1WM4A

Solution structure of mouse coactosin, an actin filament binding protein
Total Genus 26
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
142
structure length
142
Chain Sequence
MATKIDKEACRAAYNLVRDDGSAVIWVTFRYDGATIVPGDQGADYQHFIQQCTDDVRLFAFVRFTTGDAMSKRSKFALITWIGEDVSGLQRAKTGTDKTLVKEVVQNFAKEFVISDRKELEEDFIRSELKKAGGANYDAQSE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Solution structure of coactosin reveals structural homology to ADF/cofilin family proteins
pubmed doi rcsb
molecule tags Protein binding
source organism Mus musculus
molecule keywords Coactosin-like protein
total genus 26
structure length 142
sequence length 142
ec nomenclature
pdb deposition date 2004-07-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00241 Cofilin_ADF Cofilin/tropomyosin-type actin-binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 1wm4A00
3FFNA 4CBWG 1NM1G 1MDUA 1TVJA 2VIKA 1PD0A 1YAGG 1SVYA 1F7SA 2FH2A 3CIPG 3A5MS 5HVKB 4KEEA 4PKHB 5KYXA 5FAEA 1M2OA 2LJ8A 2FGHA 3EGXA 1YVNG 2KVKA 4LIZA 2NUTA 5KYXB 1J72A 2HD7A 3EH1A 1WNJA 3A5NS 3CI5G 3EGXB 1SVRA 1C0FS 1COFA 2L72A 4S10C 1D4XG 2I2QA 1M2VA 1QPVA 2NUTB 1M4JA 4PKIG 4CBUG 3A5OS 1PCXA 1ESVS 1EQYS 1NPHA 5KYWA 3EFOA 5DD2A 2D8BA 4JD2H 1T3XA 1D0NA 1M2VB 1VKKA 1CFYA 4CBXG 5KYWB 3EFOB 2XF1A 5L6WC 3Q2BA 1UDMA 1WM4A 3CJBG 4PKGG 4KEFA 3EH2A 1T3YA 2MOTA 1PD1A 4Z94G 2LLFA 5KYUA 1Q8GA 3FG6A 2MV2A 2FH1A 4KEDA 3FG7A 3TU5B 3CJCG 3EGDA 1RGIG 5KYNA 2FH4A 1P8XA 2QTVA 2MP4A 1WFSA 5KYUB 1AK6A 2W0IA 2VACA 3EGDB 2FF3A 1H1VG 5FAFA 3EG9A 1JHWA 1T2LA 3DAWB 1C0GS 2NUPA 1NMDG 2VILA 1HQZ1 1CNUA 2FF6G 3EG9B 3L50A 4BEX1 1AHQA 2NUPB 1TMWA 2LXXA 1Q8XA 5KYYA 3A5LS 1SVQA 1T44G 5IVUA 2FH3A 1P8ZG 1DEJS 5A1MA 2XFAA 1NLVG 5HVKD 1VFQA 5KYYB 1V6FA 1X67A 1KCQA 3FFKA 1AK7A
chains in the Genus database with same CATH superfamily
3FFNA 4CBWG 1NM1G 1MDUA 1TVJA 2VIKA 1PD0A 1YAGG 1SVYA 1F7SA 2FH2A 3CIPG 3A5MS 5HVKB 4KEEA 4PKHB 5KYXA 5FAEA 1M2OA 2LJ8A 2FGHA 3EGXA 1YVNG 2KVKA 4LIZA 2NUTA 5KYXB 1J72A 2HD7A 3EH1A 1WNJA 3A5NS 3CI5G 3EGXB 1SVRA 1C0FS 1COFA 2L72A 4S10C 1D4XG 2I2QA 1M2VA 1QPVA 2NUTB 1M4JA 4PKIG 4CBUG 3A5OS 1PCXA 1ESVS 1EQYS 1NPHA 5KYWA 3EFOA 5DD2A 2D8BA 4JD2H 1T3XA 1D0NA 1M2VB 1VKKA 1CFYA 4CBXG 5KYWB 3EFOB 2XF1A 5L6WC 3Q2BA 1UDMA 1WM4A 3CJBG 4PKGG 4KEFA 3EH2A 1T3YA 2MOTA 1PD1A 4Z94G 2LLFA 5KYUA 1Q8GA 3FG6A 2MV2A 2FH1A 4KEDA 3FG7A 3TU5B 3CJCG 3EGDA 1RGIG 5KYNA 2FH4A 1P8XA 2QTVA 2MP4A 1WFSA 5KYUB 1AK6A 2W0IA 2VACA 3EGDB 3DA7A 2FF3A 1H1VG 5FAFA 3EG9A 1JHWA 1T2LA 3DAWB 1C0GS 2NUPA 1NMDG 2VILA 1HQZ1 1CNUA 2FF6G 3EG9B 3L50A 4BEX1 1AHQA 2NUPB 1TMWA 2LXXA 1Q8XA 5KYYA 3A5LS 1SVQA 1T44G 5IVUA 2FH3A 1P8ZG 1DEJS 5A1MA 2XFAA 1NLVG 5HVKD 1VFQA 5KYYB 1V6FA 1X67A 1KCQA 3FFKA 1AK7A
