1N86C

Crystal structure of human d-dimer from cross-linked fibrin complexed with gpr and ghrpldk peptide ligands.
Total Genus 76
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
76
sequence length
295
structure length
295
Chain Sequence
EASILTHDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHDITGKDCQDIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGWWMNKCHAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKIIPFNR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The crystal structure of fragment double-D from cross-linked lamprey fibrin reveals isopeptide linkages across an unexpected D-D interface.
pubmed doi rcsb
molecule tags Blood clotting
molecule keywords Fibrin alpha/alpha-E chain
total genus 76
structure length 295
sequence length 295
chains with identical sequence F
ec nomenclature
pdb deposition date 2002-11-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 1n86C01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 1n86C02
1LWUB 4R9JA 2OYIB 1M1JC 2HLOB 1N73C 2J5ZA 1N86B 1RE4C 1FICA 1LTJB 1LWUC 2OYIC 4M7FA 2JHLF 2HLOC 2HPCB 2J3FA 1N86C 2J3OA 1Z3UA 1LTJC 1FZAB 1RF1B 2J0YA 1RE3B 2HPCC 2J0HA 2J64A 3E1IB 2J3FD 4JYOX 1FZAC 1RF0C 2OYHB 1RF1C 2J0GA 1RE3C 2FIBA 4ZFGA 2HODB 2JHIF 2FFDB 3E1IC 2D39A 2OYHC 1FIBA 4M7HA 1JC9A 2Q9IB 3H32B 2HODC 2FFDC 1RF0B 1FZEB 2GY7A 4EPUA 2Q9IC 1FZDA 3H32C 4R9TA 1FZBB 3HUSB 2Z4EB 1FZEC 2J60A 1Z3SA 2J3UA 3FIBA 1FZBC 2J61A 2JHKF 3HUSC 2Z4EC 1FZGB 2J2PA 3BVHB 1FIDA 1FZGC 1FZCC 2JHMF 3BVHC 3GHGC 2J61B 2XNXB 2H43B 1FZFB 2J1GA 4NYTA 1LT9B 2XNXC 2H43C 1FZFC 1M1JB 4JZCA 1FZCB 2WNPF 1N73B 1RE4B 2J3GA 2JHHC 1LT9C
chains in the Genus database with same CATH superfamily
1LWUB 4R9JA 2OYIB 1M1JC 2HLOB 1N73C 2J5ZA 1N86B 1RE4C 1FICA 1LTJB 1LWUC 2OYIC 4M7FA 2JHLF 2HLOC 2HPCB 2J3FA 1N86C 2J3OA 1Z3UA 1LTJC 1FZAB 1RF1B 2J0YA 1RE3B 2HPCC 2J0HA 2J64A 3E1IB 2J3FD 4JYOX 1FZAC 1RF0C 2OYHB 1RF1C 2J0GA 1RE3C 2FIBA 4ZFGA 2HODB 2JHIF 2FFDB 3E1IC 2D39A 2OYHC 1FIBA 4M7HA 1JC9A 2Q9IB 3H32B 2HODC 2FFDC 1RF0B 1FZEB 2GY7A 4EPUA 2Q9IC 1FZDA 3H32C 4R9TA 1FZBB 3HUSB 2Z4EB 1FZEC 2J60A 1Z3SA 2J3UA 3FIBA 1FZBC 2J61A 2JHKF 3HUSC 2Z4EC 1FZGB 2J2PA 3BVHB 3GHGB 1FIDA 1FZGC 1FZCC 2JHMF 3BVHC 3GHGC 2J61B 2XNXB 2H43B 1FZFB 2J1GA 4NYTA 1LT9B 2XNXC 2H43C 1FZFC 1M1JB 4JZCA 1FZCB 2WNPF 1N73B 1RE4B 2J3GA 2JHHC 1LT9C
chains in the Genus database with same CATH topology
1LWUB 4R9JA 2OYIB 1M1JC 2HLOB 1N73C 2J5ZA 1N86B 1RE4C 1FICA 1LTJB 1LWUC 2OYIC 4M7FA 2JHLF 2HLOC 2HPCB 2J3FA 1N86C 2J3OA 1Z3UA 1LTJC 1FZAB 1RF1B 2J0YA 1RE3B 2HPCC 2J0HA 2J64A 3E1IB 2J3FD 4JYOX 1FZAC 1RF0C 2OYHB 1RF1C 2J0GA 1RE3C 2FIBA 4ZFGA 2HODB 2JHIF 2FFDB 3E1IC 2D39A 2OYHC 1FIBA 4M7HA 1JC9A 2Q9IB 3H32B 2HODC 2FFDC 1RF0B 1FZEB 2GY7A 4EPUA 2Q9IC 1FZDA 3H32C 4R9TA 1FZBB 3HUSB 2Z4EB 1FZEC 2J60A 1Z3SA 2J3UA 3FIBA 1FZBC 2J61A 2JHKF 3HUSC 2Z4EC 1FZGB 2J2PA 3BVHB 1FIDA 1FZGC 1FZCC 2JHMF 3BVHC 3GHGC 2J61B 2XNXB 2H43B 1FZFB 2J1GA 4NYTA 1LT9B 2XNXC 2H43C 1FZFC 1M1JB 4JZCA 1FZCB 2WNPF 1N73B 1RE4B 2J3GA 2JHHC 1LT9C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1LWU