3FG6A

Structure of the c-terminus of adseverin
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
320
structure length
296
Chain Sequence
GKVEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTYPRGQIIYTWQGANATRDELTTSAFLTVQLDRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIYPTRLFQVRRNLASITRIVEVDVDANSLNSNDVFVLKLPQNSGYIWVGKGASQEEEKGAEYVASVLKCKTLRIQEGEEPEEFWNSLGGKKDYQTSPLLETQAEDHPPRLYGCSNKTGRFVIEEIPGEFTQDDLAEDDVMLLDAWEQIFIWIGKDANEVEKKESLKSAKMYLTPIVIIKQGHEPPTFTGWFLGWDSSKW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The crystal structure of the C-terminus of adseverin reveals the actin-binding interface.
pubmed doi rcsb
molecule tags Actin-binding protein
source organism Homo sapiens
molecule keywords Adseverin
total genus 86
structure length 296
sequence length 320
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature
pdb deposition date 2008-12-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00626 Gelsolin Gelsolin repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 3fg6A03
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 3fg6A02
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 3fg6A01
2D8BA 3CJBG 1TVJA 2FH1A 1T3YA 3DAWB 3EGXA 2MP4A 4KEEA 3EGXB 1C0FS 5KYXA 2LLFA 3FG7A 5A1MA 1COFA 5KYXB 2NUPA 1T2LA 1T44G 2NUPB 1JHWA 1V6FA 5DD2A 4CBXG 2W0IA 1VKKA 1C0GS 1YVNG 2LXXA 2VACA 1M2OA 3FG6A 5HVKD 1H1VG 2VIKA 3EG9A 3EGDA 3EG9B 3EH1A 3EGDB 1PD1A 1Q8GA 2LJ8A 2MOTA 3FFKA 2QTVA 1WFSA 1NPHA 1MDUA 3L50A 1EQYS 2HD7A 1SVYA 4KEDA 5KYNA 4PKIG 3TU5B 1VFQA 1AK6A 1P8ZG 1J72A 4S10C 5FAFA 3A5NS 1PCXA 1QPVA 1Q8XA 1D0NA 2L72A 3EFOA 1T3XA 3EFOB 5HVKB 2I2QA 1AHQA 4PKGG 3A5OS 3CIPG 2XFAA 5KYUA 1NLVG 4JD2H 5KYUB 2FH4A 1SVQA 1D4XG 1P8XA 4PKHB 2FF6G 4CBUG 4LIZA 1TMWA 2FGHA 5IVUA 1YAGG 1WNJA 5KYWA 5L6WC 1NMDG 1HQZ1 3A5LS 5KYWB 1PD0A 2VILA 3Q2BA 2FF3A 4Z94G 1KCQA 3FFNA 1ESVS 4CBWG 2KVKA 3EH2A 1M4JA 3CI5G 4KEFA 1CNUA 5KYYA 1UDMA 2FH3A 4BEX1 2NUTA 5KYYB 1F7SA 3A5MS 2NUTB 1X67A 2FH2A 1NM1G 5FAEA 1M2VA 1SVRA 1WM4A 2XF1A 1CFYA 1DEJS 2MV2A 1RGIG 1AK7A 1M2VB 3CJCG
chains in the Genus database with same CATH superfamily
2D8BA 3CJBG 1TVJA 2FH1A 1T3YA 3DAWB 3EGXA 2MP4A 4KEEA 3EGXB 1C0FS 5KYXA 2LLFA 3FG7A 5A1MA 1COFA 5KYXB 2NUPA 1T2LA 1T44G 2NUPB 1JHWA 1V6FA 5DD2A 4CBXG 2W0IA 1VKKA 1C0GS 3DA7A 1YVNG 2LXXA 2VACA 1M2OA 3FG6A 5HVKD 1H1VG 2VIKA 3EG9A 3EGDA 3EG9B 3EH1A 3EGDB 1PD1A 1Q8GA 2LJ8A 2MOTA 3FFKA 2QTVA 1WFSA 1NPHA 1MDUA 3L50A 1EQYS 2HD7A 1SVYA 4KEDA 5KYNA 4PKIG 3TU5B 1VFQA 1AK6A 1P8ZG 1J72A 4S10C 5FAFA 3A5NS 1PCXA 1QPVA 1Q8XA 1D0NA 2L72A 3EFOA 1T3XA 3EFOB 5HVKB 2I2QA 1AHQA 4PKGG 3A5OS 3CIPG 2XFAA 5KYUA 1NLVG 4JD2H 5KYUB 2FH4A 1SVQA 1D4XG 1P8XA 4PKHB 2FF6G 4CBUG 4LIZA 1TMWA 2FGHA 5IVUA 1YAGG 1WNJA 5KYWA 5L6WC 1NMDG 1HQZ1 3A5LS 5KYWB 1PD0A 2VILA 3Q2BA 2FF3A 4Z94G 1KCQA 3FFNA 1ESVS 4CBWG 2KVKA 3EH2A 1M4JA 3CI5G 4KEFA 1CNUA 5KYYA 1UDMA 2FH3A 4BEX1 2NUTA 5KYYB 1F7SA 3A5MS 2NUTB 1X67A 2FH2A 1NM1G 5FAEA 1M2VA 1SVRA 1WM4A 2XF1A 1CFYA 1DEJS 2MV2A 1RGIG 1AK7A 1M2VB 3CJCG
chains in the Genus database with same CATH topology
2D8BA 3CJBG 1TVJA 2FH1A 1T3YA 3DAWB 3EGXA 2MP4A 4KEEA 3EGXB 1C0FS 5KYXA 2LLFA 3FG7A 5A1MA 1COFA 5KYXB 2NUPA 1T2LA 1T44G 2NUPB 1JHWA 1V6FA 5DD2A 4CBXG 2W0IA 1VKKA 1C0GS 3DA7A 1YVNG 2LXXA 2VACA 1M2OA 3FG6A 5HVKD 1H1VG 2VIKA 3EG9A 3EGDA 3EG9B 3EH1A 3EGDB 1PD1A 1Q8GA 2LJ8A 2MOTA 3FFKA 2QTVA 1WFSA 1NPHA 1MDUA 3L50A 1EQYS 2HD7A 1SVYA 4KEDA 5KYNA 4PKIG 3TU5B 1VFQA 1AK6A 1P8ZG 1J72A 4S10C 5FAFA 3A5NS 1PCXA 1QPVA 1Q8XA 1D0NA 2L72A 3EFOA 1T3XA 3EFOB 5HVKB 2I2QA 1AHQA 4PKGG 3A5OS 3CIPG 2XFAA 5KYUA 1NLVG 4JD2H 5KYUB 2FH4A 1SVQA 1D4XG 1P8XA 4PKHB 2FF6G 4CBUG 4LIZA 1TMWA 2FGHA 5IVUA 1YAGG 1WNJA 5KYWA 5L6WC 1NMDG 1HQZ1 3A5LS 5KYWB 1PD0A 2VILA 3Q2BA 2FF3A 4Z94G 1KCQA 3FFNA 1ESVS 4CBWG 2KVKA 3EH2A 1M4JA 3CI5G 4KEFA 1CNUA 5KYYA 1UDMA 2FH3A 4BEX1 2NUTA 5KYYB 1F7SA 3A5MS 2NUTB 1X67A 2FH2A 1NM1G 5FAEA 1M2VA 1SVRA 1WM4A 2XF1A 1CFYA 1DEJS 2MV2A 1RGIG 1AK7A 1M2VB 3CJCG
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2D8B A;  3CJB G;  1TVJ A;  2FH1 A;  1T3Y A;  3DAW B;  3EGX A;  2MP4 A;  4KEE A;  3EGX B;  1C0F S;  5KYX A;  2LLF A;  3FG7 A;  5A1M A;  1COF A;  5KYX B;  2NUP A;  1T2L A;  1T44 G;  2NUP B;  1JHW A;  1V6F A;  5DD2 A;  4CBX G;  2W0I A;  1VKK A;  1C0G S;  1YVN G;  2LXX A;  2VAC A;  1M2O A;  3FG6 A;  5HVK D;  1H1V G;  2VIK A;  3EG9 A;  3EGD A;  3EG9 B;  3EH1 A;  3EGD B;  1PD1 A;  1Q8G A;  2LJ8 A;  2MOT A;  3FFK A;  2QTV A;  1WFS A;  1NPH A;  1MDU A;  3L50 A;  1EQY S;  2HD7 A;  1SVY A;  4KED A;  5KYN A;  4PKI G;  3TU5 B;  1VFQ A;  1AK6 A;  1P8Z G;  1J72 A;  4S10 C;  5FAF A;  3A5N S;  1PCX A;  1QPV A;  1Q8X A;  1D0N A;  2L72 A;  3EFO A;  1T3X A;  3EFO B;  5HVK B;  2I2Q A;  1AHQ A;  4PKG G;  3A5O S;  3CIP G;  2XFA A;  5KYU A;  1NLV G;  4JD2 H;  5KYU B;  2FH4 A;  1SVQ A;  1D4X G;  1P8X A;  4PKH B;  2FF6 G;  4CBU G;  4LIZ A;  1TMW A;  2FGH A;  5IVU A;  1YAG G;  1WNJ A;  5KYW A;  5L6W C;  1NMD G;  1HQZ 1;  3A5L S;  5KYW B;  1PD0 A;  2VIL A;  3Q2B A;  2FF3 A;  4Z94 G;  1KCQ A;  3FFN A;  1ESV S;  4CBW G;  2KVK A;  3EH2 A;  1M4J A;  3CI5 G;  4KEF A;  1CNU A;  5KYY A;  1UDM A;  2FH3 A;  4BEX 1;  2NUT A;  5KYY B;  1F7S A;  3A5M S;  2NUT B;  1X67 A;  2FH2 A;  1NM1 G;  5FAE A;  1M2V A;  1SVR A;  1WM4 A;  2XF1 A;  1CFY A;  1DEJ S;  2MV2 A;  1RGI G;  1AK7 A;  1M2V B;  3CJC G; 
#chains in the Genus database with same CATH topology
 2D8B A;  3CJB G;  1TVJ A;  2FH1 A;  1T3Y A;  3DAW B;  3EGX A;  2MP4 A;  4KEE A;  3EGX B;  1C0F S;  5KYX A;  2LLF A;  3FG7 A;  5A1M A;  1COF A;  5KYX B;  2NUP A;  1T2L A;  1T44 G;  2NUP B;  1JHW A;  1V6F A;  5DD2 A;  4CBX G;  2W0I A;  1VKK A;  1C0G S;  3DA7 A;  1YVN G;  2LXX A;  2VAC A;  1M2O A;  3FG6 A;  5HVK D;  1H1V G;  2VIK A;  3EG9 A;  3EGD A;  3EG9 B;  3EH1 A;  3EGD B;  1PD1 A;  1Q8G A;  2LJ8 A;  2MOT A;  3FFK A;  2QTV A;  1WFS A;  1NPH A;  1MDU A;  3L50 A;  1EQY S;  2HD7 A;  1SVY A;  4KED A;  5KYN A;  4PKI G;  3TU5 B;  1VFQ A;  1AK6 A;  1P8Z G;  1J72 A;  4S10 C;  5FAF A;  3A5N S;  1PCX A;  1QPV A;  1Q8X A;  1D0N A;  2L72 A;  3EFO A;  1T3X A;  3EFO B;  5HVK B;  2I2Q A;  1AHQ A;  4PKG G;  3A5O S;  3CIP G;  2XFA A;  5KYU A;  1NLV G;  4JD2 H;  5KYU B;  2FH4 A;  1SVQ A;  1D4X G;  1P8X A;  4PKH B;  2FF6 G;  4CBU G;  4LIZ A;  1TMW A;  2FGH A;  5IVU A;  1YAG G;  1WNJ A;  5KYW A;  5L6W C;  1NMD G;  1HQZ 1;  3A5L S;  5KYW B;  1PD0 A;  2VIL A;  3Q2B A;  2FF3 A;  4Z94 G;  1KCQ A;  3FFN A;  1ESV S;  4CBW G;  2KVK A;  3EH2 A;  1M4J A;  3CI5 G;  4KEF A;  1CNU A;  5KYY A;  1UDM A;  2FH3 A;  4BEX 1;  2NUT A;  5KYY B;  1F7S A;  3A5M S;  2NUT B;  1X67 A;  2FH2 A;  1NM1 G;  5FAE A;  1M2V A;  1SVR A;  1WM4 A;  2XF1 A;  1CFY A;  1DEJ S;  2MV2 A;  1RGI G;  1AK7 A;  1M2V B;  3CJC G; 
#chains in the Genus database with same CATH homology
 2D8B A;  3CJB G;  1TVJ A;  2FH1 A;  1T3Y A;  3DAW B;  3EGX A;  2MP4 A;  4KEE A;  3EGX B;  1C0F S;  5KYX A;  2LLF A;  3FG7 A;  5A1M A;  1COF A;  5KYX B;  2NUP A;  1T2L A;  1T44 G;  2NUP B;  1JHW A;  1V6F A;  5DD2 A;  4CBX G;  2W0I A;  1VKK A;  1C0G S;  3DA7 A;  1YVN G;  2LXX A;  2VAC A;  1M2O A;  3FG6 A;  5HVK D;  1H1V G;  2VIK A;  3EG9 A;  3EGD A;  3EG9 B;  3EH1 A;  3EGD B;  1PD1 A;  1Q8G A;  2LJ8 A;  2MOT A;  3FFK A;  2QTV A;  1WFS A;  1NPH A;  1MDU A;  3L50 A;  1EQY S;  2HD7 A;  1SVY A;  4KED A;  5KYN A;  4PKI G;  3TU5 B;  1VFQ A;  1AK6 A;  1P8Z G;  1J72 A;  4S10 C;  5FAF A;  3A5N S;  1PCX A;  1QPV A;  1Q8X A;  1D0N A;  2L72 A;  3EFO A;  1T3X A;  3EFO B;  5HVK B;  2I2Q A;  1AHQ A;  4PKG G;  3A5O S;  3CIP G;  2XFA A;  5KYU A;  1NLV G;  4JD2 H;  5KYU B;  2FH4 A;  1SVQ A;  1D4X G;  1P8X A;  4PKH B;  2FF6 G;  4CBU G;  4LIZ A;  1TMW A;  2FGH A;  5IVU A;  1YAG G;  1WNJ A;  5KYW A;  5L6W C;  1NMD G;  1HQZ 1;  3A5L S;  5KYW B;  1PD0 A;  2VIL A;  3Q2B A;  2FF3 A;  4Z94 G;  1KCQ A;  3FFN A;  1ESV S;  4CBW G;  2KVK A;  3EH2 A;  1M4J A;  3CI5 G;  4KEF A;  1CNU A;  5KYY A;  1UDM A;  2FH3 A;  4BEX 1;  2NUT A;  5KYY B;  1F7S A;  3A5M S;  2NUT B;  1X67 A;  2FH2 A;  1NM1 G;  5FAE A;  1M2V A;  1SVR A;  1WM4 A;  2XF1 A;  1CFY A;  1DEJ S;  2MV2 A;  1RGI G;  1AK7 A;  1M2V B;  3CJC G; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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