2LLFA

Sixth gelsolin-like domain of villin in 5 mm cacl2
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
107
structure length
107
Chain Sequence
PRLFECSNKTGRFLATEIVDFTQDDLDENDVYLLDTWDQIFFWIGKGANESEKEAAAETAQEYLRSHPGSRDLDTPIIVVKQGFEPPTFTGWFMAWDPLCWSDRKSY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Gelsolin-like activation of villin: calcium sensitivity of the long helix in domain 6.
pubmed doi rcsb
molecule tags Structural protein
source organism Gallus gallus
molecule keywords Villin-1
total genus 15
structure length 107
sequence length 107
ec nomenclature
pdb deposition date 2011-11-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00626 Gelsolin Gelsolin repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 2llfA00
2NUPA 2VACA 1X67A 3L50A 3Q2BA 1Q8XA 3CJCG 5HVKB 2VIKA 3TU5B 1T3YA 5FAFA 2LXXA 1T44G 1JHWA 1Q8GA 1WM4A 1AK7A 1C0FS 1PD1A 5KYWB 4KEFA 1T2LA 1V6FA 1TVJA 1MDUA 2FF3A 5L6WC 3EH1A 3FG6A 1EQYS 1COFA 2W0IA 1CNUA 1NMDG 5KYWA 1D0NA 1KCQA 1F7SA 3A5LS 4PKHB 1M2VB 2MP4A 3EG9B 1NLVG 1M4JA 1P8XA 1SVQA 1M2OA 1QPVA 2VILA 1P8ZG 3FG7A 4CBUG 1M2VA 4CBXG 3EG9A 3A5NS 2FGHA 1RGIG 3EFOB 3CJBG 4PKIG 4LIZA 1SVYA 2XF1A 3CIPG 3A5MS 3DAWB 2L72A 5KYXA 1PCXA 3EFOA 1YVNG 2HD7A 2XFAA 5DD2A 1J72A 1AK6A 3A5OS 1HQZ1 3EH2A 1VFQA 4JD2H 5KYUB 2FH3A 3FFKA 2NUTA 5KYYA 1SVRA 2LJ8A 2MV2A 5KYXB 5KYNA 2FH2A 5KYUA 1AHQA 1H1VG 2FF6G 3CI5G 4S10C 1D4XG 4BEX1 4KEDA 5IVUA 4CBWG 3EGDA 1ESVS 3EGXB 2NUTB 1WFSA 2KVKA 4KEEA 1C0GS 5KYYB 1WNJA 5A1MA 1VKKA 2QTVA 1TMWA 1DEJS 1CFYA 3EGXA 2D8BA 2I2QA 2NUPB 1NPHA 4Z94G 2FH4A 5FAEA 2LLFA 1NM1G 3EGDB 5HVKD 2FH1A 2MOTA 1YAGG 1PD0A 1UDMA 4PKGG 3FFNA 1T3XA
chains in the Genus database with same CATH superfamily
2NUPA 2VACA 1X67A 3L50A 3Q2BA 1Q8XA 3CJCG 5HVKB 2VIKA 3TU5B 1T3YA 5FAFA 2LXXA 1T44G 1JHWA 1Q8GA 1WM4A 1AK7A 1C0FS 1PD1A 5KYWB 4KEFA 1T2LA 1V6FA 1TVJA 1MDUA 2FF3A 5L6WC 3EH1A 3FG6A 1EQYS 1COFA 2W0IA 1CNUA 1NMDG 5KYWA 1D0NA 1KCQA 1F7SA 3A5LS 4PKHB 1M2VB 2MP4A 3EG9B 1NLVG 1M4JA 1P8XA 1SVQA 1M2OA 1QPVA 2VILA 1P8ZG 3FG7A 4CBUG 1M2VA 4CBXG 3EG9A 3A5NS 2FGHA 1RGIG 3EFOB 3CJBG 4PKIG 4LIZA 1SVYA 2XF1A 3CIPG 3A5MS 3DAWB 2L72A 5KYXA 1PCXA 3EFOA 1YVNG 2HD7A 2XFAA 5DD2A 1J72A 1AK6A 3A5OS 1HQZ1 3EH2A 1VFQA 4JD2H 5KYUB 2FH3A 3FFKA 2NUTA 5KYYA 1SVRA 2LJ8A 2MV2A 5KYXB 5KYNA 2FH2A 5KYUA 1AHQA 1H1VG 2FF6G 3CI5G 4S10C 1D4XG 4BEX1 4KEDA 5IVUA 4CBWG 3EGDA 1ESVS 3EGXB 2NUTB 1WFSA 2KVKA 4KEEA 1C0GS 5KYYB 1WNJA 5A1MA 1VKKA 2QTVA 1TMWA 1DEJS 1CFYA 3EGXA 2D8BA 3DA7A 2I2QA 2NUPB 1NPHA 4Z94G 2FH4A 5FAEA 2LLFA 1NM1G 3EGDB 5HVKD 2FH1A 2MOTA 1YAGG 1PD0A 1UDMA 4PKGG 3FFNA 1T3XA
