2LLFA

Sixth gelsolin-like domain of villin in 5 mm cacl2
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
107
structure length
107
Chain Sequence
PRLFECSNKTGRFLATEIVDFTQDDLDENDVYLLDTWDQIFFWIGKGANESEKEAAAETAQEYLRSHPGSRDLDTPIIVVKQGFEPPTFTGWFMAWDPLCWSDRKSY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Gelsolin-like activation of villin: calcium sensitivity of the long helix in domain 6.
pubmed doi rcsb
molecule tags Structural protein
source organism Gallus gallus
molecule keywords Villin-1
total genus 15
structure length 107
sequence length 107
ec nomenclature
pdb deposition date 2011-11-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00626 Gelsolin Gelsolin repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 2llfA00
1NM1G 5KYXB 4PKGG 4PKHB 1WFSA 2NUPB 1PCXA 1Q8XA 2FH4A 1COFA 1QPVA 3FFNA 5KYUA 2W0IA 4CBUG 2VACA 1SVQA 2MP4A 5KYXA 2FGHA 3Q2BA 2NUPA 1WM4A 1P8ZG 1D0NA 2NUTB 1X67A 2FH1A 2VILA 3A5LS 1VKKA 1AK7A 3EGDA 2XF1A 3DAWB 3CJCG 3L50A 1VFQA 1AK6A 3FG7A 2MOTA 3EFOB 4Z94G 1Q8GA 1T44G 5KYYB 2XFAA 4BEX1 2MV2A 4LIZA 1M4JA 5FAEA 3EG9B 5IVUA 1CNUA 1MDUA 1DEJS 3EFOA 1WNJA 5KYYA 1TMWA 3EH1A 2VIKA 1C0FS 2QTVA 1PD0A 2L72A 1NLVG 1YVNG 4KEEA 1M2VB 4S10C 1CFYA 1D4XG 3TU5B 3A5MS 2I2QA 2NUTA 1SVYA 5HVKD 1T3XA 5DD2A 1KCQA 1T3YA 4JD2H 3A5OS 2FH3A 2LLFA 1SVRA 1V6FA 2LXXA 2FF6G 3FFKA 1H1VG 5KYWB 2FF3A 3EG9A 5KYNA 1UDMA 2LJ8A 5KYUB 1C0GS 1P8XA 2KVKA 1T2LA 1PD1A 3FG6A 5KYWA 2HD7A 4KEFA 1NPHA 1EQYS 1JHWA 1NMDG 1AHQA 1RGIG 3CI5G 1M2VA 2D8BA 3EGDB 1J72A 3EH2A 1M2OA 5A1MA 1ESVS 3EGXB 5L6WC 3CIPG 5HVKB 1HQZ1 3CJBG 4CBWG 3A5NS 4PKIG 2FH2A 5FAFA 4CBXG 4KEDA 1F7SA 1YAGG 1TVJA 3EGXA
chains in the Genus database with same CATH superfamily
1NM1G 5KYXB 4PKGG 4PKHB 1WFSA 2NUPB 1PCXA 1Q8XA 2FH4A 1COFA 1QPVA 3FFNA 5KYUA 2W0IA 4CBUG 2VACA 1SVQA 2MP4A 5KYXA 2FGHA 3Q2BA 2NUPA 1WM4A 1P8ZG 1D0NA 2NUTB 1X67A 2FH1A 2VILA 3A5LS 1VKKA 1AK7A 3EGDA 2XF1A 3DAWB 3CJCG 3L50A 1VFQA 1AK6A 3FG7A 2MOTA 3DA7A 3EFOB 4Z94G 1Q8GA 1T44G 5KYYB 2XFAA 4BEX1 2MV2A 4LIZA 1M4JA 5FAEA 3EG9B 5IVUA 1CNUA 1MDUA 1DEJS 3EFOA 1WNJA 5KYYA 1TMWA 3EH1A 2VIKA 1C0FS 2QTVA 1PD0A 2L72A 1NLVG 1YVNG 4KEEA 1M2VB 4S10C 1CFYA 1D4XG 3TU5B 3A5MS 2I2QA 2NUTA 1SVYA 5HVKD 1T3XA 5DD2A 1KCQA 1T3YA 4JD2H 3A5OS 2FH3A 2LLFA 1SVRA 1V6FA 2LXXA 2FF6G 3FFKA 1H1VG 5KYWB 2FF3A 3EG9A 5KYNA 1UDMA 2LJ8A 5KYUB 1C0GS 1P8XA 2KVKA 1T2LA 1PD1A 3FG6A 5KYWA 2HD7A 4KEFA 1NPHA 1EQYS 1JHWA 1NMDG 1AHQA 1RGIG 3CI5G 1M2VA 2D8BA 3EGDB 1J72A 3EH2A 1M2OA 5A1MA 1ESVS 3EGXB 5L6WC 3CIPG 5HVKB 1HQZ1 3CJBG 4CBWG 3A5NS 4PKIG 2FH2A 5FAFA 4CBXG 4KEDA 1F7SA 1YAGG 1TVJA 3EGXA
chains in the Genus database with same CATH topology
1NM1G 5KYXB 4PKGG 4PKHB 1WFSA 2NUPB 1PCXA 1Q8XA 2FH4A 1COFA 1QPVA 3FFNA 5KYUA 2W0IA 4CBUG 2VACA 1SVQA 2MP4A 5KYXA 2FGHA 3Q2BA 2NUPA 1WM4A 1P8ZG 1D0NA 2NUTB 1X67A 2FH1A 2VILA 3A5LS 1VKKA 1AK7A 3EGDA 2XF1A 3DAWB 3CJCG 3L50A 1VFQA 1AK6A 3FG7A 2MOTA 3DA7A 3EFOB 4Z94G 1Q8GA 1T44G 5KYYB 2XFAA 4BEX1 2MV2A 4LIZA 1M4JA 5FAEA 3EG9B 5IVUA 1CNUA 1MDUA 1DEJS 3EFOA 1WNJA 5KYYA 1TMWA 3EH1A 2VIKA 1C0FS 2QTVA 1PD0A 2L72A 1NLVG 1YVNG 4KEEA 1M2VB 4S10C 1CFYA 1D4XG 3TU5B 3A5MS 2I2QA 2NUTA 1SVYA 5HVKD 1T3XA 5DD2A 1KCQA 1T3YA 4JD2H 3A5OS 2FH3A 2LLFA 1SVRA 1V6FA 2LXXA 2FF6G 3FFKA 1H1VG 5KYWB 2FF3A 3EG9A 5KYNA 1UDMA 2LJ8A 5KYUB 1C0GS 1P8XA 2KVKA 1T2LA 1PD1A 3FG6A 5KYWA 2HD7A 4KEFA 1NPHA 1EQYS 1JHWA 1NMDG 1AHQA 1RGIG 3CI5G 1M2VA 2D8BA 3EGDB 1J72A 3EH2A 1M2OA 5A1MA 1ESVS 3EGXB 5L6WC 3CIPG 5HVKB 1HQZ1 3CJBG 4CBWG 3A5NS 4PKIG 2FH2A 5FAFA 4CBXG 4KEDA 1F7SA 1YAGG 1TVJA 3EGXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1NM1 G;  5KYX B;  4PKG G;  4PKH B;  1WFS A;  2NUP B;  1PCX A;  1Q8X A;  2FH4 A;  1COF A;  1QPV A;  3FFN A;  5KYU A;  2W0I A;  4CBU G;  2VAC A;  1SVQ A;  2MP4 A;  5KYX A;  2FGH A;  3Q2B A;  2NUP A;  1WM4 A;  1P8Z G;  1D0N A;  2NUT B;  1X67 A;  2FH1 A;  2VIL A;  3A5L S;  1VKK A;  1AK7 A;  3EGD A;  2XF1 A;  3DAW B;  3CJC G;  3L50 A;  1VFQ A;  1AK6 A;  3FG7 A;  2MOT A;  3EFO B;  4Z94 G;  1Q8G A;  1T44 G;  5KYY B;  2XFA A;  4BEX 1;  2MV2 A;  4LIZ A;  1M4J A;  5FAE A;  3EG9 B;  5IVU A;  1CNU A;  1MDU A;  1DEJ S;  3EFO A;  1WNJ A;  5KYY A;  1TMW A;  3EH1 A;  2VIK A;  1C0F S;  2QTV A;  1PD0 A;  2L72 A;  1NLV G;  1YVN G;  4KEE A;  1M2V B;  4S10 C;  1CFY A;  1D4X G;  3TU5 B;  3A5M S;  2I2Q A;  2NUT A;  1SVY A;  5HVK D;  1T3X A;  5DD2 A;  1KCQ A;  1T3Y A;  4JD2 H;  3A5O S;  2FH3 A;  2LLF A;  1SVR A;  1V6F A;  2LXX A;  2FF6 G;  3FFK A;  1H1V G;  5KYW B;  2FF3 A;  3EG9 A;  5KYN A;  1UDM A;  2LJ8 A;  5KYU B;  1C0G S;  1P8X A;  2KVK A;  1T2L A;  1PD1 A;  3FG6 A;  5KYW A;  2HD7 A;  4KEF A;  1NPH A;  1EQY S;  1JHW A;  1NMD G;  1AHQ A;  1RGI G;  3CI5 G;  1M2V A;  2D8B A;  3EGD B;  1J72 A;  3EH2 A;  1M2O A;  5A1M A;  1ESV S;  3EGX B;  5L6W C;  3CIP G;  5HVK B;  1HQZ 1;  3CJB G;  4CBW G;  3A5N S;  4PKI G;  2FH2 A;  5FAF A;  4CBX G;  4KED A;  1F7S A;  1YAG G;  1TVJ A;  3EGX A; 
#chains in the Genus database with same CATH topology
 1NM1 G;  5KYX B;  4PKG G;  4PKH B;  1WFS A;  2NUP B;  1PCX A;  1Q8X A;  2FH4 A;  1COF A;  1QPV A;  3FFN A;  5KYU A;  2W0I A;  4CBU G;  2VAC A;  1SVQ A;  2MP4 A;  5KYX A;  2FGH A;  3Q2B A;  2NUP A;  1WM4 A;  1P8Z G;  1D0N A;  2NUT B;  1X67 A;  2FH1 A;  2VIL A;  3A5L S;  1VKK A;  1AK7 A;  3EGD A;  2XF1 A;  3DAW B;  3CJC G;  3L50 A;  1VFQ A;  1AK6 A;  3FG7 A;  2MOT A;  3DA7 A;  3EFO B;  4Z94 G;  1Q8G A;  1T44 G;  5KYY B;  2XFA A;  4BEX 1;  2MV2 A;  4LIZ A;  1M4J A;  5FAE A;  3EG9 B;  5IVU A;  1CNU A;  1MDU A;  1DEJ S;  3EFO A;  1WNJ A;  5KYY A;  1TMW A;  3EH1 A;  2VIK A;  1C0F S;  2QTV A;  1PD0 A;  2L72 A;  1NLV G;  1YVN G;  4KEE A;  1M2V B;  4S10 C;  1CFY A;  1D4X G;  3TU5 B;  3A5M S;  2I2Q A;  2NUT A;  1SVY A;  5HVK D;  1T3X A;  5DD2 A;  1KCQ A;  1T3Y A;  4JD2 H;  3A5O S;  2FH3 A;  2LLF A;  1SVR A;  1V6F A;  2LXX A;  2FF6 G;  3FFK A;  1H1V G;  5KYW B;  2FF3 A;  3EG9 A;  5KYN A;  1UDM A;  2LJ8 A;  5KYU B;  1C0G S;  1P8X A;  2KVK A;  1T2L A;  1PD1 A;  3FG6 A;  5KYW A;  2HD7 A;  4KEF A;  1NPH A;  1EQY S;  1JHW A;  1NMD G;  1AHQ A;  1RGI G;  3CI5 G;  1M2V A;  2D8B A;  3EGD B;  1J72 A;  3EH2 A;  1M2O A;  5A1M A;  1ESV S;  3EGX B;  5L6W C;  3CIP G;  5HVK B;  1HQZ 1;  3CJB G;  4CBW G;  3A5N S;  4PKI G;  2FH2 A;  5FAF A;  4CBX G;  4KED A;  1F7S A;  1YAG G;  1TVJ A;  3EGX A; 
#chains in the Genus database with same CATH homology
 1NM1 G;  5KYX B;  4PKG G;  4PKH B;  1WFS A;  2NUP B;  1PCX A;  1Q8X A;  2FH4 A;  1COF A;  1QPV A;  3FFN A;  5KYU A;  2W0I A;  4CBU G;  2VAC A;  1SVQ A;  2MP4 A;  5KYX A;  2FGH A;  3Q2B A;  2NUP A;  1WM4 A;  1P8Z G;  1D0N A;  2NUT B;  1X67 A;  2FH1 A;  2VIL A;  3A5L S;  1VKK A;  1AK7 A;  3EGD A;  2XF1 A;  3DAW B;  3CJC G;  3L50 A;  1VFQ A;  1AK6 A;  3FG7 A;  2MOT A;  3DA7 A;  3EFO B;  4Z94 G;  1Q8G A;  1T44 G;  5KYY B;  2XFA A;  4BEX 1;  2MV2 A;  4LIZ A;  1M4J A;  5FAE A;  3EG9 B;  5IVU A;  1CNU A;  1MDU A;  1DEJ S;  3EFO A;  1WNJ A;  5KYY A;  1TMW A;  3EH1 A;  2VIK A;  1C0F S;  2QTV A;  1PD0 A;  2L72 A;  1NLV G;  1YVN G;  4KEE A;  1M2V B;  4S10 C;  1CFY A;  1D4X G;  3TU5 B;  3A5M S;  2I2Q A;  2NUT A;  1SVY A;  5HVK D;  1T3X A;  5DD2 A;  1KCQ A;  1T3Y A;  4JD2 H;  3A5O S;  2FH3 A;  2LLF A;  1SVR A;  1V6F A;  2LXX A;  2FF6 G;  3FFK A;  1H1V G;  5KYW B;  2FF3 A;  3EG9 A;  5KYN A;  1UDM A;  2LJ8 A;  5KYU B;  1C0G S;  1P8X A;  2KVK A;  1T2L A;  1PD1 A;  3FG6 A;  5KYW A;  2HD7 A;  4KEF A;  1NPH A;  1EQY S;  1JHW A;  1NMD G;  1AHQ A;  1RGI G;  3CI5 G;  1M2V A;  2D8B A;  3EGD B;  1J72 A;  3EH2 A;  1M2O A;  5A1M A;  1ESV S;  3EGX B;  5L6W C;  3CIP G;  5HVK B;  1HQZ 1;  3CJB G;  4CBW G;  3A5N S;  4PKI G;  2FH2 A;  5FAF A;  4CBX G;  4KED A;  1F7S A;  1YAG G;  1TVJ A;  3EGX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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