1FZEC

Crystal structure of fragment double-d from human fibrin
Total Genus 85
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
85
sequence length
303
structure length
303
Chain Sequence
EIMKYEASILTHDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHDITGKDCQDIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGWWMNKCHAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKIIPFNRLTI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Conformational changes in fragments D and double-D from human fibrin(ogen) upon binding the peptide ligand Gly-His-Arg-Pro-amide.
pubmed doi rcsb
molecule tags Blood coagulation
molecule keywords FIBRINOGEN
total genus 85
structure length 303
sequence length 303
chains with identical sequence F
ec nomenclature
pdb deposition date 1998-12-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 1fzeC01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 1fzeC02
1LTJC 2J3GA 1FZFB 2HODB 2GY7A 1LT9C 1JC9A 2J3FA 4ZFGA 2Q9IC 2J0GA 2J0YA 1FZBC 1N86C 2OYHC 3H32B 1RE4B 3HUSC 2J3FD 2J61B 1RF1B 2OYIC 2Z4EB 2J5ZA 2FIBA 2J64A 2HODC 1LWUB 2HLOB 3FIBA 1FZEC 1Z3SA 4R9TA 1FZGB 2J61A 1M1JC 2JHHC 1FIBA 2XNXB 2JHIF 2FFDB 4M7FA 1RF0C 1FIDA 4EPUA 1RE3B 3BVHB 1FZAC 2J2PA 2D39A 2WNPF 1FZFC 1LWUC 2J1GA 2HLOC 1FZCB 2J3UA 3E1IB 4JYOX 1N86B 1N73B 2OYHB 2HPCB 2J60A 3GHGC 3H32C 3HUSB 2H43B 1RE4C 2JHMF 2FFDC 4NYTA 1RF1C 1RE3C 2Z4EC 1LTJB 1FICA 2JHKF 4R9JA 1Z3UA 1FZCC 1FZEB 1LT9B 3E1IC 4M7HA 2Q9IB 1N73C 1FZBB 2J3OA 2HPCC 2JHLF 1FZDA 1FZGC 1M1JB 2H43C 2J0HA 2XNXC 1RF0B 2OYIB 1FZAB 3BVHC 4JZCA
chains in the Genus database with same CATH superfamily
1LTJC 2J3GA 1FZFB 2HODB 2GY7A 1LT9C 1JC9A 2J3FA 4ZFGA 2Q9IC 2J0GA 2J0YA 1FZBC 1N86C 2OYHC 3H32B 1RE4B 3HUSC 2J3FD 2J61B 1RF1B 2OYIC 2Z4EB 2J5ZA 2FIBA 2J64A 2HODC 1LWUB 2HLOB 3FIBA 1FZEC 1Z3SA 4R9TA 1FZGB 2J61A 3GHGB 1M1JC 2JHHC 1FIBA 2XNXB 2JHIF 2FFDB 4M7FA 1RF0C 1FIDA 4EPUA 1RE3B 3BVHB 1FZAC 2J2PA 2D39A 2WNPF 1FZFC 1LWUC 2J1GA 2HLOC 1FZCB 2J3UA 3E1IB 4JYOX 1N86B 1N73B 2OYHB 2HPCB 2J60A 3GHGC 3H32C 3HUSB 2H43B 1RE4C 2JHMF 2FFDC 4NYTA 1RF1C 1RE3C 2Z4EC 1LTJB 1FICA 2JHKF 4R9JA 1Z3UA 1FZCC 1FZEB 1LT9B 3E1IC 4M7HA 2Q9IB 1N73C 1FZBB 2J3OA 2HPCC 2JHLF 1FZDA 1FZGC 1M1JB 2H43C 2J0HA 2XNXC 1RF0B 2OYIB 1FZAB 3BVHC 4JZCA
chains in the Genus database with same CATH topology
1LTJC 2J3GA 1FZFB 2HODB 2GY7A 1LT9C 1JC9A 2J3FA 4ZFGA 2Q9IC 2J0GA 2J0YA 1FZBC 1N86C 2OYHC 3H32B 1RE4B 3HUSC 2J3FD 2J61B 1RF1B 2OYIC 2Z4EB 2J5ZA 2FIBA 2J64A 2HODC 1LWUB 2HLOB 3FIBA 1FZEC 1Z3SA 4R9TA 1FZGB 2J61A 1M1JC 2JHHC 1FIBA 2XNXB 2JHIF 2FFDB 4M7FA 1RF0C 1FIDA 4EPUA 1RE3B 3BVHB 1FZAC 2J2PA 2D39A 2WNPF 1FZFC 1LWUC 2J1GA 2HLOC 1FZCB 2J3UA 3E1IB 4JYOX 1N86B 1N73B 2OYHB 2HPCB 2J60A 3GHGC 3H32C 3HUSB 2H43B 1RE4C 2JHMF 2FFDC 4NYTA 1RF1C 1RE3C 2Z4EC 1LTJB 1FICA 2JHKF 4R9JA 1Z3UA 1FZCC 1FZEB 1LT9B 3E1IC 4M7HA 2Q9IB 1N73C 1FZBB 2J3OA 2HPCC 2JHLF 1FZDA 1FZGC 1M1JB 2H43C 2J0HA 2XNXC 1RF0B 2OYIB 1FZAB 3BVHC 4JZCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1LTJ C;  2J3G A;  1FZF B;  2HOD