2Q9IB

Crystal structure of d-dimer from human fibrin complexed with met-his-arg-pro-tyr-amide.
Total Genus 90
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
90
sequence length
303
structure length
303
Chain Sequence
VNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKMSMKIRPFFP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Probing the beta-chain hole of fibrinogen with synthetic peptides that differ at their amino termini
pubmed doi rcsb
molecule keywords Fibrinogen alpha chain
molecule tags Blood clotting
total genus 90
structure length 303
sequence length 303
chains with identical sequence E
ec nomenclature
pdb deposition date 2007-06-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 2q9iB01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 2q9iB02
1LT9B 2OYHB 2JHIF 2J3FD 2HPCB 1Z3UA 2Q9IC 4M7HA 3H32B 2HODC 2J0GA 2Z4EB 2WNPF 4R9JA 2J1GA 2H43B 2FFDC 2JHHC 1FZGB 1FZCB 1FZAC 3BVHC 1JC9A 2HLOC 1FZBB 2OYIC 1LT9C 2OYHC 1Z3SA 2XNXB 2HPCC 1FIDA 2JHMF 3H32C 2J61B 2FIBA 2J0YA 1FIBA 2J60A 2H43C 1FZDA 1FZGC 1FZCC 1N86B 1RE4C 1FZBC 1FZEB 4ZFGA 1RE3B 3FIBA 2XNXC 4JYOX 3E1IB 4R9TA 1RF0B 2J3FA 1FICA 1N86C 2Z4EC 1RF1B 1FZEC 2GY7A 4NYTA 1RE3C 3HUSB 1LWUC 3GHGC 3E1IC 2J3GA 2J5ZA 1RF0C 1LTJB 1N73B 2J0HA 2JHLF 1FZFB 1LWUB 1M1JB 1RF1C 2J3OA 4M7FA 3HUSC 2Q9IB 2J64A 4JZCA 2HODB 1RE4B 2D39A 2FFDB 2J2PA 1LTJC 1FZAB 3BVHB 2HLOB 2J3UA 1N73C 2JHKF 2OYIB 1FZFC 1M1JC 4EPUA 2J61A
chains in the Genus database with same CATH superfamily
1LT9B 2OYHB 2JHIF 2J3FD 2HPCB 1Z3UA 2Q9IC 4M7HA 3H32B 2HODC 2J0GA 2Z4EB 2WNPF 4R9JA 2J1GA 2H43B 2FFDC 2JHHC 1FZGB 1FZCB 1FZAC 3BVHC 1JC9A 2HLOC 1FZBB 2OYIC 1LT9C 2OYHC 1Z3SA 2XNXB 2HPCC 1FIDA 2JHMF 3H32C 2J61B 2FIBA 2J0YA 1FIBA 2J60A 2H43C 1FZDA 1FZGC 1FZCC 1N86B 1RE4C 1FZBC 1FZEB 4ZFGA 1RE3B 3FIBA 2XNXC 4JYOX 3GHGB 3E1IB 4R9TA 1RF0B 2J3FA 1FICA 1N86C 2Z4EC 1RF1B 1FZEC 2GY7A 4NYTA 1RE3C 3HUSB 1LWUC 3GHGC 3E1IC 2J3GA 2J5ZA 1RF0C 1LTJB 1N73B 2J0HA 2JHLF 1FZFB 1LWUB 1M1JB 1RF1C 2J3OA 4M7FA 3HUSC 2Q9IB 2J64A 4JZCA 2HODB 1RE4B 2D39A 2FFDB 2J2PA 1LTJC 1FZAB 3BVHB 2HLOB 2J3UA 1N73C 2JHKF 2OYIB 1FZFC 1M1JC 4EPUA 2J61A
chains in the Genus database with same CATH topology
1LT9B 2OYHB 2JHIF 2J3FD 2HPCB 1Z3UA 2Q9IC 4M7HA 3H32B 2HODC 2J0GA 2Z4EB 2WNPF 4R9JA 2J1GA 2H43B 2FFDC 2JHHC 1FZGB 1FZCB 1FZAC 3BVHC 1JC9A 2HLOC 1FZBB 2OYIC 1LT9C 2OYHC 1Z3SA 2XNXB 2HPCC 1FIDA 2JHMF 3H32C 2J61B 2FIBA 2J0YA 1FIBA 2J60A 2H43C 1FZDA 1FZGC 1FZCC 1N86B 1RE4C 1FZBC 1FZEB 4ZFGA 1RE3B 3FIBA 2XNXC 4JYOX 3E1IB 4R9TA 1RF0B 2J3FA 1FICA 1N86C 2Z4EC 1RF1B 1FZEC 2GY7A 4NYTA 1RE3C 3HUSB 1LWUC 3GHGC 3E1IC 2J3GA 2J5ZA 1RF0C 1LTJB 1N73B 2J0HA 2JHLF 1FZFB 1LWUB 1M1JB 1RF1C 2J3OA 4M7FA 3HUSC 2Q9IB 2J64A 4JZCA 2HODB 1RE4B 2D39A 2FFDB 2J2PA 1LTJC 1FZAB 3BVHB 2HLOB 2J3UA 1N73C 2JHKF 2OYIB 1FZFC 1M1JC 4EPUA 2J61A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1LT9 B;  2OYH B;  2JHI F;  2J3F D;  2HPC B;  1Z3U A;  2Q9I C;  4M7H A;  3H32 B;  2HOD C;  2J0G A;  2Z4E B;  2WNP F;  4R9J A;  2J1G A;  2H43 B;  2FFD C;  2JHH C;  1FZG B;  1FZC B;  1FZA C;  3BVH C;  1JC9 A;  2HLO C;  1FZB B;  2OYI C;  1LT9 C;  2OYH C;  1Z3S A;  2XNX B;  2HPC C;  1FID A;  2JHM F;  3H32 C;  2J61 B;  2FIB A;  2J0Y A;  1FIB A;  2J60 A;  2H43 C;  1FZD A;  1FZG C;  1FZC C;  1N86 B;  1RE4 C;  1FZB C;  1FZE B;  4ZFG A;  1RE3 B;  3FIB A;  2XNX C;  4JYO X;  3E1I B;  4R9T A;  1RF0 B;  2J3F A;  1FIC A;  1N86 C;  2Z4E C;  1RF1 B;  1FZE C;  2GY7 A;  4NYT A;  1RE3 C;  3HUS B;  1LWU C;  3GHG C;  3E1I C;  2J3G A;  2J5Z A;  1RF0 C;  1LTJ B;  1N73 B;  2J0H A;  2JHL F;  1FZF B;  1LWU B;  1M1J B;  1RF1 C;  2J3O A;  4M7F A;  3HUS C;  2Q9I B;  2J64 A;  4JZC A;  2HOD B;  1RE4 B;  2D39 A;  2FFD B;  2J2P A;  1LTJ C;  1FZA B;  3BVH B;  2HLO B;  2J3U A;  1N73 C;  2JHK F;  2OYI B;  1FZF C;  1M1J C;  4EPU A;  2J61 A; 
#chains in the Genus database with same CATH topology
 1LT9 B;  2OYH B;  2JHI F;  2J3F D;  2HPC B;  1Z3U A;  2Q9I C;  4M7H A;  3H32 B;  2HOD C;  2J0G A;  2Z4E B;  2WNP F;  4R9J A;  2J1G A;  2H43 B;  2FFD C;  2JHH C;  1FZG B;  1FZC B;  1FZA C;  3BVH C;  1JC9 A;  2HLO C;  1FZB B;  2OYI C;  1LT9 C;  2OYH C;  1Z3S A;  2XNX B;  2HPC C;  1FID A;  2JHM F;  3H32 C;  2J61 B;  2FIB A;  2J0Y A;  1FIB A;  2J60 A;  2H43 C;  1FZD A;  1FZG C;  1FZC C;  1N86 B;  1RE4 C;  1FZB C;  1FZE B;  4ZFG A;  1RE3 B;  3FIB A;  2XNX C;  4JYO X;  3GHG B;  3E1I B;  4R9T A;  1RF0 B;  2J3F A;  1FIC A;  1N86 C;  2Z4E C;  1RF1 B;  1FZE C;  2GY7 A;  4NYT A;  1RE3 C;  3HUS B;  1LWU C;  3GHG C;  3E1I C;  2J3G A;  2J5Z A;  1RF0 C;  1LTJ B;  1N73 B;  2J0H A;  2JHL F;  1FZF B;  1LWU B;  1M1J B;  1RF1 C;  2J3O A;  4M7F A;  3HUS C;  2Q9I B;  2J64 A;  4JZC A;  2HOD B;  1RE4 B;  2D39 A;  2FFD B;  2J2P A;  1LTJ C;  1FZA B;  3BVH B;  2HLO B;  2J3U A;  1N73 C;  2JHK F;  2OYI B;  1FZF C;  1M1J C;  4EPU A;  2J61 A; 
#chains in the Genus database with same CATH homology
 1LT9 B;  2OYH B;  2JHI F;  2J3F D;  2HPC B;  1Z3U A;  2Q9I C;  4M7H A;  3H32 B;  2HOD C;  2J0G A;  2Z4E B;  2WNP F;  4R9J A;  2J1G A;  2H43 B;  2FFD C;  2JHH C;  1FZG B;  1FZC B;  1FZA C;  3BVH C;  1JC9 A;  2HLO C;  1FZB B;  2OYI C;  1LT9 C;  2OYH C;  1Z3S A;  2XNX B;  2HPC C;  1FID A;  2JHM F;  3H32 C;  2J61 B;  2FIB A;  2J0Y A;  1FIB A;  2J60 A;  2H43 C;  1FZD A;  1FZG C;  1FZC C;  1N86 B;  1RE4 C;  1FZB C;  1FZE B;  4ZFG A;  1RE3 B;  3FIB A;  2XNX C;  4JYO X;  3E1I B;  4R9T A;  1RF0 B;  2J3F A;  1FIC A;  1N86 C;  2Z4E C;  1RF1 B;  1FZE C;  2GY7 A;  4NYT A;  1RE3 C;  3HUS B;  1LWU C;  3GHG C;  3E1I C;  2J3G A;  2J5Z A;  1RF0 C;  1LTJ B;  1N73 B;  2J0H A;  2JHL F;  1FZF B;  1LWU B;  1M1J B;  1RF1 C;  2J3O A;  4M7F A;  3HUS C;  2Q9I B;  2J64 A;  4JZC A;  2HOD B;  1RE4 B;  2D39 A;  2FFD B;  2J2P A;  1LTJ C;  1FZA B;  3BVH B;  2HLO B;  2J3U A;  1N73 C;  2JHK F;  2OYI B;  1FZF C;  1M1J C;  4EPU A;  2J61 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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