1WM4 | Genus

Total Genus 26

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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	26
sequence length	142
structure length	142
Chain Sequence	MATKIDKEACRAAYNLVRDDGSAVIWVTFRYDGATIVPGDQGADYQHFIQQCTDDVRLFAFVRFTTGDAMSKRSKFALITWIGEDVSGLQRAKTGTDKTLVKEVVQNFAKEFVISDRKELEEDFIRSELKKAGGANYDAQSE

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	Solution structure of coactosin reveals structural homology to ADF/cofilin family proteins pubmed doi rcsb
molecule keywords	Coactosin-like protein
molecule tags	Protein binding
source organism	Mus musculus
total genus	26
structure length	142
sequence length	142
ec nomenclature
pdb deposition date	2004-07-03

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00241	Cofilin_ADF	Cofilin/tropomyosin-type actin-binding protein

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.40.20.10	Alpha Beta	3-Layer(aba) Sandwich	Severin	Severin	1wm4A00

3CJCG 5DD2A 3EGDB 3TU5B 2LLFA 1C0FS 1M4JA 1P8XA 2I2QA 1VFQA 3EG9A 4PKIG 2W0IA 1M2OA 4PKHB 5HVKD 2NUPB 4LIZA 1T3YA 2LXXA 4KEDA 4S10C 1UDMA 1QPVA 1CNUA 1NLVG 4KEFA 2FH4A 1RGIG 2NUTB 3EGDA 2FGHA 1NMDG 1NPHA 5A1MA 5KYXB 1M2VB 1V6FA 2NUPA 4BEX1 3DAWB 1WFSA 1P8ZG 1WM4A 1SVYA 3EFOB 5KYYA 1WNJA 1TVJA 2NUTA 1PD0A 1AK6A 3A5MS 5L6WC 1HQZ1 5KYUA 1Q8XA 5KYYB 5KYXA 3A5OS 1M2VA 2MV2A 4JD2H 5HVKB 2MOTA 5KYUB 1DEJS 1H1VG 2VACA 1VKKA 1YVNG 3FFNA 3FG6A 1F7SA 3EFOA 1AHQA 2QTVA 5IVUA 2XFAA 2XF1A 3CJBG 5FAEA 2FH2A 3L50A 1JHWA 1TMWA 2FH3A 3EGXB 4PKGG 1PD1A 2D8BA 1J72A 1T2LA 1D0NA 1YAGG 2VILA 1NM1G 1ESVS 2FH1A 1Q8GA 1SVRA 3FG7A 3CI5G 2FF3A 5KYWB 2LJ8A 1COFA 2FF6G 3EGXA 1CFYA 3EH2A 1MDUA 1PCXA 2L72A 3FFKA 4KEEA 2VIKA 4CBUG 1D4XG 1KCQA 3A5LS 3EG9B 1T44G 2HD7A 4CBWG 4CBXG 1AK7A 1T3XA 5FAFA 2KVKA 4Z94G 3CIPG 5KYNA 3Q2BA 1EQYS 1X67A 3EH1A 1C0GS 2MP4A 3A5NS 1SVQA 5KYWA
chains in the Genus database with same CATH superfamily

