2HLOB

Crystal structure of fragment d-dimer from human fibrin complexed with gly-hydroxypro-arg-pro-amide
Total Genus 91
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
91
sequence length
303
structure length
303
Chain Sequence
VNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKMSMKIRPFFP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Blood clotting
molecule keywords Fibrin alpha chain
total genus 91
structure length 303
sequence length 303
chains with identical sequence E
ec nomenclature
pdb deposition date 2006-07-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 2hloB01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 2hloB02
1Z3SA 1RE3B 1N86C 1FZBB 1RF1C 4R9JA 3BVHC 4EPUA 2FFDC 2JHLF 1N73B 3HUSB 1FZBC 4ZFGA 1FZGB 2J3FD 4M7HA 1RF0B 1N86B 3HUSC 2JHHC 1FZFC 2WNPF 1FZGC 2GY7A 2XNXB 3BVHB 1RF0C 2FFDB 2FIBA 1FZEC 1FZDA 4JYOX 2XNXC 2JHKF 4JZCA 4R9TA 2J3OA 2J3FA 1FZAC 1FZFB 4M7FA 2D39A 2HLOC 2JHIF 2J3GA 1FZEB 2Z4EC 1JC9A 1FICA 2J5ZA 2J64A 2J0GA 1FZAB 3E1IB 4NYTA 2OYIB 2J3UA 1M1JB 2HLOB 1LT9B 3H32C 2Z4EB 3E1IC 2OYIC 2J1GA 1M1JC 1FZCC 2OYHC 1RE4C 1LT9C 2J2PA 2HPCC 3GHGC 1FIBA 2J61A 2J0HA 2H43B 2HODB 1LWUC 2JHMF 1LTJB 3H32B 1RE3C 2Q9IB 2H43C 2J61B 2HODC 1FZCB 2OYHB 1RE4B 2HPCB 1LTJC 2J0YA 1N73C 3FIBA 2Q9IC 2J60A 1Z3UA 1RF1B 1LWUB 1FIDA
chains in the Genus database with same CATH superfamily
1Z3SA 1RE3B 1N86C 1FZBB 1RF1C 4R9JA 3BVHC 4EPUA 2FFDC 2JHLF 1N73B 3HUSB 1FZBC 4ZFGA 1FZGB 2J3FD 4M7HA 1RF0B 1N86B 3HUSC 2JHHC 1FZFC 2WNPF 1FZGC 2GY7A 2XNXB 3BVHB 1RF0C 2FFDB 2FIBA 1FZEC 1FZDA 4JYOX 2XNXC 2JHKF 4JZCA 4R9TA 2J3OA 2J3FA 1FZAC 1FZFB 4M7FA 2D39A 2HLOC 2JHIF 2J3GA 1FZEB 2Z4EC 1JC9A 1FICA 2J5ZA 2J64A 2J0GA 1FZAB 3E1IB 4NYTA 2OYIB 2J3UA 1M1JB 2HLOB 1LT9B 3H32C 2Z4EB 3E1IC 3GHGB 2OYIC 2J1GA 1M1JC 1FZCC 2OYHC 1RE4C 1LT9C 2J2PA 2HPCC 3GHGC 1FIBA 2J61A 2J0HA 2H43B 2HODB 1LWUC 2JHMF 1LTJB 3H32B 1RE3C 2Q9IB 2H43C 2J61B 2HODC 1FZCB 2OYHB 1RE4B 2HPCB 1LTJC 2J0YA 1N73C 3FIBA 2Q9IC 2J60A 1Z3UA 1RF1B 1LWUB 1FIDA
chains in the Genus database with same CATH topology
1Z3SA 1RE3B 1N86C 1FZBB 1RF1C 4R9JA 3BVHC 4EPUA 2FFDC 2JHLF 1N73B 3HUSB 1FZBC 4ZFGA 1FZGB 2J3FD 4M7HA 1RF0B 1N86B 3HUSC 2JHHC 1FZFC 2WNPF 1FZGC 2GY7A 2XNXB 3BVHB 1RF0C 2FFDB 2FIBA 1FZEC 1FZDA 4JYOX 2XNXC 2JHKF 4JZCA 4R9TA 2J3OA 2J3FA 1FZAC 1FZFB 4M7FA 2D39A 2HLOC 2JHIF 2J3GA 1FZEB 2Z4EC 1JC9A 1FICA 2J5ZA 2J64A 2J0GA 1FZAB 3E1IB 4NYTA 2OYIB 2J3UA 1M1JB 2HLOB 1LT9B 3H32C 2Z4EB 3E1IC 2OYIC 2J1GA 1M1JC 1FZCC 2OYHC 1RE4C 1LT9C 2J2PA 2HPCC 3GHGC 1FIBA 2J61A 2J0HA 2H43B 2HODB 1LWUC 2JHMF 1LTJB 3H32B 1RE3C 2Q9IB 2H43C 2J61B 2HODC 1FZCB 2OYHB 1RE4B 2HPCB 1LTJC 2J0YA 1N73C 3FIBA 2Q9IC 2J60A 1Z3UA 1RF1B 1LWUB 1FIDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1Z3S A;  1RE3 B;  1N86 C;  1FZB B;  1RF1 C;  4R9J A;  3BVH C;  4EPU A;  2FFD C;  2JHL F;  1N73 B;  3HUS B;  1FZB C;  4ZFG A;  1FZG B;  2J3F D;  4M7H A;  1RF0 