1WM4A

Solution structure of mouse coactosin, an actin filament binding protein
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
142
structure length
142
Chain Sequence
MATKIDKEACRAAYNLVRDDGSAVIWVTFRYDGATIVPGDQGADYQHFIQQCTDDVRLFAFVRFTTGDAMSKRSKFALITWIGEDVSGLQRAKTGTDKTLVKEVVQNFAKEFVISDRKELEEDFIRSELKKAGGANYDAQSE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of coactosin reveals structural homology to ADF/cofilin family proteins
pubmed doi rcsb
molecule tags Protein binding
source organism Mus musculus
molecule keywords Coactosin-like protein
total genus 26
structure length 142
sequence length 142
ec nomenclature
pdb deposition date 2004-07-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00241 Cofilin_ADF Cofilin/tropomyosin-type actin-binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 1wm4A00
1D0NA 1SVRA 1X67A 2VILA 1PD0A 4PKHB 4Z94G 1D4XG 1Q8GA 1VFQA 1NMDG 2QTVA 2XFAA 1VKKA 1WFSA 3EG9A 1AK6A 5KYUA 1M2OA 4KEFA 1EQYS 3DAWB 3EGDB 4PKIG 5HVKB 2XF1A 1WNJA 1SVYA 5L6WC 2VACA 3EFOA 2HD7A 5KYWA 3L50A 3FG7A 5FAFA 3EH2A 1DEJS 2NUPA 2L72A 1TMWA 1V6FA 2LJ8A 1KCQA 5A1MA 5KYYA 5KYNA 1C0GS 5KYYB 2FH3A 1AHQA 1P8ZG 1T44G 1Q8XA 2MP4A 1COFA 2LXXA 3EG9B 1NM1G 5KYUB 1P8XA 1MDUA 3CI5G 3CIPG 1TVJA 2NUTA 2MV2A 4CBUG 2NUTB 3EH1A 3EFOB 1T2LA 1AK7A 1PD1A 5KYWB 4CBWG 1UDMA 2D8BA 1T3XA 2MOTA 4LIZA 1YVNG 2I2QA 2FH1A 2NUPB 2W0IA 3FG6A 4S10C 4CBXG 3Q2BA 1F7SA 3TU5B 3A5NS 2FF6G 3A5OS 2LLFA 3CJCG 3FFKA 5DD2A 1YAGG 1H1VG 1M4JA 3FFNA 1NPHA 4JD2H 5IVUA 5KYXA 1PCXA 1RGIG 5KYXB 1J72A 1SVQA 2FH2A 4KEDA 5HVKD 3A5MS 3EGXA 1HQZ1 1NLVG 3EGXB 1ESVS 5FAEA 1QPVA 3EGDA 4KEEA 3CJBG 4PKGG 1M2VA 2FGHA 2FF3A 2KVKA 1M2VB 1WM4A 1CFYA 1T3YA 1JHWA 3A5LS 1CNUA 4BEX1 2FH4A 2VIKA 1C0FS
chains in the Genus database with same CATH superfamily
1D0NA 1SVRA 1X67A 2VILA 1PD0A 4PKHB 4Z94G 1D4XG 1Q8GA 1VFQA 1NMDG 2QTVA 2XFAA 1VKKA 1WFSA 3EG9A 1AK6A 5KYUA 1M2OA 4KEFA 1EQYS 3DAWB 3EGDB 4PKIG 5HVKB 2XF1A 1WNJA 1SVYA 5L6WC 2VACA 3EFOA 2HD7A 5KYWA 3L50A 3FG7A 5FAFA 3EH2A 1DEJS 2NUPA 2L72A 1TMWA 1V6FA 2LJ8A 1KCQA 5A1MA 5KYYA 5KYNA 1C0GS 5KYYB 2FH3A 1AHQA 1P8ZG 1T44G 1Q8XA 2MP4A 1COFA 2LXXA 3EG9B 1NM1G 5KYUB 1P8XA 1MDUA 3CI5G 3CIPG 1TVJA 2NUTA 2MV2A 4CBUG 2NUTB 3EH1A 3DA7A 3EFOB 1T2LA 1AK7A 1PD1A 5KYWB 4CBWG 1UDMA 2D8BA 1T3XA 2MOTA 4LIZA 1YVNG 2I2QA 2FH1A 2NUPB 2W0IA 3FG6A 4S10C 4CBXG 3Q2BA 1F7SA 3TU5B 3A5NS 2FF6G 3A5OS 2LLFA 3CJCG 3FFKA 5DD2A 1YAGG 1H1VG 1M4JA 3FFNA 1NPHA 4JD2H 5IVUA 5KYXA 1PCXA 1RGIG 5KYXB 1J72A 1SVQA 2FH2A 4KEDA 5HVKD 3A5MS 3EGXA 1HQZ1 1NLVG 3EGXB 1ESVS 5FAEA 1QPVA 3EGDA 4KEEA 3CJBG 4PKGG 1M2VA 2FGHA 2FF3A 2KVKA 1M2VB 1WM4A 1CFYA 1T3YA 1JHWA 3A5LS 1CNUA 4BEX1 2FH4A 2VIKA 1C0FS
chains in the Genus database with same CATH topology
1D0NA 1SVRA 1X67A 2VILA 1PD0A 4PKHB 4Z94G 1D4XG 1Q8GA 1VFQA 1NMDG 2QTVA 2XFAA 1VKKA 1WFSA 3EG9A 1AK6A 5KYUA 1M2OA 4KEFA 1EQYS 3DAWB 3EGDB 4PKIG 5HVKB 2XF1A 1WNJA 1SVYA 5L6WC 2VACA 3EFOA 2HD7A 5KYWA 3L50A 3FG7A 5FAFA 3EH2A 1DEJS 2NUPA 2L72A 1TMWA 1V6FA 2LJ8A 1KCQA 5A1MA 5KYYA 5KYNA 1C0GS 5KYYB 2FH3A 1AHQA 1P8ZG 1T44G 1Q8XA 2MP4A 1COFA 2LXXA 3EG9B 1NM1G 5KYUB 1P8XA 1MDUA 3CI5G 3CIPG 1TVJA 2NUTA 2MV2A 4CBUG 2NUTB 3EH1A 3DA7A 3EFOB 1T2LA 1AK7A 1PD1A 5KYWB 4CBWG 1UDMA 2D8BA 1T3XA 2MOTA 4LIZA 1YVNG 2I2QA 2FH1A 2NUPB 2W0IA 3FG6A 4S10C 4CBXG 3Q2BA 1F7SA 3TU5B 3A5NS 2FF6G 3A5OS 2LLFA 3CJCG 3FFKA 5DD2A 1YAGG 1H1VG 1M4JA 3FFNA 1NPHA 4JD2H 5IVUA 5KYXA 1PCXA 1RGIG 5KYXB 1J72A 1SVQA 2FH2A 4KEDA 5HVKD 3A5MS 3EGXA 1HQZ1 1NLVG 3EGXB 1ESVS 5FAEA 1QPVA 3EGDA 4KEEA 3CJBG 4PKGG 1M2VA 2FGHA 2FF3A 2KVKA 1M2VB 1WM4A 1CFYA 1T3YA 1JHWA 3A5LS 1CNUA 4BEX1 2FH4A 2VIKA 1C0FS
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1D0N A;  1SVR A;  1X67 A;  2VIL A;  1PD0 A;  4PKH B;  4Z94 G;  1D4X G;  1Q8G A;  1VFQ A;  1NMD G;  2QTV A;  2XFA A;  1VKK A;  1WFS A;  3EG9 A;  1AK6 A;  5KYU A;  1M2O A;  4KEF A;  1EQY S;  3DAW B;  3EGD B;  4PKI G;  5HVK B;  2XF1 A;  1WNJ A;  1SVY A;  5L6W C;  2VAC A;  3EFO A;  2HD7 A;  5KYW A;  3L50 A;  3FG7 A;  5FAF A;  3EH2 A;  1DEJ S;  2NUP A;  2L72 A;  1TMW A;  1V6F A;  2LJ8 A;  1KCQ A;  5A1M A;  5KYY A;  5KYN A;  1C0G S;  5KYY B;  2FH3 A;  1AHQ A;  1P8Z G;  1T44 G;  1Q8X A;  2MP4 A;  1COF A;  2LXX A;  3EG9 B;  1NM1 G;  5KYU B;  1P8X A;  1MDU A;  3CI5 G;  3CIP G;  1TVJ A;  2NUT A;  2MV2 A;  4CBU G;  2NUT B;  3EH1 A;  3EFO B;  1T2L A;  1AK7 A;  1PD1 A;  5KYW B;  4CBW G;  1UDM A;  2D8B A;  1T3X A;  2MOT A;  4LIZ A;  1YVN G;  2I2Q A;  2FH1 A;  2NUP B;  2W0I A;  3FG6 A;  4S10 C;  4CBX G;  3Q2B A;  1F7S A;  3TU5 B;  3A5N S;  2FF6 G;  3A5O S;  2LLF A;  3CJC G;  3FFK A;  5DD2 A;  1YAG G;  1H1V G;  1M4J A;  3FFN A;  1NPH A;  4JD2 H;  5IVU A;  5KYX A;  1PCX A;  1RGI G;  5KYX B;  1J72 A;  1SVQ A;  2FH2 A;  4KED A;  5HVK D;  3A5M S;  3EGX A;  1HQZ 1;  1NLV G;  3EGX B;  1ESV S;  5FAE A;  1QPV A;  3EGD A;  4KEE A;  3CJB G;  4PKG G;  1M2V A;  2FGH A;  2FF3 A;  2KVK A;  1M2V B;  1WM4 A;  1CFY A;  1T3Y A;  1JHW A;  3A5L S;  1CNU A;  4BEX 1;  2FH4 A;  2VIK A;  1C0F S; 
#chains in the Genus database with same CATH topology
 1D0N A;  1SVR A;  1X67 A;  2VIL A;  1PD0 A;  4PKH B;  4Z94 G;  1D4X G;  1Q8G A;  1VFQ A;  1NMD G;  2QTV A;  2XFA A;  1VKK A;  1WFS A;  3EG9 A;  1AK6 A;  5KYU A;  1M2O A;  4KEF A;  1EQY S;  3DAW B;  3EGD B;  4PKI G;  5HVK B;  2XF1 A;  1WNJ A;  1SVY A;  5L6W C;  2VAC A;  3EFO A;  2HD7 A;  5KYW A;  3L50 A;  3FG7 A;  5FAF A;  3EH2 A;  1DEJ S;  2NUP A;  2L72 A;  1TMW A;  1V6F A;  2LJ8 A;  1KCQ A;  5A1M A;  5KYY A;  5KYN A;  1C0G S;  5KYY B;  2FH3 A;  1AHQ A;  1P8Z G;  1T44 G;  1Q8X A;  2MP4 A;  1COF A;  2LXX A;  3EG9 B;  1NM1 G;  5KYU B;  1P8X A;  1MDU A;  3CI5 G;  3CIP G;  1TVJ A;  2NUT A;  2MV2 A;  4CBU G;  2NUT B;  3EH1 A;  3DA7 A;  3EFO B;  1T2L A;  1AK7 A;  1PD1 A;  5KYW B;  4CBW G;  1UDM A;  2D8B A;  1T3X A;  2MOT A;  4LIZ A;  1YVN G;  2I2Q A;  2FH1 A;  2NUP B;  2W0I A;  3FG6 A;  4S10 C;  4CBX G;  3Q2B A;  1F7S A;  3TU5 B;  3A5N S;  2FF6 G;  3A5O S;  2LLF A;  3CJC G;  3FFK A;  5DD2 A;  1YAG G;  1H1V G;  1M4J A;  3FFN A;  1NPH A;  4JD2 H;  5IVU A;  5KYX A;  1PCX A;  1RGI G;  5KYX B;  1J72 A;  1SVQ A;  2FH2 A;  4KED A;  5HVK D;  3A5M S;  3EGX A;  1HQZ 1;  1NLV G;  3EGX B;  1ESV S;  5FAE A;  1QPV A;  3EGD A;  4KEE A;  3CJB G;  4PKG G;  1M2V A;  2FGH A;  2FF3 A;  2KVK A;  1M2V B;  1WM4 A;  1CFY A;  1T3Y A;  1JHW A;  3A5L S;  1CNU A;  4BEX 1;  2FH4 A;  2VIK A;  1C0F S; 
#chains in the Genus database with same CATH homology
 1D0N A;  1SVR A;  1X67 A;  2VIL A;  1PD0 A;  4PKH B;  4Z94 G;  1D4X G;  1Q8G A;  1VFQ A;  1NMD G;  2QTV A;  2XFA A;  1VKK A;  1WFS A;  3EG9 A;  1AK6 A;  5KYU A;  1M2O A;  4KEF A;  1EQY S;  3DAW B;  3EGD B;  4PKI G;  5HVK B;  2XF1 A;  1WNJ A;  1SVY A;  5L6W C;  2VAC A;  3EFO A;  2HD7 A;  5KYW A;  3L50 A;  3FG7 A;  5FAF A;  3EH2 A;  1DEJ S;  2NUP A;  2L72 A;  1TMW A;  1V6F A;  2LJ8 A;  1KCQ A;  5A1M A;  5KYY A;  5KYN A;  1C0G S;  5KYY B;  2FH3 A;  1AHQ A;  1P8Z G;  1T44 G;  1Q8X A;  2MP4 A;  1COF A;  2LXX A;  3EG9 B;  1NM1 G;  5KYU B;  1P8X A;  1MDU A;  3CI5 G;  3CIP G;  1TVJ A;  2NUT A;  2MV2 A;  4CBU G;  2NUT B;  3EH1 A;  3DA7 A;  3EFO B;  1T2L A;  1AK7 A;  1PD1 A;  5KYW B;  4CBW G;  1UDM A;  2D8B A;  1T3X A;  2MOT A;  4LIZ A;  1YVN G;  2I2Q A;  2FH1 A;  2NUP B;  2W0I A;  3FG6 A;  4S10 C;  4CBX G;  3Q2B A;  1F7S A;  3TU5 B;  3A5N S;  2FF6 G;  3A5O S;  2LLF A;  3CJC G;  3FFK A;  5DD2 A;  1YAG G;  1H1V G;  1M4J A;  3FFN A;  1NPH A;  4JD2 H;  5IVU A;  5KYX A;  1PCX A;  1RGI G;  5KYX B;  1J72 A;  1SVQ A;  2FH2 A;  4KED A;  5HVK D;  3A5M S;  3EGX A;  1HQZ 1;  1NLV G;  3EGX B;  1ESV S;  5FAE A;  1QPV A;  3EGD A;  4KEE A;  3CJB G;  4PKG G;  1M2V A;  2FGH A;  2FF3 A;  2KVK A;  1M2V B;  1WM4 A;  1CFY A;  1T3Y A;  1JHW A;  3A5L S;  1CNU A;  4BEX 1;  2FH4 A;  2VIK A;  1C0F S; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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