2L72A

Solution structure and dynamics of adf from toxoplasma gondii (tgadf)
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
118
structure length
118
Chain Sequence
MASGMGVDENCVARFNELKIRKTVKWIVFKIENTKIVVEKDGKGNADEFRGALPANDCRFGVYDCGNKIQFVLWCPDNAPVKPRMTYASSKDALLKKLDGATAVALEAHEMGDLAPLA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure and dynamics of ADF from Toxoplasma gondii
pubmed doi rcsb
molecule tags Protein binding
source organism Toxoplasma gondii
molecule keywords Actin depolymerizing factor, putative
total genus 23
structure length 118
sequence length 118
ec nomenclature
pdb deposition date 2010-12-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00241 Cofilin_ADF Cofilin/tropomyosin-type actin-binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 2l72A00
1JHWA 1D4XG 3L50A 2MOTA 2MV2A 2QTVA 2NUPB 4CBUG 1M2VB 1WM4A 1PD1A 1VKKA 3EGDA 5DD2A 2HD7A 2FH1A 4LIZA 5KYYA 4CBXG 2FH4A 1C0FS 3FG6A 2D8BA 3EGXA 3A5LS 1SVYA 2MP4A 2I2QA 1TMWA 3EH2A 1CNUA 1P8ZG 5HVKD 5KYWA 4S10C 2LJ8A 5KYUB 2NUTA 3EH1A 2VILA 1MDUA 1NMDG 1T44G 1X67A 3CJCG 1AK6A 3EG9B 2FGHA 1J72A 4KEEA 1QPVA 3EFOA 3FFNA 1EQYS 3CJBG 1HQZ1 5L6WC 5A1MA 2FF6G 4PKIG 3A5NS 1WNJA 2LXXA 2L72A 2FF3A 4JD2H 5HVKB 3EGDB 1CFYA 1AK7A 2W0IA 1T3XA 3TU5B 5KYYB 2XFAA 3EGXB 1YAGG 1NLVG 1M4JA 1V6FA 1P8XA 5KYWB 3FFKA 1M2OA 2FH3A 2NUTB 1PCXA 1PD0A 5KYXA 4KEDA 4PKGG 1SVRA 1Q8XA 2FH2A 1DEJS 1RGIG 2NUPA 1COFA 1SVQA 1M2VA 1ESVS 2VIKA 1F7SA 1KCQA 3EFOB 1TVJA 1T2LA 5FAFA 2VACA 1AHQA 1NM1G 4BEX1 4Z94G 1C0GS 3Q2BA 1YVNG 1Q8GA 3DAWB 1VFQA 2XF1A 5IVUA 4KEFA 4CBWG 3A5OS 5KYUA 5KYNA 1H1VG 5FAEA 3CI5G 2KVKA 2LLFA 1D0NA 4PKHB 3A5MS 3EG9A 1NPHA 3CIPG 3FG7A 1T3YA 5KYXB 1UDMA 1WFSA
chains in the Genus database with same CATH superfamily
1JHWA 1D4XG 3L50A 2MOTA 2MV2A 2QTVA 2NUPB 4CBUG 1M2VB 1WM4A 1PD1A 1VKKA 3EGDA 5DD2A 2HD7A 2FH1A 4LIZA 5KYYA 4CBXG 2FH4A 1C0FS 3FG6A 2D8BA 3EGXA 3A5LS 1SVYA 2MP4A 2I2QA 1TMWA 3EH2A 1CNUA 1P8ZG 5HVKD 5KYWA 4S10C 2LJ8A 5KYUB 2NUTA 3EH1A 2VILA 1MDUA 1NMDG 1T44G 1X67A 3CJCG 1AK6A 3EG9B 2FGHA 1J72A 4KEEA 1QPVA 3EFOA 3FFNA 1EQYS 3CJBG 1HQZ1 5L6WC 5A1MA 2FF6G 4PKIG 3A5NS 1WNJA 2LXXA 2L72A 2FF3A 4JD2H 5HVKB 3EGDB 1CFYA 1AK7A 2W0IA 1T3XA 3TU5B 5KYYB 2XFAA 3EGXB 1YAGG 1NLVG 1M4JA 1V6FA 1P8XA 5KYWB 3FFKA 1M2OA 2FH3A 2NUTB 1PCXA 1PD0A 5KYXA 4KEDA 4PKGG 1SVRA 1Q8XA 2FH2A 1DEJS 1RGIG 2NUPA 1COFA 1SVQA 1M2VA 1ESVS 2VIKA 1F7SA 1KCQA 3DA7A 3EFOB 1TVJA 1T2LA 5FAFA 2VACA 1AHQA 1NM1G 4BEX1 4Z94G 1C0GS 3Q2BA 1YVNG 1Q8GA 3DAWB 1VFQA 2XF1A 5IVUA 4KEFA 4CBWG 3A5OS 5KYUA 5KYNA 1H1VG 5FAEA 3CI5G 2KVKA 2LLFA 1D0NA 4PKHB 3A5MS 3EG9A 1NPHA 3CIPG 3FG7A 1T3YA 5KYXB 1UDMA 1WFSA
