3FG6A

Structure of the c-terminus of adseverin
Total Genus 86
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
320
structure length
296
Chain Sequence
GKVEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTYPRGQIIYTWQGANATRDELTTSAFLTVQLDRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIYPTRLFQVRRNLASITRIVEVDVDANSLNSNDVFVLKLPQNSGYIWVGKGASQEEEKGAEYVASVLKCKTLRIQEGEEPEEFWNSLGGKKDYQTSPLLETQAEDHPPRLYGCSNKTGRFVIEEIPGEFTQDDLAEDDVMLLDAWEQIFIWIGKDANEVEKKESLKSAKMYLTPIVIIKQGHEPPTFTGWFLGWDSSKW
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The crystal structure of the C-terminus of adseverin reveals the actin-binding interface.
pubmed doi rcsb
molecule tags Actin-binding protein
source organism Homo sapiens
molecule keywords Adseverin
total genus 86
structure length 296
sequence length 320
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature
pdb deposition date 2008-12-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00626 Gelsolin Gelsolin repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 3fg6A03
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 3fg6A02
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 3fg6A01
3A5NS 1MDUA 5KYXB 1D4XG 1CFYA 4BEX1 1ESVS 3EFOB 1AK7A 4CBWG 1UDMA 2FH4A 1P8ZG 1T3YA 2MP4A 2I2QA 1SVYA 2VACA 5HVKB 1C0GS 4S10C 5DD2A 3EGXA 4PKIG 3FFKA 1T3XA 5FAEA 5KYUB 1TMWA 3EH2A 1YAGG 2QTVA 1NMDG 3EH1A 1NLVG 3CJBG 5KYWA 5KYNA 1YVNG 3L50A 5L6WC 4KEEA 1M2OA 3EG9B 5A1MA 1M2VA 4CBXG 2NUTB 1NPHA 2NUPB 1SVQA 5KYYA 1Q8XA 1HQZ1 1F7SA 2LXXA 1AK6A 3CJCG 1AHQA 5IVUA 3EGDA 2L72A 1WNJA 2LJ8A 3CIPG 4KEDA 1KCQA 5KYXA 4CBUG 1SVRA 3A5OS 2W0IA 1TVJA 1Q8GA 3EFOA 2KVKA 1T44G 1VKKA 2LLFA 3FFNA 4PKHB 1WFSA 3TU5B 1T2LA 3CI5G 3FG7A 1RGIG 1C0FS 3A5LS 1PD1A 1NM1G 2VIKA 1DEJS 1CNUA 3EGXB 1QPVA 3FG6A 2FH2A 2FF3A 1M4JA 2D8BA 5KYUA 2MOTA 1H1VG 2FH3A 2FGHA 1PCXA 1V6FA 1X67A 4JD2H 5HVKD 1PD0A 5KYWB 2MV2A 3DAWB 4LIZA 2FH1A 1JHWA 1P8XA 2FF6G 1M2VB 3A5MS 4KEFA 1J72A 3EG9A 1D0NA 5KYYB 2NUTA 5FAFA 2NUPA 3EGDB 2XF1A 1VFQA 3Q2BA 4Z94G 1WM4A 2HD7A 2VILA 4PKGG 2XFAA 1COFA 1EQYS
