4KEDA

Crystal structure of cofilin mutant (cof1-157p)
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
134
structure length
131
Chain Sequence
VAVADESLTAFNDLKLGKKYKFILFGLNDAKTEIVVKETSTDPSYDAFLEKLPENDCLYAIYDFEYEINGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSTDVQGTDFSEVSYDSVLEDVSRG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of Cofilin Mutant (cof1-157p)
rcsb
molecule tags Actin binding protein
source organism Saccharomyces cerevisiae
molecule keywords Cofilin
total genus 35
structure length 131
sequence length 134
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-04-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00241 Cofilin_ADF Cofilin/tropomyosin-type actin-binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 4kedA00
1Q8XA 5L6WC 3CI5G 5HVKB 1Q8GA 3A5NS 4KEDA 4PKGG 3Q2BA 2VILA 5KYNA 5KYUA 2FF3A 2I2QA 5DD2A 1X67A 2QTVA 1WNJA 5KYXB 2NUPA 4S10C 3DAWB 4PKHB 1CFYA 3TU5B 3EGXA 1WFSA 2VIKA 3CJCG 1KCQA 1H1VG 4PKIG 5A1MA 4Z94G 2LXXA 2FH4A 2NUTA 1TVJA 2FF6G 1T2LA 4CBUG 1WM4A 2FH1A 2L72A 1VKKA 3EG9B 1EQYS 5KYYB 1DEJS 5KYXA 2MP4A 1YAGG 3CIPG 2XF1A 2LLFA 3A5MS 3CJBG 2FH2A 4BEX1 3EGDB 4KEFA 1P8XA 1M4JA 1AHQA 1AK6A 1MDUA 1NM1G 1SVQA 3A5LS 1M2VB 2HD7A 1VFQA 4KEEA 2MV2A 3EG9A 3EH2A 2VACA 5FAFA 1C0FS 4JD2H 5KYYA 2W0IA 1PCXA 1RGIG 2MOTA 3FG6A 5KYWB 2KVKA 3EGDA 5FAEA 1CNUA 1T3YA 4CBXG 1UDMA 4LIZA 1COFA 1M2VA 3A5OS 5IVUA 1M2OA 1SVRA 2FH3A 1NMDG 1YVNG 1T44G 2NUPB 1JHWA 2LJ8A 3FFNA 5HVKD 3EFOB 1ESVS 1J72A 1HQZ1 3EGXB 1PD0A 1SVYA 1V6FA 4CBWG 1PD1A 2NUTB 1TMWA 1AK7A 2XFAA 3FFKA 1QPVA 1D4XG 3EFOA 1F7SA 3EH1A 2FGHA 1D0NA 5KYUB 3FG7A 1NLVG 3L50A 1NPHA 5KYWA 1T3XA 1P8ZG 1C0GS 2D8BA
chains in the Genus database with same CATH superfamily
1Q8XA 5L6WC 3CI5G 5HVKB 1Q8GA 3A5NS 4KEDA 4PKGG 3Q2BA 2VILA 5KYNA 5KYUA 2FF3A 2I2QA 5DD2A 1X67A 2QTVA 1WNJA 5KYXB 2NUPA 3DA7A 4S10C 3DAWB 4PKHB 1CFYA 3TU5B 3EGXA 1WFSA 2VIKA 3CJCG 1KCQA 1H1VG 4PKIG 5A1MA 4Z94G 2LXXA 2FH4A 2NUTA 1TVJA 2FF6G 1T2LA 4CBUG 1WM4A 2FH1A 2L72A 1VKKA 3EG9B 1EQYS 5KYYB 1DEJS 5KYXA 2MP4A 1YAGG 3CIPG 2XF1A 2LLFA 3A5MS 3CJBG 2FH2A 4BEX1 3EGDB 4KEFA 1P8XA 1M4JA 1AHQA 1AK6A 1MDUA 1NM1G 1SVQA 3A5LS 1M2VB 2HD7A 1VFQA 4KEEA 2MV2A 3EG9A 3EH2A 2VACA 5FAFA 1C0FS 4JD2H 5KYYA 2W0IA 1PCXA 1RGIG 2MOTA 3FG6A 5KYWB 2KVKA 3EGDA 5FAEA 1CNUA 1T3YA 4CBXG 1UDMA 4LIZA 1COFA 1M2VA 3A5OS 5IVUA 1M2OA 1SVRA 2FH3A 1NMDG 1YVNG 1T44G 2NUPB 1JHWA 2LJ8A 3FFNA 5HVKD 3EFOB 1ESVS 1J72A 1HQZ1 3EGXB 1PD0A 1SVYA 1V6FA 4CBWG 1PD1A 2NUTB 1TMWA 1AK7A 2XFAA 3FFKA 1QPVA 1D4XG 3EFOA 1F7SA 3EH1A 2FGHA 1D0NA 5KYUB 3FG7A 1NLVG 3L50A 1NPHA 5KYWA 1T3XA 1P8ZG 1C0GS 2D8BA
