1FZBC

Crystal structure of crosslinked fragment d
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
309
structure length
309
Chain Sequence
KMLEEIMKYEASILTHDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHDITGKDCQDIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGWWMNKCHAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKIIPFNRLTIGE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of fragment D from human fibrinogen and its crosslinked counterpart from fibrin.
pubmed doi rcsb
molecule tags Blood coagulation
molecule keywords FIBRINOGEN
total genus 86
structure length 309
sequence length 309
chains with identical sequence F
ec nomenclature
pdb deposition date 1997-08-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 1fzbC01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 1fzbC02
2J64A 1Z3UA 1M1JB 1LWUB 4JZCA 3E1IB 4ZFGA 3BVHB 1FZEB 2GY7A 1N86C 2J0HA 2J2PA 2Z4EC 3H32C 1LT9B 2J61A 2XNXC 1RE3C 4R9JA 2H43B 2OYIC 2HLOB 4JYOX 2Q9IB 1RF0C 2OYHC 2JHHC 1FZFB 1FICA 2J5ZA 2J60A 2HODB 2FFDC 1RF1B 2J3GA 3GHGC 1N73C 1FIBA 2HPCB 4M7HA 1FZAB 3HUSB 2FIBA 2JHMF 1FZCC 1RE4B 2J0YA 4NYTA 1FZBB 1FZBC 1FZGC 1LTJC 1FZDA 2J3FD 1M1JC 1LWUC 1FIDA 3E1IC 3BVHC 1FZEC 1N86B 2Z4EB 1JC9A 3H32B 1Z3SA 2WNPF 2XNXB 1RE3B 2J61B 4R9TA 2OYIB 2JHKF 2J1GA 1LT9C 4EPUA 1RF0B 2H43C 2OYHB 2HLOC 1LTJB 2Q9IC 2J0GA 4M7FA 2FFDB 1FZFC 1N73B 2HODC 1RF1C 2J3OA 2HPCC 3FIBA 2J3FA 1FZAC 3HUSC 2JHIF 1FZCB 2D39A 1FZGB 2J3UA 1RE4C 2JHLF
chains in the Genus database with same CATH superfamily
2J64A 1Z3UA 1M1JB 1LWUB 4JZCA 3E1IB 4ZFGA 3BVHB 1FZEB 2GY7A 1N86C 2J0HA 2J2PA 2Z4EC 3H32C 1LT9B 2J61A 2XNXC 1RE3C 4R9JA 2H43B 2OYIC 2HLOB 4JYOX 2Q9IB 1RF0C 2OYHC 2JHHC 1FZFB 1FICA 2J5ZA 2J60A 2HODB 2FFDC 1RF1B 2J3GA 3GHGC 1N73C 1FIBA 2HPCB 4M7HA 1FZAB 3HUSB 2FIBA 2JHMF 1FZCC 1RE4B 2J0YA 4NYTA 1FZBB 1FZBC 1FZGC 1LTJC 1FZDA 2J3FD 1M1JC 1LWUC 1FIDA 3E1IC 3BVHC 1FZEC 1N86B 2Z4EB 1JC9A 3H32B 1Z3SA 2WNPF 2XNXB 1RE3B 2J61B 4R9TA 2OYIB 2JHKF 2J1GA 1LT9C 4EPUA 1RF0B 2H43C 2OYHB 2HLOC 1LTJB 2Q9IC 2J0GA 4M7FA 2FFDB 1FZFC 3GHGB 1N73B 2HODC 1RF1C 2J3OA 2HPCC 3FIBA 2J3FA 1FZAC 3HUSC 2JHIF 1FZCB 2D39A 1FZGB 2J3UA 1RE4C 2JHLF
chains in the Genus database with same CATH topology
2J64A 1Z3UA 1M1JB 1LWUB 4JZCA 3E1IB 4ZFGA 3BVHB 1FZEB 2GY7A 1N86C 2J0HA 2J2PA 2Z4EC 3H32C 1LT9B 2J61A 2XNXC 1RE3C 4R9JA 2H43B 2OYIC 2HLOB 4JYOX 2Q9IB 1RF0C 2OYHC 2JHHC 1FZFB 1FICA 2J5ZA 2J60A 2HODB 2FFDC 1RF1B 2J3GA 3GHGC 1N73C 1FIBA 2HPCB 4M7HA 1FZAB 3HUSB 2FIBA 2JHMF 1FZCC 1RE4B 2J0YA 4NYTA 1FZBB 1FZBC 1FZGC 1LTJC 1FZDA 2J3FD 1M1JC 1LWUC 1FIDA 3E1IC 3BVHC 1FZEC 1N86B 2Z4EB 1JC9A 3H32B 1Z3SA 2WNPF 2XNXB 1RE3B 2J61B 4R9TA 2OYIB 2JHKF 2J1GA 1LT9C 4EPUA 1RF0B 2H43C 2OYHB 2HLOC 1LTJB 2Q9IC 2J0GA 4M7FA 2FFDB 1FZFC 1N73B 2HODC 1RF1C 2J3OA 2HPCC 3FIBA 2J3FA 1FZAC 3HUSC 2JHIF 1FZCB 2D39A 1FZGB 2J3UA 1RE4C 2JHLF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2J64 A;  1Z3U A;  1M1J B;  1LWU B;  4JZC A;  3E1I B;  4ZFG A;  3BVH B;  1FZE