chains in the Genus database with same CATH topology
1JHWA 1D4XG 3L50A 2MOTA 2MV2A 2QTVA 2NUPB 4CBUG 1M2VB 1WM4A 1PD1A 1VKKA 3EGDA 5DD2A 2HD7A 2FH1A 4LIZA 5KYYA 4CBXG 2FH4A 1C0FS 3FG6A 2D8BA 3EGXA 3A5LS 1SVYA 2MP4A 2I2QA 1TMWA 3EH2A 1CNUA 1P8ZG 5HVKD 5KYWA 4S10C 2LJ8A 5KYUB 2NUTA 3EH1A 2VILA 1MDUA 1NMDG 1T44G 1X67A 3CJCG 1AK6A 3EG9B 2FGHA 1J72A 4KEEA 1QPVA 3EFOA 3FFNA 1EQYS 3CJBG 1HQZ1 5L6WC 5A1MA 2FF6G 4PKIG 3A5NS 1WNJA 2LXXA 2L72A 2FF3A 4JD2H 5HVKB 3EGDB 1CFYA 1AK7A 2W0IA 1T3XA 3TU5B 5KYYB 2XFAA 3EGXB 1YAGG 1NLVG 1M4JA 1V6FA 1P8XA 5KYWB 3FFKA 1M2OA 2FH3A 2NUTB 1PCXA 1PD0A 5KYXA 4KEDA 4PKGG 1SVRA 1Q8XA 2FH2A 1DEJS 1RGIG 2NUPA 1COFA 1SVQA 1M2VA 1ESVS 2VIKA 1F7SA 1KCQA 3DA7A 3EFOB 1TVJA 1T2LA 5FAFA 2VACA 1AHQA 1NM1G 4BEX1 4Z94G 1C0GS 3Q2BA 1YVNG 1Q8GA 3DAWB 1VFQA 2XF1A 5IVUA 4KEFA 4CBWG 3A5OS 5KYUA 5KYNA 1H1VG 5FAEA 3CI5G 2KVKA 2LLFA 1D0NA 4PKHB 3A5MS 3EG9A 1NPHA 3CIPG 3FG7A 1T3YA 5KYXB 1UDMA 1WFSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1JHW A;  1D4X G;  3L50 A;  2MOT A;  2MV2 A;  2QTV A;  2NUP B;  4CBU G;  1M2V B;  1WM4 A;  1PD1 A;  1VKK A;  3EGD A;  5DD2 A;  2HD7 A;  2FH1 A;  4LIZ A;  5KYY A;  4CBX G;  2FH4 A;  1C0F S;  3FG6 A;  2D8B A;  3EGX A;  3A5L S;  1SVY A;  2MP4 A;  2I2Q A;  1TMW A;  3EH2 A;  1CNU A;  1P8Z G;  5HVK D;  5KYW A;  4S10 C;  2LJ8 A;  5KYU B;  2NUT A;  3EH1 A;  2VIL A;  1MDU A;  1NMD G;  1T44 G;  1X67 A;  3CJC G;  1AK6 A;  3EG9 B;  2FGH A;  1J72 A;  4KEE A;  1QPV A;  3EFO A;  3FFN A;  1EQY S;  3CJB G;  1HQZ 1;  5L6W C;  5A1M A;  2FF6 G;  4PKI G;  3A5N S;  1WNJ A;  2LXX A;  2L72 A;  2FF3 A;  4JD2 H;  5HVK B;  3EGD B;  1CFY A;  1AK7 A;  2W0I A;  1T3X A;  3TU5 B;  5KYY B;  2XFA A;  3EGX B;  1YAG G;  1NLV G;  1M4J A;  1V6F A;  1P8X A;  5KYW B;  3FFK A;  1M2O A;  2FH3 A;  2NUT B;  1PCX A;  1PD0 A;  5KYX A;  4KED A;  4PKG G;  1SVR A;  1Q8X A;  2FH2 A;  1DEJ S;  1RGI G;  2NUP A;  1COF A;  1SVQ A;  1M2V A;  1ESV S;  2VIK A;  1F7S A;  1KCQ A;  3EFO B;  1TVJ A;  1T2L A;  5FAF A;  2VAC A;  1AHQ A;  1NM1 G;  4BEX 1;  4Z94 G;  1C0G S;  3Q2B A;  1YVN G;  1Q8G A;  3DAW B;  1VFQ A;  2XF1 A;  5IVU A;  4KEF A;  4CBW G;  3A5O S;  5KYU A;  5KYN A;  1H1V G;  5FAE A;  3CI5 G;  2KVK A;  2LLF A;  1D0N A;  4PKH B;  3A5M S;  3EG9 A;  1NPH A;  3CIP G;  3FG7 A;  1T3Y A;  5KYX B;  1UDM A;  1WFS A; 
#chains in the Genus database with same CATH topology
