4JD2 | Genus

Total Genus 34

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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	34
sequence length	138
structure length	138
Chain Sequence	DSLVVCEVDPELKETLRKFRFRKETNNAAIIMKVDKDRQMVVLEDELQNISPEELKLELPERQPRFVVYSYKYVHDDGRVSYPLCFIFSSPVGCKPEQQMMYAGSKNRLVQTAELTKVFEIRTTDDLTETWLKEKLAF

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	Structural basis for regulation of Arp2/3 complex by GMF. pubmed doi rcsb
molecule keywords	Actin-related protein 3
molecule tags	Structural protein
total genus	34
structure length	138
sequence length	138
ec nomenclature
pdb deposition date	2013-02-22

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
H	PF00241	Cofilin_ADF	Cofilin/tropomyosin-type actin-binding protein

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.40.20.10	Alpha Beta	3-Layer(aba) Sandwich	Severin	Severin	4jd2H00

5KYNA 4CBWG 3A5NS 3EG9A 5KYUA 2MOTA 4PKGG 2VILA 2L72A 2KVKA 3Q2BA 2FH2A 3A5LS 2XF1A 3TU5B 1NPHA 3EGXA 4PKIG 2I2QA 5KYXA 2NUPA 1KCQA 1M2OA 3FG7A 2W0IA 1P8XA 5KYYA 2QTVA 1PCXA 2LLFA 5L6WC 2LJ8A 2FF6G 4S10C 1CNUA 1SVYA 2VACA 1QPVA 1RGIG 2VIKA 1COFA 2MP4A 2NUTA 3CJCG 3EH1A 3FFKA 5KYYB 1TMWA 2FH1A 1UDMA 1Q8GA 1X67A 3CIPG 3CJBG 2D8BA 1D0NA 1T3XA 2FF3A 5KYWA 3EG9B 5KYUB 1PD0A 3EGDA 3EH2A 5DD2A 2HD7A 1NLVG 3EGXB 3FG6A 1NMDG 5HVKD 5KYXB 2NUPB 4JD2H 1V6FA 3EFOA 1F7SA 1HQZ1 4BEX1 1TVJA 1T2LA 1D4XG 2LXXA 3DAWB 3L50A 2MV2A 5FAFA 5IVUA 2NUTB 1EQYS 1DEJS 2FGHA 1M2VA 1SVRA 4KEDA 4CBXG 2FH4A 1C0GS 1NM1G 1WM4A 1CFYA 1T3YA 5KYWB 3EGDB 1SVQA 5HVKB 1AK6A 4PKHB 1Q8XA 1YAGG 3CI5G 1M4JA 1PD1A 4Z94G 4KEEA 1AK7A 1YVNG 1H1VG 1WFSA 3A5MS 5FAEA 3FFNA 1VKKA 1VFQA 5A1MA 1MDUA 3EFOB 2FH3A 3A5OS 1AHQA 4CBUG 1JHWA 2XFAA 1J72A 4KEFA 1C0FS 1P8ZG 1T44G 1WNJA 1ESVS 1M2VB 4LIZA
chains in the Genus database with same CATH superfamily

