3BVHB

Crystal structure of recombinant gammad364a fibrinogen fragment d with the peptide ligand gly-pro-arg-pro-amide
Total Genus 93
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
93
sequence length
298
structure length
298
Chain Sequence
IPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKMSMKIRPFF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Polymerization-defective fibrinogen variant gammaD364A binds knob "A" peptide mimic.
pubmed doi rcsb
molecule keywords Fibrinogen alpha chain
molecule tags Blood clotting
source organism Homo sapiens
total genus 93
structure length 298
sequence length 298
chains with identical sequence E
ec nomenclature
pdb deposition date 2008-01-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 3bvhB01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 3bvhB02
1FZBB 1FIDA 2HPCC 1FZGB 2GY7A 1FZEC 2D39A 2HLOC 2J60A 1FZDA 1N73C 2J3OA 2J3FA 2HODB 2H43C 1LT9C 4R9JA 2FIBA 2J61A 1FIBA 1FZBC 2J2PA 1FZCC 1LWUB 2J1GA 2XNXB 3E1IC 1FZFB 2HODC 2Q9IC 2J64A 1RE3C 1M1JB 1RE4B 3BVHB 3H32B 3HUSB 4M7HA 1LWUC 2JHKF 1Z3SA 2OYHB 1RF1B 4M7FA 1FZGC 2J0YA 2XNXC 1FZAB 1FICA 1FZFC 2FFDB 1N86B 2JHIF 1RE4C 1Z3UA 2J61B 2J0HA 3H32C 3HUSC 2JHMF 2HPCB 1FZEB 2J3FD 2Z4EB 2JHLF 1RF1C 2J5ZA 1LTJB 4EPUA 1FZAC 2FFDC 4JZCA 1N86C 1RF0B 2JHHC 3GHGC 2WNPF 1FZCB 2OYIB 1M1JC 2J3UA 2Z4EC 4JYOX 3BVHC 1LTJC 1JC9A 4NYTA 3E1IB 2J0GA 2OYHC 2HLOB 2Q9IB 1RF0C 1RE3B 1N73B 3FIBA 4ZFGA 2H43B 2J3GA 1LT9B 2OYIC 4R9TA
chains in the Genus database with same CATH superfamily
1FZBB 1FIDA 2HPCC 1FZGB 2GY7A 1FZEC 2D39A 2HLOC 2J60A 1FZDA 1N73C 2J3OA 2J3FA 2HODB 2H43C 1LT9C 4R9JA 2FIBA 2J61A 1FIBA 1FZBC 2J2PA 1FZCC 1LWUB 2J1GA 3GHGB 2XNXB 3E1IC 1FZFB 2HODC 2Q9IC 2J64A 1RE3C 1M1JB 1RE4B 3BVHB 3H32B 3HUSB 4M7HA 1LWUC 2JHKF 1Z3SA 2OYHB 1RF1B 4M7FA 1FZGC 2J0YA 2XNXC 1FZAB 1FICA 1FZFC 2FFDB 1N86B 2JHIF 1RE4C 1Z3UA 2J61B 2J0HA 3H32C 3HUSC 2JHMF 2HPCB 1FZEB 2J3FD 2Z4EB 2JHLF 1RF1C 2J5ZA 1LTJB 4EPUA 1FZAC 2FFDC 4JZCA 1N86C 1RF0B 2JHHC 3GHGC 2WNPF 1FZCB 2OYIB 1M1JC 2J3UA 2Z4EC 4JYOX 3BVHC 1LTJC 1JC9A 4NYTA 3E1IB 2J0GA 2OYHC 2HLOB 2Q9IB 1RF0C 1RE3B 1N73B 3FIBA 4ZFGA 2H43B 2J3GA 1LT9B 2OYIC 4R9TA
chains in the Genus database with same CATH topology
1FZBB 1FIDA 2HPCC 1FZGB 2GY7A 1FZEC 2D39A 2HLOC 2J60A 1FZDA 1N73C 2J3OA 2J3FA 2HODB 2H43C 1LT9C 4R9JA 2FIBA 2J61A 1FIBA 1FZBC 2J2PA 1FZCC 1LWUB 2J1GA 2XNXB 3E1IC 1FZFB 2HODC 2Q9IC 2J64A 1RE3C 1M1JB 1RE4B 3BVHB 3H32B 3HUSB 4M7HA 1LWUC 2JHKF 1Z3SA 2OYHB 1RF1B 4M7FA 1FZGC 2J0YA 2XNXC 1FZAB 1FICA 1FZFC 2FFDB 1N86B 2JHIF 1RE4C 1Z3UA 2J61B 2J0HA 3H32C 3HUSC 2JHMF 2HPCB 1FZEB 2J3FD 2Z4EB 2JHLF 1RF1C 2J5ZA 1LTJB 4EPUA 1FZAC 2FFDC 4JZCA 1N86C 1RF0B 2JHHC 3GHGC 2WNPF 1FZCB 2OYIB 1M1JC 2J3UA 2Z4EC 4JYOX 3BVHC 1LTJC 1JC9A 4NYTA 3E1IB 2J0GA 2OYHC 2HLOB 2Q9IB 1RF0C 1RE3B 1N73B 3FIBA 4ZFGA 2H43B 2J3GA 1LT9B 2OYIC 4R9TA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FZB B;  1FID A;  2HPC C;  1FZG B;  2GY7 A;  1FZE C;  2D39 A;  2HLO C;  2J60 A;  1FZD A;  1N73 C;  2J3O A;  2J3F A;  2HOD B;  2H43 C;  1LT9 C;  4R9J A;  2FIB A;  2J61 A;  1FIB A;  1FZB C;  2J2P A;  1FZC C;  1LWU B;  2J1G A;  2XNX B;  3E1I C;  1FZF B;  2HOD C;  2Q9I C;  2J64 A;  1RE3 C;  1M1J B;  1RE4 B;  3BVH B;  3H32 B;  3HUS B;  4M7H A;  1LWU C;  2JHK F;  1Z3S A;  2OYH B;  1RF1 B;  4M7F A;  1FZG C;  2J0Y A;  2XNX C;  1FZA B;  1FIC A;  1FZF C;  2FFD B;  1N86 B;  2JHI F;  1RE4 C;  1Z3U A;  2J61 B;  2J0H A;  3H32 C;  3HUS C;  2JHM F;  2HPC B;  1FZE B;  2J3F D;  2Z4E B;  2JHL F;  1RF1 C;  2J5Z A;  1LTJ B;  4EPU A;  1FZA C;  2FFD C;  4JZC A;  1N86 C;  1RF0 B;  2JHH C;  3GHG C;  2WNP F;  1FZC B;  2OYI B;  1M1J C;  2J3U A;  2Z4E C;  4JYO X;  3BVH C;  1LTJ C;  1JC9 A;  4NYT A;  3E1I B;  2J0G A;  2OYH C;  2HLO B;  2Q9I B;  1RF0 C;  1RE3 B;  1N73 B;  3FIB A;  4ZFG A;  2H43 B;  2J3G A;  1LT9 B;  2OYI C;  4R9T A; 
#chains in the Genus database with same CATH topology
 1FZB B;  1FID A;  2HPC C;  1FZG B;  2GY7 A;  1FZE C;  2D39 A;  2HLO C;  2J60 A;  1FZD A;  1N73 C;  2J3O A;  2J3F A;  2HOD B;  2H43 C;  1LT9 C;  4R9J A;  2FIB A;  2J61 A;  1FIB A;  1FZB C;  2J2P A;  1FZC C;  1LWU B;  2J1G A;  3GHG B;  2XNX B;  3E1I C;  1FZF B;  2HOD C;  2Q9I C;  2J64 A;  1RE3 C;  1M1J B;  1RE4 B;  3BVH B;  3H32 B;  3HUS B;  4M7H A;  1LWU C;  2JHK F;  1Z3S A;  2OYH B;  1RF1 B;  4M7F A;  1FZG C;  2J0Y A;  2XNX C;  1FZA B;  1FIC A;  1FZF C;  2FFD B;  1N86 B;  2JHI F;  1RE4 C;  1Z3U A;  2J61 B;  2J0H A;  3H32 C;  3HUS C;  2JHM F;  2HPC B;  1FZE B;  2J3F D;  2Z4E B;  2JHL F;  1RF1 C;  2J5Z A;  1LTJ B;  4EPU A;  1FZA C;  2FFD C;  4JZC A;  1N86 C;  1RF0 B;  2JHH C;  3GHG C;  2WNP F;  1FZC B;  2OYI B;  1M1J C;  2J3U A;  2Z4E C;  4JYO X;  3BVH C;  1LTJ C;  1JC9 A;  4NYT A;  3E1I B;  2J0G A;  2OYH C;  2HLO B;  2Q9I B;  1RF0 C;  1RE3 B;  1N73 B;  3FIB A;  4ZFG A;  2H43 B;  2J3G A;  1LT9 B;  2OYI C;  4R9T A; 
#chains in the Genus database with same CATH homology
 1FZB B;  1FID A;  2HPC C;  1FZG B;  2GY7 A;  1FZE C;  2D39 A;  2HLO C;  2J60 A;  1FZD A;  1N73 C;  2J3O A;  2J3F A;  2HOD B;  2H43 C;  1LT9 C;  4R9J A;  2FIB A;  2J61 A;  1FIB A;  1FZB C;  2J2P A;  1FZC C;  1LWU B;  2J1G A;  2XNX B;  3E1I C;  1FZF B;  2HOD C;  2Q9I C;  2J64 A;  1RE3 C;  1M1J B;  1RE4 B;  3BVH B;  3H32 B;  3HUS B;  4M7H A;  1LWU C;  2JHK F;  1Z3S A;  2OYH B;  1RF1 B;  4M7F A;  1FZG C;  2J0Y A;  2XNX C;  1FZA B;  1FIC A;  1FZF C;  2FFD B;  1N86 B;  2JHI F;  1RE4 C;  1Z3U A;  2J61 B;  2J0H A;  3H32 C;  3HUS C;  2JHM F;  2HPC B;  1FZE B;  2J3F D;  2Z4E B;  2JHL F;  1RF1 C;  2J5Z A;  1LTJ B;  4EPU A;  1FZA C;  2FFD C;  4JZC A;  1N86 C;  1RF0 B;  2JHH C;  3GHG C;  2WNP F;  1FZC B;  2OYI B;  1M1J C;  2J3U A;  2Z4E C;  4JYO X;  3BVH C;  1LTJ C;  1JC9 A;  4NYT A;  3E1I B;  2J0G A;  2OYH C;  2HLO B;  2Q9I B;  1RF0 C;  1RE3 B;  1N73 B;  3FIB A;  4ZFG A;  2H43 B;  2J3G A;  1LT9 B;  2OYI C;  4R9T A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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