4KEEA

Crystal structure of cofilin mutant (cof1-158p)
Total Genus 34
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
34
sequence length
139
structure length
132
Chain Sequence
GSRSGVAVADESLTAFNDLKLGKKYKFILFGLNDAKTEIVVKETSTDPSYDAFLEKLPENDCLYAIYDFEYEESKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSTDVQGTDFSEVSYDSVLERVSRG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of Cofilin Mutant (cof1-158p)
rcsb
molecule tags Actin binding protein
source organism Saccharomyces cerevisiae
molecule keywords Cofilin
total genus 34
structure length 132
sequence length 139
ec nomenclature
pdb deposition date 2013-04-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00241 Cofilin_ADF Cofilin/tropomyosin-type actin-binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 4keeA00
1M2OA 2FGHA 1C0GS 2VACA 5KYXB 4KEDA 2MP4A 4KEEA 4CBWG 1WFSA 2XF1A 5A1MA 4JD2H 5IVUA 3L50A 1COFA 5FAFA 1KCQA 2MOTA 1D4XG 2NUPA 2NUTA 5FAEA 1T3XA 3A5LS 3DAWB 1CFYA 5HVKB 3EG9A 1SVYA 2FH4A 1T44G 1AHQA 3EG9B 4PKGG 1SVRA 1NMDG 1MDUA 3CJBG 4Z94G 5KYNA 2HD7A 1NM1G 4CBUG 5HVKD 1PD0A 4PKIG 3FG7A 2FF6G 1HQZ1 2QTVA 3FG6A 1UDMA 3Q2BA 1M4JA 1D0NA 2VIKA 2VILA 3CIPG 1M2VB 1WM4A 3FFKA 2XFAA 2FH3A 1ESVS 1YVNG 2LLFA 3EFOB 5KYYB 1NLVG 1SVQA 5KYUB 4LIZA 1H1VG 4S10C 1J72A 3CJCG 1QPVA 2MV2A 3TU5B 1AK6A 3A5OS 1PCXA 1Q8GA 1M2VA 4KEFA 5L6WC 1JHWA 2LJ8A 3EGXA 3EFOA 5KYYA 1V6FA 1X67A 1DEJS 3CI5G 5KYUA 1TMWA 5KYWA 2D8BA 3EGXB 5DD2A 1T3YA 2FH2A 1AK7A 1VKKA 1CNUA 1EQYS 3FFNA 5KYWB 3EH1A 1P8ZG 2L72A 4CBXG 3EGDA 1C0FS 1Q8XA 2FH1A 1NPHA 2I2QA 2FF3A 3EGDB 1PD1A 1YAGG 1P8XA 3A5NS 1TVJA 1F7SA 4PKHB 3A5MS 2LXXA 2KVKA 3EH2A 2W0IA 1VFQA 2NUPB 2NUTB 5KYXA 1RGIG 4BEX1 1T2LA 1WNJA
chains in the Genus database with same CATH superfamily
1M2OA 2FGHA 1C0GS 2VACA 5KYXB 4KEDA 2MP4A 4KEEA 4CBWG 1WFSA 2XF1A 5A1MA 4JD2H 5IVUA 3L50A 1COFA 5FAFA 1KCQA 2MOTA 1D4XG 2NUPA 2NUTA 5FAEA 1T3XA 3A5LS 3DAWB 1CFYA 5HVKB 3EG9A 1SVYA 2FH4A 1T44G 1AHQA 3EG9B 4PKGG 1SVRA 1NMDG 1MDUA 3CJBG 4Z94G 5KYNA 2HD7A 1NM1G 4CBUG 5HVKD 1PD0A 4PKIG 3FG7A 2FF6G 1HQZ1 2QTVA 3FG6A 1UDMA 3Q2BA 1M4JA 1D0NA 2VIKA 2VILA 3CIPG 1M2VB 1WM4A 3FFKA 2XFAA 2FH3A 1ESVS 1YVNG 2LLFA 3EFOB 5KYYB 1NLVG 1SVQA 5KYUB 4LIZA 1H1VG 4S10C 1J72A 3CJCG 1QPVA 2MV2A 3TU5B 1AK6A 3A5OS 1PCXA 1Q8GA 1M2VA 4KEFA 5L6WC 1JHWA 2LJ8A 3EGXA 3EFOA 5KYYA 1V6FA 1X67A 1DEJS 3CI5G 5KYUA 1TMWA 5KYWA 2D8BA 3EGXB 5DD2A 1T3YA 2FH2A 1AK7A 1VKKA 1CNUA 1EQYS 3FFNA 5KYWB 3EH1A 1P8ZG 2L72A 4CBXG 3EGDA 1C0FS 1Q8XA 2FH1A 1NPHA 2I2QA 2FF3A 3EGDB 1PD1A 1YAGG 1P8XA 3A5NS 1TVJA 1F7SA 4PKHB 3A5MS 2LXXA 2KVKA 3EH2A 2W0IA 1VFQA 2NUPB 2NUTB 5KYXA 1RGIG 4BEX1 1T2LA 1WNJA 3DA7A
chains in the Genus database with same CATH topology
1M2OA 2FGHA 1C0GS 2VACA 5KYXB 4KEDA 2MP4A 4KEEA 4CBWG 1WFSA 2XF1A 5A1MA 4JD2H 5IVUA 3L50A 1COFA 5FAFA 1KCQA 2MOTA 1D4XG 2NUPA 2NUTA 5FAEA 1T3XA 3A5LS 3DAWB 1CFYA 5HVKB 3EG9A 1SVYA 2FH4A 1T44G 1AHQA 3EG9B 4PKGG 1SVRA 1NMDG 1MDUA 3CJBG 4Z94G 5KYNA 2HD7A 1NM1G 4CBUG 5HVKD 1PD0A 4PKIG 3FG7A 2FF6G 1HQZ1 2QTVA 3FG6A 1UDMA 3Q2BA 1M4JA 1D0NA 2VIKA 2VILA 3CIPG 1M2VB 1WM4A 3FFKA 2XFAA 2FH3A 1ESVS 1YVNG 2LLFA 3EFOB 5KYYB 1NLVG 1SVQA 5KYUB 4LIZA 1H1VG 4S10C 1J72A 3CJCG 1QPVA 2MV2A 3TU5B 1AK6A 3A5OS 1PCXA 1Q8GA 1M2VA 4KEFA 5L6WC 1JHWA 2LJ8A 3EGXA 3EFOA 5KYYA 1V6FA 1X67A 1DEJS 3CI5G 5KYUA 1TMWA 5KYWA 2D8BA 3EGXB 5DD2A 1T3YA 2FH2A 1AK7A 1VKKA 1CNUA 1EQYS 3FFNA 5KYWB 3EH1A 1P8ZG 2L72A 4CBXG 3EGDA 1C0FS 1Q8XA 2FH1A 1NPHA 2I2QA 2FF3A 3EGDB 1PD1A 1YAGG 1P8XA 3A5NS 1TVJA 1F7SA 4PKHB 3A5MS 2LXXA 2KVKA 3EH2A 2W0IA 1VFQA 2NUPB 2NUTB 5KYXA 1RGIG 4BEX1 1T2LA 1WNJA 3DA7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1M2O A;  2FGH A;  1C0G S;  2VAC A;  5KYX B;  4KED A;  2MP4 A;  4KEE A;  4CBW G;  1WFS A;  2XF1 A;  5A1M A;  4JD2 H;  5IVU A;  3L50 A;  1COF A;  5FAF A;  1KCQ A;  2MOT A;  1D4X G;  2NUP A;  2NUT A;  5FAE A;  1T3X A;  3A5L S;  3DAW B;  1CFY A;  5HVK B;  3EG9 A;  1SVY A;  2FH4 A;  1T44 G;  1AHQ A;  3EG9 B;  4PKG G;  1SVR A;  1NMD G;  1MDU A;  3CJB G;  4Z94 G;  5KYN A;  2HD7 A;  1NM1 G;  4CBU G;  5HVK D;  1PD0 A;  4PKI G;  3FG7 A;  2FF6 G;  1HQZ 1;  2QTV A;  3FG6 A;  1UDM A;  3Q2B A;  1M4J A;  1D0N A;  2VIK A;  2VIL A;  3CIP G;  1M2V B;  1WM4 A;  3FFK A;  2XFA A;  2FH3 A;  1ESV S;  1YVN G;  2LLF A;  3EFO B;  5KYY B;  1NLV G;  1SVQ A;  5KYU B;  4LIZ A;  1H1V G;  4S10 C;  1J72 A;  3CJC G;  1QPV A;  2MV2 A;  3TU5 B;  1AK6 A;  3A5O S;  1PCX A;  1Q8G A;  1M2V A;  4KEF A;  5L6W C;  1JHW A;  2LJ8 A;  3EGX A;  3EFO A;  5KYY A;  1V6F A;  1X67 A;  1DEJ S;  3CI5 G;  5KYU A;  1TMW A;  5KYW A;  2D8B A;  3EGX B;  5DD2 A;  1T3Y A;  2FH2 A;  1AK7 A;  1VKK A;  1CNU A;  1EQY S;  3FFN A;  5KYW B;  3EH1 A;  1P8Z G;  2L72 A;  4CBX G;  3EGD A;  1C0F S;  1Q8X A;  2FH1 A;  1NPH A;  2I2Q A;  2FF3 A;  3EGD B;  1PD1 A;  1YAG G;  1P8X A;  3A5N S;  1TVJ A;  1F7S A;  4PKH B;  3A5M S;  2LXX A;  2KVK A;  3EH2 A;  2W0I A;  1VFQ A;  2NUP B;  2NUT B;  5KYX A;  1RGI G;  4BEX 1;  1T2L A;  1WNJ A; 
#chains in the Genus database with same CATH topology
