2LJ8 | Genus

Total Genus 25

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	25
sequence length	136
structure length	136
Chain Sequence	MAMSGVSVADECVTALNDLRHKKSRYVIMHIVDQKSIAVKTIGERGANFDQFIEAIDKNVPCYAAFDFEYTTNDGPRDKLILISWNPDSGAPRTKMLYSSSRDALVPLTQGFQGIQANDASGLDFEEISRKVKSNR

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	1H and 15N Assigned Chemical Shifts for ADF/Cofilin from Trypanosoma brucei rcsb
molecule keywords	Cofilin/actin depolymerizing factor, putative
molecule tags	Protein binding
source organism	Trypanosoma brucei
total genus	25
structure length	136
sequence length	136
ec nomenclature
pdb deposition date	2011-09-08

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00241	Cofilin_ADF	Cofilin/tropomyosin-type actin-binding protein

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.40.20.10	Alpha Beta	3-Layer(aba) Sandwich	Severin	Severin	2lj8A00

2VILA 3CJCG 1AK6A 2L72A 2FF6G 1WNJA 3TU5B 2VIKA 3FFKA 2FGHA 2FH2A 1TMWA 1SVRA 4PKIG 3A5MS 2W0IA 3FG7A 5KYUA 1AK7A 2MV2A 3DAWB 2FF3A 1UDMA 1CNUA 4KEDA 1NLVG 2FH4A 1P8XA 1M4JA 1YAGG 2LLFA 2KVKA 1WFSA 3EFOB 4BEX1 3A5OS 2LJ8A 1T2LA 2MOTA 5KYNA 1VKKA 3EG9B 3CIPG 5KYUB 1NMDG 2HD7A 3EFOA 2XFAA 2NUPB 1P8ZG 1ESVS 1TVJA 1M2OA 5FAFA 3EG9A 1D4XG 4Z94G 1C0FS 1CFYA 1X67A 2NUPA 2NUTB 3EH1A 1T3XA 2D8BA 2I2QA 3EGDA 5A1MA 1J72A 5KYWB 2NUTA 4CBXG 3Q2BA 1H1VG 3EGXB 5IVUA 4CBWG 5KYWA 1DEJS 4LIZA 1Q8XA 1EQYS 1QPVA 1SVQA 3EGXA 3A5NS 1PD0A 3EGDB 3L50A 1COFA 1JHWA 5KYXB 1KCQA 5DD2A 1NM1G 2FH3A 5L6WC 4JD2H 4S10C 1D0NA 1Q8GA 5KYYA 2QTVA 1T44G 5KYXA 1M2VB 5FAEA 2XF1A 4CBUG 5HVKB 1PD1A 1T3YA 3FG6A 1MDUA 4KEEA 2FH1A 1HQZ1 1M2VA 2LXXA 1PCXA 1WM4A 4PKHB 3A5LS 1RGIG 2MP4A 1YVNG 3FFNA 3CI5G 3CJBG 1NPHA 5HVKD 2VACA 1C0GS 3EH2A 5KYYB 1F7SA 1SVYA 1VFQA 1AHQA 4PKGG 4KEFA 1V6FA
chains in the Genus database with same CATH superfamily

