2FH3A

C-terminal half of gelsolin soaked in low calcium at ph 8
Total Genus 92
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
92
sequence length
330
structure length
321
Chain Sequence
MDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAYRTSPRLKDKKMHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDTPITVVKQGFEPPSFVGWFLGWDDDYW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Calcium ion exchange in crystalline gelsolin
pubmed doi rcsb
molecule tags Contractile protein
source organism Homo sapiens
molecule keywords Gelsolin
total genus 92
structure length 321
sequence length 330
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2005-12-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00626 Gelsolin Gelsolin repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 2fh3A01
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 2fh3A03
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 2fh3A02
4CBWG 2NUTA 2HD7A 1J72A 3FFKA 3EGDA 1C0GS 1M2VA 1T44G 5HVKB 2D8BA 4JD2H 3EFOA 1D0NA 2FH3A 5KYUB 1SVRA 3A5NS 5KYWB 5A1MA 1CNUA 1NM1G 1CFYA 2NUPA 1UDMA 1PCXA 1X67A 3CIPG 1TVJA 3EG9A 1MDUA 1AHQA 1VKKA 3CI5G 1M2VB 4LIZA 2W0IA 2FF6G 1PD1A 4CBXG 3A5LS 4KEDA 1F7SA 2I2QA 2VIKA 4KEEA 1DEJS 2XF1A 2L72A 4PKHB 4KEFA 1KCQA 3FG7A 1NPHA 1JHWA 3DAWB 1HQZ1 4PKGG 2MP4A 1P8ZG 1T3YA 2MV2A 5DD2A 3CJBG 2NUTB 5KYYB 1P8XA 3CJCG 3EGXA 1RGIG 1YAGG 2KVKA 3A5MS 3EH1A 4S10C 5HVKD 5KYNA 1VFQA 3EH2A 3A5OS 2FF3A 2MOTA 3EGDB 3FFNA 1AK6A 1M4JA 1WFSA 1T3XA 5L6WC 1NMDG 1SVYA 1Q8XA 2FGHA 3EFOB 1NLVG 5FAFA 2FH4A 5FAEA 1D4XG 2FH2A 3TU5B 4PKIG 5KYWA 1V6FA 2NUPB 1Q8GA 3FG6A 1WNJA 3EG9B 5KYXA 2XFAA 4BEX1 4CBUG 1ESVS 1C0FS 1YVNG 1COFA 1TMWA 1PD0A 1QPVA 1EQYS 2FH1A 1SVQA 1M2OA 1WM4A 1H1VG 2LXXA 5KYUA 2QTVA 3Q2BA 5IVUA 3EGXB 2LJ8A 3L50A 4Z94G 5KYXB 1AK7A 2VACA 2LLFA 2VILA 1T2LA 5KYYA
chains in the Genus database with same CATH superfamily
4CBWG 2NUTA 2HD7A 1J72A 3FFKA 3EGDA 1C0GS 1M2VA 1T44G 5HVKB 2D8BA 4JD2H 3EFOA 1D0NA 2FH3A 5KYUB 1SVRA 3A5NS 5KYWB 5A1MA 1CNUA 1NM1G 1CFYA 2NUPA 1UDMA 1PCXA 1X67A 3CIPG 1TVJA 3EG9A 1MDUA 1AHQA 1VKKA 3CI5G 1M2VB 4LIZA 2W0IA 2FF6G 1PD1A 4CBXG 3A5LS 4KEDA 1F7SA 2I2QA 2VIKA 4KEEA 1DEJS 2XF1A 2L72A 4PKHB 4KEFA 1KCQA 3FG7A 1NPHA 1JHWA 3DAWB 3DA7A 1HQZ1 4PKGG 2MP4A 1P8ZG 1T3YA 2MV2A 5DD2A 3CJBG 2NUTB 5KYYB 1P8XA 3CJCG 3EGXA 1RGIG 1YAGG 2KVKA 3A5MS 3EH1A 4S10C 5HVKD 5KYNA 1VFQA 3EH2A 3A5OS 2FF3A 2MOTA 3EGDB 3FFNA 1AK6A 1M4JA 1WFSA 1T3XA 5L6WC 1NMDG 1SVYA 1Q8XA 2FGHA 3EFOB 1NLVG 5FAFA 2FH4A 5FAEA 1D4XG 2FH2A 3TU5B 4PKIG 5KYWA 1V6FA 2NUPB 1Q8GA 3FG6A 1WNJA 3EG9B 5KYXA 2XFAA 4BEX1 4CBUG 1ESVS 1C0FS 1YVNG 1COFA 1TMWA 1PD0A 1QPVA 1EQYS 2FH1A 1SVQA 1M2OA 1WM4A 1H1VG 2LXXA 5KYUA 2QTVA 3Q2BA 5IVUA 3EGXB 2LJ8A 3L50A 4Z94G 5KYXB 1AK7A 2VACA 2LLFA 2VILA 1T2LA 5KYYA