 1JHW A;  1D4X G;  3L50 A;  2MOT A;  2MV2 A;  2QTV A;  2NUP B;  4CBU G;  1M2V B;  1WM4 A;  1PD1 A;  1VKK A;  3EGD A;  5DD2 A;  2HD7 A;  2FH1 A;  4LIZ A;  5KYY A;  4CBX G;  2FH4 A;  1C0F S;  3FG6 A;  2D8B A;  3EGX A;  3A5L S;  1SVY A;  2MP4 A;  2I2Q A;  1TMW A;  3EH2 A;  1CNU A;  1P8Z G;  5HVK D;  5KYW A;  4S10 C;  2LJ8 A;  5KYU B;  2NUT A;  3EH1 A;  2VIL A;  1MDU A;  1NMD G;  1T44 G;  1X67 A;  3CJC G;  1AK6 A;  3EG9 B;  2FGH A;  1J72 A;  4KEE A;  1QPV A;  3EFO A;  3FFN A;  1EQY S;  3CJB G;  1HQZ 1;  5L6W C;  5A1M A;  2FF6 G;  4PKI G;  3A5N S;  1WNJ A;  2LXX A;  2L72 A;  2FF3 A;  4JD2 H;  5HVK B;  3EGD B;  1CFY A;  1AK7 A;  2W0I A;  1T3X A;  3TU5 B;  5KYY B;  2XFA A;  3EGX B;  1YAG G;  1NLV G;  1M4J A;  1V6F A;  1P8X A;  5KYW B;  3FFK A;  1M2O A;  2FH3 A;  2NUT B;  1PCX A;  1PD0 A;  5KYX A;  4KED A;  4PKG G;  1SVR A;  1Q8X A;  2FH2 A;  1DEJ S;  1RGI G;  2NUP A;  1COF A;  1SVQ A;  1M2V A;  1ESV S;  2VIK A;  1F7S A;  1KCQ A;  3DA7 A;  3EFO B;  1TVJ A;  1T2L A;  5FAF A;  2VAC A;  1AHQ A;  1NM1 G;  4BEX 1;  4Z94 G;  1C0G S;  3Q2B A;  1YVN G;  1Q8G A;  3DAW B;  1VFQ A;  2XF1 A;  5IVU A;  4KEF A;  4CBW G;  3A5O S;  5KYU A;  5KYN A;  1H1V G;  5FAE A;  3CI5 G;  2KVK A;  2LLF A;  1D0N A;  4PKH B;  3A5M S;  3EG9 A;  1NPH A;  3CIP G;  3FG7 A;  1T3Y A;  5KYX B;  1UDM A;  1WFS A; 
#chains in the Genus database with same CATH homology
 1JHW A;  1D4X G;  3L50 A;  2MOT A;  2MV2 A;  2QTV A;  2NUP B;  4CBU G;  1M2V B;  1WM4 A;  1PD1 A;  1VKK A;  3EGD A;  5DD2 A;  2HD7 A;  2FH1 A;  4LIZ A;  5KYY A;  4CBX G;  2FH4 A;  1C0F S;  3FG6 A;  2D8B A;  3EGX A;  3A5L S;  1SVY A;  2MP4 A;  2I2Q A;  1TMW A;  3EH2 A;  1CNU A;  1P8Z G;  5HVK D;  5KYW A;  4S10 C;  2LJ8 A;  5KYU B;  2NUT A;  3EH1 A;  2VIL A;  1MDU A;  1NMD G;  1T44 G;  1X67 A;  3CJC G;  1AK6 A;  3EG9 B;  2FGH A;  1J72 A;  4KEE A;  1QPV A;  3EFO A;  3FFN A;  1EQY S;  3CJB G;  1HQZ 1;  5L6W C;  5A1M A;  2FF6 G;  4PKI G;  3A5N S;  1WNJ A;  2LXX A;  2L72 A;  2FF3 A;  4JD2 H;  5HVK B;  3EGD B;  1CFY A;  1AK7 A;  2W0I A;  1T3X A;  3TU5 B;  5KYY B;  2XFA A;  3EGX B;  1YAG G;  1NLV G;  1M4J A;  1V6F A;  1P8X A;  5KYW B;  3FFK A;  1M2O A;  2FH3 A;  2NUT B;  1PCX A;  1PD0 A;  5KYX A;  4KED A;  4PKG G;  1SVR A;  1Q8X A;  2FH2 A;  1DEJ S;  1RGI G;  2NUP A;  1COF A;  1SVQ A;  1M2V A;  1ESV S;  2VIK A;  1F7S A;  1KCQ A;  3DA7 A;  3EFO B;  1TVJ A;  1T2L A;  5FAF A;  2VAC A;  1AHQ A;  1NM1 G;  4BEX 1;  4Z94 G;  1C0G S;  3Q2B A;  1YVN G;  1Q8G A;  3DAW B;  1VFQ A;  2XF1 A;  5IVU A;  4KEF A;  4CBW G;  3A5O S;  5KYU A;  5KYN A;  1H1V G;  5FAE A;  3CI5 G;  2KVK A;  2LLF A;  1D0N A;  4PKH B;  3A5M S;  3EG9 A;  1NPH A;  3CIP G;  3FG7 A;  1T3Y A;  5KYX B;  1UDM A;  1WFS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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