2LJ8A

Solution structure of adf/cofilin from trypanosoma brucei
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
136
structure length
136
Chain Sequence
MAMSGVSVADECVTALNDLRHKKSRYVIMHIVDQKSIAVKTIGERGANFDQFIEAIDKNVPCYAAFDFEYTTNDGPRDKLILISWNPDSGAPRTKMLYSSSRDALVPLTQGFQGIQANDASGLDFEEISRKVKSNR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title 1H and 15N Assigned Chemical Shifts for ADF/Cofilin from Trypanosoma brucei
rcsb
molecule tags Protein binding
source organism Trypanosoma brucei
molecule keywords Cofilin/actin depolymerizing factor, putative
total genus 25
structure length 136
sequence length 136
ec nomenclature
pdb deposition date 2011-09-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00241 Cofilin_ADF Cofilin/tropomyosin-type actin-binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 2lj8A00
3CJCG 3FFKA 1T44G 1TVJA 3EG9A 2NUPB 1C0GS 5A1MA 3EGXA 2FH2A 1P8XA 3EG9B 2FF6G 2XF1A 1SVRA 5KYYA 4KEDA 5HVKD 1D4XG 1JHWA 3EGXB 3Q2BA 5KYYB 2FH4A 1DEJS 4CBUG 1SVQA 4Z94G 4PKGG 1NLVG 5KYNA 1M4JA 1M2VA 2NUTA 5KYUA 2MP4A 1M2VB 2NUTB 2FF3A 2HD7A 5KYUB 1UDMA 2LLFA 5FAFA 2MOTA 1M2OA 1PD0A 1ESVS 4KEFA 1AHQA 1T3XA 2LXXA 4PKIG 1VFQA 5FAEA 1V6FA 1T3YA 4PKHB 5HVKB 3DAWB 2I2QA 3EH1A 2D8BA 1YVNG 1D0NA 1X67A 1YAGG 1TMWA 1WFSA 4CBWG 3FG7A 1J72A 5IVUA 1NM1G 3L50A 1VKKA 4BEX1 3A5NS 1WM4A 2VIKA 3A5MS 3TU5B 1WNJA 3EGDA 5KYWA 1C0FS 1AK6A 4S10C 1EQYS 2MV2A 3FFNA 3EGDB 2XFAA 5KYWB 3EH2A 1T2LA 1CFYA 1COFA 2LJ8A 3CI5G 1PCXA 1H1VG 3A5OS 2FH1A 3EFOA 5KYXA 1CNUA 5L6WC 1RGIG 4JD2H 4LIZA 1MDUA 3FG6A 3EFOB 3A5LS 5KYXB 1KCQA 3CJBG 1Q8XA 4CBXG 3CIPG 2L72A 1QPVA 2FGHA 1F7SA 1Q8GA 1PD1A 1HQZ1 2KVKA 1P8ZG 1NMDG 1NPHA 5DD2A 2VACA 2QTVA 2FH3A 1SVYA 2VILA 4KEEA 2W0IA 2NUPA 1AK7A
chains in the Genus database with same CATH superfamily
3CJCG 3FFKA 1T44G 1TVJA 3EG9A 2NUPB 1C0GS 5A1MA 3EGXA 2FH2A 1P8XA 3EG9B 2FF6G 2XF1A 1SVRA 5KYYA 4KEDA 5HVKD 1D4XG 1JHWA 3EGXB 3Q2BA 3DA7A 5KYYB 2FH4A 1DEJS 4CBUG 1SVQA 4Z94G 4PKGG 1NLVG 5KYNA 1M4JA 1M2VA 2NUTA 5KYUA 2MP4A 1M2VB 2NUTB 2FF3A 2HD7A 5KYUB 1UDMA 2LLFA 5FAFA 2MOTA 1M2OA 1PD0A 1ESVS 4KEFA 1AHQA 1T3XA 2LXXA 4PKIG 1VFQA 5FAEA 1V6FA 1T3YA 4PKHB 5HVKB 3DAWB 2I2QA 3EH1A 2D8BA 1YVNG 1D0NA 1X67A 1YAGG 1TMWA 1WFSA 4CBWG 3FG7A 1J72A 5IVUA 1NM1G 3L50A 1VKKA 4BEX1 3A5NS 1WM4A 2VIKA 3A5MS 3TU5B 1WNJA 3EGDA 5KYWA 1C0FS 1AK6A 4S10C 1EQYS 2MV2A 3FFNA 3EGDB 2XFAA 5KYWB 3EH2A 1T2LA 1CFYA 1COFA 2LJ8A 3CI5G 1PCXA 1H1VG 3A5OS 2FH1A 3EFOA 5KYXA 1CNUA 5L6WC 1RGIG 4JD2H 4LIZA 1MDUA 3FG6A 3EFOB 3A5LS 5KYXB 1KCQA 3CJBG 1Q8XA 4CBXG 3CIPG 2L72A 1QPVA 2FGHA 1F7SA 1Q8GA 1PD1A 1HQZ1 2KVKA 1P8ZG 1NMDG 1NPHA 5DD2A 2VACA 2QTVA 2FH3A 1SVYA 2VILA 4KEEA 2W0IA 2NUPA 1AK7A
chains in the Genus database with same CATH topology
3CJCG 3FFKA 1T44G 1TVJA 3EG9A 2NUPB 1C0GS 5A1MA 3EGXA 2FH2A 1P8XA 3EG9B 2FF6G 2XF1A 1SVRA 5KYYA 4KEDA 5HVKD 1D4XG 1JHWA 3EGXB 3Q2BA 3DA7A 5KYYB 2FH4A 1DEJS 4CBUG 1SVQA 4Z94G 4PKGG 1NLVG 5KYNA 1M4JA 1M2VA 2NUTA 5KYUA 2MP4A 1M2VB 2NUTB 2FF3A 2HD7A 5KYUB 1UDMA 2LLFA 5FAFA 2MOTA 1M2OA 1PD0A 1ESVS 4KEFA 1AHQA 1T3XA 2LXXA 4PKIG 1VFQA 5FAEA 1V6FA 1T3YA 4PKHB 5HVKB 3DAWB 2I2QA 3EH1A 2D8BA 1YVNG 1D0NA 1X67A 1YAGG 1TMWA 1WFSA 4CBWG 3FG7A 1J72A 5IVUA 1NM1G 3L50A 1VKKA 4BEX1 3A5NS 1WM4A 2VIKA 3A5MS 3TU5B 1WNJA 3EGDA 5KYWA 1C0FS 1AK6A 4S10C 1EQYS 2MV2A 3FFNA 3EGDB 2XFAA 5KYWB 3EH2A 1T2LA 1CFYA 1COFA 2LJ8A 3CI5G 1PCXA 1H1VG 3A5OS 2FH1A 3EFOA 5KYXA 1CNUA 5L6WC 1RGIG 4JD2H 4LIZA 1MDUA 3FG6A 3EFOB 3A5LS 5KYXB 1KCQA 3CJBG 1Q8XA 4CBXG 3CIPG 2L72A 1QPVA 2FGHA 1F7SA 1Q8GA 1PD1A 1HQZ1 2KVKA 1P8ZG 1NMDG 1NPHA 5DD2A 2VACA 2QTVA 2FH3A 1SVYA 2VILA 4KEEA 2W0IA 2NUPA 1AK7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CJC G;  3FFK A;  1T44 G;  1TVJ A;  3EG9 A;  2NUP B;  1C0G S;  5A1M A;  3EGX A;  2FH2 A;  1P8X A;  3EG9 B;  2FF6 G;  2XF1 A;  1SVR A;  5KYY A;  4KED A;  5HVK D;  1D4X G;  1JHW A;  3EGX B;  3Q2B A;  5KYY B;  2FH4 A;  1DEJ S;  4CBU G;  1SVQ A;  4Z94 G;  4PKG G;  1NLV G;  5KYN A;  1M4J A;  1M2V A;  2NUT A;  5KYU A;  2MP4 A;  1M2V B;  2NUT B;  2FF3 A;  2HD7 A;  5KYU B;  1UDM A;  2LLF A;  5FAF A;  2MOT A;  1M2O A;  1PD0 A;  1ESV S;  4KEF A;  1AHQ A;  1T3X A;  2LXX A;  4PKI G;  1VFQ A;  5FAE A;  1V6F A;  1T3Y A;  4PKH B;  5HVK B;  3DAW B;  2I2Q A;  3EH1 A;  2D8B A;  1YVN G;  1D0N A;  1X67 A;  1YAG G;  1TMW A;  1WFS A;  4CBW G;  3FG7 A;  1J72 A;  5IVU A;  1NM1 G;  3L50 A;  1VKK A;  4BEX 1;  3A5N S;  1WM4 A;  2VIK A;  3A5M S;  3TU5 B;  1WNJ A;  3EGD A;  5KYW A;  1C0F S;  1AK6 A;  4S10 C;  1EQY S;  2MV2 A;  3FFN A;  3EGD B;  2XFA A;  5KYW B;  3EH2 A;  1T2L A;  1CFY A;  1COF A;  2LJ8 A;  3CI5 G;  1PCX A;  1H1V G;  3A5O S;  2FH1 A;  3EFO A;  5KYX A;  1CNU A;  5L6W C;  1RGI G;  4JD2 H;  4LIZ A;  1MDU A;  3FG6 A;  3EFO B;  3A5L S;  5KYX B;  1KCQ A;  3CJB G;  1Q8X A;  4CBX G;  3CIP G;  2L72 A;  1QPV A;  2FGH A;  1F7S A;  1Q8G A;  1PD1 A;  1HQZ 1;  2KVK A;  1P8Z G;  1NMD G;  1NPH A;  5DD2 A;  2VAC A;  2QTV A;  2FH3 A;  1SVY A;  2VIL A;  4KEE A;  2W0I A;  2NUP A;  1AK7 A; 
#chains in the Genus database with same CATH topology
 3CJC G;  3FFK A;  1T44 G;  1TVJ A;  3EG9 A;  2NUP B;  1C0G S;  5A1M A;  3EGX A;  2FH2 A;  1P8X A;  3EG9 B;  2FF6 G;  2XF1 A;  1SVR A;  5KYY A;  4KED A;  5HVK D;  1D4X G;  1JHW A;  3EGX B;  3Q2B A;  3DA7 A;  5KYY B;  2FH4 A;  1DEJ S;  4CBU G;  1SVQ A;  4Z94 G;  4PKG G;  1NLV G;  5KYN A;  1M4J A;  1M2V A;  2NUT A;  5KYU A;  2MP4 A;  1M2V B;  2NUT B;  2FF3 A;  2HD7 A;  5KYU B;  1UDM A;  2LLF A;  5FAF A;  2MOT A;  1M2O A;  1PD0 A;  1ESV S;  4KEF A;  1AHQ A;  1T3X A;  2LXX A;  4PKI G;  1VFQ A;  5FAE A;  1V6F A;  1T3Y A;  4PKH B;  5HVK B;  3DAW B;  2I2Q A;  3EH1 A;  2D8B A;  1YVN G;  1D0N A;  1X67 A;  1YAG G;  1TMW A;  1WFS A;  4CBW G;  3FG7 A;  1J72 A;  5IVU A;  1NM1 G;  3L50 A;  1VKK A;  4BEX 1;  3A5N S;  1WM4 A;  2VIK A;  3A5M S;  3TU5 B;  1WNJ A;  3EGD A;  5KYW A;  1C0F S;  1AK6 A;  4S10 C;  1EQY S;  2MV2 A;  3FFN A;  3EGD B;  2XFA A;  5KYW B;  3EH2 A;  1T2L A;  1CFY A;  1COF A;  2LJ8 A;  3CI5 G;  1PCX A;  1H1V G;  3A5O S;  2FH1 A;  3EFO A;  5KYX A;  1CNU A;  5L6W C;  1RGI G;  4JD2 H;  4LIZ A;  1MDU A;  3FG6 A;  3EFO B;  3A5L S;  5KYX B;  1KCQ A;  3CJB G;  1Q8X A;  4CBX G;  3CIP G;  2L72 A;  1QPV A;  2FGH A;  1F7S A;  1Q8G A;  1PD1 A;  1HQZ 1;  2KVK A;  1P8Z G;  1NMD G;  1NPH A;  5DD2 A;  2VAC A;  2QTV A;  2FH3 A;  1SVY A;  2VIL A;  4KEE A;  2W0I A;  2NUP A;  1AK7 A; 
#chains in the Genus database with same CATH homology
 3CJC G;  3FFK A;  1T44 G;  1TVJ A;  3EG9 A;  2NUP B;  1C0G S;  5A1M A;  3EGX A;  2FH2 A;  1P8X A;  3EG9 B;  2FF6 G;  2XF1 A;  1SVR A;  5KYY A;  4KED A;  5HVK D;  1D4X G;  1JHW A;  3EGX B;  3Q2B A;  3DA7 A;  5KYY B;  2FH4 A;  1DEJ S;  4CBU G;  1SVQ A;  4Z94 G;  4PKG G;  1NLV G;  5KYN A;  1M4J A;  1M2V A;  2NUT A;  5KYU A;  2MP4 A;  1M2V B;  2NUT B;  2FF3 A;  2HD7 A;  5KYU B;  1UDM A;  2LLF A;  5FAF A;  2MOT A;  1M2O A;  1PD0 A;  1ESV S;  4KEF A;  1AHQ A;  1T3X A;  2LXX A;  4PKI G;  1VFQ A;  5FAE A;  1V6F A;  1T3Y A;  4PKH B;  5HVK B;  3DAW B;  2I2Q A;  3EH1 A;  2D8B A;  1YVN G;  1D0N A;  1X67 A;  1YAG G;  1TMW A;  1WFS A;  4CBW G;  3FG7 A;  1J72 A;  5IVU A;  1NM1 G;  3L50 A;  1VKK A;  4BEX 1;  3A5N S;  1WM4 A;  2VIK A;  3A5M S;  3TU5 B;  1WNJ A;  3EGD A;  5KYW A;  1C0F S;  1AK6 A;  4S10 C;  1EQY S;  2MV2 A;  3FFN A;  3EGD B;  2XFA A;  5KYW B;  3EH2 A;  1T2L A;  1CFY A;  1COF A;  2LJ8 A;  3CI5 G;  1PCX A;  1H1V G;  3A5O S;  2FH1 A;  3EFO A;  5KYX A;  1CNU A;  5L6W C;  1RGI G;  4JD2 H;  4LIZ A;  1MDU A;  3FG6 A;  3EFO B;  3A5L S;  5KYX B;  1KCQ A;  3CJB G;  1Q8X A;  4CBX G;  3CIP G;  2L72 A;  1QPV A;  2FGH A;  1F7S A;  1Q8G A;  1PD1 A;  1HQZ 1;  2KVK A;  1P8Z G;  1NMD G;  1NPH A;  5DD2 A;  2VAC A;  2QTV A;  2FH3 A;  1SVY A;  2VIL A;  4KEE A;  2W0I A;  2NUP A;  1AK7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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