2WNPF

M-ficolin mutant y271f
Total Genus 76
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
76
sequence length
217
structure length
217
Chain Sequence
SCATGPRNCKDLLDRGYFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRRMDGSVDFYRDWAAYKQGFGSQLGEFWLGNDNIHALTAQGSSELRVDLVDFEGNHQFAKYKSFKVADEAEKYKLVLGAFVGGSAGNSLTGHNNNFFSTKDQDNDVSSSNCAEKFQGAWWYADCHASNLNGLYLMGPHESFANGINWSAAKGYKYSYKVSEMKVRPA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Carbohydrate Recognition Properties of Human Ficolins: Glycan Array Screening Reveals the Sialic Acid Binding Specificity of M-Ficolin.
pubmed doi rcsb
molecule tags Immune system
source organism Homo sapiens
molecule keywords FICOLIN-1
total genus 76
structure length 217
sequence length 217
ec nomenclature
pdb deposition date 2009-07-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 2wnpF01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 2wnpF02
1N73C 1FZGC 1FZGB 1FZFB 2OYIB 2OYHB 4R9TA 2J3FD 2H43B 1LT9B 4R9JA 1RF0B 1RF0C 2JHIF 2XNXB 4NYTA 1FZAC 1FZBB 1FZDA 2D39A 3BVHB 1FZEB 4M7FA 4ZFGA 1RE3B 1Z3UA 2J61A 2J3OA 1LWUB 3GHGC 2HODB 1FZFC 2OYIC 2J61B 2OYHC 2H43C 2WNPF 2HPCB 1LT9C 2JHLF 1M1JB 2XNXC 1FZBC 1FZCB 3BVHC 1FZEC 2Z4EB 1RF1B 1RE3C 2HLOB 1LTJB 1RE4B 2J0YA 2Q9IB 1LWUC 2FFDB 2J3UA 2J2PA 2HODC 2FIBA 2JHKF 3FIBA 2J0GA 2J1GA 4JZCA 3H32B 4EPUA 1JC9A 2J64A 2HPCC 2GY7A 4JYOX 2J5ZA 1M1JC 1FZCC 1N86B 2JHMF 3HUSB 2J3FA 2Z4EC 1RF1C 2HLOC 1N73B 4M7HA 1LTJC 1FIBA 1RE4C 1FICA 2Q9IC 2FFDC 2J60A 1FIDA 3H32C 2JHHC 3E1IC 3E1IB 1FZAB 2J3GA 2J0HA 1Z3SA 1N86C 3HUSC
chains in the Genus database with same CATH superfamily
1N73C 3GHGB 1FZGC 1FZGB 1FZFB 2OYIB 2OYHB 4R9TA 2J3FD 2H43B 1LT9B 4R9JA 1RF0B 1RF0C 2JHIF 2XNXB 4NYTA 1FZAC 1FZBB 1FZDA 2D39A 3BVHB 1FZEB 4M7FA 4ZFGA 1RE3B 1Z3UA 2J61A 2J3OA 1LWUB 3GHGC 2HODB 1FZFC 2OYIC 2J61B 2OYHC 2H43C 2WNPF 2HPCB 1LT9C 2JHLF 1M1JB 2XNXC 1FZBC 1FZCB 3BVHC 1FZEC 2Z4EB 1RF1B 1RE3C 2HLOB 1LTJB 1RE4B 2J0YA 2Q9IB 1LWUC 2FFDB 2J3UA 2J2PA 2HODC 2FIBA 2JHKF 3FIBA 2J0GA 2J1GA 4JZCA 3H32B 4EPUA 1JC9A 2J64A 2HPCC 2GY7A 4JYOX 2J5ZA 1M1JC 1FZCC 1N86B 2JHMF 3HUSB 2J3FA 2Z4EC 1RF1C 2HLOC 1N73B 4M7HA 1LTJC 1FIBA 1RE4C 1FICA 2Q9IC 2FFDC 2J60A 1FIDA 3H32C 2JHHC 3E1IC 3E1IB 1FZAB 2J3GA 2J0HA 1Z3SA 1N86C 3HUSC
chains in the Genus database with same CATH topology
1N73C 1FZGC 1FZGB 1FZFB 2OYIB 2OYHB 4R9TA 2J3FD 2H43B 1LT9B 4R9JA 1RF0B 1RF0C 2JHIF 2XNXB 4NYTA 1FZAC 1FZBB 1FZDA 2D39A 3BVHB 1FZEB 4M7FA 4ZFGA 1RE3B 1Z3UA 2J61A 2J3OA 1LWUB 3GHGC 2HODB 1FZFC 2OYIC 2J61B 2OYHC 2H43C 2WNPF 2HPCB 1LT9C 2JHLF 1M1JB 2XNXC 1FZBC 1FZCB 3BVHC 1FZEC 2Z4EB 1RF1B 1RE3C 2HLOB 1LTJB 1RE4B 2J0YA 2Q9IB 1LWUC 2FFDB 2J3UA 2J2PA 2HODC 2FIBA 2JHKF 3FIBA 2J0GA 2J1GA 4JZCA 3H32B 4EPUA 1JC9A 2J64A 2HPCC 2GY7A 4JYOX 2J5ZA 1M1JC 1FZCC 1N86B 2JHMF 3HUSB 2J3FA 2Z4EC 1RF1C 2HLOC 1N73B 4M7HA 1LTJC 1FIBA 1RE4C 1FICA 2Q9IC 2FFDC 2J60A 1FIDA 3H32C 2JHHC 3E1IC 3E1IB 1FZAB 2J3GA 2J0HA 1Z3SA 1N86C 3HUSC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1N73 C;  1FZG C;  1FZG B;  1FZF B;  2OYI B;  2OYH B;  4R9T A;  2J3F D;  2H43 B;  1LT9 B;  4R9J A;  1RF0 B;  1RF0 C;  2JHI F;  2XNX B;  4NYT A;  1FZA C;  1FZB B;  1FZD A;  2D39 A;  3BVH B;  1FZE B;  4M7F A;  4ZFG A;  1RE3 B;  1Z3U A;  2J61 A;  2J3O A;  1LWU B;  3GHG C;  2HOD B;  1FZF C;  2OYI C;  2J61 B;  2OYH C;  2H43 C;  2WNP F;  2HPC B;  1LT9 C;  2JHL F;  1M1J B;  2XNX C;  1FZB C;  1FZC B;  3BVH C;  1FZE C;  2Z4E B;  1RF1 B;  1RE3 C;  2HLO B;  1LTJ B;  1RE4 B;  2J0Y A;  2Q9I B;  1LWU C;  2FFD B;  2J3U A;  2J2P A;  2HOD C;  2FIB A;  2JHK F;  3FIB A;  2J0G A;  2J1G A;  4JZC A;  3H32 B;  4EPU A;  1JC9 A;  2J64 A;  2HPC C;  2GY7 A;  4JYO X;  2J5Z A;  1M1J C;  1FZC C;  1N86 B;  2JHM F;  3HUS B;  2J3F A;  2Z4E C;  1RF1 C;  2HLO C;  1N73 B;  4M7H A;  1LTJ C;  1FIB A;  1RE4 C;  1FIC A;  2Q9I C;  2FFD C;  2J60 A;  1FID A;  3H32 C;  2JHH C;  3E1I C;  3E1I B;  1FZA B;  2J3G A;  2J0H A;  1Z3S A;  1N86 C;  3HUS C; 
#chains in the Genus database with same CATH topology
 1N73 C;  3GHG B;  1FZG C;  1FZG B;  1FZF B;  2OYI B;  2OYH B;  4R9T A;  2J3F D;  2H43 B;  1LT9 B;  4R9J A;  1RF0 B;  1RF0 C;  2JHI F;  2XNX B;  4NYT A;  1FZA C;  1FZB B;  1FZD A;  2D39 A;  3BVH B;  1FZE B;  4M7F A;  4ZFG A;  1RE3 B;  1Z3U A;  2J61 A;  2J3O A;  1LWU B;  3GHG C;  2HOD B;  1FZF C;  2OYI C;  2J61 B;  2OYH C;  2H43 C;  2WNP F;  2HPC B;  1LT9 C;  2JHL F;  1M1J B;  2XNX C;  1FZB C;  1FZC B;  3BVH C;  1FZE C;  2Z4E B;  1RF1 B;  1RE3 C;  2HLO B;  1LTJ B;  1RE4 B;  2J0Y A;  2Q9I B;  1LWU C;  2FFD B;  2J3U A;  2J2P A;  2HOD C;  2FIB A;  2JHK F;  3FIB A;  2J0G A;  2J1G A;  4JZC A;  3H32 B;  4EPU A;  1JC9 A;  2J64 A;  2HPC C;  2GY7 A;  4JYO X;  2J5Z A;  1M1J C;  1FZC C;  1N86 B;  2JHM F;  3HUS B;  2J3F A;  2Z4E C;  1RF1 C;  2HLO C;  1N73 B;  4M7H A;  1LTJ C;  1FIB A;  1RE4 C;  1FIC A;  2Q9I C;  2FFD C;  2J60 A;  1FID A;  3H32 C;  2JHH C;  3E1I C;  3E1I B;  1FZA B;  2J3G A;  2J0H A;  1Z3S A;  1N86 C;  3HUS C; 
#chains in the Genus database with same CATH homology
 1N73 C;  1FZG C;  1FZG B;  1FZF B;  2OYI B;  2OYH B;  4R9T A;  2J3F D;  2H43 B;  1LT9 B;  4R9J A;  1RF0 B;  1RF0 C;  2JHI F;  2XNX B;  4NYT A;  1FZA C;  1FZB B;  1FZD A;  2D39 A;  3BVH B;  1FZE B;  4M7F A;  4ZFG A;  1RE3 B;  1Z3U A;  2J61 A;  2J3O A;  1LWU B;  3GHG C;  2HOD B;  1FZF C;  2OYI C;  2J61 B;  2OYH C;  2H43 C;  2WNP F;  2HPC B;  1LT9 C;  2JHL F;  1M1J B;  2XNX C;  1FZB C;  1FZC B;  3BVH C;  1FZE C;  2Z4E B;  1RF1 B;  1RE3 C;  2HLO B;  1LTJ B;  1RE4 B;  2J0Y A;  2Q9I B;  1LWU C;  2FFD B;  2J3U A;  2J2P A;  2HOD C;  2FIB A;  2JHK F;  3FIB A;  2J0G A;  2J1G A;  4JZC A;  3H32 B;  4EPU A;  1JC9 A;  2J64 A;  2HPC C;  2GY7 A;  4JYO X;  2J5Z A;  1M1J C;  1FZC C;  1N86 B;  2JHM F;  3HUS B;  2J3F A;  2Z4E C;  1RF1 C;  2HLO C;  1N73 B;  4M7H A;  1LTJ C;  1FIB A;  1RE4 C;  1FIC A;  2Q9I C;  2FFD C;  2J60 A;  1FID A;  3H32 C;  2JHH C;  3E1I C;  3E1I B;  1FZA B;  2J3G A;  2J0H A;  1Z3S A;  1N86 C;  3HUS C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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