5KYNA 4CBWG 3A5NS 3EG9A 5KYUA 2MOTA 4PKGG 2VILA 2L72A 2KVKA 3Q2BA 2FH2A 3A5LS 2XF1A 3TU5B 1NPHA 3EGXA 4PKIG 2I2QA 5KYXA 2NUPA 1KCQA 1M2OA 3FG7A 2W0IA 1P8XA 5KYYA 2QTVA 1PCXA 2LLFA 5L6WC 2LJ8A 2FF6G 4S10C 1CNUA 1SVYA 2VACA 1QPVA 1RGIG 2VIKA 1COFA 2MP4A 2NUTA 3CJCG 3EH1A 3FFKA 5KYYB 1TMWA 2FH1A 1UDMA 1Q8GA 1X67A 3CIPG 3CJBG 2D8BA 1D0NA 1T3XA 2FF3A 5KYWA 3EG9B 5KYUB 1PD0A 3EGDA 3EH2A 5DD2A 2HD7A 1NLVG 3EGXB 3FG6A 1NMDG 5HVKD 5KYXB 2NUPB 4JD2H 1V6FA 3EFOA 1F7SA 1HQZ1 4BEX1 1TVJA 1T2LA 1D4XG 2LXXA 3DAWB 3L50A 2MV2A 5FAFA 5IVUA 2NUTB 1EQYS 1DEJS 2FGHA 1M2VA 1SVRA 4KEDA 4CBXG 2FH4A 1C0GS 3DA7A 1NM1G 1WM4A 1CFYA 1T3YA 5KYWB 3EGDB 1SVQA 5HVKB 1AK6A 4PKHB 1Q8XA 1YAGG 3CI5G 1M4JA 1PD1A 4Z94G 4KEEA 1AK7A 1YVNG 1H1VG 1WFSA 3A5MS 5FAEA 3FFNA 1VKKA 1VFQA 5A1MA 1MDUA 3EFOB 2FH3A 3A5OS 1AHQA 4CBUG 1JHWA 2XFAA 1J72A 4KEFA 1C0FS 1P8ZG 1T44G 1WNJA 1ESVS 1M2VB 4LIZA
chains in the Genus database with same CATH topology

5KYNA 4CBWG 3A5NS 3EG9A 5KYUA 2MOTA 4PKGG 2VILA 2L72A 2KVKA 3Q2BA 2FH2A 3A5LS 2XF1A 3TU5B 1NPHA 3EGXA 4PKIG 2I2QA 5KYXA 2NUPA 1KCQA 1M2OA 3FG7A 2W0IA 1P8XA 5KYYA 2QTVA 1PCXA 2LLFA 5L6WC 2LJ8A 2FF6G 4S10C 1CNUA 1SVYA 2VACA 1QPVA 1RGIG 2VIKA 1COFA 2MP4A 2NUTA 3CJCG 3EH1A 3FFKA 5KYYB 1TMWA 2FH1A 1UDMA 1Q8GA 1X67A 3CIPG 3CJBG 2D8BA 1D0NA 1T3XA 2FF3A 5KYWA 3EG9B 5KYUB 1PD0A 3EGDA 3EH2A 5DD2A 2HD7A 1NLVG 3EGXB 3FG6A 1NMDG 5HVKD 5KYXB 2NUPB 4JD2H 1V6FA 3EFOA 1F7SA 1HQZ1 4BEX1 1TVJA 1T2LA 1D4XG 2LXXA 3DAWB 3L50A 2MV2A 5FAFA 5IVUA 2NUTB 1EQYS 1DEJS 2FGHA 1M2VA 1SVRA 4KEDA 4CBXG 2FH4A 1C0GS 3DA7A 1NM1G 1WM4A 1CFYA 1T3YA 5KYWB 3EGDB 1SVQA 5HVKB 1AK6A 4PKHB 1Q8XA 1YAGG 3CI5G 1M4JA 1PD1A 4Z94G 4KEEA 1AK7A 1YVNG 1H1VG 1WFSA 3A5MS 5FAEA 3FFNA 1VKKA 1VFQA 5A1MA 1MDUA 3EFOB 2FH3A 3A5OS 1AHQA 4CBUG 1JHWA 2XFAA 1J72A 4KEFA 1C0FS 1P8ZG 1T44G 1WNJA 1ESVS 1M2VB 4LIZA
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 5KYN A;  4CBW G;  3A5N S;  3EG9 A;  5KYU A;  2MOT A;  4PKG G;  2VIL A;  2L72 A;  2KVK A;  3Q2B A;  2FH2 A;  3A5L S;  2XF1 A;  3TU5 B;  1NPH A;  3EGX A;  4PKI G;  2I2Q A;  5KYX A;  2NUP A;  1KCQ A;  1M2O A;  3FG7 A;  2W0I A;  1P8X A;  5KYY A;  2QTV A;  1PCX A;  2LLF A;  5L6W C;  2LJ8 A;  2FF6 G;  4S10 C;  1CNU A;  1SVY A;  2VAC A;  1QPV A;  1RGI G;  2VIK A;  1COF A;  2MP4 A;  2NUT A;  3CJC G;  3EH1 A;  3FFK A;  5KYY B;  1TMW A;  2FH1 A;  1UDM A;  1Q8G A;  1X67 A;  3CIP G;  3CJB G;  2D8B A;  1D0N A;  1T3X A;  2FF3 A;  5KYW A;  3EG9 B;  5KYU B;  1PD0 A;  3EGD A;  3EH2 A;  5DD2 A;  2HD7 A;  1NLV G;  3EGX B;  3FG6 A;  1NMD G;  5HVK D;  5KYX B;  2NUP B;  4JD2 H;  1V6F A;  3EFO A;  1F7S A;  1HQZ 1;  4BEX 1;  1TVJ A;  1T2L A;  1D4X G;  2LXX A;  3DAW B;  3L50 A;  2MV2 A;  5FAF A;  5IVU A;  2NUT B;  1EQY S;  1DEJ S;  2FGH A;  1M2V A;  1SVR A;  4KED A;  4CBX G;  2FH4 A;  1C0G S;  1NM1 G;  1WM4 A;  1CFY A;  1T3Y A;  5KYW B;  3EGD B;  1SVQ A;  5HVK B;  1AK6 A;  4PKH B;  1Q8X A;  1YAG G;  3CI5 G;  1M4J A;  1PD1 A;  4Z94 G;  4KEE A;  1AK7 A;  1YVN G;  1H1V G;  1WFS A;  3A5M S;  5FAE A;  3FFN A;  1VKK A;  1VFQ A;  5A1M A;  1MDU A;  3EFO B;  2FH3 A;  3A5O S;  1AHQ A;  4CBU G;  1JHW A;  2XFA A;  1J72 A;  4KEF A;  1C0F S;  1P8Z G;  1T44 G;  1WNJ A;  1ESV S;  1M2V B;  4LIZ A; 
#chains in the Genus database with same CATH topology
