2D8BA 1NPHA 1M2VB 4CBXG 1KCQA 2NUPB 2VIKA 1D0NA 3L50A 1PCXA 1YAGG 3CI5G 2MOTA 1M4JA 2XF1A 1J72A 3TU5B 1T44G 1COFA 3EGDA 1AK7A 2NUTB 1EQYS 2KVKA 3EH2A 1WM4A 1QPVA 1RGIG 5DD2A 1SVRA 2QTVA 2LJ8A 2MP4A 3FG7A 2I2QA 3EG9B 1ESVS 1H1VG 2HD7A 4PKGG 2FF3A 2FGHA 3A5NS 2FF6G 1M2VA 4CBUG 5KYXB 2NUPA 1PD0A 3DA7A 5HVKD 4PKIG 5FAFA 1Q8XA 1V6FA 1M2OA 1CNUA 5KYUB 3EFOB 2NUTA 5IVUA 1T3YA 3Q2BA 1SVYA 1JHWA 2FH4A 4CBWG 4LIZA 3EGXB 1MDUA 1D4XG 1Q8GA 1T2LA 3CJBG 3EG9A 4PKHB 2VILA 1P8ZG 2VACA 5KYWB 1WFSA 1AK6A 3A5LS 4JD2H 5KYXA 1SVQA 2FH3A 2FH2A 1T3XA 3CJCG 5KYYB 1YVNG 1X67A 4KEDA 1HQZ1 5A1MA 3FFNA 1DEJS 5KYUA 3EFOA 3A5MS 2L72A 3DAWB 5L6WC 1PD1A 1VKKA 3CIPG 2LLFA 4BEX1 5FAEA 3EGXA 4KEFA
chains in the Genus database with same CATH topology
2W0IA 1AHQA 1NLVG 1C0GS 3A5OS 1NM1G 4KEEA 5KYWA 3EGDB 2MV2A 1WNJA 3FG6A 3EH1A 1NMDG 1F7SA 4S10C 1CFYA 2LXXA 5KYYA 1VFQA 4Z94G 1TMWA 5KYNA 1C0FS 1P8XA 2FH1A 1UDMA 5HVKB 2XFAA 3FFKA 1TVJA 2D8BA 1NPHA 1M2VB 4CBXG 1KCQA 2NUPB 2VIKA 1D0NA 3L50A 1PCXA 1YAGG 3CI5G 2MOTA 1M4JA 2XF1A 1J72A 3TU5B 1T44G 1COFA 3EGDA 1AK7A 2NUTB 1EQYS 2KVKA 3EH2A 1WM4A 1QPVA 1RGIG 5DD2A 1SVRA 2QTVA 2LJ8A 2MP4A 3FG7A 2I2QA 3EG9B 1ESVS 1H1VG 2HD7A 4PKGG 2FF3A 2FGHA 3A5NS 2FF6G 1M2VA 4CBUG 5KYXB 2NUPA 1PD0A 3DA7A 5HVKD 4PKIG 5FAFA 1Q8XA 1V6FA 1M2OA 1CNUA 5KYUB 3EFOB 2NUTA 5IVUA 1T3YA 3Q2BA 1SVYA 1JHWA 2FH4A 4CBWG 4LIZA 3EGXB 1MDUA 1D4XG 1Q8GA 1T2LA 3CJBG 3EG9A 4PKHB 2VILA 1P8ZG 2VACA 5KYWB 1WFSA 1AK6A 3A5LS 4JD2H 5KYXA 1SVQA 2FH3A 2FH2A 1T3XA 3CJCG 5KYYB 1YVNG 1X67A 4KEDA 1HQZ1 5A1MA 3FFNA 1DEJS 5KYUA 3EFOA 3A5MS 2L72A 3DAWB 5L6WC 1PD1A 1VKKA 3CIPG 2LLFA 4BEX1 5FAEA 3EGXA 4KEFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2W0I A;  1AHQ A;  1NLV G;  1C0G S;  3A5O S;  1NM1 G;  4KEE A;  5KYW A;  3EGD B;  2MV2 A;  1WNJ A;  3FG6 A;  3EH1 A;  1NMD G;  1F7S A;  4S10 C;  1CFY A;  2LXX A;  5KYY A;  1VFQ A;  4Z94 G;  1TMW A;  5KYN A;  1C0F S;  1P8X A;  2FH1 A;  1UDM A;  5HVK B;  2XFA A;  3FFK