B;  2GY7 A;  1LT9 C;  1JC9 A;  2J3F A;  4ZFG A;  2Q9I C;  2J0G A;  2J0Y A;  1FZB C;  1N86 C;  2OYH C;  3H32 B;  1RE4 B;  3HUS C;  2J3F D;  2J61 B;  1RF1 B;  2OYI C;  2Z4E B;  2J5Z A;  2FIB A;  2J64 A;  2HOD C;  1LWU B;  2HLO B;  3FIB A;  1FZE C;  1Z3S A;  4R9T A;  1FZG B;  2J61 A;  1M1J C;  2JHH C;  1FIB A;  2XNX B;  2JHI F;  2FFD B;  4M7F A;  1RF0 C;  1FID A;  4EPU A;  1RE3 B;  3BVH B;  1FZA C;  2J2P A;  2D39 A;  2WNP F;  1FZF C;  1LWU C;  2J1G A;  2HLO C;  1FZC B;  2J3U A;  3E1I B;  4JYO X;  1N86 B;  1N73 B;  2OYH B;  2HPC B;  2J60 A;  3GHG C;  3H32 C;  3HUS B;  2H43 B;  1RE4 C;  2JHM F;  2FFD C;  4NYT A;  1RF1 C;  1RE3 C;  2Z4E C;  1LTJ B;  1FIC A;  2JHK F;  4R9J A;  1Z3U A;  1FZC C;  1FZE B;  1LT9 B;  3E1I C;  4M7H A;  2Q9I B;  1N73 C;  1FZB B;  2J3O A;  2HPC C;  2JHL F;  1FZD A;  1FZG C;  1M1J B;  2H43 C;  2J0H A;  2XNX C;  1RF0 B;  2OYI B;  1FZA B;  3BVH C;  4JZC A; 
#chains in the Genus database with same CATH topology
 1LTJ C;  2J3G A;  1FZF B;  2HOD B;  2GY7 A;  1LT9 C;  1JC9 A;  2J3F A;  4ZFG A;  2Q9I C;  2J0G A;  2J0Y A;  1FZB C;  1N86 C;  2OYH C;  3H32 B;  1RE4 B;  3HUS C;  2J3F D;  2J61 B;  1RF1 B;  2OYI C;  2Z4E B;  2J5Z A;  2FIB A;  2J64 A;  2HOD C;  1LWU B;  2HLO B;  3FIB A;  1FZE C;  1Z3S A;  4R9T A;  1FZG B;  2J61 A;  3GHG B;  1M1J C;  2JHH C;  1FIB A;  2XNX B;  2JHI F;  2FFD B;  4M7F A;  1RF0 C;  1FID A;  4EPU A;  1RE3 B;  3BVH B;  1FZA C;  2J2P A;  2D39 A;  2WNP F;  1FZF C;  1LWU C;  2J1G A;  2HLO C;  1FZC B;  2J3U A;  3E1I B;  4JYO X;  1N86 B;  1N73 B;  2OYH B;  2HPC B;  2J60 A;  3GHG C;  3H32 C;  3HUS B;  2H43 B;  1RE4 C;  2JHM F;  2FFD C;  4NYT A;  1RF1 C;  1RE3 C;  2Z4E C;  1LTJ B;  1FIC A;  2JHK F;  4R9J A;  1Z3U A;  1FZC C;  1FZE B;  1LT9 B;  3E1I C;  4M7H A;  2Q9I B;  1N73 C;  1FZB B;  2J3O A;  2HPC C;  2JHL F;  1FZD A;  1FZG C;  1M1J B;  2H43 C;  2J0H A;  2XNX C;  1RF0 B;  2OYI B;  1FZA B;  3BVH C;  4JZC A; 
#chains in the Genus database with same CATH homology
 1LTJ C;  2J3G A;  1FZF B;  2HOD B;  2GY7 A;  1LT9 C;  1JC9 A;  2J3F A;  4ZFG A;  2Q9I C;  2J0G A;  2J0Y A;  1FZB C;  1N86 C;  2OYH C;  3H32 B;  1RE4 B;  3HUS C;  2J3F D;  2J61 B;  1RF1 B;  2OYI C;  2Z4E B;  2J5Z A;  2FIB A;  2J64 A;  2HOD C;  1LWU B;  2HLO B;  3FIB A;  1FZE C;  1Z3S A;  4R9T A;  1FZG B;  2J61 A;  1M1J C;  2JHH C;  1FIB A;  2XNX B;  2JHI F;  2FFD B;  4M7F A;  1RF0 C;  1FID A;  4EPU A;  1RE3 B;  3BVH B;  1FZA C;  2J2P A;  2D39 A;  2WNP F;  1FZF C;  1LWU C;  2J1G A;  2HLO C;  1FZC B;  2J3U A;  3E1I B;  4JYO X;  1N86 B;  1N73 B;  2OYH B;  2HPC B;  2J60 A;  3GHG C;  3H32 C;  3HUS B;  2H43 B;  1RE4 C;  2JHM F;  2FFD C;  4NYT A;  1RF1 C;  1RE3 C;  2Z4E C;  1LTJ B;  1FIC A;  2JHK F;  4R9J A;  1Z3U A;  1FZC C;  1FZE B;  1LT9 B;  3E1I C;  4M7H A;  2Q9I B;  1N73 C;  1FZB B;  2J3O A;  2HPC C;  2JHL F;  1FZD A;  1FZG C;  1M1J B;  2H43 C;  2J0H A;  2XNX C;  1RF0 B;  2OYI B;  1FZA B;  3BVH C;  4JZC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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