2JHIF

Structure of globular heads of m-ficolin complexed with n-acetyl-d- galactosamine
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
217
structure length
217
Chain Sequence
SCATGPRNCKDLLDRGHFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRRMDGSVDFYRDWAAYKQGFGSQLGEFWLGNDNIHALTAQGSSELRTDLVDFEGNHQFAKYKSFKVADEAEKYKLVLGAFVGGSAGNSLTGHNNNFFSTKDQDNDVSSSNCAEKFQGAWWYADCHASNLNGLYLMGPHESYANGINWSAAKGYKYSYKVSEMKVRPA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Innate Immune Sensing by M-Ficolin and its Control by a Ph-Dependent Conformational Switch.
pubmed doi rcsb
molecule tags Sugar binding protein
source organism Homo sapiens
molecule keywords FICOLIN-1
total genus 75
structure length 217
sequence length 217
ec nomenclature
pdb deposition date 2007-02-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 2jhiF01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 2jhiF02
1N86C 2JHIF 3GHGC 1N86B 2J61A 3BVHC 2HODC 3BVHB 1FIDA 2J60A 1FZDA 2OYIB 1FZAC 1LWUC 2H43C 4M7HA 1FZAB 2H43B 1RE3B 2OYHC 2GY7A 1FZEC 2OYHB 4JZCA 1FZEB 1RE4C 3E1IC 3H32B 2J61B 2HLOB 3E1IB 1RF1C 1RF1B 4R9JA 2J3FD 1N73C 2J5ZA 1N73B 2J0GA 2OYIC 2J3GA 2J2PA 1RE3C 2J3UA 2JHMF 3FIBA 2FFDC 3H32C 4JYOX 1JC9A 2FFDB 1FIBA 2HLOC 1M1JC 1M1JB 4NYTA 2HPCB 2J64A 2J1GA 2JHKF 2J3OA 2D39A 2JHHC 1LTJC 2Z4EC 2WNPF 1LTJB 2Z4EB 1LT9C 1FZBC 1LT9B 2J0YA 1FZBB 1Z3SA 2J3FA 1FICA 1FZGC 2XNXB 1FZGB 1Z3UA 4ZFGA 2HPCC 3HUSC 2HODB 3HUSB 4M7FA 1FZFC 1RF0C 4EPUA 1FZFB 1RF0B 1LWUB 2J0HA 1FZCC 1FZCB 2Q9IC 2JHLF 2Q9IB 1RE4B 4R9TA 2XNXC 2FIBA
chains in the Genus database with same CATH superfamily
1N86C 2JHIF 3GHGC 1N86B 2J61A 3GHGB 3BVHC 2HODC 3BVHB 1FIDA 2J60A 1FZDA 2OYIB 1FZAC 1LWUC 2H43C 4M7HA 1FZAB 2H43B 1RE3B 2OYHC 2GY7A 1FZEC 2OYHB 4JZCA 1FZEB 1RE4C 3E1IC 3H32B 2J61B 2HLOB 3E1IB 1RF1C 1RF1B 4R9JA 2J3FD 1N73C 2J5ZA 1N73B 2J0GA 2OYIC 2J3GA 2J2PA 1RE3C 2J3UA 2JHMF 3FIBA 2FFDC 3H32C 4JYOX 1JC9A 2FFDB 1FIBA 2HLOC 1M1JC 1M1JB 4NYTA 2HPCB 2J64A 2J1GA 2JHKF 2J3OA 2D39A 2JHHC 1LTJC 2Z4EC 2WNPF 1LTJB 2Z4EB 1LT9C 1FZBC 1LT9B 2J0YA 1FZBB 1Z3SA 2J3FA 1FICA 1FZGC 2XNXB 1FZGB 1Z3UA 4ZFGA 2HPCC 3HUSC 2HODB 3HUSB 4M7FA 1FZFC 1RF0C 4EPUA 1FZFB 1RF0B 1LWUB 2J0HA 1FZCC 1FZCB 2Q9IC 2JHLF 2Q9IB 1RE4B 4R9TA 2XNXC 2FIBA
chains in the Genus database with same CATH topology
1N86C 2JHIF 3GHGC 1N86B 2J61A 3BVHC 2HODC 3BVHB 1FIDA 2J60A 1FZDA 2OYIB 1FZAC 1LWUC 2H43C 4M7HA 1FZAB 2H43B 1RE3B 2OYHC 2GY7A 1FZEC 2OYHB 4JZCA 1FZEB 1RE4C 3E1IC 3H32B 2J61B 2HLOB 3E1IB 1RF1C 1RF1B 4R9JA 2J3FD 1N73C 2J5ZA 1N73B 2J0GA 2OYIC 2J3GA 2J2PA 1RE3C 2J3UA 2JHMF 3FIBA 2FFDC 3H32C 4JYOX 1JC9A 2FFDB 1FIBA 2HLOC 1M1JC 1M1JB 4NYTA 2HPCB 2J64A 2J1GA 2JHKF 2J3OA 2D39A 2JHHC 1LTJC 2Z4EC 2WNPF 1LTJB 2Z4EB 1LT9C 1FZBC 1LT9B 2J0YA 1FZBB 1Z3SA 2J3FA 1FICA 1FZGC 2XNXB 1FZGB 1Z3UA 4ZFGA 2HPCC 3HUSC 2HODB 3HUSB 4M7FA 1FZFC 1RF0C 4EPUA 1FZFB 1RF0B 1LWUB 2J0HA 1FZCC 1FZCB 2Q9IC 2JHLF 2Q9IB 1RE4B 4R9TA 2XNXC 2FIBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1N86 C;  2JHI F;  3GHG C;  1N86 B;  