chains in the Genus database with same CATH topology
4CBWG 2NUTA 2HD7A 1J72A 3FFKA 3EGDA 1C0GS 1M2VA 1T44G 5HVKB 2D8BA 4JD2H 3EFOA 1D0NA 2FH3A 5KYUB 1SVRA 3A5NS 5KYWB 5A1MA 1CNUA 1NM1G 1CFYA 2NUPA 1UDMA 1PCXA 1X67A 3CIPG 1TVJA 3EG9A 1MDUA 1AHQA 1VKKA 3CI5G 1M2VB 4LIZA 2W0IA 2FF6G 1PD1A 4CBXG 3A5LS 4KEDA 1F7SA 2I2QA 2VIKA 4KEEA 1DEJS 2XF1A 2L72A 4PKHB 4KEFA 1KCQA 3FG7A 1NPHA 1JHWA 3DAWB 3DA7A 1HQZ1 4PKGG 2MP4A 1P8ZG 1T3YA 2MV2A 5DD2A 3CJBG 2NUTB 5KYYB 1P8XA 3CJCG 3EGXA 1RGIG 1YAGG 2KVKA 3A5MS 3EH1A 4S10C 5HVKD 5KYNA 1VFQA 3EH2A 3A5OS 2FF3A 2MOTA 3EGDB 3FFNA 1AK6A 1M4JA 1WFSA 1T3XA 5L6WC 1NMDG 1SVYA 1Q8XA 2FGHA 3EFOB 1NLVG 5FAFA 2FH4A 5FAEA 1D4XG 2FH2A 3TU5B 4PKIG 5KYWA 1V6FA 2NUPB 1Q8GA 3FG6A 1WNJA 3EG9B 5KYXA 2XFAA 4BEX1 4CBUG 1ESVS 1C0FS 1YVNG 1COFA 1TMWA 1PD0A 1QPVA 1EQYS 2FH1A 1SVQA 1M2OA 1WM4A 1H1VG 2LXXA 5KYUA 2QTVA 3Q2BA 5IVUA 3EGXB 2LJ8A 3L50A 4Z94G 5KYXB 1AK7A 2VACA 2LLFA 2VILA 1T2LA 5KYYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4CBW G;  2NUT A;  2HD7 A;  1J72 A;  3FFK A;  3EGD A;  1C0G S;  1M2V A;  1T44 G;  5HVK B;  2D8B A;  4JD2 H;  3EFO A;  1D0N A;  2FH3 A;  5KYU B;  1SVR A;  3A5N S;  5KYW B;  5A1M A;  1CNU A;  1NM1 G;  1CFY A;  2NUP A;  1UDM A;  1PCX A;  1X67 A;  3CIP G;  1TVJ A;  3EG9 A;  1MDU A;  1AHQ A;  1VKK A;  3CI5 G;  1M2V B;  4LIZ A;  2W0I A;  2FF6 G;  1PD1 A;  4CBX G;  3A5L S;  4KED A;  1F7S A;  2I2Q A;  2VIK A;  4KEE A;  1DEJ S;  2XF1 A;  2L72 A;  4PKH B;  4KEF A;  1KCQ A;  3FG7 A;  1NPH A;  1JHW A;  3DAW B;  1HQZ 1;  4PKG G;  2MP4 A;  1P8Z G;  1T3Y A;  2MV2 A;  5DD2 A;  3CJB G;  2NUT B;  5KYY B;  1P8X A;  3CJC G;  3EGX A;  1RGI G;  1YAG G;  2KVK A;  3A5M S;  3EH1 A;  4S10 C;  5HVK D;  5KYN A;  1VFQ A;  3EH2 A;  3A5O S;  2FF3 A;  2MOT A;  3EGD B;  3FFN A;  1AK6 A;  1M4J A;  1WFS A;  1T3X A;  5L6W C;  1NMD G;  1SVY A;  1Q8X A;  2FGH A;  3EFO B;  1NLV G;  5FAF A;  2FH4 A;  5FAE A;  1D4X G;  2FH2 A;  3TU5 B;  4PKI G;  5KYW A;  1V6F A;  2NUP B;  1Q8G A;  3FG6 A;  1WNJ A;  3EG9 B;  5KYX A;  2XFA A;  4BEX 1;  4CBU G;  1ESV S;  1C0F S;  1YVN G;  1COF A;  1TMW A;  1PD0 A;  1QPV A;  1EQY S;  2FH1 A;  1SVQ A;  1M2O A;  1WM4 A;  1H1V G;  2LXX A;  5KYU A;  2QTV A;  3Q2B A;  5IVU A;  3EGX B;  2LJ8 A;  3L50 A;  4Z94 G;  5KYX B;  1AK7 A;  2VAC A;  2LLF A;  2VIL A;  1T2L A;  5KYY A; 
#chains in the Genus database with same CATH topology
 4CBW G;  2NUT A;  2HD7 A;  1J72 A;  3FFK A;  3EGD A;  1C0G S;  1M2V A;  1T44 G;  5HVK B;  2D8B A;  4JD2 H;  3EFO A;  1D0N A;  2FH3 A;  5KYU B;  1SVR A;  3A5N S;  5KYW B;  5A1M A;  1CNU A;  1NM1 G;  1CFY A;  2NUP A;  1UDM A;  1PCX A;  1X67 A;  3CIP G;  1TVJ A;  3EG9 A;  1MDU A;  1AHQ A;  1VKK A;  3CI5 G;  1M2V B;  4LIZ A;  2W0I A;  2FF6 G;  1PD1 A;  4CBX G;  3A5L S;  4KED A;  1F7S A;  2I2Q A;  2VIK A;  4KEE A;  1DEJ S;  2XF1 A;  2L72 A;  4PKH B;  4KEF A;  1KCQ A;  3FG7 A;  1NPH A;  1JHW A;  3DAW B;  3DA7 A;  1HQZ 1;  4PKG G;  2MP4 A;  1P8Z G;  1T3Y A;  2MV2 A;  5DD2 A;  3CJB G;  2NUT B;  5KYY B;  1P8X A;  3CJC G;  3EGX A;  1RGI G;  1YAG G;  2KVK A;  3A5M S;  3EH1 A;  4S10 C;  5HVK D;  5KYN A;  1VFQ A;  3EH2 A;  3A5O S;  2FF3 A;  2MOT A;  3EGD B;  3FFN A;  1AK6 A;  1M4J A;  1WFS A;  1T3X A;  5L6W C;  1NMD G;  1SVY A;  1Q8X A;  2FGH A;  3EFO B;  1NLV G;  5FAF A;  2FH4 A;  5FAE A;  1D4X G;  2FH2 A;  3TU5 B;  4PKI G;  5KYW A;  1V6F A;  2NUP B;  1Q8G A;  3FG6 A;  1WNJ A;  3EG9 B;  5KYX A;  2XFA A;  4BEX 1;  4CBU G;  1ESV S;  1C0F S;  1YVN G;  1COF A;  1TMW A;  1PD0 A;  1QPV A;  1EQY S;  2FH1 A;  1SVQ A;  1M2O A;  1WM4 A;  1H1V G;  2LXX A;  5KYU A;  2QTV A;  3Q2B A;  5IVU A;  3EGX B;  2LJ8 A;  3L50 A;  4Z94 G;  5KYX B;  1AK7 A;  2VAC A;  2LLF A;  2VIL A;  1T2L A;  5KYY A; 
#chains in the Genus database with same CATH homology
 4CBW G;  2NUT A;  2HD7 A;  1J72 A;  3FFK A;  3EGD A;  1C0G S;  1M2V A;  1T44 G;  5HVK B;  2D8B A;  4JD2 H;  3EFO A;  1D0N A;  2FH3 A;  5KYU B;  1SVR A;  3A5N S;  5KYW B;  5A1M A;  1CNU A;  1NM1 G;  1CFY A;  2NUP A;  1UDM A;  1PCX A;  1X67 A;  3CIP G;  1TVJ A;  3EG9 A;  1MDU A;  1AHQ A;  1VKK A;  3CI5 G;  1M2V B;  4LIZ A;  2W0I A;  2FF6 G;  1PD1 A;  4CBX G;  3A5L S;  4KED A;  1F7S A;  2I2Q A;  2VIK A;  4KEE A;  1DEJ S;  2XF1 A;  2L72 A;  4PKH B;  4KEF A;  1KCQ A;  3FG7 A;  1NPH A;  1JHW A;  3DAW B;  3DA7 A;  1HQZ 1;  4PKG G;  2MP4 A;  1P8Z G;  1T3Y A;  2MV2 A;  5DD2 A;  3CJB G;  2NUT B;  5KYY B;  1P8X A;  3CJC G;  3EGX A;  1RGI G;  1YAG G;  2KVK A;  3A5M S;  3EH1 A;  4S10 C;  5HVK D;  5KYN A;  1VFQ A;  3EH2 A;  3A5O S;  2FF3 A;  2MOT A;  3EGD B;  3FFN A;  1AK6 A;  1M4J A;  1WFS A;  1T3X A;  5L6W C;  1NMD G;  1SVY A;  1Q8X A;  2FGH A;  3EFO B;  1NLV G;  5FAF A;  2FH4 A;  5FAE A;  1D4X G;  2FH2 A;  3TU5 B;  4PKI G;  5KYW A;  1V6F A;  2NUP B;  1Q8G A;  3FG6 A;  1WNJ A;  3EG9 B;  5KYX A;  2XFA A;  4BEX 1;  4CBU G;  1ESV S;  1C0F S;  1YVN G;  1COF A;  1TMW A;  1PD0 A;  1QPV A;  1EQY S;  2FH1 A;  1SVQ A;  1M2O A;  1WM4 A;  1H1V G;  2LXX A;  5KYU A;  2QTV A;  3Q2B A;  5IVU A;  3EGX B;  2LJ8 A;  3L50 A;  4Z94 G;  5KYX B;  1AK7 A;  2VAC A;  2LLF A;  2VIL A;  1T2L A;  5KYY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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