3CJCG 5DD2A 3EGDB 3TU5B 2LLFA 1C0FS 1M4JA 1P8XA 3DA7A 2I2QA 1VFQA 3EG9A 4PKIG 2W0IA 1M2OA 4PKHB 5HVKD 2NUPB 4LIZA 1T3YA 2LXXA 4KEDA 4S10C 1UDMA 1QPVA 1CNUA 1NLVG 4KEFA 2FH4A 1RGIG 2NUTB 3EGDA 2FGHA 1NMDG 1NPHA 5A1MA 5KYXB 1M2VB 1V6FA 2NUPA 4BEX1 3DAWB 1WFSA 1P8ZG 1WM4A 1SVYA 3EFOB 5KYYA 1WNJA 1TVJA 2NUTA 1PD0A 1AK6A 3A5MS 5L6WC 1HQZ1 5KYUA 1Q8XA 5KYYB 5KYXA 3A5OS 1M2VA 2MV2A 4JD2H 5HVKB 2MOTA 5KYUB 1DEJS 1H1VG 2VACA 1VKKA 1YVNG 3FFNA 3FG6A 1F7SA 3EFOA 1AHQA 2QTVA 5IVUA 2XFAA 2XF1A 3CJBG 5FAEA 2FH2A 3L50A 1JHWA 1TMWA 2FH3A 3EGXB 4PKGG 1PD1A 2D8BA 1J72A 1T2LA 1D0NA 1YAGG 2VILA 1NM1G 1ESVS 2FH1A 1Q8GA 1SVRA 3FG7A 3CI5G 2FF3A 5KYWB 2LJ8A 1COFA 2FF6G 3EGXA 1CFYA 3EH2A 1MDUA 1PCXA 2L72A 3FFKA 4KEEA 2VIKA 4CBUG 1D4XG 1KCQA 3A5LS 3EG9B 1T44G 2HD7A 4CBWG 4CBXG 1AK7A 1T3XA 5FAFA 2KVKA 4Z94G 3CIPG 5KYNA 3Q2BA 1EQYS 1X67A 3EH1A 1C0GS 2MP4A 3A5NS 1SVQA 5KYWA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 3CJC G;  5DD2 A;  3EGD B;  3TU5 B;  2LLF A;  1C0F S;  1M4J A;  1P8X A;  2I2Q A;  1VFQ A;  3EG9 A;  4PKI G;  2W0I A;  1M2O A;  4PKH B;  5HVK D;  2NUP B;  4LIZ A;  1T3Y A;  2LXX A;  4KED A;  4S10 C;  1UDM A;  1QPV A;  1CNU A;  1NLV G;  4KEF A;  2FH4 A;  1RGI G;  2NUT B;  3EGD A;  2FGH A;  1NMD G;  1NPH A;  5A1M A;  5KYX B;  1M2V B;  1V6F A;  2NUP A;  4BEX 1;  3DAW B;  1WFS A;  1P8Z G;  1WM4 A;  1SVY A;  3EFO B;  5KYY A;  1WNJ A;  1TVJ A;  2NUT A;  1PD0 A;  1AK6 A;  3A5M S;  5L6W C;  1HQZ 1;  5KYU A;  1Q8X A;  5KYY B;  5KYX A;  3A5O S;  1M2V A;  2MV2 A;  4JD2 H;  5HVK B;  2MOT A;  5KYU B;  1DEJ S;  1H1V G;  2VAC A;  1VKK A;  1YVN G;  3FFN A;  3FG6 A;  1F7S A;  3EFO A;  1AHQ A;  2QTV A;  5IVU A;  2XFA A;  2XF1 A;  3CJB G;  5FAE A;  2FH2 A;  3L50 A;  1JHW A;  1TMW A;  2FH3 A;  3EGX B;  4PKG G;  1PD1 A;  2D8B A;  1J72 A;  1T2L A;  1D0N A;  1YAG G;  2VIL A;  1NM1 G;  1ESV S;  2FH1 A;  1Q8G A;  1SVR A;  3FG7 A;  3CI5 G;  2FF3 A;  5KYW B;  2LJ8 A;  1COF A;  2FF6 G;  3EGX A;  1CFY A;  3EH2 A;  1MDU A;  1PCX A;  2L72 A;  3FFK A;  4KEE A;  2VIK A;  4CBU G;  1D4X G;  1KCQ A;  3A5L S;  3EG9 B;  1T44 G;  2HD7 A;  4CBW G;  4CBX G;  1AK7 A;  1T3X A;  5FAF A;  2KVK A;  4Z94 G;  3CIP G;  5KYN A;  3Q2B A;  1EQY S;  1X67 A;  3EH1 A;  1C0G S;  2MP4 A;  3A5N S;  1SVQ A;  5KYW A; 
#chains in the Genus database with same CATH topology
 3CJC G;  5DD2 A;  3EGD B;  3TU5 B;  2LLF A;  1C0F S;  1M4J A;  1P8X A;  3DA7 A;  2I2Q A;  1VFQ A;  3EG9 A;  4PKI G;  2W0I A;  1M2O A;  4PKH B;  5HVK D;  2NUP B;  4LIZ A;  1T3Y A;  2LXX A;  4KED A;  4S10 C;  1UDM A;  1QPV A;  1CNU A;  1NLV G;  4KEF A;  2FH4 A;  1RGI G;  2NUT B;  3EGD A;  2FGH A;  1NMD G;  1NPH A;  5A1M A;  5KYX B;  1M2V B;  1V6F A;  2NUP A;  4BEX 1;  3DAW B;  1WFS A;  1P8Z G;  1WM4 A;  1SVY A;  3EFO B;  5KYY A;  1WNJ A;  1TVJ A;  2NUT A;  1PD0 A;  1AK6 A;  3A5M S;  5L6W C;  1HQZ 1;  5KYU A;  1Q8X A;  5KYY B;  5KYX A;  3A5O S;  1M2V A;  2MV2 A;  4JD2 H;  5HVK B;  2MOT A;  5KYU B;  1DEJ S;  1H1V G;  2VAC A;  1VKK A;  1YVN G;  3FFN A;  3FG6 A;  1F7S A;  3EFO A;  1AHQ A;  2QTV A;  5IVU A;  2XFA A;  2XF1 A;  3CJB G;  5FAE A;  2FH2 A;  3L50 A;  1JHW A;  1TMW A;  2FH3 A;  3EGX B;  4PKG G;  1PD1 A;  2D8B A;  1J72 A;  1T2L A;  1D0N A;  1YAG G;  2VIL A;  1NM1 G;  1ESV S;  2FH1 A;  1Q8G A;  1SVR A;  3FG7 A;  3CI5 G;  2FF3 A;  5KYW B;  2LJ8 A;  1COF A;  2FF6 G;  3EGX A;  1CFY A;  3EH2 A;  1MDU A;  1PCX A;  2L72 A;  3FFK A;  4KEE A;  2VIK A;  4CBU G;  1D4X G;  1KCQ A;  3A5L S;  3EG9 B;  1T44 G;  2HD7 A;  4CBW G;  4CBX G;  1AK7 A;  1T3X A;  5FAF A;  2KVK A;  4Z94 G;  3CIP G;  5KYN A;  3Q2B A;  1EQY S;  1X67 A;  3EH1 A;  1C0G S;  2MP4 A;  3A5N S;  1SVQ A;  5KYW A; 
#chains in the Genus database with same CATH homology
 3CJC G;  5DD2 A;  3EGD B;  3TU5 B;  2LLF A;  1C0F S;  1M4J A;  1P8X A;  3DA7 A;  2I2Q A;  1VFQ A;  3EG9 A;  4PKI G;  2W0I A;  1M2O A;  4PKH B;  5HVK D;  2NUP B;  4LIZ A;  1T3Y A;  2LXX A;  4KED A;  4S10 C;  1UDM A;  1QPV A;  1CNU A;  1NLV G;  4KEF A;  2FH4 A;  1RGI G;  2NUT B;  3EGD A;  2FGH A;  1NMD G;  1NPH A;  5A1M A;  5KYX B;  1M2V B;  1V6F A;  2NUP A;  4BEX 1;  3DAW B;  1WFS A;  1P8Z G;  1WM4 A;  1SVY A;  3EFO B;  5KYY A;  1WNJ A;  1TVJ A;  2NUT A;  1PD0 A;  1AK6 A;  3A5M S;  5L6W C;  1HQZ 1;  5KYU A;  1Q8X A;  5KYY B;  5KYX A;  3A5O S;  1M2V A;  2MV2 A;  4JD2 H;  5HVK B;  2MOT A;  5KYU B;  1DEJ S;  1H1V G;  2VAC A;  1VKK A;  1YVN G;  3FFN A;  3FG6 A;  1F7S A;  3EFO A;  1AHQ A;  2QTV A;  5IVU A;  2XFA A;  2XF1 A;  3CJB G;  5FAE A;  2FH2 A;  3L50 A;  1JHW A;  1TMW A;  2FH3 A;  3EGX B;  4PKG G;  1PD1 A;  2D8B A;  1J72 A;  1T2L A;  1D0N A;  1YAG G;  2VIL A;  1NM1 G;  1ESV S;  2FH1 A;  1Q8G A;  1SVR A;  3FG7 A;  3CI5 G;  2FF3 A;  5KYW B;  2LJ8 A;  1COF A;  2FF6 G;  3EGX A;  1CFY A;  3EH2 A;  1MDU A;  1PCX A;  2L72 A;  3FFK A;  4KEE A;  2VIK A;  4CBU G;  1D4X G;  1KCQ A;  3A5L S;  3EG9 B;  1T44 G;  2HD7 A;  4CBW G;  4CBX G;  1AK7 A;  1T3X A;  5FAF A;  2KVK A;  4Z94 G;  3CIP G;  5KYN A;  3Q2B A;  1EQY S;  1X67 A;  3EH1 A;  1C0G S;  2MP4 A;  3A5N S;  1SVQ A;  5KYW A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

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#similar chains, but unknotted
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1WM4A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations