2JHHC

Structure of globular heads of m-ficolin at acidic ph
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
217
structure length
208
Chain Sequence
SCATGPRNCKDLLDRGYFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRRMDGSVDFYRDWAAYKQGFGSQLGEFWLGNDNIHALTAQGSSELRTDLVDFEGNHQFAKYKSFKVADEAEKYKLVLGAFVGGSAGNSLTGHNNNFFSTKDQDNDVSSSNCAEKFQGAWWYADCHASNLNGLYLMGPHESYANGINWYKVSEMKVRPA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for innate immune sensing by M-ficolin and its control by a pH-dependent conformational switch.
pubmed doi rcsb
molecule tags Sugar binding protein
source organism Homo sapiens
molecule keywords FICOLIN-1
total genus 59
structure length 208
sequence length 217
chains with identical sequence F
ec nomenclature
pdb deposition date 2007-02-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 2jhhC01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 2jhhC02
2J1GA 2J61B 2Q9IC 1N86B 4M7HA 2FIBA 2J3UA 1N86C 2J60A 2HODB 1FZFB 1FZBB 1RE3B 2JHKF 1FIBA 2HODC 2JHIF 2J3GA 2Z4EB 1FZFC 4ZFGA 1M1JB 1RE3C 2WNPF 2J0HA 2JHLF 2HPCB 1RE4B 1RF0B 1LT9C 2D39A 2OYHB 2Z4EC 2J5ZA 1M1JC 1FZDA 4R9JA 1LWUB 2OYHC 4R9TA 4EPUA 2HLOB 1Z3UA 1FIDA 1LWUC 2H43B 2OYIB 3HUSB 3E1IB 2J3FD 1FZGB 2FFDB 2JHHC 1LTJB 3FIBA 2JHMF 2J61A 2H43C 2OYIC 3HUSC 1FZBC 3H32B 1FZGC 1FZEB 1LTJC 3GHGC 1Z3SA 1RF1B 2J64A 3BVHB 3H32C 1FICA 2HPCC 4M7FA 1FZCB 1RE4C 1RF0C 1RF1C 3BVHC 2J0GA 2Q9IB 2HLOC 2XNXB 1JC9A 2J0YA 3E1IC 2FFDC 4JYOX 2J3OA 2XNXC 4JZCA 1N73B 1FZAB 2J2PA 1FZEC 2GY7A 1N73C 2J3FA 1FZAC 1FZCC 4NYTA 1LT9B
chains in the Genus database with same CATH superfamily
2J1GA 2J61B 2Q9IC 1N86B 4M7HA 2FIBA 2J3UA 1N86C 2J60A 2HODB 1FZFB 1FZBB 1RE3B 2JHKF 3GHGB 1FIBA 2HODC 2JHIF 2J3GA 2Z4EB 1FZFC 4ZFGA 1M1JB 1RE3C 2WNPF 2J0HA 2JHLF 2HPCB 1RE4B 1RF0B 1LT9C 2D39A 2OYHB 2Z4EC 2J5ZA 1M1JC 1FZDA 4R9JA 1LWUB 2OYHC 4R9TA 4EPUA 2HLOB 1Z3UA 1FIDA 1LWUC 2H43B 2OYIB 3HUSB 3E1IB 2J3FD 1FZGB 2FFDB 2JHHC 1LTJB 3FIBA 2JHMF 2J61A 2H43C 2OYIC 3HUSC 1FZBC 3H32B 1FZGC 1FZEB 1LTJC 3GHGC 1Z3SA 1RF1B 2J64A 3BVHB 3H32C 1FICA 2HPCC 4M7FA 1FZCB 1RE4C 1RF0C 1RF1C 3BVHC 2J0GA 2Q9IB 2HLOC 2XNXB 1JC9A 2J0YA 3E1IC 2FFDC 4JYOX 2J3OA 2XNXC 4JZCA 1N73B 1FZAB 2J2PA 1FZEC 2GY7A 1N73C 2J3FA 1FZAC 1FZCC 4NYTA 1LT9B
chains in the Genus database with same CATH topology
2J1GA 2J61B 2Q9IC 1N86B 4M7HA 2FIBA 2J3UA 1N86C 2J60A 2HODB 1FZFB 1FZBB 1RE3B 2JHKF 1FIBA 2HODC 2JHIF 2J3GA 2Z4EB 1FZFC 4ZFGA 1M1JB 1RE3C 2WNPF 2J0HA 2JHLF 2HPCB 1RE4B 1RF0B 1LT9C 2D39A 2OYHB 2Z4EC 2J5ZA 1M1JC 1FZDA 4R9JA 1LWUB 2OYHC 4R9TA 4EPUA 2HLOB 1Z3UA 1FIDA 1LWUC 2H43B 2OYIB 3HUSB 3E1IB 2J3FD 1FZGB 2FFDB 2JHHC 1LTJB 3FIBA 2JHMF 2J61A 2H43C 2OYIC 3HUSC 1FZBC 3H32B 1FZGC 1FZEB 1LTJC 3GHGC 1Z3SA 1RF1B 2J64A 3BVHB 3H32C 1FICA 2HPCC 4M7FA 1FZCB 1RE4C 1RF0C 1RF1C 3BVHC 2J0GA 2Q9IB 2HLOC 2XNXB 1JC9A 2J0YA 3E1IC 2FFDC 4JYOX 2J3OA 2XNXC 4JZCA 1N73B 1FZAB 2J2PA 1FZEC 2GY7A 1N73C 2J3FA 1FZAC 1FZCC 4NYTA 1LT9B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2J1G A;  2J61 B;  2Q9I C;  1N86 B;  