2VILA 3CJCG 3DA7A 1AK6A 2L72A 2FF6G 1WNJA 3TU5B 2VIKA 3FFKA 2FGHA 2FH2A 1TMWA 1SVRA 4PKIG 3A5MS 2W0IA 3FG7A 5KYUA 1AK7A 2MV2A 3DAWB 2FF3A 1UDMA 1CNUA 4KEDA 1NLVG 2FH4A 1P8XA 1M4JA 1YAGG 2LLFA 2KVKA 1WFSA 3EFOB 4BEX1 3A5OS 2LJ8A 1T2LA 2MOTA 5KYNA 1VKKA 3EG9B 3CIPG 5KYUB 1NMDG 2HD7A 3EFOA 2XFAA 2NUPB 1P8ZG 1ESVS 1TVJA 1M2OA 5FAFA 3EG9A 1D4XG 4Z94G 1C0FS 1CFYA 1X67A 2NUPA 2NUTB 3EH1A 1T3XA 2D8BA 2I2QA 3EGDA 5A1MA 1J72A 5KYWB 2NUTA 4CBXG 3Q2BA 1H1VG 3EGXB 5IVUA 4CBWG 5KYWA 1DEJS 4LIZA 1Q8XA 1EQYS 1QPVA 1SVQA 3EGXA 3A5NS 1PD0A 3EGDB 3L50A 1COFA 1JHWA 5KYXB 1KCQA 5DD2A 1NM1G 2FH3A 5L6WC 4JD2H 4S10C 1D0NA 1Q8GA 5KYYA 2QTVA 1T44G 5KYXA 1M2VB 5FAEA 2XF1A 4CBUG 5HVKB 1PD1A 1T3YA 3FG6A 1MDUA 4KEEA 2FH1A 1HQZ1 1M2VA 2LXXA 1PCXA 1WM4A 4PKHB 3A5LS 1RGIG 2MP4A 1YVNG 3FFNA 3CI5G 3CJBG 1NPHA 5HVKD 2VACA 1C0GS 3EH2A 5KYYB 1F7SA 1SVYA 1VFQA 1AHQA 4PKGG 4KEFA 1V6FA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 2VIL A;  3CJC G;  1AK6 A;  2L72 A;  2FF6 G;  1WNJ A;  3TU5 B;  2VIK A;  3FFK A;  2FGH A;  2FH2 A;  1TMW A;  1SVR A;  4PKI G;  3A5M S;  2W0I A;  3FG7 A;  5KYU A;  1AK7 A;  2MV2 A;  3DAW B;  2FF3 A;  1UDM A;  1CNU A;  4KED A;  1NLV G;  2FH4 A;  1P8X A;  1M4J A;  1YAG G;  2LLF A;  2KVK A;  1WFS A;  3EFO B;  4BEX 1;  3A5O S;  2LJ8 A;  1T2L A;  2MOT A;  5KYN A;  1VKK A;  3EG9 B;  3CIP G;  5KYU B;  1NMD G;  2HD7 A;  3EFO A;  2XFA A;  2NUP B;  1P8Z G;  1ESV S;  1TVJ A;  1M2O A;  5FAF A;  3EG9 A;  1D4X G;  4Z94 G;  1C0F S;  1CFY A;  1X67 A;  2NUP A;  2NUT B;  3EH1 A;  1T3X A;  2D8B A;  2I2Q A;  3EGD A;  5A1M A;  1J72 A;  5KYW B;  2NUT A;  4CBX G;  3Q2B A;  1H1V G;  3EGX B;  5IVU A;  4CBW G;  5KYW A;  1DEJ S;  4LIZ A;  1Q8X A;  1EQY S;  1QPV A;  1SVQ A;  3EGX A;  3A5N S;  1PD0 A;  3EGD B;  3L50 A;  1COF A;  1JHW A;  5KYX B;  1KCQ A;  5DD2 A;  1NM1 G;  2FH3 A;  5L6W C;  4JD2 H;  4S10 C;  1D0N A;  1Q8G A;  5KYY A;  2QTV A;  1T44 G;  5KYX A;  1M2V B;  5FAE A;  2XF1 A;  4CBU G;  5HVK B;  1PD1 A;  1T3Y A;  3FG6 A;  1MDU A;  4KEE A;  2FH1 A;  1HQZ 1;  1M2V A;  2LXX A;  1PCX A;  1WM4 A;  4PKH B;  3A5L S;  1RGI G;  2MP4 A;  1YVN G;  3FFN A;  3CI5 G;  3CJB G;  1NPH A;  5HVK D;  2VAC A;  1C0G S;  3EH2 A;  5KYY B;  1F7S A;  1SVY A;  1VFQ A;  1AHQ A;  4PKG G;  4KEF A;  1V6F A; 
#chains in the Genus database with same CATH topology