chains in the Genus database with same CATH topology
2NUPA 2VACA 1X67A 3L50A 3Q2BA 1Q8XA 3CJCG 5HVKB 2VIKA 3TU5B 1T3YA 5FAFA 2LXXA 1T44G 1JHWA 1Q8GA 1WM4A 1AK7A 1C0FS 1PD1A 5KYWB 4KEFA 1T2LA 1V6FA 1TVJA 1MDUA 2FF3A 5L6WC 3EH1A 3FG6A 1EQYS 1COFA 2W0IA 1CNUA 1NMDG 5KYWA 1D0NA 1KCQA 1F7SA 3A5LS 4PKHB 1M2VB 2MP4A 3EG9B 1NLVG 1M4JA 1P8XA 1SVQA 1M2OA 1QPVA 2VILA 1P8ZG 3FG7A 4CBUG 1M2VA 4CBXG 3EG9A 3A5NS 2FGHA 1RGIG 3EFOB 3CJBG 4PKIG 4LIZA 1SVYA 2XF1A 3CIPG 3A5MS 3DAWB 2L72A 5KYXA 1PCXA 3EFOA 1YVNG 2HD7A 2XFAA 5DD2A 1J72A 1AK6A 3A5OS 1HQZ1 3EH2A 1VFQA 4JD2H 5KYUB 2FH3A 3FFKA 2NUTA 5KYYA 1SVRA 2LJ8A 2MV2A 5KYXB 5KYNA 2FH2A 5KYUA 1AHQA 1H1VG 2FF6G 3CI5G 4S10C 1D4XG 4BEX1 4KEDA 5IVUA 4CBWG 3EGDA 1ESVS 3EGXB 2NUTB 1WFSA 2KVKA 4KEEA 1C0GS 5KYYB 1WNJA 5A1MA 1VKKA 2QTVA 1TMWA 1DEJS 1CFYA 3EGXA 2D8BA 3DA7A 2I2QA 2NUPB 1NPHA 4Z94G 2FH4A 5FAEA 2LLFA 1NM1G 3EGDB 5HVKD 2FH1A 2MOTA 1YAGG 1PD0A 1UDMA 4PKGG 3FFNA 1T3XA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NUP A;  2VAC A;  1X67 A;  3L50 A;  3Q2B A;  1Q8X A;  3CJC G;  5HVK B;  2VIK A;  3TU5 B;  1T3Y A;  5FAF A;  2LXX A;  1T44 G;  1JHW A;  1Q8G A;  1WM4 A;  1AK7 A;  1C0F S;  1PD1 A;  5KYW B;  4KEF A;  1T2L A;  1V6F A;  1TVJ A;  1MDU A;  2FF3 A;  5L6W C;  3EH1 A;  3FG6 A;  1EQY S;  1COF A;  2W0I A;  1CNU A;  1NMD G;  5KYW A;  1D0N A;  1KCQ A;  1F7S A;  3A5L S;  4PKH B;  1M2V B;  2MP4 A;  3EG9 B;  1NLV G;  1M4J A;  1P8X A;  1SVQ A;  1M2O A;  1QPV A;  2VIL A;  1P8Z G;  3FG7 A;  4CBU G;  1M2V A;  4CBX G;  3EG9 A;  3A5N S;  2FGH A;  1RGI G;  3EFO B;  3CJB G;  4PKI G;  4LIZ A;  1SVY A;  2XF1 A;  3CIP G;  3A5M S;  3DAW B;  2L72 A;  5KYX A;  1PCX A;  3EFO A;  1YVN G;  2HD7 A;  2XFA A;  5DD2 A;  1J72 A;  1AK6 A;  3A5O S;  1HQZ 1;  3EH2 A;  1VFQ A;  4JD2 H;  5KYU B;  2FH3 A;  3FFK A;  2NUT A;  5KYY A;  1SVR A;  2LJ8 A;  2MV2 A;  5KYX B;  5KYN A;  2FH2 A;  5KYU A;  1AHQ A;  1H1V G;  2FF6 G;  3CI5 G;  4S10 C;  1D4X G;  4BEX 1;  4KED A;  5IVU A;  4CBW G;  3EGD A;  1ESV S;  3EGX B;  2NUT B;  1WFS A;  2KVK A;  4KEE A;  1C0G S;  5KYY B;  1WNJ A;  5A1M A;  1VKK A;  2QTV A;  1TMW A;  1DEJ S;  1CFY A;  3EGX A;  2D8B A;  2I2Q A;  2NUP B;  1NPH A;  4Z94 G;  2FH4 A;  5FAE A;  2LLF A;  1NM1 G;  3EGD B;  5HVK D;  2FH1 A;  2MOT A;  1YAG G;  1PD0 A;  1UDM A;  4PKG G;  3FFN A;  1T3X A; 
#chains in the Genus database with same CATH topology
 2NUP A;  2VAC A;  1X67 A;  3L50 A;  3Q2B A;  1Q8X A;  3CJC G;  5HVK B;  2VIK A;  3TU5 B;  1T3Y A;  5FAF A;  2LXX A;  1T44 G;  1JHW A;  1Q8G A;  1WM4 A;  1AK7 A;  1C0F S;  1PD1 A;  5KYW B;  4KEF A;  1T2L A;  1V6F A;  1TVJ A;  1MDU A;  2FF3 A;  5L6W C;  3EH1 A;  3FG6 A;  1EQY S;  1COF A;  2W0I A;  1CNU A;  1NMD G;  5KYW A;  1D0N A;  1KCQ A;  1F7S A;  3A5L S;  4PKH B;  1M2V B;  2MP4 A;  3EG9 B;  1NLV G;  1M4J A;  1P8X A;  1SVQ A;  1M2O A;  1QPV A;  2VIL A;  1P8Z G;  3FG7 A;  4CBU G;  1M2V A;  4CBX G;  3EG9 A;  3A5N S;  2FGH A;  1RGI G;  3EFO B;  3CJB G;  4PKI G;  4LIZ A;  1SVY A;  2XF1 A;  3CIP G;  3A5M S;  3DAW B;  2L72 A;  5KYX A;  1PCX A;  3EFO A;  1YVN G;  2HD7 A;  2XFA A;  5DD2 A;  1J72 A;  1AK6 A;  3A5O S;  1HQZ 1;  3EH2 A;  1VFQ A;  4JD2 H;  5KYU B;  2FH3 A;  3FFK A;  2NUT A;  5KYY A;  1SVR A;  2LJ8 A;  2MV2 A;  5KYX B;  5KYN A;  2FH2 A;  5KYU A;  1AHQ A;  1H1V G;  2FF6 G;  3CI5 G;  4S10 C;  1D4X G;  4BEX 1;  4KED A;  5IVU A;  4CBW G;  3EGD A;  1ESV S;  3EGX B;  2NUT B;  1WFS A;  2KVK A;  4KEE A;  1C0G S;  5KYY B;  1WNJ A;  5A1M A;  1VKK A;  2QTV A;  1TMW A;  1DEJ S;  1CFY A;  3EGX A;  2D8B A;  3DA7 A;  2I2Q A;  2NUP B;  1NPH A;  4Z94 G;  2FH4 A;  5FAE A;  2LLF A;  1NM1 G;  3EGD B;  5HVK D;  2FH1 A;  2MOT A;  1YAG G;  1PD0 A;  1UDM A;  4PKG G;  3FFN A;  1T3X A; 
#chains in the Genus database with same CATH homology
 2NUP A;  2VAC A;  1X67 A;  3L50 A;  3Q2B A;  1Q8X A;  3CJC G;  5HVK B;  2VIK A;  3TU5 B;  1T3Y A;  5FAF A;  2LXX A;  1T44 G;  1JHW A;  1Q8G A;  1WM4 A;  1AK7 A;  1C0F S;  1PD1 A;  5KYW B;  4KEF A;  1T2L A;  1V6F A;  1TVJ A;  1MDU A;  2FF3 A;  5L6W C;  3EH1 A;  3FG6 A;  1EQY S;  1COF A;  2W0I A;  1CNU A;  1NMD G;  5KYW A;  1D0N A;  1KCQ A;  1F7S A;  3A5L S;  4PKH B;  1M2V B;  2MP4 A;  3EG9 B;  1NLV G;  1M4J A;  1P8X A;  1SVQ A;  1M2O A;  1QPV A;  2VIL A;  1P8Z G;  3FG7 A;  4CBU G;  1M2V A;  4CBX G;  3EG9 A;  3A5N S;  2FGH A;  1RGI G;  3EFO B;  3CJB G;  4PKI G;  4LIZ A;  1SVY A;  2XF1 A;  3CIP G;  3A5M S;  3DAW B;  2L72 A;  5KYX A;  1PCX A;  3EFO A;  1YVN G;  2HD7 A;  2XFA A;  5DD2 A;  1J72 A;  1AK6 A;  3A5O S;  1HQZ 1;  3EH2 A;  1VFQ A;  4JD2 H;  5KYU B;  2FH3 A;  3FFK A;  2NUT A;  5KYY A;  1SVR A;  2LJ8 A;  2MV2 A;  5KYX B;  5KYN A;  2FH2 A;  5KYU A;  1AHQ A;  1H1V G;  2FF6 G;  3CI5 G;  4S10 C;  1D4X G;  4BEX 1;  4KED A;  5IVU A;  4CBW G;  3EGD A;  1ESV S;  3EGX B;  2NUT B;  1WFS A;  2KVK A;  4KEE A;  1C0G S;  5KYY B;  1WNJ A;  5A1M A;  1VKK A;  2QTV A;  1TMW A;  1DEJ S;  1CFY A;  3EGX A;  2D8B A;  3DA7 A;  2I2Q A;  2NUP B;  1NPH A;  4Z94 G;  2FH4 A;  5FAE A;  2LLF A;  1NM1 G;  3EGD B;  5HVK D;  2FH1 A;  2MOT A;  1YAG G;  1PD0 A;  1UDM A;  4PKG G;  3FFN A;  1T3X A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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