chains in the Genus database with same CATH superfamily
3A5NS 1MDUA 3DA7A 5KYXB 1D4XG 1CFYA 4BEX1 1ESVS 3EFOB 1AK7A 4CBWG 1UDMA 2FH4A 1P8ZG 1T3YA 2MP4A 2I2QA 1SVYA 2VACA 5HVKB 1C0GS 4S10C 5DD2A 3EGXA 4PKIG 3FFKA 1T3XA 5FAEA 5KYUB 1TMWA 3EH2A 1YAGG 2QTVA 1NMDG 3EH1A 1NLVG 3CJBG 5KYWA 5KYNA 1YVNG 3L50A 5L6WC 4KEEA 1M2OA 3EG9B 5A1MA 1M2VA 4CBXG 2NUTB 1NPHA 2NUPB 1SVQA 5KYYA 1Q8XA 1HQZ1 1F7SA 2LXXA 1AK6A 3CJCG 1AHQA 5IVUA 3EGDA 2L72A 1WNJA 2LJ8A 3CIPG 4KEDA 1KCQA 5KYXA 4CBUG 1SVRA 3A5OS 2W0IA 1TVJA 1Q8GA 3EFOA 2KVKA 1T44G 1VKKA 2LLFA 3FFNA 4PKHB 1WFSA 3TU5B 1T2LA 3CI5G 3FG7A 1RGIG 1C0FS 3A5LS 1PD1A 1NM1G 2VIKA 1DEJS 1CNUA 3EGXB 1QPVA 3FG6A 2FH2A 2FF3A 1M4JA 2D8BA 5KYUA 2MOTA 1H1VG 2FH3A 2FGHA 1PCXA 1V6FA 1X67A 4JD2H 5HVKD 1PD0A 5KYWB 2MV2A 3DAWB 4LIZA 2FH1A 1JHWA 1P8XA 2FF6G 1M2VB 3A5MS 4KEFA 1J72A 3EG9A 1D0NA 5KYYB 2NUTA 5FAFA 2NUPA 3EGDB 2XF1A 1VFQA 3Q2BA 4Z94G 1WM4A 2HD7A 2VILA 4PKGG 2XFAA 1COFA 1EQYS
chains in the Genus database with same CATH topology
3A5NS 1MDUA 3DA7A 5KYXB 1D4XG 1CFYA 4BEX1 1ESVS 3EFOB 1AK7A 4CBWG 1UDMA 2FH4A 1P8ZG 1T3YA 2MP4A 2I2QA 1SVYA 2VACA 5HVKB 1C0GS 4S10C 5DD2A 3EGXA 4PKIG 3FFKA 1T3XA 5FAEA 5KYUB 1TMWA 3EH2A 1YAGG 2QTVA 1NMDG 3EH1A 1NLVG 3CJBG 5KYWA 5KYNA 1YVNG 3L50A 5L6WC 4KEEA 1M2OA 3EG9B 5A1MA 1M2VA 4CBXG 2NUTB 1NPHA 2NUPB 1SVQA 5KYYA 1Q8XA 1HQZ1 1F7SA 2LXXA 1AK6A 3CJCG 1AHQA 5IVUA 3EGDA 2L72A 1WNJA 2LJ8A 3CIPG 4KEDA 1KCQA 5KYXA 4CBUG 1SVRA 3A5OS 2W0IA 1TVJA 1Q8GA 3EFOA 2KVKA 1T44G 1VKKA 2LLFA 3FFNA 4PKHB 1WFSA 3TU5B 1T2LA 3CI5G 3FG7A 1RGIG 1C0FS 3A5LS 1PD1A 1NM1G 2VIKA 1DEJS 1CNUA 3EGXB 1QPVA 3FG6A 2FH2A 2FF3A 1M4JA 2D8BA 5KYUA 2MOTA 1H1VG 2FH3A 2FGHA 1PCXA 1V6FA 1X67A 4JD2H 5HVKD 1PD0A 5KYWB 2MV2A 3DAWB 4LIZA 2FH1A 1JHWA 1P8XA 2FF6G 1M2VB 3A5MS 4KEFA 1J72A 3EG9A 1D0NA 5KYYB 2NUTA 5FAFA 2NUPA 3EGDB 2XF1A 1VFQA 3Q2BA 4Z94G 1WM4A 2HD7A 2VILA 4PKGG 2XFAA 1COFA 1EQYS
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3A5N S;  1MDU A;  5KYX B;  1D4X G;  1CFY A;  4BEX 1;  1ESV S;  3EFO B;  1AK7 A;  4CBW G;  1UDM A;  2FH4 A;  1P8Z G;  1T3Y A;  2MP4 A;  2I2Q A;  1SVY A;  2VAC A;  5HVK B;  1C0G S;  4S10 C;  5DD2 A;  3EGX A;  4PKI G;  3FFK A;  1T3X A;  5FAE A;  5KYU B;  1TMW A;  3EH2 A;  1YAG G;  2QTV A;  1NMD G;  3EH1 A;  1NLV G;  3CJB G;  5KYW A;  5KYN A;  1YVN G;  3L50 A;  5L6W C;  4KEE A;  1M2O A;  3EG9 B;  5A1M A;  1M2V A;  4CBX G;  2NUT B;  1NPH A;  2NUP B;  1SVQ A;  5KYY A;  1Q8X A;  1HQZ 1;  1F7S A;  2LXX A;  1AK6 A;  3CJC G;  1AHQ A;  5IVU A;  3EGD A;  2L72 A;  1WNJ A;  2LJ8 A;  3CIP G;  4KED A;  1KCQ A;  5KYX A;  4CBU G;  1SVR A;  3A5O S;  2W0I A;  1TVJ A;  1Q8G A;  3EFO A;  2KVK A;  1T44 G;  1VKK A;  2LLF A;  3FFN A;  4PKH B;  1WFS A;  3TU5 B;  1T2L A;  3CI5 G;  3FG7 A;  1RGI G;  1C0F S;  3A5L S;  1PD1 A;  1NM1 G;  2VIK A;  1DEJ S;  1CNU A;  3EGX B;  1QPV A;  3FG6 A;  2FH2 A;  2FF3 A;  1M4J A;  2D8B A;  5KYU A;  2MOT A;  1H1V G;  2FH3 A;  2FGH A;  1PCX A;  1V6F A;  1X67 A;  4JD2 H;  5HVK D;  1PD0 A;  5KYW B;  2MV2 A;  3DAW B;  4LIZ A;  2FH1 A;  1JHW A;  1P8X A;  2FF6 G;  1M2V B;  3A5M S;  4KEF A;  1J72 A;  3EG9 A;  1D0N A;  5KYY B;  2NUT A;  5FAF A;  2NUP A;  3EGD B;  2XF1 A;  1VFQ A;  3Q2B A;  4Z94 G;  1WM4 A;  2HD7 A;  2VIL A;  4PKG G;  2XFA A;  1COF A;  1EQY S; 
#chains in the Genus database with same CATH topology
 3A5N S;  1MDU A;  3DA7 A;  5KYX B;  1D4X G;  1CFY A;  4BEX 1;  1ESV S;  3EFO B;  1AK7 A;  4CBW G;  1UDM A;  2FH4 A;  1P8Z G;  1T3Y A;  2MP4 A;  2I2Q A;  1SVY A;  2VAC A;  5HVK B;  1C0G S;  4S10 C;  5DD2 A;  3EGX A;  4PKI G;  3FFK A;  1T3X A;  5FAE A;  5KYU B;  1TMW A;  3EH2 A;  1YAG G;  2QTV A;  1NMD G;  3EH1 A;  1NLV G;  3CJB G;  5KYW A;  5KYN A;  1YVN G;  3L50 A;  5L6W C;  4KEE A;  1M2O A;  3EG9 B;  5A1M A;  1M2V A;  4CBX G;  2NUT B;  1NPH A;  2NUP B;  1SVQ A;  5KYY A;  1Q8X A;  1HQZ 1;  1F7S A;  2LXX A;  1AK6 A;  3CJC G;  1AHQ A;  5IVU A;  3EGD A;  2L72 A;  1WNJ A;  2LJ8 A;  3CIP G;  4KED A;  1KCQ A;  5KYX A;  4CBU G;  1SVR A;  3A5O S;  2W0I A;  1TVJ A;  1Q8G A;  3EFO A;  2KVK A;  1T44 G;  1VKK