chains in the Genus database with same CATH topology
3FFNA 4CBWG 1NM1G 1MDUA 1TVJA 2VIKA 1PD0A 1YAGG 1SVYA 1F7SA 2FH2A 3CIPG 3A5MS 5HVKB 4KEEA 4PKHB 5KYXA 5FAEA 1M2OA 2LJ8A 2FGHA 3EGXA 1YVNG 2KVKA 4LIZA 2NUTA 5KYXB 1J72A 2HD7A 3EH1A 1WNJA 3A5NS 3CI5G 3EGXB 1SVRA 1C0FS 1COFA 2L72A 4S10C 1D4XG 2I2QA 1M2VA 1QPVA 2NUTB 1M4JA 4PKIG 4CBUG 3A5OS 1PCXA 1ESVS 1EQYS 1NPHA 5KYWA 3EFOA 5DD2A 2D8BA 4JD2H 1T3XA 1D0NA 1M2VB 1VKKA 1CFYA 4CBXG 5KYWB 3EFOB 2XF1A 5L6WC 3Q2BA 1UDMA 1WM4A 3CJBG 4PKGG 4KEFA 3EH2A 1T3YA 2MOTA 1PD1A 4Z94G 2LLFA 5KYUA 1Q8GA 3FG6A 2MV2A 2FH1A 4KEDA 3FG7A 3TU5B 3CJCG 3EGDA 1RGIG 5KYNA 2FH4A 1P8XA 2QTVA 2MP4A 1WFSA 5KYUB 1AK6A 2W0IA 2VACA 3EGDB 3DA7A 2FF3A 1H1VG 5FAFA 3EG9A 1JHWA 1T2LA 3DAWB 1C0GS 2NUPA 1NMDG 2VILA 1HQZ1 1CNUA 2FF6G 3EG9B 3L50A 4BEX1 1AHQA 2NUPB 1TMWA 2LXXA 1Q8XA 5KYYA 3A5LS 1SVQA 1T44G 5IVUA 2FH3A 1P8ZG 1DEJS 5A1MA 2XFAA 1NLVG 5HVKD 1VFQA 5KYYB 1V6FA 1X67A 1KCQA 3FFKA 1AK7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3FFN A;  4CBW G;  1NM1 G;  1MDU A;  1TVJ A;  2VIK A;  1PD0 A;  1YAG G;  1SVY A;  1F7S A;  2FH2 A;  3CIP G;  3A5M S;  5HVK B;  4KEE A;  4PKH B;  5KYX A;  5FAE A;  1M2O A;  2LJ8 A;  2FGH A;  3EGX A;  1YVN G;  2KVK A;  4LIZ A;  2NUT A;  5KYX B;  1J72 A;  2HD7 A;  3EH1 A;  1WNJ A;  3A5N S;  3CI5 G;  3EGX B;  1SVR A;  1C0F S;  1COF A;  2L72 A;  4S10 C;  1D4X G;  2I2Q A;  1M2V A;  1QPV A;  2NUT B;  1M4J A;  4PKI G;  4CBU G;  3A5O S;  1PCX A;  1ESV S;  1EQY S;  1NPH A;  5KYW A;  3EFO A;  5DD2 A;  2D8B A;  4JD2 H;  1T3X A;  1D0N A;  1M2V B;  1VKK A;  1CFY A;  4CBX G;  5KYW B;  3EFO B;  2XF1 A;  5L6W C;  3Q2B A;  1UDM A;  1WM4 A;  3CJB G;  4PKG G;  4KEF A;  3EH2 A;  1T3Y A;  2MOT A;  1PD1 A;  4Z94 G;  2LLF A;  5KYU A;  1Q8G A;  3FG6 A;  2MV2 A;  2FH1 A;  4KED A;  3FG7 A;  3TU5 B;  3CJC G;  3EGD A;  1RGI G;  5KYN A;  2FH4 A;  1P8X A;  2QTV A;  2MP4 A;  1WFS A;  5KYU B;  1AK6 A;  2W0I A;  2VAC A;  3EGD B;  2FF3 A;  1H1V G;  5FAF A;  3EG9 A;  1JHW A;  1T2L A;  3DAW B;  1C0G S;  2NUP A;  1NMD G;  2VIL A;  1HQZ 1;  1CNU A;  2FF6 G;  3EG9 B;  3L50 A;  4BEX 1;  1AHQ A;  2NUP B;  1TMW A;  2LXX A;  1Q8X A;  5KYY A;  3A5L S;  1SVQ A;  1T44 G;  5IVU A;  2FH3 A;  1P8Z G;  1DEJ S;  5A1M A;  2XFA A;  1NLV G;  5HVK D;  1VFQ A;  5KYY B;  1V6F A;  1X67 A;  1KCQ A;  3FFK A;  1AK7 A; 
#chains in the Genus database with same CATH topology
 3FFN A;  4CBW G;  1NM1 G;  1MDU A;  1TVJ A;  2VIK A;  1PD0 A;  1YAG G;  1SVY A;  1F7S A;  2FH2 A;  3CIP G;  3A5M S;  5HVK B;  4KEE A;  4PKH B;  5KYX A;  5FAE A;  1M2O A;  2LJ8 A;  2FGH A;  3EGX A;  1YVN G;  2KVK A;  4LIZ A;  2NUT A;  5KYX B;  1J72 A;  2HD7 A;  3EH1 A;  1WNJ A;  3A5N S;  3CI5 G;  3EGX B;  1SVR A;  1C0F S;  1COF A;  2L72 A;  4S10 C;  1D4X G;  2I2Q A;  1M2V A;  1QPV A;  2NUT B;  1M4J A;  4PKI G;  4CBU G;  3A5O S;  1PCX A;  1ESV S;  1EQY S;  1NPH A;  5KYW A;  3EFO A;  5DD2 A;  2D8B A;  4JD2 H;  1T3X A;  1D0N A;  1M2V B;  1VKK A;  1CFY A;  4CBX G;  5KYW B;  3EFO B;  2XF1 A;  5L6W C;  3Q2B A;  1UDM A;  1WM4 A;  3CJB G;  4PKG G;  4KEF A;  3EH2 A;  1T3Y A;  2MOT A;  1PD1 A;  4Z94 G;  2LLF A;  5KYU A;  1Q8G A;  3FG6 A;  2MV2 A;  2FH1 A;  4KED A;  3FG7 A;  3TU5 B;  3CJC G;  3EGD A;  1RGI G;  5KYN A;  2FH4 A;  1P8X A;  2QTV A;  2MP4 A;  1WFS A;  5KYU B;  1AK6 A;  2W0I A;  2VAC A;  3EGD B;  3DA7 A;  2FF3 A;  1H1V G;  5FAF A;  3EG9 A;  1JHW A;  1T2L A;  3DAW B;  1C0G S;  2NUP A;  1NMD G;  2VIL A;  1HQZ 1;  1CNU A;  2FF6 G;  3EG9 B;  3L50 A;  4BEX 1;  1AHQ A;  2NUP B;  1TMW A;  2LXX A;  1Q8X A;  5KYY A;  3A5L S;  1SVQ A;  1T44 G;  5IVU A;  2FH3 A;  1P8Z G;  1DEJ S;  5A1M A;  2XFA A;  1NLV G;  5HVK D;  1VFQ A;  5KYY B;  1V6F A;  1X67 A;  1KCQ A;  3FFK A;  1AK7 A; 
#chains in the Genus database with same CATH homology
 3FFN A;  4CBW G;  1NM1 G;  1MDU A;  1TVJ A;  2VIK A;  1PD0 A;  1YAG G;  1SVY A;  1F7S A;  2FH2 A;  3CIP G;  3A5M S;  5HVK B;  4KEE A;  4PKH B;  5KYX A;  5FAE A;  1M2O A;  2LJ8 A;  2FGH A;  3EGX A;  1YVN G;  2KVK A;  4LIZ A;  2NUT A;  5KYX B;  1J72 A;  2HD7 A;  3EH1 A;  1WNJ A;  3A5N S;  3CI5 G;  3EGX B;  1SVR A;  1C0F S;  1COF A;  2L72 A;  4S10 C;  1D4X G;  2I2Q A;  1M2V A;  1QPV A;  2NUT B;  1M4J A;  4PKI G;  4CBU G;  3A5O S;  1PCX A;  1ESV S;  1EQY S;  1NPH A;  5KYW A;  3EFO A;  5DD2 A;  2D8B A;  4JD2 H;  1T3X A;  1D0N A;  1M2V B;  1VKK A;  1CFY A;  4CBX G;  5KYW B;  3EFO B;  2XF1 A;  5L6W C;  3Q2B A;  1UDM A;  1WM4 A;  3CJB G;  4PKG G;  4KEF A;  3EH2 A;  1T3Y A;  2MOT A;  1PD1 A;  4Z94 G;  2LLF A;  5KYU A;  1Q8G A;  3FG6 A;  2MV2 A;  2FH1 A;  4KED A;  3FG7 A;  3TU5 B;  3CJC G;  3EGD A;  1RGI G;  5KYN A;  2FH4 A;  1P8X A;  2QTV A;  2MP4 A;  1WFS A;  5KYU B;  1AK6 A;  2W0I A;  2VAC A;  3EGD B;  3DA7 A;  2FF3 A;  1H1V G;  5FAF A;  3EG9 A;  1JHW A;  1T2L A;  3DAW B;  1C0G S;  2NUP A;  1NMD G;  2VIL A;  1HQZ 1;  1CNU A;  2FF6 G;  3EG9 B;  3L50 A;  4BEX 1;  1AHQ A;  2NUP B;  1TMW A;  2LXX A;  1Q8X A;  5KYY A;  3A5L S;  1SVQ A;  1T44 G;  5IVU A;  2FH3 A;  1P8Z G;  1DEJ S;  5A1M A;  2XFA A;  1NLV G;  5HVK D;  1VFQ A;  5KYY B;  1V6F A;  1X67 A;  1KCQ A;  3FFK A;  1AK7 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...