B;  1N86 B;  3HUS C;  2JHH C;  1FZF C;  2WNP F;  1FZG C;  2GY7 A;  2XNX B;  3BVH B;  1RF0 C;  2FFD B;  2FIB A;  1FZE C;  1FZD A;  4JYO X;  2XNX C;  2JHK F;  4JZC A;  4R9T A;  2J3O A;  2J3F A;  1FZA C;  1FZF B;  4M7F A;  2D39 A;  2HLO C;  2JHI F;  2J3G A;  1FZE B;  2Z4E C;  1JC9 A;  1FIC A;  2J5Z A;  2J64 A;  2J0G A;  1FZA B;  3E1I B;  4NYT A;  2OYI B;  2J3U A;  1M1J B;  2HLO B;  1LT9 B;  3H32 C;  2Z4E B;  3E1I C;  2OYI C;  2J1G A;  1M1J C;  1FZC C;  2OYH C;  1RE4 C;  1LT9 C;  2J2P A;  2HPC C;  3GHG C;  1FIB A;  2J61 A;  2J0H A;  2H43 B;  2HOD B;  1LWU C;  2JHM F;  1LTJ B;  3H32 B;  1RE3 C;  2Q9I B;  2H43 C;  2J61 B;  2HOD C;  1FZC B;  2OYH B;  1RE4 B;  2HPC B;  1LTJ C;  2J0Y A;  1N73 C;  3FIB A;  2Q9I C;  2J60 A;  1Z3U A;  1RF1 B;  1LWU B;  1FID A; 
#chains in the Genus database with same CATH topology
 1Z3S A;  1RE3 B;  1N86 C;  1FZB B;  1RF1 C;  4R9J A;  3BVH C;  4EPU A;  2FFD C;  2JHL F;  1N73 B;  3HUS B;  1FZB C;  4ZFG A;  1FZG B;  2J3F D;  4M7H A;  1RF0 B;  1N86 B;  3HUS C;  2JHH C;  1FZF C;  2WNP F;  1FZG C;  2GY7 A;  2XNX B;  3BVH B;  1RF0 C;  2FFD B;  2FIB A;  1FZE C;  1FZD A;  4JYO X;  2XNX C;  2JHK F;  4JZC A;  4R9T A;  2J3O A;  2J3F A;  1FZA C;  1FZF B;  4M7F A;  2D39 A;  2HLO C;  2JHI F;  2J3G A;  1FZE B;  2Z4E C;  1JC9 A;  1FIC A;  2J5Z A;  2J64 A;  2J0G A;  1FZA B;  3E1I B;  4NYT A;  2OYI B;  2J3U A;  1M1J B;  2HLO B;  1LT9 B;  3H32 C;  2Z4E B;  3E1I C;  3GHG B;  2OYI C;  2J1G A;  1M1J C;  1FZC C;  2OYH C;  1RE4 C;  1LT9 C;  2J2P A;  2HPC C;  3GHG C;  1FIB A;  2J61 A;  2J0H A;  2H43 B;  2HOD B;  1LWU C;  2JHM F;  1LTJ B;  3H32 B;  1RE3 C;  2Q9I B;  2H43 C;  2J61 B;  2HOD C;  1FZC B;  2OYH B;  1RE4 B;  2HPC B;  1LTJ C;  2J0Y A;  1N73 C;  3FIB A;  2Q9I C;  2J60 A;  1Z3U A;  1RF1 B;  1LWU B;  1FID A; 
#chains in the Genus database with same CATH homology
 1Z3S A;  1RE3 B;  1N86 C;  1FZB B;  1RF1 C;  4R9J A;  3BVH C;  4EPU A;  2FFD C;  2JHL F;  1N73 B;  3HUS B;  1FZB C;  4ZFG A;  1FZG B;  2J3F D;  4M7H A;  1RF0 B;  1N86 B;  3HUS C;  2JHH C;  1FZF C;  2WNP F;  1FZG C;  2GY7 A;  2XNX B;  3BVH B;  1RF0 C;  2FFD B;  2FIB A;  1FZE C;  1FZD A;  4JYO X;  2XNX C;  2JHK F;  4JZC A;  4R9T A;  2J3O A;  2J3F A;  1FZA C;  1FZF B;  4M7F A;  2D39 A;  2HLO C;  2JHI F;  2J3G A;  1FZE B;  2Z4E C;  1JC9 A;  1FIC A;  2J5Z A;  2J64 A;  2J0G A;  1FZA B;  3E1I B;  4NYT A;  2OYI B;  2J3U A;  1M1J B;  2HLO B;  1LT9 B;  3H32 C;  2Z4E B;  3E1I C;  2OYI C;  2J1G A;  1M1J C;  1FZC C;  2OYH C;  1RE4 C;  1LT9 C;  2J2P A;  2HPC C;  3GHG C;  1FIB A;  2J61 A;  2J0H A;  2H43 B;  2HOD B;  1LWU C;  2JHM F;  1LTJ B;  3H32 B;  1RE3 C;  2Q9I B;  2H43 C;  2J61 B;  2HOD C;  1FZC B;  2OYH B;  1RE4 B;  2HPC B;  1LTJ C;  2J0Y A;  1N73 C;  3FIB A;  2Q9I C;  2J60 A;  1Z3U A;  1RF1 B;  1LWU B;  1FID A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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