A;  1TVJ A;  2D8B A;  1NPH A;  1M2V B;  4CBX G;  1KCQ A;  2NUP B;  2VIK A;  1D0N A;  3L50 A;  1PCX A;  1YAG G;  3CI5 G;  2MOT A;  1M4J A;  2XF1 A;  1J72 A;  3TU5 B;  1T44 G;  1COF A;  3EGD A;  1AK7 A;  2NUT B;  1EQY S;  2KVK A;  3EH2 A;  1WM4 A;  1QPV A;  1RGI G;  5DD2 A;  1SVR A;  2QTV A;  2LJ8 A;  2MP4 A;  3FG7 A;  2I2Q A;  3EG9 B;  1ESV S;  1H1V G;  2HD7 A;  4PKG G;  2FF3 A;  2FGH A;  3A5N S;  2FF6 G;  1M2V A;  4CBU G;  5KYX B;  2NUP A;  1PD0 A;  5HVK D;  4PKI G;  5FAF A;  1Q8X A;  1V6F A;  1M2O A;  1CNU A;  5KYU B;  3EFO B;  2NUT A;  5IVU A;  1T3Y A;  3Q2B A;  1SVY A;  1JHW A;  2FH4 A;  4CBW G;  4LIZ A;  3EGX B;  1MDU A;  1D4X G;  1Q8G A;  1T2L A;  3CJB G;  3EG9 A;  4PKH B;  2VIL A;  1P8Z G;  2VAC A;  5KYW B;  1WFS A;  1AK6 A;  3A5L S;  4JD2 H;  5KYX A;  1SVQ A;  2FH3 A;  2FH2 A;  1T3X A;  3CJC G;  5KYY B;  1YVN G;  1X67 A;  4KED A;  1HQZ 1;  5A1M A;  3FFN A;  1DEJ S;  5KYU A;  3EFO A;  3A5M S;  2L72 A;  3DAW B;  5L6W C;  1PD1 A;  1VKK A;  3CIP G;  2LLF A;  4BEX 1;  5FAE A;  3EGX A;  4KEF A; 
#chains in the Genus database with same CATH topology
 2W0I A;  1AHQ A;  1NLV G;  1C0G S;  3A5O S;  1NM1 G;  4KEE A;  5KYW A;  3EGD B;  2MV2 A;  1WNJ A;  3FG6 A;  3EH1 A;  1NMD G;  1F7S A;  4S10 C;  1CFY A;  2LXX A;  5KYY A;  1VFQ A;  4Z94 G;  1TMW A;  5KYN A;  1C0F S;  1P8X A;  2FH1 A;  1UDM A;  5HVK B;  2XFA A;  3FFK A;  1TVJ A;  2D8B A;  1NPH A;  1M2V B;  4CBX G;  1KCQ A;  2NUP B;  2VIK A;  1D0N A;  3L50 A;  1PCX A;  1YAG G;  3CI5 G;  2MOT A;  1M4J A;  2XF1 A;  1J72 A;  3TU5 B;  1T44 G;  1COF A;  3EGD A;  1AK7 A;  2NUT B;  1EQY S;  2KVK A;  3EH2 A;  1WM4 A;  1QPV A;  1RGI G;  5DD2 A;  1SVR A;  2QTV A;  2LJ8 A;  2MP4 A;  3FG7 A;  2I2Q A;  3EG9 B;  1ESV S;  1H1V G;  2HD7 A;  4PKG G;  2FF3 A;  2FGH A;  3A5N S;  2FF6 G;  1M2V A;  4CBU G;  5KYX B;  2NUP A;  1PD0 A;  3DA7 A;  5HVK D;  4PKI G;  5FAF A;  1Q8X A;  1V6F A;  1M2O A;  1CNU A;  5KYU B;  3EFO B;  2NUT A;  5IVU A;  1T3Y