1X67A

Solution structure of the cofilin homology domain of hip-55 (drebrin-like protein)
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
146
structure length
146
Chain Sequence
GSSGSSGMAANLSRNGPALQEAYVRVVTEKSPTDWALFTYEGNSNDIRVAGTGEGGLEEMVEELNSGKVMYAFCRVKDPNSGLPKFVLINWTGEGVNDVRKGACASHVSTMASFLKGAHVTINARAEEDVEPECIMEKVASGPSSG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title NMR solution structures of actin depolymerizing factor homology domains.
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Drebrin-like protein
total genus 21
structure length 146
sequence length 146
ec nomenclature
pdb deposition date 2005-05-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00241 Cofilin_ADF Cofilin/tropomyosin-type actin-binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 1x67A01
2MV2A 3EG9B 2KVKA 1F7SA 1M2OA 5KYUB 1NMDG 5L6WC 5KYXA 1RGIG 1YAGG 3EGDA 4JD2H 5KYYB 4KEDA 1CNUA 3EFOA 1PD1A 2XFAA 2NUTA 1M4JA 1AHQA 3EGXA 2W0IA 2QTVA 1EQYS 5FAFA 1HQZ1 2NUPB 2LXXA 3Q2BA 4KEEA 2FF6G 2VILA 5HVKB 5KYWB 1AK6A 1T3YA 3FG7A 1YVNG 1NM1G 5IVUA 1WFSA 3A5LS 3EG9A 3CJBG 1UDMA 5DD2A 1COFA 1T44G 1KCQA 1Q8XA 1DEJS 4BEX1 3EH2A 1WM4A 4PKGG 3CI5G 1M2VB 5KYNA 3CJCG 1C0GS 1PD0A 2HD7A 5KYWA 1WNJA 1VKKA 5KYXB 2LLFA 3FFKA 1AK7A 1D0NA 2D8BA 2L72A 3TU5B 1TMWA 1MDUA 5KYUA 3EGXB 1T2LA 1V6FA 1H1VG 2MOTA 5KYYA 4PKIG 1P8ZG 5HVKD 1ESVS 1SVYA 2MP4A 4CBWG 4CBXG 2FH3A 2VIKA 2XF1A 3A5MS 2LJ8A 1M2VA 1P8XA 1C0FS 2NUPA 2FF3A 3CIPG 3A5OS 1CFYA 4KEFA 3EGDB 2FH1A 3L50A 4CBUG 3A5NS 3FG6A 3EFOB 1NPHA 1QPVA 2FH4A 2NUTB 2FH2A 1JHWA 1SVRA 5A1MA 3DAWB 4S10C 1VFQA 1NLVG 2VACA 4LIZA 1SVQA 1J72A 2FGHA 3EH1A 1X67A 1TVJA 2I2QA 5FAEA 4PKHB 1T3XA 1Q8GA 1PCXA 4Z94G 3FFNA 1D4XG
chains in the Genus database with same CATH superfamily
2MV2A 3EG9B 2KVKA 1F7SA 1M2OA 5KYUB 1NMDG 5L6WC 5KYXA 1RGIG 1YAGG 3EGDA 4JD2H 5KYYB 4KEDA 1CNUA 3EFOA 1PD1A 2XFAA 2NUTA 1M4JA 1AHQA 3EGXA 2W0IA 2QTVA 1EQYS 5FAFA 1HQZ1 2NUPB 2LXXA 3Q2BA 4KEEA 2FF6G 2VILA 5HVKB 5KYWB 1AK6A 1T3YA 3FG7A 1YVNG 1NM1G 5IVUA 1WFSA 3A5LS 3EG9A 3CJBG 1UDMA 5DD2A 1COFA 1T44G 1KCQA 1Q8XA 1DEJS 4BEX1 3EH2A 1WM4A 4PKGG 3CI5G 1M2VB 5KYNA 3CJCG 1C0GS 1PD0A 2HD7A 5KYWA 1WNJA 1VKKA 5KYXB 2LLFA 3FFKA 1AK7A 1D0NA 2D8BA 2L72A 3TU5B 1TMWA 1MDUA 5KYUA 3EGXB 1T2LA 1V6FA 1H1VG 2MOTA 5KYYA 4PKIG 1P8ZG 5HVKD 1ESVS 1SVYA 2MP4A 4CBWG 4CBXG 2FH3A 2VIKA 2XF1A 3A5MS 2LJ8A 3DA7A 1M2VA 1P8XA 1C0FS 2NUPA 2FF3A 3CIPG 3A5OS 1CFYA 4KEFA 3EGDB 2FH1A 3L50A 4CBUG 3A5NS 3FG6A 3EFOB 1NPHA 1QPVA 2FH4A 2NUTB 2FH2A 1JHWA 1SVRA 5A1MA 3DAWB 4S10C 1VFQA 1NLVG 2VACA 4LIZA 1SVQA 1J72A 2FGHA 3EH1A 1X67A 1TVJA 2I2QA 5FAEA 4PKHB 1T3XA 1Q8GA 1PCXA 4Z94G 3FFNA 1D4XG