B;  4R9J A;  2OYI B;  1M1J C;  2HLO B;  1N73 C;  2J5Z A;  1N86 B;  1RE4 C;  1FIC A;  1LTJ B;  1LWU C;  2OYI C;  4M7F A;  2JHL F;  2HLO C;  2HPC B;  2J3F A;  1N86 C;  2J3O A;  1Z3U A;  1LTJ C;  1FZA B;  1RF1 B;  2J0Y A;  1RE3 B;  2HPC C;  2J0H A;  2J64 A;  3E1I B;  2J3F D;  4JYO X;  1FZA C;  1RF0 C;  2OYH B;  1RF1 C;  2J0G A;  1RE3 C;  2FIB A;  4ZFG A;  2HOD B;  2JHI F;  2FFD B;  3E1I C;  2D39 A;  2OYH C;  1FIB A;  4M7H A;  1JC9 A;  2Q9I B;  3H32 B;  2HOD C;  2FFD C;  1RF0 B;  1FZE B;  2GY7 A;  4EPU A;  2Q9I C;  1FZD A;  3H32 C;  4R9T A;  1FZB B;  3HUS B;  2Z4E B;  1FZE C;  2J60 A;  1Z3S A;  2J3U A;  3FIB A;  1FZB C;  2J61 A;  2JHK F;  3HUS C;  2Z4E C;  1FZG B;  2J2P A;  3BVH B;  1FID A;  1FZG C;  1FZC C;  2JHM F;  3BVH C;  3GHG C;  2J61 B;  2XNX B;  2H43 B;  1FZF B;  2J1G A;  4NYT A;  1LT9 B;  2XNX C;  2H43 C;  1FZF C;  1M1J B;  4JZC A;  1FZC B;  2WNP F;  1N73 B;  1RE4 B;  2J3G A;  2JHH C;  1LT9 C; 
#chains in the Genus database with same CATH topology
 1LWU B;  4R9J A;  2OYI B;  1M1J C;  2HLO B;  1N73 C;  2J5Z A;  1N86 B;  1RE4 C;  1FIC A;  1LTJ B;  1LWU C;  2OYI C;  4M7F A;  2JHL F;  2HLO C;  2HPC B;  2J3F A;  1N86 C;  2J3O A;  1Z3U A;  1LTJ C;  1FZA B;  1RF1 B;  2J0Y A;  1RE3 B;  2HPC C;  2J0H A;  2J64 A;  3E1I B;  2J3F D;  4JYO X;  1FZA C;  1RF0 C;  2OYH B;  1RF1 C;  2J0G A;  1RE3 C;  2FIB A;  4ZFG A;  2HOD B;  2JHI F;  2FFD B;  3E1I C;  2D39 A;  2OYH C;  1FIB A;  4M7H A;  1JC9 A;  2Q9I B;  3H32 B;  2HOD C;  2FFD C;  1RF0 B;  1FZE B;  2GY7 A;  4EPU A;  2Q9I C;  1FZD A;  3H32 C;  4R9T A;  1FZB B;  3HUS B;  2Z4E B;  1FZE C;  2J60 A;  1Z3S A;  2J3U A;  3FIB A;  1FZB C;  2J61 A;  2JHK F;  3HUS C;  2Z4E C;  1FZG B;  2J2P A;  3BVH B;  3GHG B;  1FID A;  1FZG C;  1FZC C;  2JHM F;  3BVH C;  3GHG C;  2J61 B;  2XNX B;  2H43 B;  1FZF B;  2J1G A;  4NYT A;  1LT9 B;  2XNX C;  2H43 C;  1FZF C;  1M1J B;  4JZC A;  1FZC B;  2WNP F;  1N73 B;  1RE4 B;  2J3G A;  2JHH C;  1LT9 C; 
#chains in the Genus database with same CATH homology
 1LWU B;  4R9J A;  2OYI B;  1M1J C;  2HLO B;  1N73 C;  2J5Z A;  1N86 B;  1RE4 C;  1FIC A;  1LTJ B;  1LWU C;  2OYI C;  4M7F A;  2JHL F;  2HLO C;  2HPC B;  2J3F A;  1N86 C;  2J3O A;  1Z3U A;  1LTJ C;  1FZA B;  1RF1 B;  2J0Y A;  1RE3 B;  2HPC C;  2J0H A;  2J64 A;  3E1I B;  2J3F D;  4JYO X;  1FZA C;  1RF0 C;  2OYH B;  1RF1 C;  2J0G A;  1RE3 C;  2FIB A;  4ZFG A;  2HOD B;  2JHI F;  2FFD B;  3E1I C;  2D39 A;  2OYH C;  1FIB A;  4M7H A;  1JC9 A;  2Q9I B;  3H32 B;  2HOD C;  2FFD C;  1RF0 B;  1FZE B;  2GY7 A;  4EPU A;  2Q9I C;  1FZD A;  3H32 C;  4R9T A;  1FZB B;  3HUS B;  2Z4E B;  1FZE C;  2J60 A;  1Z3S A;  2J3U A;  3FIB A;  1FZB C;  2J61 A;  2JHK F;  3HUS C;  2Z4E C;  1FZG B;  2J2P A;  3BVH B;  1FID A;  1FZG C;  1FZC C;  2JHM F;  3BVH C;  3GHG C;  2J61 B;  2XNX B;  2H43 B;  1FZF B;  2J1G A;  4NYT A;  1LT9 B;  2XNX C;  2H43 C;  1FZF C;  1M1J B;  4JZC A;  1FZC B;  2WNP F;  1N73 B;  1RE4 B;  2J3G A;  2JHH C;  1LT9 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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