A;  3Q2B A;  1SVY A;  1JHW A;  2FH4 A;  4CBW G;  4LIZ A;  3EGX B;  1MDU A;  1D4X G;  1Q8G A;  1T2L A;  3CJB G;  3EG9 A;  4PKH B;  2VIL A;  1P8Z G;  2VAC A;  5KYW B;  1WFS A;  1AK6 A;  3A5L S;  4JD2 H;  5KYX A;  1SVQ A;  2FH3 A;  2FH2 A;  1T3X A;  3CJC G;  5KYY B;  1YVN G;  1X67 A;  4KED A;  1HQZ 1;  5A1M A;  3FFN A;  1DEJ S;  5KYU A;  3EFO A;  3A5M S;  2L72 A;  3DAW B;  5L6W C;  1PD1 A;  1VKK A;  3CIP G;  2LLF A;  4BEX 1;  5FAE A;  3EGX A;  4KEF A; 
#chains in the Genus database with same CATH homology
 2W0I A;  1AHQ A;  1NLV G;  1C0G S;  3A5O S;  1NM1 G;  4KEE A;  5KYW A;  3EGD B;  2MV2 A;  1WNJ A;  3FG6 A;  3EH1 A;  1NMD G;  1F7S A;  4S10 C;  1CFY A;  2LXX A;  5KYY A;  1VFQ A;  4Z94 G;  1TMW A;  5KYN A;  1C0F S;  1P8X A;  2FH1 A;  1UDM A;  5HVK B;  2XFA A;  3FFK A;  1TVJ A;  2D8B A;  1NPH A;  1M2V B;  4CBX G;  1KCQ A;  2NUP B;  2VIK A;  1D0N A;  3L50 A;  1PCX A;  1YAG G;  3CI5 G;  2MOT A;  1M4J A;  2XF1 A;  1J72 A;  3TU5 B;  1T44 G;  1COF A;  3EGD A;  1AK7 A;  2NUT B;  1EQY S;  2KVK A;  3EH2 A;  1WM4 A;  1QPV A;  1RGI G;  5DD2 A;  1SVR A;  2QTV A;  2LJ8 A;  2MP4 A;  3FG7 A;  2I2Q A;  3EG9 B;  1ESV S;  1H1V G;  2HD7 A;  4PKG G;  2FF3 A;  2FGH A;  3A5N S;  2FF6 G;  1M2V A;  4CBU G;  5KYX B;  2NUP A;  1PD0 A;  3DA7 A;  5HVK D;  4PKI G;  5FAF A;  1Q8X A;  1V6F A;  1M2O A;  1CNU A;  5KYU B;  3EFO B;  2NUT A;  5IVU A;  1T3Y A;  3Q2B A;  1SVY A;  1JHW A;  2FH4 A;  4CBW G;  4LIZ A;  3EGX B;  1MDU A;  1D4X G;  1Q8G A;  1T2L A;  3CJB G;  3EG9 A;  4PKH B;  2VIL A;  1P8Z G;  2VAC A;  5KYW B;  1WFS A;  1AK6 A;  3A5L S;  4JD2 H;  5KYX A;  1SVQ A;  2FH3 A;  2FH2 A;  1T3X A;  3CJC G;  5KYY B;  1YVN G;  1X67 A;  4KED A;  1HQZ 1;  5A1M A;  3FFN A;  1DEJ S;  5KYU A;  3EFO A;  3A5M S;  2L72 A;  3DAW B;  5L6W C;  1PD1 A;  1VKK A;  3CIP G;  2LLF A;  4BEX 1;  5FAE A;  3EGX A;  4KEF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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