1FZEB

Crystal structure of fragment double-d from human fibrin
Total Genus 94
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
94
sequence length
309
structure length
309
Chain Sequence
LYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKMSMKIRPFFP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Conformational changes in fragments D and double-D from human fibrin(ogen) upon binding the peptide ligand Gly-His-Arg-Pro-amide.
pubmed doi rcsb
molecule tags Blood coagulation
molecule keywords FIBRINOGEN
total genus 94
structure length 309
sequence length 309
chains with identical sequence E
ec nomenclature
pdb deposition date 1998-12-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 1fzeB01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 1fzeB02
2H43C 1FZBB 3BVHC 2JHLF 4M7FA 2OYHC 1FZCB 2JHKF 1FICA 4JZCA 2HODC 2J61B 1LTJC 2OYIC 1FZGC 2WNPF 2Z4EC 2XNXB 1FZEC 2J3FA 3HUSB 4EPUA 1FZFB 1FZAC 1RF0B 4R9TA 3FIBA 1LT9B 3H32C 1N86B 1LWUC 1FZBC 2GY7A 3E1IB 1RF1B 4R9JA 1FZDA 1FZCC 2JHIF 2J3FD 2HPCB 2H43B 2HLOB 1RE3C 2D39A 1M1JB 2JHHC 2Q9IB 2J3GA 1N73B 1FZGB 1RE4B 3HUSC 2J0YA 1RF0C 2FFDB 2J61A 1N86C 2J5ZA 2J1GA 2J3OA 3GHGC 2JHMF 1FIDA 3E1IC 2J64A 1RF1C 3BVHB 2J0HA 4JYOX 1LWUB 4ZFGA 2OYHB 2HPCC 2HLOC 2J2PA 2XNXC 1M1JC 2HODB 1LTJB 1JC9A 2Q9IC 2OYIB 1N73C 2FIBA 1FZFC 2Z4EB 1RE3B 1FZEB 1LT9C 4NYTA 1RE4C 2J3UA 2FFDC 1FZAB 1FIBA 2J0GA 2J60A 1Z3SA 1Z3UA 3H32B 4M7HA
chains in the Genus database with same CATH superfamily
2H43C 1FZBB 3BVHC 2JHLF 4M7FA 2OYHC 1FZCB 2JHKF 1FICA 4JZCA 2HODC 2J61B 1LTJC 2OYIC 1FZGC 2WNPF 2Z4EC 2XNXB 1FZEC 2J3FA 3HUSB 4EPUA 1FZFB 1FZAC 1RF0B 4R9TA 3FIBA 1LT9B 3H32C 1N86B 1LWUC 3GHGB 1FZBC 2GY7A 3E1IB 1RF1B 4R9JA 1FZDA 1FZCC 2JHIF 2J3FD 2HPCB 2H43B 2HLOB 1RE3C 2D39A 1M1JB 2JHHC 2Q9IB 2J3GA 1N73B 1FZGB 1RE4B 3HUSC 2J0YA 1RF0C 2FFDB 2J61A 1N86C 2J5ZA 2J1GA 2J3OA 3GHGC 2JHMF 1FIDA 3E1IC 2J64A 1RF1C 3BVHB 2J0HA 4JYOX 1LWUB 4ZFGA 2OYHB 2HPCC 2HLOC 2J2PA 2XNXC 1M1JC 2HODB 1LTJB 1JC9A 2Q9IC 2OYIB 1N73C 2FIBA 1FZFC 2Z4EB 1RE3B 1FZEB 1LT9C 4NYTA 1RE4C 2J3UA 2FFDC 1FZAB 1FIBA 2J0GA 2J60A 1Z3SA 1Z3UA 3H32B 4M7HA
chains in the Genus database with same CATH topology
2H43C 1FZBB 3BVHC 2JHLF 4M7FA 2OYHC 1FZCB 2JHKF 1FICA 4JZCA 2HODC 2J61B 1LTJC 2OYIC 1FZGC 2WNPF 2Z4EC 2XNXB 1FZEC 2J3FA 3HUSB 4EPUA 1FZFB 1FZAC 1RF0B 4R9TA 3FIBA 1LT9B 3H32C 1N86B 1LWUC 1FZBC 2GY7A 3E1IB 1RF1B 4R9JA 1FZDA 1FZCC 2JHIF 2J3FD 2HPCB 2H43B 2HLOB 1RE3C 2D39A 1M1JB 2JHHC 2Q9IB 2J3GA 1N73B 1FZGB 1RE4B 3HUSC 2J0YA 1RF0C 2FFDB 2J61A 1N86C 2J5ZA 2J1GA 2J3OA 3GHGC 2JHMF 1FIDA 3E1IC 2J64A 1RF1C 3BVHB 2J0HA 4JYOX 1LWUB 4ZFGA 2OYHB 2HPCC 2HLOC 2J2PA 2XNXC 1M1JC 2HODB 1LTJB 1JC9A 2Q9IC 2OYIB 1N73C 2FIBA 1FZFC 2Z4EB 1RE3B 1FZEB 1LT9C 4NYTA 1RE4C 2J3UA 2FFDC 1FZAB 1FIBA 2J0GA 2J60A 1Z3SA 1Z3UA 3H32B 4M7HA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2H43 C;  1FZB B;  3BVH C;  2JHL F;  4M7F A;  2OYH C;  1FZC B;  2JHK F;  1FIC A;  4JZC A;  2HOD C;  2J61 B;  1LTJ C;  2OYI C;  1FZG C;  2WNP F;  2Z4E C;  2XNX B;  1FZE C;  2J3F A;  3HUS B;  4EPU A;  1FZF B;  1FZA C;  1RF0 B;  4R9T A;  3FIB A;  1LT9 B;  3H32 C;  1N86 B;  1LWU C;  1FZB C;  2GY7 A;  3E1I B;  1RF1 B;  4R9J A;  1FZD A;  1FZC C;  2JHI F;  2J3F D;  2HPC B;  2H43 B;  2HLO B;  1RE3 C;  2D39 A;  1M1J B;  2JHH C;  2Q9I B;  2J3G A;  1N73 B;  1FZG B;  1RE4 B;  3HUS C;  2J0Y A;  1RF0 C;  2FFD B;  2J61 A;  1N86 C;  2J5Z A;  2J1G A;  2J3O A;  3GHG C;  2JHM F;  1FID A;  3E1I C;  2J64 A;  1RF1 C;  3BVH B;  2J0H A;  4JYO X;  1LWU B;  4ZFG A;  2OYH B;  2HPC C;  2HLO C;  2J2P A;  2XNX C;  1M1J C;  2HOD B;  1LTJ B;  1JC9 A;  2Q9I C;  2OYI B;  1N73 C;  2FIB A;  1FZF C;  2Z4E B;  1RE3 B;  1FZE B;  1LT9 C;  4NYT A;  1RE4 C;  2J3U A;  2FFD C;  1FZA B;  1FIB A;  2J0G A;  2J60 A;  1Z3S A;  1Z3U A;  3H32 B;  4M7H A; 
#chains in the Genus database with same CATH topology
 2H43 C;  1FZB B;  3BVH C;  2JHL F;  4M7F A;  2OYH C;  1FZC B;  2JHK F;  1FIC A;  4JZC A;  2HOD C;  2J61 B;  1LTJ C;  2OYI C;  1FZG C;  2WNP F;  2Z4E C;  2XNX B;  1FZE C;  2J3F A;  3HUS B;  4EPU A;  1FZF B;  1FZA C;  1RF0 B;  4R9T A;  3FIB A;  1LT9 B;  3H32 C;  1N86 B;  1LWU C;  3GHG B;  1FZB C;  2GY7 A;  3E1I B;  1RF1 B;  4R9J A;  1FZD A;  1FZC C;  2JHI F;  2J3F D;  2HPC B;  2H43 B;  2HLO B;  1RE3 C;  2D39 A;  1M1J B;  2JHH C;  2Q9I B;  2J3G A;  1N73 B;  1FZG B;  1RE4 B;  3HUS C;  2J0Y A;  1RF0 C;  2FFD B;  2J61 A;  1N86 C;  2J5Z A;  2J1G A;  2J3O A;  3GHG C;  2JHM F;  1FID A;  3E1I C;  2J64 A;  1RF1 C;  3BVH B;  2J0H A;  4JYO X;  1LWU B;  4ZFG A;  2OYH B;  2HPC C;  2HLO C;  2J2P A;  2XNX C;  1M1J C;  2HOD B;  1LTJ B;  1JC9 A;  2Q9I C;  2OYI B;  1N73 C;  2FIB A;  1FZF C;  2Z4E B;  1RE3 B;  1FZE B;  1LT9 C;  4NYT A;  1RE4 C;  2J3U A;  2FFD C;  1FZA B;  1FIB A;  2J0G A;  2J60 A;  1Z3S A;  1Z3U A;  3H32 B;  4M7H A; 
#chains in the Genus database with same CATH homology
 2H43 C;  1FZB B;  3BVH C;  2JHL F;  4M7F A;  2OYH C;  1FZC B;  2JHK F;  1FIC A;  4JZC A;  2HOD C;  2J61 B;  1LTJ C;  2OYI C;  1FZG C;  2WNP F;  2Z4E C;  2XNX B;  1FZE C;  2J3F A;  3HUS B;  4EPU A;  1FZF B;  1FZA C;  1RF0 B;  4R9T A;  3FIB A;  1LT9 B;  3H32 C;  1N86 B;  1LWU C;  1FZB C;  2GY7 A;  3E1I B;  1RF1 B;  4R9J A;  1FZD A;  1FZC C;  2JHI F;  2J3F D;  2HPC B;  2H43 B;  2HLO B;  1RE3 C;  2D39 A;  1M1J B;  2JHH C;  2Q9I B;  2J3G A;  1N73 B;  1FZG B;  1RE4 B;  3HUS C;  2J0Y A;  1RF0 C;  2FFD B;  2J61 A;  1N86 C;  2J5Z A;  2J1G A;  2J3O A;  3GHG C;  2JHM F;  1FID A;  3E1I C;  2J64 A;  1RF1 C;  3BVH B;  2J0H A;  4JYO X;  1LWU B;  4ZFG A;  2OYH B;  2HPC C;  2HLO C;  2J2P A;  2XNX C;  1M1J C;  2HOD B;  1LTJ B;  1JC9 A;  2Q9I C;  2OYI B;  1N73 C;  2FIB A;  1FZF C;  2Z4E B;  1RE3 B;  1FZE B;  1LT9 C;  4NYT A;  1RE4 C;  2J3U A;  2FFD C;  1FZA B;  1FIB A;  2J0G A;  2J60 A;  1Z3S A;  1Z3U A;  3H32 B;  4M7H A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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