 5KYN A;  4CBW G;  3A5N S;  3EG9 A;  5KYU A;  2MOT A;  4PKG G;  2VIL A;  2L72 A;  2KVK A;  3Q2B A;  2FH2 A;  3A5L S;  2XF1 A;  3TU5 B;  1NPH A;  3EGX A;  4PKI G;  2I2Q A;  5KYX A;  2NUP A;  1KCQ A;  1M2O A;  3FG7 A;  2W0I A;  1P8X A;  5KYY A;  2QTV A;  1PCX A;  2LLF A;  5L6W C;  2LJ8 A;  2FF6 G;  4S10 C;  1CNU A;  1SVY A;  2VAC A;  1QPV A;  1RGI G;  2VIK A;  1COF A;  2MP4 A;  2NUT A;  3CJC G;  3EH1 A;  3FFK A;  5KYY B;  1TMW A;  2FH1 A;  1UDM A;  1Q8G A;  1X67 A;  3CIP G;  3CJB G;  2D8B A;  1D0N A;  1T3X A;  2FF3 A;  5KYW A;  3EG9 B;  5KYU B;  1PD0 A;  3EGD A;  3EH2 A;  5DD2 A;  2HD7 A;  1NLV G;  3EGX B;  3FG6 A;  1NMD G;  5HVK D;  5KYX B;  2NUP B;  4JD2 H;  1V6F A;  3EFO A;  1F7S A;  1HQZ 1;  4BEX 1;  1TVJ A;  1T2L A;  1D4X G;  2LXX A;  3DAW B;  3L50 A;  2MV2 A;  5FAF A;  5IVU A;  2NUT B;  1EQY S;  1DEJ S;  2FGH A;  1M2V A;  1SVR A;  4KED A;  4CBX G;  2FH4 A;  1C0G S;  3DA7 A;  1NM1 G;  1WM4 A;  1CFY A;  1T3Y A;  5KYW B;  3EGD B;  1SVQ A;  5HVK B;  1AK6 A;  4PKH B;  1Q8X A;  1YAG G;  3CI5 G;  1M4J A;  1PD1 A;  4Z94 G;  4KEE A;  1AK7 A;  1YVN G;  1H1V G;  1WFS A;  3A5M S;  5FAE A;  3FFN A;  1VKK A;  1VFQ A;  5A1M A;  1MDU A;  3EFO B;  2FH3 A;  3A5O S;  1AHQ A;  4CBU G;  1JHW A;  2XFA A;  1J72 A;  4KEF A;  1C0F S;  1P8Z G;  1T44 G;  1WNJ A;  1ESV S;  1M2V B;  4LIZ A; 
#chains in the Genus database with same CATH homology
 5KYN A;  4CBW G;  3A5N S;  3EG9 A;  5KYU A;  2MOT A;  4PKG G;  2VIL A;  2L72 A;  2KVK A;  3Q2B A;  2FH2 A;  3A5L S;  2XF1 A;  3TU5 B;  1NPH A;  3EGX A;  4PKI G;  2I2Q A;  5KYX A;  2NUP A;  1KCQ A;  1M2O A;  3FG7 A;  2W0I A;  1P8X A;  5KYY A;  2QTV A;  1PCX A;  2LLF A;  5L6W C;  2LJ8 A;  2FF6 G;  4S10 C;  1CNU A;  1SVY A;  2VAC A;  1QPV A;  1RGI G;  2VIK A;  1COF A;  2MP4 A;  2NUT A;  3CJC G;  3EH1 A;  3FFK A;  5KYY B;  1TMW A;  2FH1 A;  1UDM A;  1Q8G A;  1X67 A;  3CIP G;  3CJB G;  2D8B A;  1D0N A;  1T3X A;  2FF3 A;  5KYW A;  3EG9 B;  5KYU B;  1PD0 A;  3EGD A;  3EH2 A;  5DD2 A;  2HD7 A;  1NLV G;  3EGX B;  3FG6 A;  1NMD G;  5HVK D;  5KYX B;  2NUP B;  4JD2 H;  1V6F A;  3EFO A;  1F7S A;  1HQZ 1;  4BEX 1;  1TVJ A;  1T2L A;  1D4X G;  2LXX A;  3DAW B;  3L50 A;  2MV2 A;  5FAF A;  5IVU A;  2NUT B;  1EQY S;  1DEJ S;  2FGH A;  1M2V A;  1SVR A;  4KED A;  4CBX G;  2FH4 A;  1C0G S;  3DA7 A;  1NM1 G;  1WM4 A;  1CFY A;  1T3Y A;  5KYW B;  3EGD B;  1SVQ A;  5HVK B;  1AK6 A;  4PKH B;  1Q8X A;  1YAG G;  3CI5 G;  1M4J A;  1PD1 A;  4Z94 G;  4KEE A;  1AK7 A;  1YVN G;  1H1V G;  1WFS A;  3A5M S;  5FAE A;  3FFN A;  1VKK A;  1VFQ A;  5A1M A;  1MDU A;  3EFO B;  2FH3 A;  3A5O S;  1AHQ A;  4CBU G;  1JHW A;  2XFA A;  1J72 A;  4KEF A;  1C0F S;  1P8Z G;  1T44 G;  1WNJ A;  1ESV S;  1M2V B;  4LIZ A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

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#similar chains, but unknotted
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4JD2H

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations