2HLOC

Crystal structure of fragment d-dimer from human fibrin complexed with gly-hydroxypro-arg-pro-amide
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
292
structure length
292
Chain Sequence
THDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHDITGKDCQDIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGWWMNKCHAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKIIPFNRLT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Blood clotting
molecule keywords Fibrin alpha chain
total genus 81
structure length 292
sequence length 292
chains with identical sequence F
ec nomenclature
pdb deposition date 2006-07-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 2hloC01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 2hloC02
2J61A 2WNPF 1FZFC 1FZFB 2OYIB 2JHHC 1FZCC 1FZDA 1FZCB 1FICA 2Z4EC 4JYOX 1LWUC 2Q9IC 1FIDA 1RE3C 1RE3B 1RF1C 2XNXB 1RE4C 2J3UA 2HLOB 2FFDC 2GY7A 4M7FA 3BVHC 4ZFGA 3BVHB 2J3FA 1FZBB 2OYIC 3H32C 3H32B 4EPUA 2JHIF 1FZAB 4JZCA 1N73C 2JHLF 1N73B 1M1JB 3HUSC 3HUSB 1LTJB 1JC9A 2HPCB 2HODC 1FZGB 2XNXC 2HODB 2D39A 2HLOC 4R9JA 2FIBA 2J0GA 3GHGC 1FZEC 1FZBC 1FZEB 2OYHB 1RF0B 3FIBA 2J3FD 2JHMF 2J64A 1N86B 2J3GA 1FZAC 1M1JC 2JHKF 1LTJC 2HPCC 1FZGC 2J1GA 3E1IB 4M7HA 2J60A 1FIBA 1LT9C 1LT9B 2J5ZA 2H43C 2H43B 2OYHC 1RF0C 4NYTA 2Z4EB 1LWUB 1N86C 2Q9IB 2J0YA 2J0HA 1Z3UA 2J2PA 1RF1B 1RE4B 4R9TA 2FFDB 2J3OA 3E1IC 1Z3SA 2J61B
chains in the Genus database with same CATH superfamily
2J61A 2WNPF 1FZFC 1FZFB 2OYIB 2JHHC 1FZCC 1FZDA 1FZCB 1FICA 2Z4EC 4JYOX 1LWUC 2Q9IC 1FIDA 1RE3C 1RE3B 1RF1C 2XNXB 1RE4C 2J3UA 2HLOB 2FFDC 2GY7A 4M7FA 3BVHC 4ZFGA 3BVHB 2J3FA 1FZBB 2OYIC 3H32C 3H32B 4EPUA 2JHIF 1FZAB 4JZCA 1N73C 2JHLF 1N73B 1M1JB 3HUSC 3HUSB 1LTJB 1JC9A 2HPCB 2HODC 1FZGB 2XNXC 2HODB 2D39A 2HLOC 4R9JA 2FIBA 2J0GA 3GHGC 3GHGB 1FZEC 1FZBC 1FZEB 2OYHB 1RF0B 3FIBA 2J3FD 2JHMF 2J64A 1N86B 2J3GA 1FZAC 1M1JC 2JHKF 1LTJC 2HPCC 1FZGC 2J1GA 3E1IB 4M7HA 2J60A 1FIBA 1LT9C 1LT9B 2J5ZA 2H43C 2H43B 2OYHC 1RF0C 4NYTA 2Z4EB 1LWUB 1N86C 2Q9IB 2J0YA 2J0HA 1Z3UA 2J2PA 1RF1B 1RE4B 4R9TA 2FFDB 2J3OA 3E1IC 1Z3SA 2J61B
chains in the Genus database with same CATH topology
2J61A 2WNPF 1FZFC 1FZFB 2OYIB 2JHHC 1FZCC 1FZDA 1FZCB 1FICA 2Z4EC 4JYOX 1LWUC 2Q9IC 1FIDA 1RE3C 1RE3B 1RF1C 2XNXB 1RE4C 2J3UA 2HLOB 2FFDC 2GY7A 4M7FA 3BVHC 4ZFGA 3BVHB 2J3FA 1FZBB 2OYIC 3H32C 3H32B 4EPUA 2JHIF 1FZAB 4JZCA 1N73C 2JHLF 1N73B 1M1JB 3HUSC 3HUSB 1LTJB 1JC9A 2HPCB 2HODC 1FZGB 2XNXC 2HODB 2D39A 2HLOC 4R9JA 2FIBA 2J0GA 3GHGC 1FZEC 1FZBC 1FZEB 2OYHB 1RF0B 3FIBA 2J3FD 2JHMF 2J64A 1N86B 2J3GA 1FZAC 1M1JC 2JHKF 1LTJC 2HPCC 1FZGC 2J1GA 3E1IB 4M7HA 2J60A 1FIBA 1LT9C 1LT9B 2J5ZA 2H43C 2H43B 2OYHC 1RF0C 4NYTA 2Z4EB 1LWUB 1N86C 2Q9IB 2J0YA 2J0HA 1Z3UA 2J2PA 1RF1B 1RE4B 4R9TA 2FFDB 2J3OA 3E1IC 1Z3SA 2J61B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2J61 A;  2WNP F;  1FZF C;  1FZF B;  2OYI B;  2JHH C;  1FZC C;  1FZD A;  1FZC B;  1FIC A;  2Z4E C;  4JYO X;  1LWU C;  2Q9I C;  1FID A;  1RE3 C;  1RE3 B;  1RF1 C;  2XNX B;  1RE4 C;  2J3U A;  2HLO B;  2FFD C;  2GY7 A;  4M7F A;  3BVH C;  4ZFG A;  3BVH B;  2J3F A;  1FZB B;  2OYI C;  3H32 C;  3H32 B;  4EPU A;  2JHI F;  1FZA B;  4JZC A;  1N73 C;  2JHL F;  1N73 B;  1M1J B;  3HUS C;  3HUS B;  1LTJ B;  1JC9 A;  2HPC B;  2HOD C;  1FZG B;  2XNX C;  2HOD B;  2D39 A;  2HLO C;  4R9J A;  2FIB A;  2J0G A;  3GHG C;  1FZE C;  1FZB C;  1FZE B;  2OYH B;  1RF0 B;  3FIB A;  2J3F D;  2JHM F;  2J64 A;  1N86 B;  2J3G A;  1FZA C;  1M1J C;  2JHK F;  1LTJ C;  2HPC C;  1FZG C;  2J1G A;  3E1I B;  4M7H A;  2J60 A;  1FIB A;  1LT9 C;  1LT9 B;  2J5Z A;  2H43 C;  2H43 B;  2OYH C;  1RF0 C;  4NYT A;  2Z4E B;  1LWU B;  1N86 C;  2Q9I B;  2J0Y A;  2J0H A;  1Z3U A;  2J2P A;  1RF1 B;  1RE4 B;  4R9T A;  2FFD B;  2J3O A;  3E1I C;  1Z3S A;  2J61 B; 
#chains in the Genus database with same CATH topology
 2J61 A;  2WNP F;  1FZF C;  1FZF B;  2OYI B;  2JHH C;  1FZC C;  1FZD A;  1FZC B;  1FIC A;  2Z4E C;  4JYO X;  1LWU C;  2Q9I C;  1FID A;  1RE3 C;  1RE3 B;  1RF1 C;  2XNX B;  1RE4 C;  2J3U A;  2HLO B;  2FFD C;  2GY7 A;  4M7F A;  3BVH C;  4ZFG A;  3BVH B;  2J3F A;  1FZB B;  2OYI C;  3H32 C;  3H32 B;  4EPU A;  2JHI F;  1FZA B;  4JZC A;  1N73 C;  2JHL F;  1N73 B;  1M1J B;  3HUS C;  3HUS B;  1LTJ B;  1JC9 A;  2HPC B;  2HOD C;  1FZG B;  2XNX C;  2HOD B;  2D39 A;  2HLO C;  4R9J A;  2FIB A;  2J0G A;  3GHG C;  3GHG B;  1FZE C;  1FZB C;  1FZE B;  2OYH B;  1RF0 B;  3FIB A;  2J3F D;  2JHM F;  2J64 A;  1N86 B;  2J3G A;  1FZA C;  1M1J C;  2JHK F;  1LTJ C;  2HPC C;  1FZG C;  2J1G A;  3E1I B;  4M7H A;  2J60 A;  1FIB A;  1LT9 C;  1LT9 B;  2J5Z A;  2H43 C;  2H43 B;  2OYH C;  1RF0 C;  4NYT A;  2Z4E B;  1LWU B;  1N86 C;  2Q9I B;  2J0Y A;  2J0H A;  1Z3U A;  2J2P A;  1RF1 B;  1RE4 B;  4R9T A;  2FFD B;  2J3O A;  3E1I C;  1Z3S A;  2J61 B; 
#chains in the Genus database with same CATH homology
 2J61 A;  2WNP F;  1FZF C;  1FZF B;  2OYI B;  2JHH C;  1FZC C;  1FZD A;  1FZC B;  1FIC A;  2Z4E C;  4JYO X;  1LWU C;  2Q9I C;  1FID A;  1RE3 C;  1RE3 B;  1RF1 C;  2XNX B;  1RE4 C;  2J3U A;  2HLO B;  2FFD C;  2GY7 A;  4M7F A;  3BVH C;  4ZFG A;  3BVH B;  2J3F A;  1FZB B;  2OYI C;  3H32 C;  3H32 B;  4EPU A;  2JHI F;  1FZA B;  4JZC A;  1N73 C;  2JHL F;  1N73 B;  1M1J B;  3HUS C;  3HUS B;  1LTJ B;  1JC9 A;  2HPC B;  2HOD C;  1FZG B;  2XNX C;  2HOD B;  2D39 A;  2HLO C;  4R9J A;  2FIB A;  2J0G A;  3GHG C;  1FZE C;  1FZB C;  1FZE B;  2OYH B;  1RF0 B;  3FIB A;  2J3F D;  2JHM F;  2J64 A;  1N86 B;  2J3G A;  1FZA C;  1M1J C;  2JHK F;  1LTJ C;  2HPC C;  1FZG C;  2J1G A;  3E1I B;  4M7H A;  2J60 A;  1FIB A;  1LT9 C;  1LT9 B;  2J5Z A;  2H43 C;  2H43 B;  2OYH C;  1RF0 C;  4NYT A;  2Z4E B;  1LWU B;  1N86 C;  2Q9I B;  2J0Y A;  2J0H A;  1Z3U A;  2J2P A;  1RF1 B;  1RE4 B;  4R9T A;  2FFD B;  2J3O A;  3E1I C;  1Z3S A;  2J61 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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