B;  2GY7 A;  1N86 C;  2J0H A;  2J2P A;  2Z4E C;  3H32 C;  1LT9 B;  2J61 A;  2XNX C;  1RE3 C;  4R9J A;  2H43 B;  2OYI C;  2HLO B;  4JYO X;  2Q9I B;  1RF0 C;  2OYH C;  2JHH C;  1FZF B;  1FIC A;  2J5Z A;  2J60 A;  2HOD B;  2FFD C;  1RF1 B;  2J3G A;  3GHG C;  1N73 C;  1FIB A;  2HPC B;  4M7H A;  1FZA B;  3HUS B;  2FIB A;  2JHM F;  1FZC C;  1RE4 B;  2J0Y A;  4NYT A;  1FZB B;  1FZB C;  1FZG C;  1LTJ C;  1FZD A;  2J3F D;  1M1J C;  1LWU C;  1FID A;  3E1I C;  3BVH C;  1FZE C;  1N86 B;  2Z4E B;  1JC9 A;  3H32 B;  1Z3S A;  2WNP F;  2XNX B;  1RE3 B;  2J61 B;  4R9T A;  2OYI B;  2JHK F;  2J1G A;  1LT9 C;  4EPU A;  1RF0 B;  2H43 C;  2OYH B;  2HLO C;  1LTJ B;  2Q9I C;  2J0G A;  4M7F A;  2FFD B;  1FZF C;  1N73 B;  2HOD C;  1RF1 C;  2J3O A;  2HPC C;  3FIB A;  2J3F A;  1FZA C;  3HUS C;  2JHI F;  1FZC B;  2D39 A;  1FZG B;  2J3U A;  1RE4 C;  2JHL F; 
#chains in the Genus database with same CATH topology
 2J64 A;  1Z3U A;  1M1J B;  1LWU B;  4JZC A;  3E1I B;  4ZFG A;  3BVH B;  1FZE B;  2GY7 A;  1N86 C;  2J0H A;  2J2P A;  2Z4E C;  3H32 C;  1LT9 B;  2J61 A;  2XNX C;  1RE3 C;  4R9J A;  2H43 B;  2OYI C;  2HLO B;  4JYO X;  2Q9I B;  1RF0 C;  2OYH C;  2JHH C;  1FZF B;  1FIC A;  2J5Z A;  2J60 A;  2HOD B;  2FFD C;  1RF1 B;  2J3G A;  3GHG C;  1N73 C;  1FIB A;  2HPC B;  4M7H A;  1FZA B;  3HUS B;  2FIB A;  2JHM F;  1FZC C;  1RE4 B;  2J0Y A;  4NYT A;  1FZB B;  1FZB C;  1FZG C;  1LTJ C;  1FZD A;  2J3F D;  1M1J C;  1LWU C;  1FID A;  3E1I C;  3BVH C;  1FZE C;  1N86 B;  2Z4E B;  1JC9 A;  3H32 B;  1Z3S A;  2WNP F;  2XNX B;  1RE3 B;  2J61 B;  4R9T A;  2OYI B;  2JHK F;  2J1G A;  1LT9 C;  4EPU A;  1RF0 B;  2H43 C;  2OYH B;  2HLO C;  1LTJ B;  2Q9I C;  2J0G A;  4M7F A;  2FFD B;  1FZF C;  3GHG B;  1N73 B;  2HOD C;  1RF1 C;  2J3O A;  2HPC C;  3FIB A;  2J3F A;  1FZA C;  3HUS C;  2JHI F;  1FZC B;  2D39 A;  1FZG B;  2J3U A;  1RE4 C;  2JHL F; 
#chains in the Genus database with same CATH homology
 2J64 A;  1Z3U A;  1M1J B;  1LWU B;  4JZC A;  3E1I B;  4ZFG A;  3BVH B;  1FZE B;  2GY7 A;  1N86 C;  2J0H A;  2J2P A;  2Z4E C;  3H32 C;  1LT9 B;  2J61 A;  2XNX C;  1RE3 C;  4R9J A;  2H43 B;  2OYI C;  2HLO B;  4JYO X;  2Q9I B;  1RF0 C;  2OYH C;  2JHH C;  1FZF B;  1FIC A;  2J5Z A;  2J60 A;  2HOD B;  2FFD C;  1RF1 B;  2J3G A;  3GHG C;  1N73 C;  1FIB A;  2HPC B;  4M7H A;  1FZA B;  3HUS B;  2FIB A;  2JHM F;  1FZC C;  1RE4 B;  2J0Y A;  4NYT A;  1FZB B;  1FZB C;  1FZG C;  1LTJ C;  1FZD A;  2J3F D;  1M1J C;  1LWU C;  1FID A;  3E1I C;  3BVH C;  1FZE C;  1N86 B;  2Z4E B;  1JC9 A;  3H32 B;  1Z3S A;  2WNP F;  2XNX B;  1RE3 B;  2J61 B;  4R9T A;  2OYI B;  2JHK F;  2J1G A;  1LT9 C;  4EPU A;  1RF0 B;  2H43 C;  2OYH B;  2HLO C;  1LTJ B;  2Q9I C;  2J0G A;  4M7F A;  2FFD B;  1FZF C;  1N73 B;  2HOD C;  1RF1 C;  2J3O A;  2HPC C;  3FIB A;  2J3F A;  1FZA C;  3HUS C;  2JHI F;  1FZC B;  2D39 A;  1FZG B;  2J3U A;  1RE4 C;  2JHL F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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