1FZEB

Crystal structure of fragment double-d from human fibrin
Total Genus 94

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
94
sequence length
309
structure length
309
Chain Sequence
LYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKMSMKIRPFFP

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
EMPTYS3 (249-255)AH1 (162-193)O10 (153-182)TIV1 (154-157)TIV2 (155-158)TIV3 (156-159)TIV4 (157-160)AH4 (296-304)TIV5 (158-161)TIV8 (230-233)TVIII1 (193-196)O7 (201-286)TIV7 (208-211)S6 (288-289)S1 (223-227)TIV9 (241-244)S2 (236-241)TIV10 (243-246)TIV11 (244-247)TIV13 (261-264)TIV12 (255-258)TII1 (280-283)AH3 (266-271)S4 (273-274)S5 (277-278)S7 (292-293)AH2 (211-217)Updating...
connected with : NaN
molecule tags Blood coagulation
publication title Conformational changes in fragments D and double-D from human fibrin(ogen) upon binding the peptide ligand Gly-His-Arg-Pro-amide.
pubmed doi rcsb
molecule keywords FIBRINOGEN
total genus 94
structure length 309
sequence length 309
chains with identical sequence E
ec nomenclature
pdb deposition date 1998-12-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 1fzeB01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 1fzeB02
1N73B 1FZBB 1LWUC 2XNXC 2J2PA 2JHMF 3BVHC 2J3GA 1FZCB 2H43C 3E1IB 2J61A 2OYIC 2HPCB 1FZGB 2HLOB 1RE4C 4JZCA 1JC9A 4M7HA 2Q9IC 2OYHB 2J1GA 3H32C 1LTJB 2HODC 1FZEC 1Z3SA 2JHLF 1RF1B 1N86C 1FZAB 3HUSB 1LT9B 2J0GA 4M7FA 1FZBC 1FICA 1M1JC 1RF0B 4R9TA 1FZFC 1LWUB 2J60A 2J3FD 2XNXB 3GHGC 2FFDC 3BVHB 2J3UA 2Z4EC 2H43B 2OYIB 4EPUA 2D39A 1RE3C 1N73C 1RE4B 1FIBA 2Q9IB 2J0YA 2J64A 2J3FA 3H32B 2HODB 1FZEB 1N86B 2FIBA 1FZCC 3E1IC 2HPCC 2J0HA 2J5ZA 2JHKF 2J3OA 1FZGC 2HLOC 1FIDA 1M1JB 1FZFB 2JHHC 2GY7A 1Z3UA 2OYHC 4R9JA 2J61B 1LTJC 4NYTA 2FFDB 1RF1C 4JYOX 2Z4EB 1FZAC 3HUSC 1LT9C 1FZDA 2JHIF 4ZFGA 2WNPF 1RF0C 1RE3B 3FIBA
chains in the Genus database with same CATH superfamily
1N73B 1FZBB 1LWUC 2XNXC 2J2PA 2JHMF 3BVHC 2J3GA 1FZCB 2H43C 3E1IB 2J61A 2OYIC 2HPCB 1FZGB 2HLOB 1RE4C 4JZCA 1JC9A 4M7HA 2Q9IC 2OYHB 2J1GA 3H32C 1LTJB 2HODC 1FZEC 1Z3SA 2JHLF 1RF1B 1N86C 1FZAB 3HUSB 1LT9B 2J0GA 4M7FA 1FZBC 1FICA 1M1JC 1RF0B 4R9TA 1FZFC 1LWUB 2J60A 2J3FD 2XNXB 3GHGC 2FFDC 3BVHB 2J3UA 2Z4EC 2H43B 2OYIB 4EPUA 2D39A 1RE3C 1N73C 1RE4B 1FIBA 2Q9IB 2J0YA 2J64A 2J3FA 3H32B 2HODB 1FZEB 1N86B 2FIBA 1FZCC 3E1IC 2J0HA 2J5ZA 2HPCC 2JHKF 2J3OA 1FZGC 2HLOC 1FIDA 1M1JB 1FZFB 2JHHC 2GY7A 1Z3UA 2OYHC 4R9JA 2J61B 1LTJC 4NYTA 3GHGB 2FFDB 1RF1C 4JYOX 2Z4EB 1FZAC 3HUSC 1LT9C 1FZDA 2JHIF 4ZFGA 2WNPF 1RF0C 1RE3B 3FIBA
chains in the Genus database with same CATH topology
1N73B 1FZBB 1LWUC 2XNXC 2J2PA 2JHMF 3BVHC 2J3GA 1FZCB 2H43C 3E1IB 2J61A 2OYIC 2HPCB 1FZGB 2HLOB 1RE4C 4JZCA 1JC9A 4M7HA 2Q9IC 2OYHB 2J1GA 3H32C 1LTJB 2HODC 1FZEC 1Z3SA 2JHLF 1RF1B 1N86C 1FZAB 3HUSB 1LT9B 2J0GA 4M7FA 1FZBC 1FICA 1M1JC 1RF0B 4R9TA 1FZFC 1LWUB 2J60A 2J3FD 2XNXB 3GHGC 2FFDC 3BVHB 2J3UA 2Z4EC 2H43B 2OYIB 4EPUA 2D39A 1RE3C 1N73C 1RE4B 1FIBA 2Q9IB 2J0YA 2J64A 2J3FA 3H32B 2HODB 1FZEB 1N86B 2FIBA 1FZCC 3E1IC 2HPCC 2J0HA 2J5ZA 2JHKF 2J3OA 1FZGC 2HLOC 1FIDA 1M1JB 1FZFB 2JHHC 2GY7A 1Z3UA 2OYHC 4R9JA 2J61B 1LTJC 4NYTA 2FFDB 1RF1C 4JYOX 2Z4EB 1FZAC 3HUSC 1LT9C 1FZDA 2JHIF 4ZFGA 2WNPF 1RF0C 1RE3B 3FIBA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 1N73 B;  1FZB B;  1LWU C;  2XNX C;  2J2P A;  2JHM F;  3BVH C;  2J3G A;  1FZC B;  2H43 C;  3E1I B;  2J61 A;  2OYI C;  2HPC B;  1FZG B;  2HLO B;  1RE4 C;  4JZC A;  1JC9 A;  4M7H A;  2Q9I C;  2OYH B;  2J1G A;  3H32 C;  1LTJ B;  2HOD C;  1FZE C;  1Z3S A;  2JHL F;  1RF1 B;  1N86 C;  1FZA B;  3HUS B;  1LT9 B;  2J0G A;  4M7F A;  1FZB C;  1FIC A;  1M1J C;  1RF0 B;  4R9T A;  1FZF C;  1LWU B;  2J60 A;  2J3F D;  2XNX B;  3GHG C;  2FFD C;  3BVH B;  2J3U A;  2Z4E C;  2H43 B;  2OYI B;  4EPU A;  2D39 A;  1RE3 C;  1N73 C;  1RE4 B;  1FIB A;  2Q9I B;  2J0Y A;  2J64 A;  2J3F A;  3H32 B;  2HOD B;  1FZE B;  1N86 B;  2FIB A;  1FZC C;  3E1I C;  2HPC C;  2J0H A;  2J5Z A;  2JHK F;  2J3O A;  1FZG C;  2HLO C;  1FID A;  1M1J B;  1FZF B;  2JHH C;  2GY7 A;  1Z3U A;  2OYH C;  4R9J A;  2J61 B;  1LTJ C;  4NYT A;  2FFD B;  1RF1 C;  4JYO X;  2Z4E B;  1FZA C;  3HUS C;  1LT9 C;  1FZD A;  2JHI F;  4ZFG A;  2WNP F;  1RF0 C;  1RE3 B;  3FIB A; 
#chains in the Genus database with same CATH topology
 1N73 B;  1FZB B;  1LWU C;  2XNX C;  2J2P A;  2JHM F;  3BVH C;  2J3G A;  1FZC B;  2H43 C;  3E1I B;  2J61 A;  2OYI C;  2HPC B;  1FZG B;  2HLO B;  1RE4 C;  4JZC A;  1JC9 A;  4M7H A;  2Q9I C;  2OYH B;  2J1G A;  3H32 C;  1LTJ B;  2HOD C;  1FZE C;  1Z3S A;  2JHL F;  1RF1 B;  1N86 C;  1FZA B;  3HUS B;  1LT9 B;  2J0G A;  4M7F A;  1FZB C;  1FIC A;  1M1J C;  1RF0 B;  4R9T A;  1FZF C;  1LWU B;  2J60 A;  2J3F D;  2XNX B;  3GHG C;  2FFD C;  3BVH B;  2J3U A;  2Z4E C;  2H43 B;  2OYI B;  4EPU A;  2D39 A;  1RE3 C;  1N73 C;  1RE4 B;  1FIB A;  2Q9I B;  2J0Y A;  2J64 A;  2J3F A;  3H32 B;  2HOD B;  1FZE B;  1N86 B;  2FIB A;  1FZC C;  3E1I C;  2J0H A;  2J5Z A;  2HPC C;  2JHK F;  2J3O A;  1FZG C;  2HLO C;  1FID A;  1M1J B;  1FZF B;  2JHH C;  2GY7 A;  1Z3U A;  2OYH C;  4R9J A;  2J61 B;  1LTJ C;  4NYT A;  3GHG B;  2FFD B;  1RF1 C;  4JYO X;  2Z4E B;  1FZA C;  3HUS C;  1LT9 C;  1FZD A;  2JHI F;  4ZFG A;  2WNP F;  1RF0 C;  1RE3 B;  3FIB A; 
#chains in the Genus database with same CATH homology
 1N73 B;  1FZB B;  1LWU C;  2XNX C;  2J2P A;  2JHM F;  3BVH C;  2J3G A;  1FZC B;  2H43 C;  3E1I B;  2J61 A;  2OYI C;  2HPC B;  1FZG B;  2HLO B;  1RE4 C;  4JZC A;  1JC9 A;  4M7H A;  2Q9I C;  2OYH B;  2J1G A;  3H32 C;  1LTJ B;  2HOD C;  1FZE C;  1Z3S A;  2JHL F;  1RF1 B;  1N86 C;  1FZA B;  3HUS B;  1LT9 B;  2J0G A;  4M7F A;  1FZB C;  1FIC A;  1M1J C;  1RF0 B;  4R9T A;  1FZF C;  1LWU B;  2J60 A;  2J3F D;  2XNX B;  3GHG C;  2FFD C;  3BVH B;  2J3U A;  2Z4E C;  2H43 B;  2OYI B;  4EPU A;  2D39 A;  1RE3 C;  1N73 C;  1RE4 B;  1FIB A;  2Q9I B;  2J0Y A;  2J64 A;  2J3F A;  3H32 B;  2HOD B;  1FZE B;  1N86 B;  2FIB A;  1FZC C;  3E1I C;  2HPC C;  2J0H A;  2J5Z A;  2JHK F;  2J3O A;  1FZG C;  2HLO C;  1FID A;  1M1J B;  1FZF B;  2JHH C;  2GY7 A;  1Z3U A;  2OYH C;  4R9J A;  2J61 B;  1LTJ C;  4NYT A;  2FFD B;  1RF1 C;  4JYO X;  2Z4E B;  1FZA C;  3HUS C;  1LT9 C;  1FZD A;  2JHI F;  4ZFG A;  2WNP F;  1RF0 C;  1RE3 B;  3FIB A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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