4M7H A;  2FIB A;  2J3U A;  1N86 C;  2J60 A;  2HOD B;  1FZF B;  1FZB B;  1RE3 B;  2JHK F;  1FIB A;  2HOD C;  2JHI F;  2J3G A;  2Z4E B;  1FZF C;  4ZFG A;  1M1J B;  1RE3 C;  2WNP F;  2J0H A;  2JHL F;  2HPC B;  1RE4 B;  1RF0 B;  1LT9 C;  2D39 A;  2OYH B;  2Z4E C;  2J5Z A;  1M1J C;  1FZD A;  4R9J A;  1LWU B;  2OYH C;  4R9T A;  4EPU A;  2HLO B;  1Z3U A;  1FID A;  1LWU C;  2H43 B;  2OYI B;  3HUS B;  3E1I B;  2J3F D;  1FZG B;  2FFD B;  2JHH C;  1LTJ B;  3FIB A;  2JHM F;  2J61 A;  2H43 C;  2OYI C;  3HUS C;  1FZB C;  3H32 B;  1FZG C;  1FZE B;  1LTJ C;  3GHG C;  1Z3S A;  1RF1 B;  2J64 A;  3BVH B;  3H32 C;  1FIC A;  2HPC C;  4M7F A;  1FZC B;  1RE4 C;  1RF0 C;  1RF1 C;  3BVH C;  2J0G A;  2Q9I B;  2HLO C;  2XNX B;  1JC9 A;  2J0Y A;  3E1I C;  2FFD C;  4JYO X;  2J3O A;  2XNX C;  4JZC A;  1N73 B;  1FZA B;  2J2P A;  1FZE C;  2GY7 A;  1N73 C;  2J3F A;  1FZA C;  1FZC C;  4NYT A;  1LT9 B; 
#chains in the Genus database with same CATH topology
 2J1G A;  2J61 B;  2Q9I C;  1N86 B;  4M7H A;  2FIB A;  2J3U A;  1N86 C;  2J60 A;  2HOD B;  1FZF B;  1FZB B;  1RE3 B;  2JHK F;  3GHG B;  1FIB A;  2HOD C;  2JHI F;  2J3G A;  2Z4E B;  1FZF C;  4ZFG A;  1M1J B;  1RE3 C;  2WNP F;  2J0H A;  2JHL F;  2HPC B;  1RE4 B;  1RF0 B;  1LT9 C;  2D39 A;  2OYH B;  2Z4E C;  2J5Z A;  1M1J C;  1FZD A;  4R9J A;  1LWU B;  2OYH C;  4R9T A;  4EPU A;  2HLO B;  1Z3U A;  1FID A;  1LWU C;  2H43 B;  2OYI B;  3HUS B;  3E1I B;  2J3F D;  1FZG B;  2FFD B;  2JHH C;  1LTJ B;  3FIB A;  2JHM F;  2J61 A;  2H43 C;  2OYI C;  3HUS C;  1FZB C;  3H32 B;  1FZG C;  1FZE B;  1LTJ C;  3GHG C;  1Z3S A;  1RF1 B;  2J64 A;  3BVH B;  3H32 C;  1FIC A;  2HPC C;  4M7F A;  1FZC B;  1RE4 C;  1RF0 C;  1RF1 C;  3BVH C;  2J0G A;  2Q9I B;  2HLO C;  2XNX B;  1JC9 A;  2J0Y A;  3E1I C;  2FFD C;  4JYO X;  2J3O A;  2XNX C;  4JZC A;  1N73 B;  1FZA B;  2J2P A;  1FZE C;  2GY7 A;  1N73 C;  2J3F A;  1FZA C;  1FZC C;  4NYT A;  1LT9 B; 
#chains in the Genus database with same CATH homology
 2J1G A;  2J61 B;  2Q9I C;  1N86 B;  4M7H A;  2FIB A;  2J3U A;  1N86 C;  2J60 A;  2HOD B;  1FZF B;  1FZB B;  1RE3 B;  2JHK F;  1FIB A;  2HOD C;  2JHI F;  2J3G A;  2Z4E B;  1FZF C;  4ZFG A;  1M1J B;  1RE3 C;  2WNP F;  2J0H A;  2JHL F;  2HPC B;  1RE4 B;  1RF0 B;  1LT9 C;  2D39 A;  2OYH B;  2Z4E C;  2J5Z A;  1M1J C;  1FZD A;  4R9J A;  1LWU B;  2OYH C;  4R9T A;  4EPU A;  2HLO B;  1Z3U A;  1FID A;  1LWU C;  2H43 B;  2OYI B;  3HUS B;  3E1I B;  2J3F D;  1FZG B;  2FFD B;  2JHH C;  1LTJ B;  3FIB A;  2JHM F;  2J61 A;  2H43 C;  2OYI C;  3HUS C;  1FZB C;  3H32 B;  1FZG C;  1FZE B;  1LTJ C;  3GHG C;  1Z3S A;  1RF1 B;  2J64 A;  3BVH B;  3H32 C;  1FIC A;  2HPC C;  4M7F A;  1FZC B;  1RE4 C;  1RF0 C;  1RF1 C;  3BVH C;  2J0G A;  2Q9I B;  2HLO C;  2XNX B;  1JC9 A;  2J0Y A;  3E1I C;  2FFD C;  4JYO X;  2J3O A;  2XNX C;  4JZC A;  1N73 B;  1FZA B;  2J2P A;  1FZE C;  2GY7 A;  1N73 C;  2J3F A;  1FZA C;  1FZC C;  4NYT A;  1LT9 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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