4KEDA

Crystal structure of cofilin mutant (cof1-157p)
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
134
structure length
131
Chain Sequence
VAVADESLTAFNDLKLGKKYKFILFGLNDAKTEIVVKETSTDPSYDAFLEKLPENDCLYAIYDFEYEINGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSTDVQGTDFSEVSYDSVLEDVSRG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of Cofilin Mutant (cof1-157p)
rcsb
molecule tags Actin binding protein
source organism Saccharomyces cerevisiae
molecule keywords Cofilin
total genus 35
structure length 131
sequence length 134
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-04-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00241 Cofilin_ADF Cofilin/tropomyosin-type actin-binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 4kedA00
1P8XA 2W0IA 5KYUB 3A5MS 1WNJA 1AK7A 4KEEA 2VIKA 1V6FA 3CI5G 4PKGG 5KYXB 3A5NS 2FH3A 2VILA 3EH2A 2XF1A 1PD0A 4CBXG 5KYUA 1AK6A 1WM4A 3CJBG 3FFNA 4PKIG 3TU5B 1SVQA 1SVRA 1T2LA 3A5LS 2MP4A 1NLVG 2FH4A 1TVJA 4KEDA 1P8ZG 2NUTB 3EH1A 1UDMA 3L50A 3DAWB 2L72A 2NUPA 1QPVA 4LIZA 2D8BA 2XFAA 5KYYB 5DD2A 1VKKA 1M2OA 4BEX1 2MV2A 1AHQA 4PKHB 3EGXB 1D4XG 2QTVA 1PD1A 2FF3A 1YAGG 5KYNA 1EQYS 5FAEA 2FGHA 1JHWA 5FAFA 1HQZ1 1T3YA 2I2QA 5KYXA 1CNUA 1C0FS 1M4JA 2FH2A 2VACA 1SVYA 3EGXA 1H1VG 1Q8GA 1DEJS 1M2VB 3A5OS 1TMWA 5A1MA 1X67A 1D0NA 4Z94G 2NUTA 1RGIG 1F7SA 2LLFA 1KCQA 5KYWB 1M2VA 2LXXA 3EFOB 4S10C 2HD7A 5L6WC 3CJCG 4CBUG 5KYYA 3EG9B 5IVUA 5HVKD 3EGDB 5KYWA 5HVKB 3EFOA 1YVNG 1Q8XA 1NMDG 1NM1G 2KVKA 2FF6G 1T3XA 3EG9A 3CIPG 1MDUA 3FG7A 1CFYA 3EGDA 1VFQA 2LJ8A 3FG6A 1T44G 4KEFA 2FH1A 1PCXA 2NUPB 1ESVS 1NPHA 2MOTA 4CBWG 1C0GS 1J72A 1WFSA 1COFA 3Q2BA 3FFKA 4JD2H
chains in the Genus database with same CATH superfamily
1P8XA 2W0IA 5KYUB 3A5MS 1WNJA 1AK7A 4KEEA 2VIKA 1V6FA 3CI5G 4PKGG 5KYXB 3A5NS 2FH3A 2VILA 3EH2A 2XF1A 1PD0A 4CBXG 5KYUA 1AK6A 1WM4A 3CJBG 3FFNA 4PKIG 3TU5B 1SVQA 1SVRA 1T2LA 3A5LS 2MP4A 1NLVG 2FH4A 1TVJA 4KEDA 1P8ZG 2NUTB 3EH1A 1UDMA 3L50A 3DAWB 2L72A 3DA7A 2NUPA 1QPVA 4LIZA 2D8BA 2XFAA 5KYYB 5DD2A 1VKKA 1M2OA 4BEX1 2MV2A 1AHQA 4PKHB 3EGXB 1D4XG 2QTVA 1PD1A 2FF3A 1YAGG 5KYNA 1EQYS 5FAEA 2FGHA 1JHWA 5FAFA 1HQZ1 1T3YA 2I2QA 5KYXA 1CNUA 1C0FS 1M4JA 2FH2A 2VACA 1SVYA 3EGXA 1H1VG 1Q8GA 1DEJS 1M2VB 3A5OS 1TMWA 5A1MA 1X67A 1D0NA 4Z94G 2NUTA 1RGIG 1F7SA 2LLFA 1KCQA 5KYWB 1M2VA 2LXXA 3EFOB 4S10C 2HD7A 5L6WC 3CJCG 4CBUG 5KYYA 3EG9B 5IVUA 5HVKD 3EGDB 5KYWA 5HVKB 3EFOA 1YVNG 1Q8XA 1NMDG 1NM1G 2KVKA 2FF6G 1T3XA 3EG9A 3CIPG 1MDUA 3FG7A 1CFYA 3EGDA 1VFQA 2LJ8A 3FG6A 1T44G 4KEFA 2FH1A 1PCXA 2NUPB 1ESVS 1NPHA 2MOTA 4CBWG 1C0GS 1J72A 1WFSA 1COFA 3Q2BA 3FFKA 4JD2H