chains in the Genus database with same CATH topology
2MV2A 3EG9B 2KVKA 1F7SA 1M2OA 5KYUB 1NMDG 5L6WC 5KYXA 1RGIG 1YAGG 3EGDA 4JD2H 5KYYB 4KEDA 1CNUA 3EFOA 1PD1A 2XFAA 2NUTA 1M4JA 1AHQA 3EGXA 2W0IA 2QTVA 1EQYS 5FAFA 1HQZ1 2NUPB 2LXXA 3Q2BA 4KEEA 2FF6G 2VILA 5HVKB 5KYWB 1AK6A 1T3YA 3FG7A 1YVNG 1NM1G 5IVUA 1WFSA 3A5LS 3EG9A 3CJBG 1UDMA 5DD2A 1COFA 1T44G 1KCQA 1Q8XA 1DEJS 4BEX1 3EH2A 1WM4A 4PKGG 3CI5G 1M2VB 5KYNA 3CJCG 1C0GS 1PD0A 2HD7A 5KYWA 1WNJA 1VKKA 5KYXB 2LLFA 3FFKA 1AK7A 1D0NA 2D8BA 2L72A 3TU5B 1TMWA 1MDUA 5KYUA 3EGXB 1T2LA 1V6FA 1H1VG 2MOTA 5KYYA 4PKIG 1P8ZG 5HVKD 1ESVS 1SVYA 2MP4A 4CBWG 4CBXG 2FH3A 2VIKA 2XF1A 3A5MS 2LJ8A 3DA7A 1M2VA 1P8XA 1C0FS 2NUPA 2FF3A 3CIPG 3A5OS 1CFYA 4KEFA 3EGDB 2FH1A 3L50A 4CBUG 3A5NS 3FG6A 3EFOB 1NPHA 1QPVA 2FH4A 2NUTB 2FH2A 1JHWA 1SVRA 5A1MA 3DAWB 4S10C 1VFQA 1NLVG 2VACA 4LIZA 1SVQA 1J72A 2FGHA 3EH1A 1X67A 1TVJA 2I2QA 5FAEA 4PKHB 1T3XA 1Q8GA 1PCXA 4Z94G 3FFNA 1D4XG
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2MV2 A;  3EG9 B;  2KVK A;  1F7S A;  1M2O A;  5KYU B;  1NMD G;  5L6W C;  5KYX A;  1RGI G;  1YAG G;  3EGD A;  4JD2 H;  5KYY B;  4KED A;  1CNU A;  3EFO A;  1PD1 A;  2XFA A;  2NUT A;  1M4J A;  1AHQ A;  3EGX A;  2W0I A;  2QTV A;  1EQY S;  5FAF A;  1HQZ 1;  2NUP B;  2LXX A;  3Q2B A;  4KEE A;  2FF6 G;  2VIL A;  5HVK B;  5KYW B;  1AK6 A;  1T3Y A;  3FG7 A;  1YVN G;  1NM1 G;  5IVU A;  1WFS A;  3A5L S;  3EG9 A;  3CJB G;  1UDM A;  5DD2 A;  1COF A;  1T44 G;  1KCQ A;  1Q8X A;  1DEJ S;  4BEX 1;  3EH2 A;  1WM4 A;  4PKG G;  3CI5 G;  1M2V B;  5KYN A;  3CJC G;  1C0G S;  1PD0 A;  2HD7 A;  5KYW A;  1WNJ A;  1VKK A;  5KYX B;  2LLF A;  3FFK A;  1AK7 A;  1D0N A;  2D8B A;  2L72 A;  3TU5 B;  1TMW A;  1MDU A;  5KYU A;  3EGX B;  1T2L A;  1V6F A;  1H1V G;  2MOT A;  5KYY A;  4PKI G;  1P8Z G;  5HVK D;  1ESV S;  1SVY A;  2MP4 A;  4CBW G;  4CBX G;  2FH3 A;  2VIK A;  2XF1 A;  3A5M S;  2LJ8 A;  1M2V A;  1P8X A;  1C0F S;  2NUP A;  2FF3 A;  3CIP G;  3A5O S;  1CFY A;  4KEF A;  3EGD B;  2FH1 A;  3L50 A;  4CBU G;  3A5N S;  3FG6 A;  3EFO B;  1NPH A;  1QPV A;  2FH4 A;  2NUT B;  2FH2 A;  1JHW A;  1SVR A;  5A1M A;  3DAW B;  4S10 C;  1VFQ A;  1NLV G;  2VAC A;  4LIZ A;  1SVQ A;  1J72 A;  2FGH A;  3EH1 A;  1X67 A;  1TVJ A;  2I2Q A;  5FAE A;  4PKH B;  1T3X A;  1Q8G A;  1PCX A;  4Z94 G;  3FFN A;  1D4X G; 
#chains in the Genus database with same CATH topology
 2MV2 A;  3EG9 B;  2KVK A;  1F7S A;  1M2O A;  5KYU B;  1NMD G;  5L6W C;  5KYX A;  1RGI G;  1YAG G;  3EGD A;  4JD2 H;  5KYY B;  4KED A;  1CNU A;  3EFO A;  1PD1 A;  2XFA A;  2NUT A;  1M4J A;  1AHQ A;  3EGX A;  2W0I A;  2QTV A;  1EQY S;  5FAF A;  1HQZ 1;  2NUP B;  2LXX A;  3Q2B A;  4KEE A;  2FF6 G;  2VIL A;  5HVK B;  5KYW B;  1AK6 A;  1T3Y A;  3FG7 A;  1YVN G;  1NM1 G;  5IVU A;  1WFS A;  3A5L S;  3EG9 A;  3CJB G;  1UDM A;  5DD2 A;  1COF A;  1T44 G;  1KCQ A;  1Q8X A;  1DEJ S;  4BEX 1;  3EH2 A;  1WM4 A;  4PKG G;  3CI5 G;  1M2V B;  5KYN A;  3CJC G;  1C0G S;  1PD0 A;  2HD7 A;  5KYW A;  1WNJ A;  1VKK A;  5KYX B;  2LLF A;  3FFK A;  1AK7 A;  1D0N A;  2D8B A;  2L72 A;  3TU5 B;  1TMW A;  1MDU A;  5KYU A;  3EGX B;  1T2L A;  1V6F A;  1H1V G;  2MOT A;  5KYY A;  4PKI G;  1P8Z G;  5HVK D;  1ESV S;  1SVY A;  2MP4 A;  4CBW G;  4CBX G;  2FH3 A;  2VIK A;  2XF1 A;  3A5M S;  2LJ8 A;  3DA7 A;  1M2V A;  1P8X A;  1C0F S;  2NUP A;  2FF3 A;  3CIP G;  3A5O S;  1CFY A;  4KEF A;  3EGD B;  2FH1 A;  3L50 A;  4CBU G;  3A5N S;  3FG6 A;  3EFO B;  1NPH A;  1QPV A;  2FH4 A;  2NUT B;  2FH2 A;  1JHW A;  1SVR A;  5A1M A;  3DAW B;  4S10 C;  1VFQ A;  1NLV G;  2VAC A;  4LIZ A;  1SVQ A;  1J72 A;  2FGH A;  3EH1 A;  1X67 A;  1TVJ A;  2I2Q A;  5FAE A;  4PKH B;  1T3X A;  1Q8G A;  1PCX A;  4Z94 G;  3FFN A;  1D4X G; 
#chains in the Genus database with same CATH homology
 2MV2 A;  3EG9 B;  2KVK A;  1F7S A;  1M2O A;  5KYU B;  1NMD G;  5L6W C;  5KYX A;  1RGI G;  1YAG G;  3EGD A;  4JD2 H;  5KYY B;  4KED A;  1CNU A;  3EFO A;  1PD1 A;  2XFA A;  2NUT A;  1M4J A;  1AHQ A;  3EGX A;  2W0I A;  2QTV A;  1EQY S;  5FAF A;  1HQZ 1;  2NUP B;  2LXX A;  3Q2B A;  4KEE A;  2FF6 G;  2VIL A;  5HVK B;  5KYW B;  1AK6 A;  1T3Y A;  3FG7 A;  1YVN G;  1NM1 G;  5IVU A;  1WFS A;  3A5L S;  3EG9 A;  3CJB G;  1UDM A;  5DD2 A;  1COF A;  1T44 G;  1KCQ A;  1Q8X A;  1DEJ S;  4BEX 1;  3EH2 A;  1WM4 A;  4PKG G;  3CI5 G;  1M2V B;  5KYN A;  3CJC G;  1C0G S;  1PD0 A;  2HD7 A;  5KYW A;  1WNJ A;  1VKK A;  5KYX B;  2LLF A;  3FFK A;  1AK7 A;  1D0N A;  2D8B A;  2L72 A;  3TU5 B;  1TMW A;  1MDU A;  5KYU A;  3EGX B;  1T2L A;  1V6F A;  1H1V G;  2MOT A;  5KYY A;  4PKI G;  1P8Z G;  5HVK D;  1ESV S;  1SVY A;  2MP4 A;  4CBW G;  4CBX G;  2FH3 A;  2VIK A;  2XF1 A;  3A5M S;  2LJ8 A;  3DA7 A;  1M2V A;  1P8X A;  1C0F S;  2NUP A;  2FF3 A;  3CIP G;  3A5O S;  1CFY A;  4KEF A;  3EGD B;  2FH1 A;  3L50 A;  4CBU G;  3A5N S;  3FG6 A;  3EFO B;  1NPH A;  1QPV A;  2FH4 A;  2NUT B;  2FH2 A;  1JHW A;  1SVR A;  5A1M A;  3DAW B;  4S10 C;  1VFQ A;  1NLV G;  2VAC A;  4LIZ A;  1SVQ A;  1J72 A;  2FGH A;  3EH1 A;  1X67 A;  1TVJ A;  2I2Q A;  5FAE A;  4PKH B;  1T3X A;  1Q8G A;  1PCX A;  4Z94 G;  3FFN A;  1D4X G; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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