 2VIL A;  3CJC G;  3DA7 A;  1AK6 A;  2L72 A;  2FF6 G;  1WNJ A;  3TU5 B;  2VIK A;  3FFK A;  2FGH A;  2FH2 A;  1TMW A;  1SVR A;  4PKI G;  3A5M S;  2W0I A;  3FG7 A;  5KYU A;  1AK7 A;  2MV2 A;  3DAW B;  2FF3 A;  1UDM A;  1CNU A;  4KED A;  1NLV G;  2FH4 A;  1P8X A;  1M4J A;  1YAG G;  2LLF A;  2KVK A;  1WFS A;  3EFO B;  4BEX 1;  3A5O S;  2LJ8 A;  1T2L A;  2MOT A;  5KYN A;  1VKK A;  3EG9 B;  3CIP G;  5KYU B;  1NMD G;  2HD7 A;  3EFO A;  2XFA A;  2NUP B;  1P8Z G;  1ESV S;  1TVJ A;  1M2O A;  5FAF A;  3EG9 A;  1D4X G;  4Z94 G;  1C0F S;  1CFY A;  1X67 A;  2NUP A;  2NUT B;  3EH1 A;  1T3X A;  2D8B A;  2I2Q A;  3EGD A;  5A1M A;  1J72 A;  5KYW B;  2NUT A;  4CBX G;  3Q2B A;  1H1V G;  3EGX B;  5IVU A;  4CBW G;  5KYW A;  1DEJ S;  4LIZ A;  1Q8X A;  1EQY S;  1QPV A;  1SVQ A;  3EGX A;  3A5N S;  1PD0 A;  3EGD B;  3L50 A;  1COF A;  1JHW A;  5KYX B;  1KCQ A;  5DD2 A;  1NM1 G;  2FH3 A;  5L6W C;  4JD2 H;  4S10 C;  1D0N A;  1Q8G A;  5KYY A;  2QTV A;  1T44 G;  5KYX A;  1M2V B;  5FAE A;  2XF1 A;  4CBU G;  5HVK B;  1PD1 A;  1T3Y A;  3FG6 A;  1MDU A;  4KEE A;  2FH1 A;  1HQZ 1;  1M2V A;  2LXX A;  1PCX A;  1WM4 A;  4PKH B;  3A5L S;  1RGI G;  2MP4 A;  1YVN G;  3FFN A;  3CI5 G;  3CJB G;  1NPH A;  5HVK D;  2VAC A;  1C0G S;  3EH2 A;  5KYY B;  1F7S A;  1SVY A;  1VFQ A;  1AHQ A;  4PKG G;  4KEF A;  1V6F A; 
#chains in the Genus database with same CATH homology
 2VIL A;  3CJC G;  3DA7 A;  1AK6 A;  2L72 A;  2FF6 G;  1WNJ A;  3TU5 B;  2VIK A;  3FFK A;  2FGH A;  2FH2 A;  1TMW A;  1SVR A;  4PKI G;  3A5M S;  2W0I A;  3FG7 A;  5KYU A;  1AK7 A;  2MV2 A;  3DAW B;  2FF3 A;  1UDM A;  1CNU A;  4KED A;  1NLV G;  2FH4 A;  1P8X A;  1M4J A;  1YAG G;  2LLF A;  2KVK A;  1WFS A;  3EFO B;  4BEX 1;  3A5O S;  2LJ8 A;  1T2L A;  2MOT A;  5KYN A;  1VKK A;  3EG9 B;  3CIP G;  5KYU B;  1NMD G;  2HD7 A;  3EFO A;  2XFA A;  2NUP B;  1P8Z G;  1ESV S;  1TVJ A;  1M2O A;  5FAF A;  3EG9 A;  1D4X G;  4Z94 G;  1C0F S;  1CFY A;  1X67 A;  2NUP A;  2NUT B;  3EH1 A;  1T3X A;  2D8B A;  2I2Q A;  3EGD A;  5A1M A;  1J72 A;  5KYW B;  2NUT A;  4CBX G;  3Q2B A;  1H1V G;  3EGX B;  5IVU A;  4CBW G;  5KYW A;  1DEJ S;  4LIZ A;  1Q8X A;  1EQY S;  1QPV A;  1SVQ A;  3EGX A;  3A5N S;  1PD0 A;  3EGD B;  3L50 A;  1COF A;  1JHW A;  5KYX B;  1KCQ A;  5DD2 A;  1NM1 G;  2FH3 A;  5L6W C;  4JD2 H;  4S10 C;  1D0N A;  1Q8G A;  5KYY A;  2QTV A;  1T44 G;  5KYX A;  1M2V B;  5FAE A;  2XF1 A;  4CBU G;  5HVK B;  1PD1 A;  1T3Y A;  3FG6 A;  1MDU A;  4KEE A;  2FH1 A;  1HQZ 1;  1M2V A;  2LXX A;  1PCX A;  1WM4 A;  4PKH B;  3A5L S;  1RGI G;  2MP4 A;  1YVN G;  3FFN A;  3CI5 G;  3CJB G;  1NPH A;  5HVK D;  2VAC A;  1C0G S;  3EH2 A;  5KYY B;  1F7S A;  1SVY A;  1VFQ A;  1AHQ A;  4PKG G;  4KEF A;  1V6F A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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2LJ8A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations