1FZFB

Crystal structure of fragment double-d from human fibrin with the peptide ligand gly-his-arg-pro-amide
Total Genus 88
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
88
sequence length
303
structure length
303
Chain Sequence
VNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKMSMKIRPFFP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Conformational changes in fragments D and double-D from human fibrin(ogen) upon binding the peptide ligand Gly-His-Arg-Pro-amide.
pubmed doi rcsb
molecule keywords FIBRINOGEN
molecule tags Blood coagulation
total genus 88
structure length 303
sequence length 303
chains with identical sequence E
ec nomenclature
pdb deposition date 1998-12-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 1fzfB01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 1fzfB02
2XNXC 2HPCB 4NYTA 2FFDC 3BVHB 2J61B 3FIBA 1RE4B 2OYHB 2OYIC 1LTJC 1M1JC 2FIBA 1RE3B 1Z3UA 2J0GA 1LT9C 1FZEC 3HUSC 3E1IB 3H32C 1FZGB 2J2PA 1LWUB 1FZCB 2Q9IC 2JHKF 2HODB 2H43C 2GY7A 2J60A 1FZFC 2J3FA 3GHGC 1RF1C 2XNXB 2Z4EC 2FFDB 2JHMF 1FIDA 1Z3SA 2J0YA 2OYIB 1N73C 1LTJB 1M1JB 2J3UA 2WNPF 1FZBC 4JZCA 1FIBA 2HLOC 1RF0C 1N86C 1FZEB 1LT9B 1FZAC 3HUSB 1FZDA 4ZFGA 3H32B 2J3OA 2JHIF 3BVHC 2J64A 2J3FD 1JC9A 1RE4C 2D39A 2Q9IB 2H43B 2OYHC 2JHLF 4EPUA 2J0HA 1FZFB 1RE3C 1RF1B 1FICA 4R9JA 2Z4EB 3E1IC 4M7HA 1FZGC 1LWUC 2J5ZA 1N73B 2J1GA 1FZCC 1FZBB 2HPCC 2HLOB 4JYOX 1RF0B 1N86B 2HODC 2J3GA 2J61A 4M7FA 1FZAB 2JHHC 4R9TA
chains in the Genus database with same CATH superfamily
2XNXC 2HPCB 4NYTA 2FFDC 3BVHB 2J61B 3FIBA 1RE4B 2OYHB 2OYIC 1LTJC 1M1JC 2FIBA 1RE3B 1Z3UA 2J0GA 1LT9C 1FZEC 3HUSC 3E1IB 3H32C 1FZGB 2J2PA 1LWUB 1FZCB 2Q9IC 2JHKF 2HODB 2H43C 2GY7A 2J60A 1FZFC 2J3FA 3GHGC 1RF1C 2XNXB 2Z4EC 2FFDB 2JHMF 1FIDA 1Z3SA 2J0YA 2OYIB 1N73C 1LTJB 1M1JB 2J3UA 2WNPF 1FZBC 4JZCA 1FIBA 2HLOC 1RF0C 1N86C 1FZEB 1LT9B 1FZAC 3HUSB 1FZDA 4ZFGA 3H32B 2J3OA 2JHIF 3BVHC 2J64A 2J3FD 1JC9A 1RE4C 2D39A 2Q9IB 2H43B 2OYHC 2JHLF 4EPUA 2J0HA 1FZFB 1RE3C 3GHGB 1RF1B 1FICA 4R9JA 2Z4EB 3E1IC 4M7HA 1FZGC 1LWUC 2J5ZA 1N73B 2J1GA 1FZCC 1FZBB 2HPCC 2HLOB 4JYOX 1RF0B 1N86B 2HODC 2J3GA 2J61A 4M7FA 1FZAB 2JHHC 4R9TA
chains in the Genus database with same CATH topology
2XNXC 2HPCB 4NYTA 2FFDC 3BVHB 2J61B 3FIBA 1RE4B 2OYHB 2OYIC 1LTJC 1M1JC 2FIBA 1RE3B 1Z3UA 2J0GA 1LT9C 1FZEC 3HUSC 3E1IB 3H32C 1FZGB 2J2PA 1LWUB 1FZCB 2Q9IC 2JHKF 2HODB 2H43C 2GY7A 2J60A 1FZFC 2J3FA 3GHGC 1RF1C 2XNXB 2Z4EC 2FFDB 2JHMF 1FIDA 1Z3SA 2J0YA 2OYIB 1N73C 1LTJB 1M1JB 2J3UA 2WNPF 1FZBC 4JZCA 1FIBA 2HLOC 1RF0C 1N86C 1FZEB 1LT9B 1FZAC 3HUSB 1FZDA 4ZFGA 3H32B 2J3OA 2JHIF 3BVHC 2J64A 2J3FD 1JC9A 1RE4C 2D39A 2Q9IB 2H43B 2OYHC 2JHLF 4EPUA 2J0HA 1FZFB 1RE3C 1RF1B 1FICA 4R9JA 2Z4EB 3E1IC 4M7HA 1FZGC 1LWUC 2J5ZA 1N73B 2J1GA 1FZCC 1FZBB 2HPCC 2HLOB 4JYOX 1RF0B 1N86B 2HODC 2J3GA 2J61A 4M7FA 1FZAB 2JHHC 4R9TA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XNX C;  2HPC B;  4NYT A;  2FFD C;  3BVH B;  2J61 B;  3FIB A;  1RE4 B;  2OYH B;  2OYI C;  1LTJ C;  1M1J C;  2FIB A;  1RE3 B;  1Z3U A;  2J0G A;  1LT9 C;  1FZE C;  3HUS C;  3E1I B;  3H32 C;  1FZG B;  2J2P A;  1LWU B;  1FZC B;  2Q9I C;  2JHK F;  2HOD B;  2H43 C;  2GY7 A;  2J60 A;  1FZF C;  2J3F A;  3GHG C;  1RF1 C;  2XNX B;  2Z4E C;  2FFD B;  2JHM F;  1FID A;  1Z3S A;  2J0Y A;  2OYI B;  1N73 C;  1LTJ B;  1M1J B;  2J3U A;  2WNP F;  1FZB C;  4JZC A;  1FIB A;  2HLO C;  1RF0 C;  1N86 C;  1FZE B;  1LT9 B;  1FZA C;  3HUS B;  1FZD A;  4ZFG A;  3H32 B;  2J3O A;  2JHI F;  3BVH C;  2J64 A;  2J3F D;  1JC9 A;  1RE4 C;  2D39 A;  2Q9I B;  2H43 B;  2OYH C;  2JHL F;  4EPU A;  2J0H A;  1FZF B;  1RE3 C;  1RF1 B;  1FIC A;  4R9J A;  2Z4E B;  3E1I C;  4M7H A;  1FZG C;  1LWU C;  2J5Z A;  1N73 B;  2J1G A;  1FZC C;  1FZB B;  2HPC C;  2HLO B;  4JYO X;  1RF0 B;  1N86 B;  2HOD C;  2J3G A;  2J61 A;  4M7F A;  1FZA B;  2JHH C;  4R9T A; 
#chains in the Genus database with same CATH topology
 2XNX C;  2HPC B;  4NYT A;  2FFD C;  3BVH B;  2J61 B;  3FIB A;  1RE4 B;  2OYH B;  2OYI C;  1LTJ C;  1M1J C;  2FIB A;  1RE3 B;  1Z3U A;  2J0G A;  1LT9 C;  1FZE C;  3HUS C;  3E1I B;  3H32 C;  1FZG B;  2J2P A;  1LWU B;  1FZC B;  2Q9I C;  2JHK F;  2HOD B;  2H43 C;  2GY7 A;  2J60 A;  1FZF C;  2J3F A;  3GHG C;  1RF1 C;  2XNX B;  2Z4E C;  2FFD B;  2JHM F;  1FID A;  1Z3S A;  2J0Y A;  2OYI B;  1N73 C;  1LTJ B;  1M1J B;  2J3U A;  2WNP F;  1FZB C;  4JZC A;  1FIB A;  2HLO C;  1RF0 C;  1N86 C;  1FZE B;  1LT9 B;  1FZA C;  3HUS B;  1FZD A;  4ZFG A;  3H32 B;  2J3O A;  2JHI F;  3BVH C;  2J64 A;  2J3F D;  1JC9 A;  1RE4 C;  2D39 A;  2Q9I B;  2H43 B;  2OYH C;  2JHL F;  4EPU A;  2J0H A;  1FZF B;  1RE3 C;  3GHG B;  1RF1 B;  1FIC A;  4R9J A;  2Z4E B;  3E1I C;  4M7H A;  1FZG C;  1LWU C;  2J5Z A;  1N73 B;  2J1G A;  1FZC C;  1FZB B;  2HPC C;  2HLO B;  4JYO X;  1RF0 B;  1N86 B;  2HOD C;  2J3G A;  2J61 A;  4M7F A;  1FZA B;  2JHH C;  4R9T A; 
#chains in the Genus database with same CATH homology
 2XNX C;  2HPC B;  4NYT A;  2FFD C;  3BVH B;  2J61 B;  3FIB A;  1RE4 B;  2OYH B;  2OYI C;  1LTJ C;  1M1J C;  2FIB A;  1RE3 B;  1Z3U A;  2J0G A;  1LT9 C;  1FZE C;  3HUS C;  3E1I B;  3H32 C;  1FZG B;  2J2P A;  1LWU B;  1FZC B;  2Q9I C;  2JHK F;  2HOD B;  2H43 C;  2GY7 A;  2J60 A;  1FZF C;  2J3F A;  3GHG C;  1RF1 C;  2XNX B;  2Z4E C;  2FFD B;  2JHM F;  1FID A;  1Z3S A;  2J0Y A;  2OYI B;  1N73 C;  1LTJ B;  1M1J B;  2J3U A;  2WNP F;  1FZB C;  4JZC A;  1FIB A;  2HLO C;  1RF0 C;  1N86 C;  1FZE B;  1LT9 B;  1FZA C;  3HUS B;  1FZD A;  4ZFG A;  3H32 B;  2J3O A;  2JHI F;  3BVH C;  2J64 A;  2J3F D;  1JC9 A;  1RE4 C;  2D39 A;  2Q9I B;  2H43 B;  2OYH C;  2JHL F;  4EPU A;  2J0H A;  1FZF B;  1RE3 C;  1RF1 B;  1FIC A;  4R9J A;  2Z4E B;  3E1I C;  4M7H A;  1FZG C;  1LWU C;  2J5Z A;  1N73 B;  2J1G A;  1FZC C;  1FZB B;  2HPC C;  2HLO B;  4JYO X;  1RF0 B;  1N86 B;  2HOD C;  2J3G A;  2J61 A;  4M7F A;  1FZA B;  2JHH C;  4R9T A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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