chains in the Genus database with same CATH topology
1P8XA 2W0IA 5KYUB 3A5MS 1WNJA 1AK7A 4KEEA 2VIKA 1V6FA 3CI5G 4PKGG 5KYXB 3A5NS 2FH3A 2VILA 3EH2A 2XF1A 1PD0A 4CBXG 5KYUA 1AK6A 1WM4A 3CJBG 3FFNA 4PKIG 3TU5B 1SVQA 1SVRA 1T2LA 3A5LS 2MP4A 1NLVG 2FH4A 1TVJA 4KEDA 1P8ZG 2NUTB 3EH1A 1UDMA 3L50A 3DAWB 2L72A 3DA7A 2NUPA 1QPVA 4LIZA 2D8BA 2XFAA 5KYYB 5DD2A 1VKKA 1M2OA 4BEX1 2MV2A 1AHQA 4PKHB 3EGXB 1D4XG 2QTVA 1PD1A 2FF3A 1YAGG 5KYNA 1EQYS 5FAEA 2FGHA 1JHWA 5FAFA 1HQZ1 1T3YA 2I2QA 5KYXA 1CNUA 1C0FS 1M4JA 2FH2A 2VACA 1SVYA 3EGXA 1H1VG 1Q8GA 1DEJS 1M2VB 3A5OS 1TMWA 5A1MA 1X67A 1D0NA 4Z94G 2NUTA 1RGIG 1F7SA 2LLFA 1KCQA 5KYWB 1M2VA 2LXXA 3EFOB 4S10C 2HD7A 5L6WC 3CJCG 4CBUG 5KYYA 3EG9B 5IVUA 5HVKD 3EGDB 5KYWA 5HVKB 3EFOA 1YVNG 1Q8XA 1NMDG 1NM1G 2KVKA 2FF6G 1T3XA 3EG9A 3CIPG 1MDUA 3FG7A 1CFYA 3EGDA 1VFQA 2LJ8A 3FG6A 1T44G 4KEFA 2FH1A 1PCXA 2NUPB 1ESVS 1NPHA 2MOTA 4CBWG 1C0GS 1J72A 1WFSA 1COFA 3Q2BA 3FFKA 4JD2H
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1P8X A;  2W0I A;  5KYU B;  3A5M S;  1WNJ A;  1AK7 A;  4KEE A;  2VIK A;  1V6F A;  3CI5 G;  4PKG G;  5KYX B;  3A5N S;  2FH3 A;  2VIL A;  3EH2 A;  2XF1 A;  1PD0 A;  4CBX G;  5KYU A;  1AK6 A;  1WM4 A;  3CJB G;  3FFN A;  4PKI G;  3TU5 B;  1SVQ A;  1SVR A;  1T2L A;  3A5L S;  2MP4 A;  1NLV G;  2FH4 A;  1TVJ A;  4KED A;  1P8Z G;  2NUT B;  3EH1 A;  1UDM A;  3L50 A;  3DAW B;  2L72 A;  2NUP A;  1QPV A;  4LIZ A;  2D8B A;  2XFA A;  5KYY B;  5DD2 A;  1VKK A;  1M2O A;  4BEX 1;  2MV2 A;  1AHQ A;  4PKH B;  3EGX B;  1D4X G;  2QTV A;  1PD1 A;  2FF3 A;  1YAG G;  5KYN A;  1EQY S;  5FAE A;  2FGH A;  1JHW A;  5FAF A;  1HQZ 1;  1T3Y A;  2I2Q A;  5KYX A;  1CNU A;  1C0F S;  1M4J A;  2FH2 A;  2VAC A;  1SVY A;  3EGX A;  1H1V G;  1Q8G A;  1DEJ S;  1M2V B;  3A5O S;  1TMW A;  5A1M A;  1X67 A;  1D0N A;  4Z94 G;  2NUT A;  1RGI G;  1F7S A;  2LLF A;  1KCQ A;  5KYW B;  1M2V A;  2LXX A;  3EFO B;  4S10 C;  2HD7 A;  5L6W C;  3CJC G;  4CBU G;  5KYY A;  3EG9 B;  5IVU A;  5HVK D;  3EGD B;  5KYW A;  5HVK B;  3EFO A;  1YVN G;  1Q8X A;  1NMD G;  1NM1 G;  2KVK A;  2FF6 G;  1T3X A;  3EG9 A;  3CIP G;  1MDU A;  3FG7 A;  1CFY A;  3EGD A;  1VFQ A;  2LJ8 A;  3FG6 A;  1T44 G;  4KEF A;  2FH1 A;  1PCX A;  2NUP B;  1ESV S;  1NPH A;  2MOT A;  4CBW G;  1C0G S;  1J72 A;  1WFS A;  1COF A;  3Q2B A;  3FFK A;  4JD2 H; 
#chains in the Genus database with same CATH topology
 1P8X A;  2W0I A;  5KYU B;  3A5M S;  1WNJ A;  1AK7 A;  4KEE A;  2VIK A;  1V6F A;  3CI5 G;  4PKG G;  5KYX B;  3A5N S;  2FH3 A;  2VIL A;  3EH2 A;  2XF1 A;  1PD0 A;  4CBX G;  5KYU A;  1AK6 A;  1WM4 A;  3CJB G;  3FFN A;  4PKI G;  3TU5 B;  1SVQ A;  1SVR A;  1T2L A;  3A5L S;  2MP4 A;  1NLV G;  2FH4 A;  1TVJ A;  4KED A;  1P8Z G;  2NUT B;  3EH1 A;  1UDM A;  3L50 A;  3DAW B;  2L72 A;  3DA7 A;  2NUP A;  1QPV A;  4LIZ A;  2D8B A;  2XFA A;  5KYY B;  5DD2 A;  1VKK A;  1M2O A;  4BEX 1;  2MV2 A;  1AHQ A;  4PKH B;  3EGX B;  1D4X G;  2QTV A;  1PD1 A;  2FF3 A;  1YAG G;  5KYN A;  1EQY S;  5FAE A;  2FGH A;  1JHW A;  5FAF A;  1HQZ 1;  1T3Y A;  2I2Q A;  5KYX A;  1CNU A;  1C0F S;  1M4J A;  2FH2 A;  2VAC A;  1SVY A;  3EGX A;  1H1V G;  1Q8G A;  1DEJ S;  1M2V B;  3A5O S;  1TMW A;  5A1M A;  1X67 A;  1D0N A;  4Z94 G;  2NUT A;  1RGI G;  1F7S A;  2LLF A;  1KCQ A;  5KYW B;  1M2V A;  2LXX A;  3EFO B;  4S10 C;  2HD7 A;  5L6W C;  3CJC G;  4CBU G;  5KYY A;  3EG9 B;  5IVU A;  5HVK D;  3EGD B;  5KYW A;  5HVK B;  3EFO A;  1YVN G;  1Q8X A;  1NMD G;  1NM1 G;  2KVK A;  2FF6 G;  1T3X A;  3EG9 A;  3CIP G;  1MDU A;  3FG7 A;  1CFY A;  3EGD A;  1VFQ A;  2LJ8 A;  3FG6 A;  1T44 G;  4KEF A;  2FH1 A;  1PCX A;  2NUP B;  1ESV S;  1NPH A;  2MOT A;  4CBW G;  1C0G S;  1J72 A;  1WFS A;  1COF A;  3Q2B A;  3FFK A;  4JD2 H; 
#chains in the Genus database with same CATH homology
 1P8X A;  2W0I A;  5KYU B;  3A5M S;  1WNJ A;  1AK7 A;  4KEE A;  2VIK A;  1V6F A;  3CI5 G;  4PKG G;  5KYX B;  3A5N S;  2FH3 A;  2VIL A;  3EH2 A;  2XF1 A;  1PD0 A;  4CBX G;  5KYU A;  1AK6 A;  1WM4 A;  3CJB G;  3FFN A;  4PKI G;  3TU5 B;  1SVQ A;  1SVR A;  1T2L A;  3A5L S;  2MP4 A;  1NLV G;  2FH4 A;  1TVJ A;  4KED A;  1P8Z G;  2NUT B;  3EH1 A;  1UDM A;  3L50 A;  3DAW B;  2L72 A;  3DA7 A;  2NUP A;  1QPV A;  4LIZ A;  2D8B A;  2XFA A;  5KYY B;  5DD2 A;  1VKK A;  1M2O A;  4BEX 1;  2MV2 A;  1AHQ A;  4PKH B;  3EGX B;  1D4X G;  2QTV A;  1PD1 A;  2FF3 A;  1YAG G;  5KYN A;  1EQY S;  5FAE A;  2FGH A;  1JHW A;  5FAF A;  1HQZ 1;  1T3Y A;  2I2Q A;  5KYX A;  1CNU A;  1C0F S;  1M4J A;  2FH2 A;  2VAC A;  1SVY A;  3EGX A;  1H1V G;  1Q8G A;  1DEJ S;  1M2V B;  3A5O S;  1TMW A;  5A1M A;  1X67 A;  1D0N A;  4Z94 G;  2NUT A;  1RGI G;  1F7S A;  2LLF A;  1KCQ A;  5KYW B;  1M2V A;  2LXX A;  3EFO B;  4S10 C;  2HD7 A;  5L6W C;  3CJC G;  4CBU G;  5KYY A;  3EG9 B;  5IVU A;  5HVK D;  3EGD B;  5KYW A;  5HVK B;  3EFO A;  1YVN G;  1Q8X A;  1NMD G;  1NM1 G;  2KVK A;  2FF6 G;  1T3X A;  3EG9 A;  3CIP G;  1MDU A;  3FG7 A;  1CFY A;  3EGD A;  1VFQ A;  2LJ8 A;  3FG6 A;  1T44 G;  4KEF A;  2FH1 A;  1PCX A;  2NUP B;  1ESV S;  1NPH A;  2MOT A;  4CBW G;  1C0G S;  1J72 A;  1WFS A;  1COF A;  3Q2B A;  3FFK A;  4JD2 H; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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