 1M2O A;  2FGH A;  1C0G S;  2VAC A;  5KYX B;  4KED A;  2MP4 A;  4KEE A;  4CBW G;  1WFS A;  2XF1 A;  5A1M A;  4JD2 H;  5IVU A;  3L50 A;  1COF A;  5FAF A;  1KCQ A;  2MOT A;  1D4X G;  2NUP A;  2NUT A;  5FAE A;  1T3X A;  3A5L S;  3DAW B;  1CFY A;  5HVK B;  3EG9 A;  1SVY A;  2FH4 A;  1T44 G;  1AHQ A;  3EG9 B;  4PKG G;  1SVR A;  1NMD G;  1MDU A;  3CJB G;  4Z94 G;  5KYN A;  2HD7 A;  1NM1 G;  4CBU G;  5HVK D;  1PD0 A;  4PKI G;  3FG7 A;  2FF6 G;  1HQZ 1;  2QTV A;  3FG6 A;  1UDM A;  3Q2B A;  1M4J A;  1D0N A;  2VIK A;  2VIL A;  3CIP G;  1M2V B;  1WM4 A;  3FFK A;  2XFA A;  2FH3 A;  1ESV S;  1YVN G;  2LLF A;  3EFO B;  5KYY B;  1NLV G;  1SVQ A;  5KYU B;  4LIZ A;  1H1V G;  4S10 C;  1J72 A;  3CJC G;  1QPV A;  2MV2 A;  3TU5 B;  1AK6 A;  3A5O S;  1PCX A;  1Q8G A;  1M2V A;  4KEF A;  5L6W C;  1JHW A;  2LJ8 A;  3EGX A;  3EFO A;  5KYY A;  1V6F A;  1X67 A;  1DEJ S;  3CI5 G;  5KYU A;  1TMW A;  5KYW A;  2D8B A;  3EGX B;  5DD2 A;  1T3Y A;  2FH2 A;  1AK7 A;  1VKK A;  1CNU A;  1EQY S;  3FFN A;  5KYW B;  3EH1 A;  1P8Z G;  2L72 A;  4CBX G;  3EGD A;  1C0F S;  1Q8X A;  2FH1 A;  1NPH A;  2I2Q A;  2FF3 A;  3EGD B;  1PD1 A;  1YAG G;  1P8X A;  3A5N S;  1TVJ A;  1F7S A;  4PKH B;  3A5M S;  2LXX A;  2KVK A;  3EH2 A;  2W0I A;  1VFQ A;  2NUP B;  2NUT B;  5KYX A;  1RGI G;  4BEX 1;  1T2L A;  1WNJ A;  3DA7 A; 
#chains in the Genus database with same CATH homology
 1M2O A;  2FGH A;  1C0G S;  2VAC A;  5KYX B;  4KED A;  2MP4 A;  4KEE A;  4CBW G;  1WFS A;  2XF1 A;  5A1M A;  4JD2 H;  5IVU A;  3L50 A;  1COF A;  5FAF A;  1KCQ A;  2MOT A;  1D4X G;  2NUP A;  2NUT A;  5FAE A;  1T3X A;  3A5L S;  3DAW B;  1CFY A;  5HVK B;  3EG9 A;  1SVY A;  2FH4 A;  1T44 G;  1AHQ A;  3EG9 B;  4PKG G;  1SVR A;  1NMD G;  1MDU A;  3CJB G;  4Z94 G;  5KYN A;  2HD7 A;  1NM1 G;  4CBU G;  5HVK D;  1PD0 A;  4PKI G;  3FG7 A;  2FF6 G;  1HQZ 1;  2QTV A;  3FG6 A;  1UDM A;  3Q2B A;  1M4J A;  1D0N A;  2VIK A;  2VIL A;  3CIP G;  1M2V B;  1WM4 A;  3FFK A;  2XFA A;  2FH3 A;  1ESV S;  1YVN G;  2LLF A;  3EFO B;  5KYY B;  1NLV G;  1SVQ A;  5KYU B;  4LIZ A;  1H1V G;  4S10 C;  1J72 A;  3CJC G;  1QPV A;  2MV2 A;  3TU5 B;  1AK6 A;  3A5O S;  1PCX A;  1Q8G A;  1M2V A;  4KEF A;  5L6W C;  1JHW A;  2LJ8 A;  3EGX A;  3EFO A;  5KYY A;  1V6F A;  1X67 A;  1DEJ S;  3CI5 G;  5KYU A;  1TMW A;  5KYW A;  2D8B A;  3EGX B;  5DD2 A;  1T3Y A;  2FH2 A;  1AK7 A;  1VKK A;  1CNU A;  1EQY S;  3FFN A;  5KYW B;  3EH1 A;  1P8Z G;  2L72 A;  4CBX G;  3EGD A;  1C0F S;  1Q8X A;  2FH1 A;  1NPH A;  2I2Q A;  2FF3 A;  3EGD B;  1PD1 A;  1YAG G;  1P8X A;  3A5N S;  1TVJ A;  1F7S A;  4PKH B;  3A5M S;  2LXX A;  2KVK A;  3EH2 A;  2W0I A;  1VFQ A;  2NUP B;  2NUT B;  5KYX A;  1RGI G;  4BEX 1;  1T2L A;  1WNJ A;  3DA7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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