chains in the Genus database with same CATH topology
1Q8XA 5L6WC 3CI5G 5HVKB 1Q8GA 3A5NS 4KEDA 4PKGG 3Q2BA 2VILA 5KYNA 5KYUA 2FF3A 2I2QA 5DD2A 1X67A 2QTVA 1WNJA 5KYXB 2NUPA 3DA7A 4S10C 3DAWB 4PKHB 1CFYA 3TU5B 3EGXA 1WFSA 2VIKA 3CJCG 1KCQA 1H1VG 4PKIG 5A1MA 4Z94G 2LXXA 2FH4A 2NUTA 1TVJA 2FF6G 1T2LA 4CBUG 1WM4A 2FH1A 2L72A 1VKKA 3EG9B 1EQYS 5KYYB 1DEJS 5KYXA 2MP4A 1YAGG 3CIPG 2XF1A 2LLFA 3A5MS 3CJBG 2FH2A 4BEX1 3EGDB 4KEFA 1P8XA 1M4JA 1AHQA 1AK6A 1MDUA 1NM1G 1SVQA 3A5LS 1M2VB 2HD7A 1VFQA 4KEEA 2MV2A 3EG9A 3EH2A 2VACA 5FAFA 1C0FS 4JD2H 5KYYA 2W0IA 1PCXA 1RGIG 2MOTA 3FG6A 5KYWB 2KVKA 3EGDA 5FAEA 1CNUA 1T3YA 4CBXG 1UDMA 4LIZA 1COFA 1M2VA 3A5OS 5IVUA 1M2OA 1SVRA 2FH3A 1NMDG 1YVNG 1T44G 2NUPB 1JHWA 2LJ8A 3FFNA 5HVKD 3EFOB 1ESVS 1J72A 1HQZ1 3EGXB 1PD0A 1SVYA 1V6FA 4CBWG 1PD1A 2NUTB 1TMWA 1AK7A 2XFAA 3FFKA 1QPVA 1D4XG 3EFOA 1F7SA 3EH1A 2FGHA 1D0NA 5KYUB 3FG7A 1NLVG 3L50A 1NPHA 5KYWA 1T3XA 1P8ZG 1C0GS 2D8BA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1Q8X A;  5L6W C;  3CI5 G;  5HVK B;  1Q8G A;  3A5N S;  4KED A;  4PKG G;  3Q2B A;  2VIL A;  5KYN A;  5KYU A;  2FF3 A;  2I2Q A;  5DD2 A;  1X67 A;  2QTV A;  1WNJ A;  5KYX B;  2NUP A;  4S10 C;  3DAW B;  4PKH B;  1CFY A;  3TU5 B;  3EGX A;  1WFS A;  2VIK A;  3CJC G;  1KCQ A;  1H1V G;  4PKI G;  5A1M A;  4Z94 G;  2LXX A;  2FH4 A;  2NUT A;  1TVJ A;  2FF6 G;  1T2L A;  4CBU G;  1WM4 A;  2FH1 A;  2L72 A;  1VKK A;  3EG9 B;  1EQY S;  5KYY B;  1DEJ S;  5KYX A;  2MP4 A;  1YAG G;  3CIP G;  2XF1 A;  2LLF A;  3A5M S;  3CJB G;  2FH2 A;  4BEX 1;  3EGD B;  4KEF A;  1P8X A;  1M4J A;  1AHQ A;  1AK6 A;  1MDU A;  1NM1 G;  1SVQ A;  3A5L S;  1M2V B;  2HD7 A;  1VFQ A;  4KEE A;  2MV2 A;  3EG9 A;  3EH2 A;  2VAC A;  5FAF A;  1C0F S;  4JD2 H;  5KYY A;  2W0I A;  1PCX A;  1RGI G;  2MOT A;  3FG6 A;  5KYW B;  2KVK A;  3EGD A;  5FAE A;  1CNU A;  1T3Y A;  4CBX G;  1UDM A;  4LIZ A;  1COF A;  1M2V A;  3A5O S;  5IVU A;  1M2O A;  1SVR A;  2FH3 A;  1NMD G;  1YVN G;  1T44 G;  2NUP B;  1JHW A;  2LJ8 A;  3FFN A;  5HVK D;  3EFO B;  1ESV S;  1J72 A;  1HQZ 1;  3EGX B;  1PD0 A;  1SVY A;  1V6F A;  4CBW G;  1PD1 A;  2NUT B;  1TMW A;  1AK7 A;  2XFA A;  3FFK A;  1QPV A;  1D4X G;  3EFO A;  1F7S A;  3EH1 A;  2FGH A;  1D0N A;  5KYU B;  3FG7 A;  1NLV G;  3L50 A;  1NPH A;  5KYW A;  1T3X A;  1P8Z G;  1C0G S;  2D8B A; 
#chains in the Genus database with same CATH topology
 1Q8X A;  5L6W C;  3CI5 G;  5HVK B;  1Q8G A;  3A5N S;  4KED A;  4PKG G;  3Q2B A;  2VIL A;  5KYN A;  5KYU A;  2FF3 A;  2I2Q A;  5DD2 A;  1X67 A;  2QTV A;  1WNJ A;  5KYX B;  2NUP A;  3DA7 A;  4S10 C;  3DAW B;  4PKH B;  1CFY A;  3TU5 B;  3EGX A;  1WFS A;  2VIK A;  3CJC G;  1KCQ A;  1H1V G;  4PKI G;  5A1M A;  4Z94 G;  2LXX A;  2FH4 A;  2NUT A;  1TVJ A;  2FF6 G;  1T2L A;  4CBU G;  1WM4 A;  2FH1 A;  2L72 A;  1VKK A;  3EG9 B;  1EQY S;  5KYY B;  1DEJ S;  5KYX A;  2MP4 A;  1YAG G;  3CIP G;  2XF1 A;  2LLF A;  3A5M S;  3CJB G;  2FH2 A;  4BEX 1;  3EGD B;  4KEF A;  1P8X A;  1M4J A;  1AHQ A;  1AK6 A;  1MDU A;  1NM1 G;  1SVQ A;  3A5L S;  1M2V B;  2HD7 A;  1VFQ A;  4KEE A;  2MV2 A;  3EG9 A;  3EH2 A;  2VAC A;  5FAF A;  1C0F S;  4JD2 H;  5KYY A;  2W0I A;  1PCX A;  1RGI G;  2MOT A;  3FG6 A;  5KYW B;  2KVK A;  3EGD A;  5FAE A;  1CNU A;  1T3Y A;  4CBX G;  1UDM A;  4LIZ A;  1COF A;  1M2V A;  3A5O S;  5IVU A;  1M2O A;  1SVR A;  2FH3 A;  1NMD G;  1YVN G;  1T44 G;  2NUP B;  1JHW A;  2LJ8 A;  3FFN A;  5HVK D;  3EFO B;  1ESV S;  1J72 A;  1HQZ 1;  3EGX B;  1PD0 A;  1SVY A;  1V6F A;  4CBW G;  1PD1 A;  2NUT B;  1TMW A;  1AK7 A;  2XFA A;  3FFK A;  1QPV A;  1D4X G;  3EFO A;  1F7S A;  3EH1 A;  2FGH A;  1D0N A;  5KYU B;  3FG7 A;  1NLV G;  3L50 A;  1NPH A;  5KYW A;  1T3X A;  1P8Z G;  1C0G S;  2D8B A; 
#chains in the Genus database with same CATH homology
 1Q8X A;  5L6W C;  3CI5 G;  5HVK B;  1Q8G A;  3A5N S;  4KED A;  4PKG G;  3Q2B A;  2VIL A;  5KYN A;  5KYU A;  2FF3 A;  2I2Q A;  5DD2 A;  1X67 A;  2QTV A;  1WNJ A;  5KYX B;  2NUP A;  3DA7 A;  4S10 C;  3DAW B;  4PKH B;  1CFY A;  3TU5 B;  3EGX A;  1WFS A;  2VIK A;  3CJC G;  1KCQ A;  1H1V G;  4PKI G;  5A1M A;  4Z94 G;  2LXX A;  2FH4 A;  2NUT A;  1TVJ A;  2FF6 G;  1T2L A;  4CBU G;  1WM4 A;  2FH1 A;  2L72 A;  1VKK A;  3EG9 B;  1EQY S;  5KYY B;  1DEJ S;  5KYX A;  2MP4 A;  1YAG G;  3CIP G;  2XF1 A;  2LLF A;  3A5M S;  3CJB G;  2FH2 A;  4BEX 1;  3EGD B;  4KEF A;  1P8X A;  1M4J A;  1AHQ A;  1AK6 A;  1MDU A;  1NM1 G;  1SVQ A;  3A5L S;  1M2V B;  2HD7 A;  1VFQ A;  4KEE A;  2MV2 A;  3EG9 A;  3EH2 A;  2VAC A;  5FAF A;  1C0F S;  4JD2 H;  5KYY A;  2W0I A;  1PCX A;  1RGI G;  2MOT A;  3FG6 A;  5KYW B;  2KVK A;  3EGD A;  5FAE A;  1CNU A;  1T3Y A;  4CBX G;  1UDM A;  4LIZ A;  1COF A;  1M2V A;  3A5O S;  5IVU A;  1M2O A;  1SVR A;  2FH3 A;  1NMD G;  1YVN G;  1T44 G;  2NUP B;  1JHW A;  2LJ8 A;  3FFN A;  5HVK D;  3EFO B;  1ESV S;  1J72 A;  1HQZ 1;  3EGX B;  1PD0 A;  1SVY A;  1V6F A;  4CBW G;  1PD1 A;  2NUT B;  1TMW A;  1AK7 A;  2XFA A;  3FFK A;  1QPV A;  1D4X G;  3EFO A;  1F7S A;  3EH1 A;  2FGH A;  1D0N A;  5KYU B;  3FG7 A;  1NLV G;  3L50 A;  1NPH A;  5KYW A;  1T3X A;  1P8Z G;  1C0G S;  2D8B A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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