A;  2LLF A;  3FFN A;  4PKH B;  1WFS A;  3TU5 B;  1T2L A;  3CI5 G;  3FG7 A;  1RGI G;  1C0F S;  3A5L S;  1PD1 A;  1NM1 G;  2VIK A;  1DEJ S;  1CNU A;  3EGX B;  1QPV A;  3FG6 A;  2FH2 A;  2FF3 A;  1M4J A;  2D8B A;  5KYU A;  2MOT A;  1H1V G;  2FH3 A;  2FGH A;  1PCX A;  1V6F A;  1X67 A;  4JD2 H;  5HVK D;  1PD0 A;  5KYW B;  2MV2 A;  3DAW B;  4LIZ A;  2FH1 A;  1JHW A;  1P8X A;  2FF6 G;  1M2V B;  3A5M S;  4KEF A;  1J72 A;  3EG9 A;  1D0N A;  5KYY B;  2NUT A;  5FAF A;  2NUP A;  3EGD B;  2XF1 A;  1VFQ A;  3Q2B A;  4Z94 G;  1WM4 A;  2HD7 A;  2VIL A;  4PKG G;  2XFA A;  1COF A;  1EQY S; 
#chains in the Genus database with same CATH homology
 3A5N S;  1MDU A;  3DA7 A;  5KYX B;  1D4X G;  1CFY A;  4BEX 1;  1ESV S;  3EFO B;  1AK7 A;  4CBW G;  1UDM A;  2FH4 A;  1P8Z G;  1T3Y A;  2MP4 A;  2I2Q A;  1SVY A;  2VAC A;  5HVK B;  1C0G S;  4S10 C;  5DD2 A;  3EGX A;  4PKI G;  3FFK A;  1T3X A;  5FAE A;  5KYU B;  1TMW A;  3EH2 A;  1YAG G;  2QTV A;  1NMD G;  3EH1 A;  1NLV G;  3CJB G;  5KYW A;  5KYN A;  1YVN G;  3L50 A;  5L6W C;  4KEE A;  1M2O A;  3EG9 B;  5A1M A;  1M2V A;  4CBX G;  2NUT B;  1NPH A;  2NUP B;  1SVQ A;  5KYY A;  1Q8X A;  1HQZ 1;  1F7S A;  2LXX A;  1AK6 A;  3CJC G;  1AHQ A;  5IVU A;  3EGD A;  2L72 A;  1WNJ A;  2LJ8 A;  3CIP G;  4KED A;  1KCQ A;  5KYX A;  4CBU G;  1SVR A;  3A5O S;  2W0I A;  1TVJ A;  1Q8G A;  3EFO A;  2KVK A;  1T44 G;  1VKK A;  2LLF A;  3FFN A;  4PKH B;  1WFS A;  3TU5 B;  1T2L A;  3CI5 G;  3FG7 A;  1RGI G;  1C0F S;  3A5L S;  1PD1 A;  1NM1 G;  2VIK A;  1DEJ S;  1CNU A;  3EGX B;  1QPV A;  3FG6 A;  2FH2 A;  2FF3 A;  1M4J A;  2D8B A;  5KYU A;  2MOT A;  1H1V G;  2FH3 A;  2FGH A;  1PCX A;  1V6F A;  1X67 A;  4JD2 H;  5HVK D;  1PD0 A;  5KYW B;  2MV2 A;  3DAW B;  4LIZ A;  2FH1 A;  1JHW A;  1P8X A;  2FF6 G;  1M2V B;  3A5M S;  4KEF A;  1J72 A;  3EG9 A;  1D0N A;  5KYY B;  2NUT A;  5FAF A;  2NUP A;  3EGD B;  2XF1 A;  1VFQ A;  3Q2B A;  4Z94 G;  1WM4 A;  2HD7 A;  2VIL A;  4PKG G;  2XFA A;  1COF A;  1EQY S; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...