2JHMF

Structure of globular heads of m-ficolin at neutral ph
Total Genus 77
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
77
sequence length
217
structure length
217
Chain Sequence
SCATGPRNCKDLLDRGYFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRRMDGSVDFYRDWAAYKQGFGSQLGEFWLGNDNIHALTAQGSSELRTDLVDFEGNHQFAKYKSFKVADEAEKYKLVLGAFVGGSAGNSLTGHNNNFFSTKDQDNDVSSSNCAEKFQGAWWYADCHASNLNGLYLMGPHESYANGINWSAAKGYKYSYKVSEMKVRPA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Innate Immune Sensing by M-Ficolin and its Control by a Ph-Dependent Conformational Switch.
pubmed doi rcsb
molecule keywords FICOLIN-1
molecule tags Sugar binding protein
source organism Homo sapiens
total genus 77
structure length 217
sequence length 217
ec nomenclature
pdb deposition date 2007-02-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 2jhmF01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 2jhmF02
1FZGB 1FZCB 1LT9C 2XNXB 3GHGC 1JC9A 2WNPF 2J61B 3HUSC 2OYIB 1RE4B 2Z4EC 1M1JC 2J3OA 1FZAC 4M7HA 2HLOC 2J61A 2JHMF 2JHLF 1RF0C 1N86B 3FIBA 3E1IC 4JYOX 1Z3UA 2OYHB 2J0HA 4R9JA 1FZGC 2J3FA 1FZCC 2XNXC 2J0YA 2H43B 4M7FA 2OYIC 1RE4C 2J64A 1RF1B 1RE3C 1FICA 4EPUA 2JHKF 1FZFB 2Q9IB 4ZFGA 3H32B 1N86C 2D39A 1FIDA 2OYHC 1FZDA 3BVHB 2FFDB 2H43C 1FIBA 1FZBB 2J3UA 1N73B 1RF1C 2J3FD 2GY7A 1FZFC 2Q9IC 3H32C 4R9TA 1LWUB 2FIBA 2HPCB 1LTJB 2J1GA 3BVHC 2JHIF 4JZCA 2J5ZA 2FFDC 2J0GA 1FZEB 2HODB 1FZBC 1N73C 1LT9B 2JHHC 1LWUC 2HPCC 1RE3B 2J2PA 2J3GA 1LTJC 3HUSB 2Z4EB 1M1JB 4NYTA 1FZAB 2J60A 2HLOB 1RF0B 1FZEC 2HODC 1Z3SA 3E1IB
chains in the Genus database with same CATH superfamily
1FZGB 1FZCB 1LT9C 2XNXB 3GHGC 1JC9A 2WNPF 2J61B 3HUSC 2OYIB 1RE4B 2Z4EC 1M1JC 2J3OA 1FZAC 4M7HA 2HLOC 2J61A 2JHMF 2JHLF 1RF0C 1N86B 3FIBA 3E1IC 4JYOX 1Z3UA 2OYHB 2J0HA 4R9JA 1FZGC 2J3FA 1FZCC 2XNXC 2J0YA 2H43B 4M7FA 2OYIC 1RE4C 2J64A 1RF1B 1RE3C 1FICA 4EPUA 2JHKF 1FZFB 2Q9IB 4ZFGA 3H32B 1N86C 2D39A 1FIDA 2OYHC 1FZDA 3BVHB 2FFDB 2H43C 1FIBA 1FZBB 2J3UA 1N73B 1RF1C 2J3FD 2GY7A 1FZFC 2Q9IC 3H32C 4R9TA 1LWUB 2FIBA 2HPCB 1LTJB 2J1GA 3BVHC 2JHIF 4JZCA 2J5ZA 2FFDC 2J0GA 1FZEB 2HODB 1FZBC 1N73C 1LT9B 3GHGB 2JHHC 1LWUC 2HPCC 1RE3B 2J2PA 2J3GA 1LTJC 3HUSB 2Z4EB 1M1JB 4NYTA 1FZAB 2J60A 2HLOB 1RF0B 1FZEC 2HODC 1Z3SA 3E1IB
chains in the Genus database with same CATH topology
1FZGB 1FZCB 1LT9C 2XNXB 3GHGC 1JC9A 2WNPF 2J61B 3HUSC 2OYIB 1RE4B 2Z4EC 1M1JC 2J3OA 1FZAC 4M7HA 2HLOC 2J61A 2JHMF 2JHLF 1RF0C 1N86B 3FIBA 3E1IC 4JYOX 1Z3UA 2OYHB 2J0HA 4R9JA 1FZGC 2J3FA 1FZCC 2XNXC 2J0YA 2H43B 4M7FA 2OYIC 1RE4C 2J64A 1RF1B 1RE3C 1FICA 4EPUA 2JHKF 1FZFB 2Q9IB 4ZFGA 3H32B 1N86C 2D39A 1FIDA 2OYHC 1FZDA 3BVHB 2FFDB 2H43C 1FIBA 1FZBB 2J3UA 1N73B 1RF1C 2J3FD 2GY7A 1FZFC 2Q9IC 3H32C 4R9TA 1LWUB 2FIBA 2HPCB 1LTJB 2J1GA 3BVHC 2JHIF 4JZCA 2J5ZA 2FFDC 2J0GA 1FZEB 2HODB 1FZBC 1N73C 1LT9B 2JHHC 1LWUC 2HPCC 1RE3B 2J2PA 2J3GA 1LTJC 3HUSB 2Z4EB 1M1JB 4NYTA 1FZAB 2J60A 2HLOB 1RF0B 1FZEC 2HODC 1Z3SA 3E1IB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FZG B;  1FZC B;  1LT9 C;  2XNX B;  3GHG C;  1JC9 A;  2WNP F;  2J61 B;  3HUS C;  2OYI B;  1RE4 B;  2Z4E C;  1M1J C;  2J3O A;  1FZA C;  4M7H A;  2HLO C;  2J61 A;  2JHM F;  2JHL F;  1RF0 C;  1N86 B;  3FIB A;  3E1I C;  4JYO X;  1Z3U A;  2OYH B;  2J0H A;  4R9J A;  1FZG C;  2J3F A;  1FZC C;  2XNX C;  2J0Y A;  2H43 B;  4M7F A;  2OYI C;  1RE4 C;  2J64 A;  1RF1 B;  1RE3 C;  1FIC A;  4EPU A;  2JHK F;  1FZF B;  2Q9I B;  4ZFG A;  3H32 B;  1N86 C;  2D39 A;  1FID A;  2OYH C;  1FZD A;  3BVH B;  2FFD B;  2H43 C;  1FIB A;  1FZB B;  2J3U A;  1N73 B;  1RF1 C;  2J3F D;  2GY7 A;  1FZF C;  2Q9I C;  3H32 C;  4R9T A;  1LWU B;  2FIB A;  2HPC B;  1LTJ B;  2J1G A;  3BVH C;  2JHI F;  4JZC A;  2J5Z A;  2FFD C;  2J0G A;  1FZE B;  2HOD B;  1FZB C;  1N73 C;  1LT9 B;  2JHH C;  1LWU C;  2HPC C;  1RE3 B;  2J2P A;  2J3G A;  1LTJ C;  3HUS B;  2Z4E B;  1M1J B;  4NYT A;  1FZA B;  2J60 A;  2HLO B;  1RF0 B;  1FZE C;  2HOD C;  1Z3S A;  3E1I B; 
#chains in the Genus database with same CATH topology
 1FZG B;  1FZC B;  1LT9 C;  2XNX B;  3GHG C;  1JC9 A;  2WNP F;  2J61 B;  3HUS C;  2OYI B;  1RE4 B;  2Z4E C;  1M1J C;  2J3O A;  1FZA C;  4M7H A;  2HLO C;  2J61 A;  2JHM F;  2JHL F;  1RF0 C;  1N86 B;  3FIB A;  3E1I C;  4JYO X;  1Z3U A;  2OYH B;  2J0H A;  4R9J A;  1FZG C;  2J3F A;  1FZC C;  2XNX C;  2J0Y A;  2H43 B;  4M7F A;  2OYI C;  1RE4 C;  2J64 A;  1RF1 B;  1RE3 C;  1FIC A;  4EPU A;  2JHK F;  1FZF B;  2Q9I B;  4ZFG A;  3H32 B;  1N86 C;  2D39 A;  1FID A;  2OYH C;  1FZD A;  3BVH B;  2FFD B;  2H43 C;  1FIB A;  1FZB B;  2J3U A;  1N73 B;  1RF1 C;  2J3F D;  2GY7 A;  1FZF C;  2Q9I C;  3H32 C;  4R9T A;  1LWU B;  2FIB A;  2HPC B;  1LTJ B;  2J1G A;  3BVH C;  2JHI F;  4JZC A;  2J5Z A;  2FFD C;  2J0G A;  1FZE B;  2HOD B;  1FZB C;  1N73 C;  1LT9 B;  3GHG B;  2JHH C;  1LWU C;  2HPC C;  1RE3 B;  2J2P A;  2J3G A;  1LTJ C;  3HUS B;  2Z4E B;  1M1J B;  4NYT A;  1FZA B;  2J60 A;  2HLO B;  1RF0 B;  1FZE C;  2HOD C;  1Z3S A;  3E1I B; 
#chains in the Genus database with same CATH homology
 1FZG B;  1FZC B;  1LT9 C;  2XNX B;  3GHG C;  1JC9 A;  2WNP F;  2J61 B;  3HUS C;  2OYI B;  1RE4 B;  2Z4E C;  1M1J C;  2J3O A;  1FZA C;  4M7H A;  2HLO C;  2J61 A;  2JHM F;  2JHL F;  1RF0 C;  1N86 B;  3FIB A;  3E1I C;  4JYO X;  1Z3U A;  2OYH B;  2J0H A;  4R9J A;  1FZG C;  2J3F A;  1FZC C;  2XNX C;  2J0Y A;  2H43 B;  4M7F A;  2OYI C;  1RE4 C;  2J64 A;  1RF1 B;  1RE3 C;  1FIC A;  4EPU A;  2JHK F;  1FZF B;  2Q9I B;  4ZFG A;  3H32 B;  1N86 C;  2D39 A;  1FID A;  2OYH C;  1FZD A;  3BVH B;  2FFD B;  2H43 C;  1FIB A;  1FZB B;  2J3U A;  1N73 B;  1RF1 C;  2J3F D;  2GY7 A;  1FZF C;  2Q9I C;  3H32 C;  4R9T A;  1LWU B;  2FIB A;  2HPC B;  1LTJ B;  2J1G A;  3BVH C;  2JHI F;  4JZC A;  2J5Z A;  2FFD C;  2J0G A;  1FZE B;  2HOD B;  1FZB C;  1N73 C;  1LT9 B;  2JHH C;  1LWU C;  2HPC C;  1RE3 B;  2J2P A;  2J3G A;  1LTJ C;  3HUS B;  2Z4E B;  1M1J B;  4NYT A;  1FZA B;  2J60 A;  2HLO B;  1RF0 B;  1FZE C;  2HOD C;  1Z3S A;  3E1I B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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