2J61 A;  3BVH C;  2HOD C;  3BVH B;  1FID A;  2J60 A;  1FZD A;  2OYI B;  1FZA C;  1LWU C;  2H43 C;  4M7H A;  1FZA B;  2H43 B;  1RE3 B;  2OYH C;  2GY7 A;  1FZE C;  2OYH B;  4JZC A;  1FZE B;  1RE4 C;  3E1I C;  3H32 B;  2J61 B;  2HLO B;  3E1I B;  1RF1 C;  1RF1 B;  4R9J A;  2J3F D;  1N73 C;  2J5Z A;  1N73 B;  2J0G A;  2OYI C;  2J3G A;  2J2P A;  1RE3 C;  2J3U A;  2JHM F;  3FIB A;  2FFD C;  3H32 C;  4JYO X;  1JC9 A;  2FFD B;  1FIB A;  2HLO C;  1M1J C;  1M1J B;  4NYT A;  2HPC B;  2J64 A;  2J1G A;  2JHK F;  2J3O A;  2D39 A;  2JHH C;  1LTJ C;  2Z4E C;  2WNP F;  1LTJ B;  2Z4E B;  1LT9 C;  1FZB C;  1LT9 B;  2J0Y A;  1FZB B;  1Z3S A;  2J3F A;  1FIC A;  1FZG C;  2XNX B;  1FZG B;  1Z3U A;  4ZFG A;  2HPC C;  3HUS C;  2HOD B;  3HUS B;  4M7F A;  1FZF C;  1RF0 C;  4EPU A;  1FZF B;  1RF0 B;  1LWU B;  2J0H A;  1FZC C;  1FZC B;  2Q9I C;  2JHL F;  2Q9I B;  1RE4 B;  4R9T A;  2XNX C;  2FIB A; 
#chains in the Genus database with same CATH topology
 1N86 C;  2JHI F;  3GHG C;  1N86 B;  2J61 A;  3GHG B;  3BVH C;  2HOD C;  3BVH B;  1FID A;  2J60 A;  1FZD A;  2OYI B;  1FZA C;  1LWU C;  2H43 C;  4M7H A;  1FZA B;  2H43 B;  1RE3 B;  2OYH C;  2GY7 A;  1FZE C;  2OYH B;  4JZC A;  1FZE B;  1RE4 C;  3E1I C;  3H32 B;  2J61 B;  2HLO B;  3E1I B;  1RF1 C;  1RF1 B;  4R9J A;  2J3F D;  1N73 C;  2J5Z A;  1N73 B;  2J0G A;  2OYI C;  2J3G A;  2J2P A;  1RE3 C;  2J3U A;  2JHM F;  3FIB A;  2FFD C;  3H32 C;  4JYO X;  1JC9 A;  2FFD B;  1FIB A;  2HLO C;  1M1J C;  1M1J B;  4NYT A;  2HPC B;  2J64 A;  2J1G A;  2JHK F;  2J3O A;  2D39 A;  2JHH C;  1LTJ C;  2Z4E C;  2WNP F;  1LTJ B;  2Z4E B;  1LT9 C;  1FZB C;  1LT9 B;  2J0Y A;  1FZB B;  1Z3S A;  2J3F A;  1FIC A;  1FZG C;  2XNX B;  1FZG B;  1Z3U A;  4ZFG A;  2HPC C;  3HUS C;  2HOD B;  3HUS B;  4M7F A;  1FZF C;  1RF0 C;  4EPU A;  1FZF B;  1RF0 B;  1LWU B;  2J0H A;  1FZC C;  1FZC B;  2Q9I C;  2JHL F;  2Q9I B;  1RE4 B;  4R9T A;  2XNX C;  2FIB A; 
#chains in the Genus database with same CATH homology
 1N86 C;  2JHI F;  3GHG C;  1N86 B;  2J61 A;  3BVH C;  2HOD C;  3BVH B;  1FID A;  2J60 A;  1FZD A;  2OYI B;  1FZA C;  1LWU C;  2H43 C;  4M7H A;  1FZA B;  2H43 B;  1RE3 B;  2OYH C;  2GY7 A;  1FZE C;  2OYH B;  4JZC A;  1FZE B;  1RE4 C;  3E1I C;  3H32 B;  2J61 B;  2HLO B;  3E1I B;  1RF1 C;  1RF1 B;  4R9J A;  2J3F D;  1N73 C;  2J5Z A;  1N73 B;  2J0G A;  2OYI C;  2J3G A;  2J2P A;  1RE3 C;  2J3U A;  2JHM F;  3FIB A;  2FFD C;  3H32 C;  4JYO X;  1JC9 A;  2FFD B;  1FIB A;  2HLO C;  1M1J C;  1M1J B;  4NYT A;  2HPC B;  2J64 A;  2J1G A;  2JHK F;  2J3O A;  2D39 A;  2JHH C;  1LTJ C;  2Z4E C;  2WNP F;  1LTJ B;  2Z4E B;  1LT9 C;  1FZB C;  1LT9 B;  2J0Y A;  1FZB B;  1Z3S A;  2J3F A;  1FIC A;  1FZG C;  2XNX B;  1FZG B;  1Z3U A;  4ZFG A;  2HPC C;  3HUS C;  2HOD B;  3HUS B;  4M7F A;  1FZF C;  1RF0 C;  4EPU A;  1FZF B;  1RF0 B;  1LWU B;  2J0H A;  1FZC C;  1FZC B;  2Q9I C;  2JHL F;  2Q9I B;  1RE4 B;  4R9T A;  2XNX C;  2FIB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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